An overview of agricultural applications of genome editing: Farm animals OECD Environment
The presentation will give an overview of genome editing applications in relation to farm animals. It will give an overview of some examples of agricultural applications that may be on or close to the market or under research and development. It will also consider the possibility of foreseeing future applications (e.g. variations in CRISPR/Cas applications, DNA-free
application, agricultural pest control), if possible.
Presented by Raphael Mrode, ILRI, at the workshop on Essential Knowledge for Effective Improvement and Dissemination of Genetics in Sheep and Goats, Addis Ababa, Ethiopia, 3–5 November 2020
Conservation of farm animal genetic resourcesIllaya Kumar
India is a vast country, rich in biodiversity. With its geographical area of 329 million hectares, India has almost all the climatic conditions and ecological zones found in different parts of the world, ranging from perpetual snow cover to equatorial and tropical conditions, from mangroves to humid tropics and hot and cold deserts as well as all the intermediate conditions. Before the advent of fossil fuel, animal energy was the only source of farm power and that also mainly from bullocks. In the recent past, a number of native breeds are facing fast genetic degradation and dilution because of intensive production system and unplanned introduction and use of exotic germplasm. This scenario, if continued, might result in depletion of the invaluable native germplasm having better potentiality for production, draught capacity, resistance to diseases and heat tolerance ability. In general, indigenous breeds provide the necessary genetic diversity needed by modern agriculture as a means to ensure stability and are vital building blocks for future livestock breeding programmes. Conservation of indigenous animal is needed for Genetic insurance, Scientific study, Economic potential, Environmental considerations, Cultural and ethical requirements, Energy source by In situ or Ex situ conservation techniques. There are some agencies like NBAGR involved in livestock conservation and the government also implemented projects for breeds conservation. There are many successful stories such as Sabarmathi Ashram goshala in the conservation of native breeds. Many foreign countries have realized the genetic potential of our indigenous breeds and using them for improvement of their germplasm. It is high time to proceed to conserve our germplasm.
it cover almost all content in cis/intragesis, right from introduction definition, explanation, production of marker free transgenic, intragenic vector construction, regulatory guide lines, current and future status, limitation, advantage over existing technique, swot analysis etc
its very useful for your seminar and presentations. it contain lot of picture, table, figure for your easy understanding
thank you
Mahesh
An overview of agricultural applications of genome editing: Farm animals OECD Environment
The presentation will give an overview of genome editing applications in relation to farm animals. It will give an overview of some examples of agricultural applications that may be on or close to the market or under research and development. It will also consider the possibility of foreseeing future applications (e.g. variations in CRISPR/Cas applications, DNA-free
application, agricultural pest control), if possible.
Presented by Raphael Mrode, ILRI, at the workshop on Essential Knowledge for Effective Improvement and Dissemination of Genetics in Sheep and Goats, Addis Ababa, Ethiopia, 3–5 November 2020
Conservation of farm animal genetic resourcesIllaya Kumar
India is a vast country, rich in biodiversity. With its geographical area of 329 million hectares, India has almost all the climatic conditions and ecological zones found in different parts of the world, ranging from perpetual snow cover to equatorial and tropical conditions, from mangroves to humid tropics and hot and cold deserts as well as all the intermediate conditions. Before the advent of fossil fuel, animal energy was the only source of farm power and that also mainly from bullocks. In the recent past, a number of native breeds are facing fast genetic degradation and dilution because of intensive production system and unplanned introduction and use of exotic germplasm. This scenario, if continued, might result in depletion of the invaluable native germplasm having better potentiality for production, draught capacity, resistance to diseases and heat tolerance ability. In general, indigenous breeds provide the necessary genetic diversity needed by modern agriculture as a means to ensure stability and are vital building blocks for future livestock breeding programmes. Conservation of indigenous animal is needed for Genetic insurance, Scientific study, Economic potential, Environmental considerations, Cultural and ethical requirements, Energy source by In situ or Ex situ conservation techniques. There are some agencies like NBAGR involved in livestock conservation and the government also implemented projects for breeds conservation. There are many successful stories such as Sabarmathi Ashram goshala in the conservation of native breeds. Many foreign countries have realized the genetic potential of our indigenous breeds and using them for improvement of their germplasm. It is high time to proceed to conserve our germplasm.
