Asthma is a chronic obstructive pulmonary disease caused by airway inflammation and constriction. It is the most common chronic childhood illness, with 50% of cases beginning before age 10. An asthma attack can be life-threatening and lead to respiratory failure if not properly treated. Nurses play an important role in quickly assessing severity, administering bronchodilators and other medications, monitoring the patient, providing education on triggers and ongoing management. The goals of treatment are to maintain normal lung function and prevent exacerbations and adverse effects of medications.
BRONCHIAL ASTHMA
ntroduction
Definition
Etiological factors
Pathophysiology
Types of asthma
Clinical manifestation Restlessness Wheezing or crackles Absent or diminished lung sounds Hyper resonance Use of accessory muscles for breathing Tachypnea with hyperventilation
Clinical manifestation
Diagnostic evaluation
Bronchoprovocation Testing: Testing that is done to identify inhaled allergens; mucous membranes are directly exposed to suspected allergen in increasing amounts. Skin Testing: Done to identify specific allergens. Exercise Challenges: Exercise is used to identify the occurrence of exercise-induced bronchospasm. Radio allergosorbent Test: Blood test used to identify a specific allergen. Chest Radiograph: May show hyper expansion of the airways.
Managemnet
Goal- Promote bronchodilationn Reduce inflammation Remove secretions Prevent ongoing symptoms Prevent asthma attack Maintain normal lung function Avoid triggers
Pharmacological therapy 1. Long term control medication- Inhaled corticosteroid Leukotriene modifiers Long acting beta agonist Methylxanthines Combine inhaler
2 Quick relief medication Short acting beta agonist Anticholinergic Oral or I/V corticosteroid
3 Bronchial thermoplasty- Form severe asthma that does not respond to medication
Non- pharmacological
Oxygen therapy Postural drainage & chest physiotherapy Coughing & deep breathing exercise Avoidance of allergen relaxation technique acupuncture
Prevention
Patients with recurrent asthma should undergo tests to identify the substances that precipitate the symptoms. Possible causes are dust, dust mites, roaches, certain types of cloth, pets, horses, detergents, soaps, certain foods, molds, and pol- lens. If the attacks are seasonal, pollens can be strongly sus- pected. Patients are instructed to avoid the causative agents whenever possible.
Complications Complications of asthma may include status asthmaticus, respiratory failure, pneumonia, and atelectasis. Airway obstruction, particularly during acute asthmatic episodes, often results in hypoxemia, requiring the administration of oxygen and the monitoring of pulse oximetry and arterial blood gases. Fluids are administered, because people with asthma are frequently dehydrated from diaphoresis and in- sensible fluid loss with hyperventilation.
Nursing diagnosis
Impaired gas exchange r/t altered oxygen supply Ineffective airway clearance r/t bronchospasm & obstruction from narrow lumen Ineffective breathing pattern r/t bronchospasm Risk for increasing attack of r
espiratory distress r/t exposure to allergens
BRONCHIAL ASTHMA
ntroduction
Definition
Etiological factors
Pathophysiology
Types of asthma
Clinical manifestation Restlessness Wheezing or crackles Absent or diminished lung sounds Hyper resonance Use of accessory muscles for breathing Tachypnea with hyperventilation
Clinical manifestation
Diagnostic evaluation
Bronchoprovocation Testing: Testing that is done to identify inhaled allergens; mucous membranes are directly exposed to suspected allergen in increasing amounts. Skin Testing: Done to identify specific allergens. Exercise Challenges: Exercise is used to identify the occurrence of exercise-induced bronchospasm. Radio allergosorbent Test: Blood test used to identify a specific allergen. Chest Radiograph: May show hyper expansion of the airways.
Managemnet
Goal- Promote bronchodilationn Reduce inflammation Remove secretions Prevent ongoing symptoms Prevent asthma attack Maintain normal lung function Avoid triggers
Pharmacological therapy 1. Long term control medication- Inhaled corticosteroid Leukotriene modifiers Long acting beta agonist Methylxanthines Combine inhaler
2 Quick relief medication Short acting beta agonist Anticholinergic Oral or I/V corticosteroid
3 Bronchial thermoplasty- Form severe asthma that does not respond to medication
Non- pharmacological
Oxygen therapy Postural drainage & chest physiotherapy Coughing & deep breathing exercise Avoidance of allergen relaxation technique acupuncture
Prevention
Patients with recurrent asthma should undergo tests to identify the substances that precipitate the symptoms. Possible causes are dust, dust mites, roaches, certain types of cloth, pets, horses, detergents, soaps, certain foods, molds, and pol- lens. If the attacks are seasonal, pollens can be strongly sus- pected. Patients are instructed to avoid the causative agents whenever possible.
