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CLINICAL SERIES:   ARTHRITIS BY:  Ahmed AL-Jabri  R2
AIM ,[object Object],[object Object],[object Object]
Normal Joint..
Articular Vs. Periarticular Clinical feature Articular  Periarticular Anatomic structure Painful site  Pain on movement Swelling  Synovium, cartilage, capsule Diffuse, deep Active/passive, all planes Common Tendon, bursa, ligament, muscle, bone Focal “point” Active, in few planes Uncommon
Inflammatory Vs. Noninflammatory Feature Inflammatory Noninflammatory Pain (when?) Swelling Erythema Warmth AM stiffness Systemic features î  ESR, CRP Synovial fluid WBC Examples  Yes (AM) Soft tissue  Sometimes Sometimes Prominent  Sometimes Frequent WBC >2000 Septic, RA, SLE, Gout Yes (PM) Bony Absent Absent Minor (< 30  ‘) Absent Uncommon WBC < 2000 OA, AVN
Inflammatory Vs. Noninflammatory Feature Inflammatory Mechanical Morning stiffness Fatigue Activity Rest Systemic >1 h Profound  Improves Worsens Yes < 30 min Minimal Worsens Improves No
Acute Monoarthritis - differential diagnosis ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Monoarthritis - differential diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Monoarthritis - differential diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Q: Physical examination of a patient with reiter’s  syndrome may be expected to reveal :  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Q: Physical examination of a patient with reiter’s  syndrome may be expected to reveal :  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Monoarthritis - differential diagnosis ,[object Object]
Others to think about ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Is it an articular or extra-articular problem? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
WHAT DO WE HAVE ?
Olecranon bursitis
42 YRS OLD MALE  presents with pain, warmth, and swelling over his posterior  elbow. The pt reports frequntly having to lean on his elbow while performing electrical work as part of his job. Although he is able to flex and extend the joint , flexion results in increased pain. After aspiration and cell count of the fluid obtained, which of the following is the minimum WBC count suggestive of infection ? ,[object Object],[object Object],[object Object],[object Object],[object Object]
42 YRS OLD MALE  presents with pain, warmth, and swelling over his posterior  elbow. The pt reports frequntly having to lean on his elbow while performing electrical work as part of his job. Although he is able to flex and extend the joint , flexion results in increased pain. After aspiration and cell count of the fluid obtained, which of the following is the minimum WBC count suggestive of infection ? ,[object Object],[object Object],[object Object],[object Object]
What is the expected WBC counts in aspirated synovial fluid from a patient with septic arthitis ?
[object Object],[object Object],[object Object],What is the expected WBC counts in aspirated synovial fluid from a patient with septic arthitis ?
A patient presents with acute polyarthritis. Joint fluid shows less than 10,000 WBCs, mostly lymphocytes. This is most consistent with __. ,[object Object],[object Object],[object Object],[object Object],[object Object]
A patient presents with acute polyarthritis. Joint fluid shows less than 10,000 WBCs, mostly lymphocytes. This is most consistent with __. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Septic arthritis ,[object Object],[object Object],[object Object]
[object Object]
Pathogenesis
[object Object]
Who gets septic arthritis? ,[object Object],[object Object],[object Object],[object Object]
Who gets septic arthritis? ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Symptoms & signs of septic arthritis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
55 YRS OLD  female with h/o RA presents with progressive swelling and pain in her knee for 6 days. She is on prednisone and states that her standard flares involve her ankles and fingers. Her vitals are normal ; afebrile .  Examination reveals a moderate-sized knee effusion with warmth and tenderness and extreme pain on range of motion of the joint. Which of the following is the most appropriate next step in management ? ,[object Object],[object Object],[object Object],[object Object],[object Object]
55 YRS OLD  female with h/o RA presents with progressive swelling and pain in her knee for 6 days. She is on prednisone and states that her standard flares involve her ankles and fingers. Her vitals are normal ; afebrile .  Examination reveals a moderate-sized knee effusion with warmth and tenderness and extreme pain on range of motion of the joint. Which of the following is the most appropriate next step in management ? ,[object Object]
Symptoms & signs of septic arthritis ,[object Object],[object Object],[object Object]
Kocher et al. 1999 ,[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Investigations ,[object Object],[object Object],[object Object],[object Object]
Other investigations ,[object Object],[object Object],[object Object],[object Object]
Other tests? ,[object Object],[object Object],[object Object]
Antibiotic treatment of septic arthritis ,[object Object],[object Object],[object Object]
SEPTIC ARTHRITS: Oral Antibiotics ,[object Object],[object Object],[object Object],[object Object],[object Object]
Arthrocentesis ,[object Object],[object Object],[object Object],Tap
Indications  ,[object Object],[object Object],[object Object],[object Object],Tap
Arthrocentesis ,[object Object],[object Object],[object Object],Tap
Shoulder – Posterior Approach Tap
Shoulder – Anterior Approach Tap
Elbow – Lateral Approach Tap Flex elbow 90 o Prep skin Insert needle in palpable bony notch between lateral epicondyle and olecranon
Elbow – Lateral Approach Tap
Elbow – Posterior Approach Tap
Wrist Approach Tap
Wrist Approach Tap
Wrist Approach Tap
A patient has wrist inflammation that is too subtle to detect visually. It may best be detected by comparing __ to the opposite side. ,[object Object],[object Object],[object Object]
A patient has wrist inflammation that is too subtle to detect visually. It may best be detected by comparing __ to the opposite side. ,[object Object],[object Object],[object Object],[object Object]
Knee – Lateral Approach Tap
Knee – Lateral Approach Extend knee, quadriceps and patella relaxed so patella can move mediolaterally. Needle into joint space just lateral to patella near its upper pole, parallel to the posterior (articular) surface.  Tap
Knee – Lateral Approach Tap
Knee – Medial Approach Tap
Knee – Medial Approach Tap
Knee – Medial Approach Tap
Knee – Medial Approach Tap
Knee – Medial Approach Tap
Ankle Tap Palpate the medial and lateral malleoli with your thumb and index finger.  The joint space is located one to one and a half cm above the line joining the tips of the malleoli.
Ankle Tap Palpate the dorsalis pedis artery and choose a puncture site anywhere on the anterior aspect of the ankle, avoiding the dorsalis pedis artery.
Ankle – Lateral  Approach Tap
Ankle – Medial Approach Tap
Synovial Fluid Analysis ,[object Object],[object Object],[object Object],[object Object],Fluid
Synovial Fluid Cell Count ,[object Object],[object Object],[object Object],[object Object],[object Object],Fluid
Synovial Fluid Analysis Normal Non-inflammatory Inflammatory Infectious Trans-parent Transparent Cloudy Cloudy  Clear Yellow Yellow Yellow  <200 <2000 200 – 50,000 >50,000 <25% <25% >50% >50% Negative Negative Negative Positive  Appear-ance Clarity WBCs PMNs Culture
Septic arthritis: SMS ,[object Object],[object Object]
gout
Gout ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Acute Gouty Arthritis
Risk Factors ,[object Object],[object Object]
Microscopic appearance of the crystals of gout include all of the following EXCEPT: ,[object Object],[object Object],[object Object],[object Object]
Microscopic appearance of the crystals of gout include all of the following EXCEPT: ,[object Object],[object Object]
Urate Crystals ,[object Object],[object Object]
CPPD Crystals Deposition Disease ,[object Object],[object Object],[object Object],[object Object],[object Object]
Associated Conditions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CPPD Crystals ,[object Object],[object Object]
[object Object]

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