it cover almost all content in cis/intragesis, right from introduction definition, explanation, production of marker free transgenic, intragenic vector construction, regulatory guide lines, current and future status, limitation, advantage over existing technique, swot analysis etc
its very useful for your seminar and presentations. it contain lot of picture, table, figure for your easy understanding
thank you
Mahesh
Genetically modified food or GM food is a very popular name nowadays. its been popular because of its controversy. Some scientists support this technology and some don't. That's why this slide showing it why it is controversial. this presentation contains information about GM food, its use, its benefit, its harmfulness and although why we should use this technology.
Introduction:
Proposed by Meuwissen et al. (2001)
GS is a specialized form of MAS, in which information from genotype data on marker alleles covering the entire genome forms the basis of selection.
The effects associated with all the marker loci, irrespective of whether the effects are significant or not, covering the entire genome are estimated.
The marker effect estimates are used to calculate the genomic estimated breeding values (GEBVs) of different individuals/lines, which form the basis of selection.
Why to go for genomic selection:
Marker-assisted selection (MAS) is well-suited for handling oligogenes and quantitative trait loci (QTLs) with large effects but not for minor QTLs.
MARS attempts to take into account small effect QTLs by combining trait phenotype data with marker genotype data into a combined selection index.
Based on markers showing significant association with the trait(s) and for this reason has been criticized as inefficient
The genomic selection (GS) scheme was to rectify the deficiency of MAS and MARS schemes. The GS scheme utilizes information from genome-wide marker data whether or not their associations with the concerned trait(s) are significant.
GEBV: GenomicEstimated Breeding Values-
The sum total of effects associated with all the marker alleles present in the individual and included in the GS model applied to the population under selection
Calculated on a single individual basis
Gene-assisted genomic selection:
A GS model that uses information about prior known QTLs, the targeted QTLs were accumulated in much higher frequencies than when the standard ridge regression was used
The sum total of effects associated with all the marker alleles present in the individual and included in the GS model applied to the population under selection
Calculated on a single individual basis
Population used:
Training population: used for training of the GS model and for obtaining estimates of the marker-associated effects needed for estimation of GEBVs of individuals/lines in the breeding population.
Breeding population: the population subjected to GS for achieving the desired improvement and isolation of superior lines for use as new varieties/parents of new improved hybrids.
Training population-
large enough: must be representative of the breeding population: max. trait variance with marker : by cluster analysis
should have either equal or comparable LD, LD decay rates with breeding populations
Updated by including individuals/lines from the breeding population
Training more than one generation
Low colinearity between markers is needed since high colinearity tends to reduce prediction accuracy of certain GS models. (colinearity disturbed by recombination)
Practical application of advanced molecular techniques in the improvement of ...ILRI
Presented by Tadelle Dessie, Mengistie Taye, Adebabay Kebede, Kefena Effa, Zewdu Edea and Wondmeneh Esatu at the 27 Annual Conference of the Ethiopian Society of Animal Production (ESAP), EIAR, Addis Ababa, 29–31 August 2019
Genetic basis and improvement of reproductive traitsILRI
Presented by Aynalem Haile and Mourad Rekik (ICARDA) at the EIAR-DBARC-ICARDA-ILRI (LIVES)-FAO Training Workshop on Reproduction in Sheep and Goat, Debre Berhan, Ethiopia, 13-15 October 2014
Presentation delivered by Dr. Jesse Poland (Kansas State University, USA) at Borlaug Summit on Wheat for Food Security. March 25 - 28, 2014, Ciudad Obregon, Mexico.
http://www.borlaug100.org
Genomics and its application in crop improvementKhemlata20
meaning ,definition of genome ,genomics ,tools of genomics ,what is genome sequencing ,methods of genome sequencingand genome mapping ,advantage of genomics over traditional breeding program, examples of some crops whose genome has been sequenced, important points about genomics, work in the field of genomics ,applications of genomics .classification of genomics .different Omics in genomics like Proteomics ,Transcriptomics ,Metabolomics ,Need of genome sequencing
An Overview of Genomic Selection and FertilityDAIReXNET
In this webinar, released July 18, 2016, Dr. Hansen joined us to discuss genomic selection as it relates to fertility traits. Learn about single nucleotide polymorphisms (SNPs), the challenges in selecting for reproductive traits, and some of the current work in overcoming those challenges.