Complications Complications of asthma may include status asthmaticus, respiratory failure, pneumonia, and atelectasis. Airway obstruction, particularly during acute asthmatic episodes, often results in hypoxemia, requiring the administration of oxygen and the monitoring of pulse oximetry and arterial blood gases. Fluids are administered, because people with asthma are frequently dehydrated from diaphoresis and in- sensible fluid loss with hyperventilation.
Nursing diagnosis
Impaired gas exchange r/t altered oxygen supply Ineffective airway clearance r/t bronchospasm & obstruction from narrow lumen Ineffective breathing pattern r/t bronchospasm Risk for increasing attack of r
espiratory distress r/t exposure to allergens
Chronic Obstructive Pulmonary Disease (COPD) is an umbrella term used to describe progressive lung diseases including emphysema, chronic bronchitis, and refractory (non-reversible) asthma. This disease is characterized by increasing breathlessness
Bronchial Asthma: Definition,Pathophysiology and ManagementMarko Makram
Definition and Pathophysiology of Asthma in addition to classification and recent updates in the management of asthma based on GINA-2019 Guidelines, by Dr. Marco Makram.
Definition and introduction to bronchial asthma - classification of bronchial asthma - pathophysiology and risk factors for bronchial asthma - diagnosis of bronchial asthma - clinical manifestations - investigations - management of bronchial asthma
Bronchiectasis is a chronic, irreversible dilation of the bronchi and bronchioles. Or •Bronchiectasis is characterized by permanent, abnormal dilation of one or more large bronchBronchiectasis.
Chronic Obstructive Pulmonary Disease (COPD) is an umbrella term used to describe progressive lung diseases including emphysema, chronic bronchitis, and refractory (non-reversible) asthma. This disease is characterized by increasing breathlessness
Bronchial Asthma: Definition,Pathophysiology and ManagementMarko Makram
Definition and Pathophysiology of Asthma in addition to classification and recent updates in the management of asthma based on GINA-2019 Guidelines, by Dr. Marco Makram.
Definition and introduction to bronchial asthma - classification of bronchial asthma - pathophysiology and risk factors for bronchial asthma - diagnosis of bronchial asthma - clinical manifestations - investigations - management of bronchial asthma
Bronchiectasis is a chronic, irreversible dilation of the bronchi and bronchioles. Or •Bronchiectasis is characterized by permanent, abnormal dilation of one or more large bronchBronchiectasis.
These lecture notes were prepared by Dr. Hamdi Turkey- Pulmonologist- Department of internal medicine - Taiz university
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Made by Ranjith R Thampi. A decent powerpoint on Bronchial Asthma, a short summary on various presentations and treatment options starting at Primary health level. Was made mainly for Primary Health setup. I've also added options at higher centres and also a few references for latest drug modalities and use.
The effects of self regulation education on use of inhaled anti-inflammatories
Noreen M. Clark
Center for Managing Chronic Disease
University of Michigan
Asthma is a chronic inflammatory condition associated with airway hyperresponsiveness (an exaggerated airway-narrowing response to specific triggers such as viruses, allergens and exercise).
Physiotherapy can provide relief from symptoms of uncontrolled asthma, including coughing, wheezing, tightness in the chest, shortness of breath and QOL.
Presentation on Treatment of Bronchial Asthma | Jindal Chest ClinicJindal Chest Clinic
Bronchial asthma is a lung disease characterized by inflammation, narrowing, swelling of airways, and increased mucus production, making it difficult to breathe. This Presentation gives an overview on "Treatment of Bronchial Asthma" including management, diagnosis, symptoms, Complications, etc. For more information, please contact us: 9779030507.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
5. Chronic, reversible obstructive pulmonary disease Caused by airway inflammation, increased airway responsiveness, or bronchospasm Most common chronic childhood illness
6. In 50 percent of patients, onset occurs before age 10 years Can be controlled, not cured Has an unpredictable course with increasing prevalence and hospitalization
20. Aspirin-induced Asthma Induced by ingestion of aspirin and related compounds “Triad” - combination of aspirin-induced asthma, nasal polyps, and sinusitis
21. Exercise-induced Asthma Symptoms vary from slight chest tightness and cough to severe wheezing/cough and shortness of breath Usually occur after 5 to 20 minutes of sustained exercise
61. Peak Expiratory Flow Rate: Measures large airway function Used to assess severity of attack and effect of treatments
62.
