This document discusses the approach and evaluation of arthritis. It outlines relevant factors to consider in a patient's history such as age, sex, family history, onset of symptoms, and pattern of joint involvement. It describes signs of inflammation seen in different types of arthritis and notes that examination should assess for inflammation, crepitus, range of motion, and deformity. Investigation may include x-rays, blood tests, synovial fluid analysis, and serology. Treatment is based on diagnosis and may include medications, physical therapy, or surgery.