The document provides information about acute appendicitis including: 1. Appendicitis is an inflammation of the appendix and remains a common acute surgical condition. It has a lifetime occurrence of approximately 12% in men and 25% in women. 2. The cause is unclear but obstruction is thought to play a main role by causing inflammation. This can lead to perforation or gangrene if not treated. 3. The diagnosis is typically based on the patient's history and symptoms of abdominal pain migrating to the lower right quadrant, as well as signs on examination like tenderness at McBurney's point. Imaging studies like CT scans can help diagnose unclear cases.