63. CXR Hyperinflation of the lungs may be present and is related to air being trapped in the smaller airways Show infiltrates, TB, or a pneumothorax (which can all cause shortness of breath and classify as differential diagnoses)
64. CBC Increased WBC count indicative of infection Increased eosinophils
67. Position the patient to facilitate breathing Provide humidification using a mask or open face tent Provide oxygen as indicated, and monitor the level of O2 saturation Continuously monitor all vital signs Establish and maintain IV access for medications and fluids
68. Assist the patient in removal of secretions via coughing and/or deep-breathing exercises, and suction prn Continuously monitor the ECG for cardiac dysrhythmias that are secondary to hypoxia or acidosis Monitor respiratory status for the effects of medications, pulse oximetry, and ABGs
69. Anticipate and prepare for more aggressive ventilatory support in the event that it becomes necessary. Protect the patient from environmental, pharmaceutical, and emotional irritants that may exacerbate the asthma attack. Administer medications as prescribed
70. Communicate frequently with the patient, family, and significant others and carefully explain all procedures When possible, allow a calm significant other to remain with the patient in the treatment area.
81. Should be tapered off as prescribedImportance of hydration Use of home nebulizers and peak flow meters Continuing regular medications even if they are not experiencing signs and symptoms
82. Goals of Patient Management Maintain near-normal pulmonary function and exercise levels Prevent chronic symptoms and acute exacerbations Avoid adverse effects of medications.
83. Ongoing therapy should include: Baseline measurement of lung function via PEFR Environmental control Avoidance of triggers Appropriate drugs and compliance Comprehensive patient education
84. Conclusion Although asthma is a controllable, chronic condition, when symptoms are exacerbated, they can put the patient at significant risk It is vitally important that the nurse quickly and accurately identifies the severity of the patient's situation and performs the interventions needed to prevent progression of the disease process.
85. With a thorough knowledge of symptoms, diagnostic techniques, and patient management skills, the nurse can minimize both the incidence of and the potential trauma associated with asthma emergencies.
92. Demonstrate the use of MDIs & nebulization equipment Help patient to identify what triggers asthma, warning signs of an impending attack, strategies for preventing & treating an attack Teach adaptive breathing techniques & exercises (pursed-lip breathing)
93.
94. Avoid substances and situations known to precipitate bronchospasm (allergens, irritants, strong odors, gases, fumes, smoke)
95. Wear a mask if cold weather precipitates bronchospasm
98. 1. From the list below, select the six most likely triggers for an acute asthma attack: Inhalation/pollutants Drugs Myocradial infarction Food additives Upper respiratory infection Change in atmospheric pressure Paranasal sinusitis Exercise and cold, dry air Sudden auditory stimulus
99. 2. In ______ percent of patients, onset of asthma occurs before age ______ years. 20, 21 65, 18 50, 10 40, 12
100. 3. Asthma can be cured and has a predictable course with decreasing prevalence and hospitalization. True False
101. 4. Common allergens that can trigger asthma through inhalation include all but which of the following? Animal danders House dust mites Sulfites Molds
102. 5. Types of drugs that can act as asthma triggers include: Aspirin Nonsteroidal anti-inflammatory drugs B-adrenergic blockers All of the above
103. 6. Which of the following signs does not require immediate intervention? Decrease in oxygen saturation Decrease in potassium and chloride Decrease in dry or productive cough Decreased LOC
104. 7. If untreated, ______ can lead to worsening hypoxemia, acid-base disturbance, and possible respiratory arrest. Fever Status asthmaticus Hyperresonance Cough
105. 8. Once wheezing is resolved, the patient's condition is always considered improved. True False
106. 9. An assessment of electrolytes can yield clear diagnostic results. ______ and ______ levels may be decreased with long-standing respiratory acidosis. Iron, Calcium Potassium, Chloride Folic acid, Potassium Sodium, Chloride
107. 10. When discharging an asthma patient from the ED, it is important to provide instructions and information on: Aggravating allergens Precipitating factors Asthma medications All of the above
108. 11. Corticosteroid therapy should never be stopped abruptly, but instead should be tapered off as prescribed. True False
109. 12. The goals of patient management include all but which of the following? Limit exercise levels to prevent symptom exacerbation Maintain near-normal pulmonary function Prevent chronic symptoms Avoid adverse affects of medications
110. References: Smeltzer, C.S., Bare, B.G., Hinkle, J.L., Cheever, K.H., Brunner and Suddarth’s Textbook of Medical-Surgical Nursing 11th Ed. Lippincott Williams and Wilkins, 2008. Nettina, Sandra M., Mills, Elizabeth Jacqueline. Lippincott Manual of Nursing Practice, 8th Ed.Lippincott Williams & Wilkins: 2006. Castellucci, Stacy. Asthma.MedcomTrainex Sommers, M. S., Johnson, S. A., Beery, T. A. Diseases and Disorders: A Nursing Therapeutics Manual, 3rd Ed. F. A. Davis Company: 2007.