Dr. Alison Van Eenennaam - Were Those the Days? Animal Ag Then & NowJohn Blue
Were Those the Days? Animal Ag Then & Now - Dr. Alison Van Eenennaam, Cooperative Extension Specialist, Animal Genomics and Biotechnology, University of California, Davis, From the 2018 Animal Agriculture Alliance Stakeholders Summit, Protect Your Roots, May 3 - 4, 2018, Arlington, VA, USA.
More presentations at https://www.youtube.com/channel/UC9xWTLbiBMQQi8L_WHIWcjA
Were those the days? Agriculture Then and NowJohn Blue
Were those the days? Agriculture Then and Now - Dr. Alison Van Eenennaam, University of California, Davis, from the 2019 Iowa Pork Congress, January 23 - 24, 2019, Des Moines, IA, USA.
More presentations at https://www.youtube.com/channel/UCEFNbfee_Rq3AfAFTRpuCrQ
Genetically modified food or GM food is a very popular name nowadays. its been popular because of its controversy. Some scientists support this technology and some don't. That's why this slide showing it why it is controversial. this presentation contains information about GM food, its use, its benefit, its harmfulness and although why we should use this technology.
Introduction:
Proposed by Meuwissen et al. (2001)
GS is a specialized form of MAS, in which information from genotype data on marker alleles covering the entire genome forms the basis of selection.
The effects associated with all the marker loci, irrespective of whether the effects are significant or not, covering the entire genome are estimated.
The marker effect estimates are used to calculate the genomic estimated breeding values (GEBVs) of different individuals/lines, which form the basis of selection.
Why to go for genomic selection:
Marker-assisted selection (MAS) is well-suited for handling oligogenes and quantitative trait loci (QTLs) with large effects but not for minor QTLs.
MARS attempts to take into account small effect QTLs by combining trait phenotype data with marker genotype data into a combined selection index.
Based on markers showing significant association with the trait(s) and for this reason has been criticized as inefficient
The genomic selection (GS) scheme was to rectify the deficiency of MAS and MARS schemes. The GS scheme utilizes information from genome-wide marker data whether or not their associations with the concerned trait(s) are significant.
GEBV: GenomicEstimated Breeding Values-
The sum total of effects associated with all the marker alleles present in the individual and included in the GS model applied to the population under selection
Calculated on a single individual basis
Gene-assisted genomic selection:
A GS model that uses information about prior known QTLs, the targeted QTLs were accumulated in much higher frequencies than when the standard ridge regression was used
The sum total of effects associated with all the marker alleles present in the individual and included in the GS model applied to the population under selection
Calculated on a single individual basis
Population used:
Training population: used for training of the GS model and for obtaining estimates of the marker-associated effects needed for estimation of GEBVs of individuals/lines in the breeding population.
Breeding population: the population subjected to GS for achieving the desired improvement and isolation of superior lines for use as new varieties/parents of new improved hybrids.
Training population-
large enough: must be representative of the breeding population: max. trait variance with marker : by cluster analysis
should have either equal or comparable LD, LD decay rates with breeding populations
Updated by including individuals/lines from the breeding population
Training more than one generation
Low colinearity between markers is needed since high colinearity tends to reduce prediction accuracy of certain GS models. (colinearity disturbed by recombination)
Practical application of advanced molecular techniques in the improvement of ...ILRI
Presented by Tadelle Dessie, Mengistie Taye, Adebabay Kebede, Kefena Effa, Zewdu Edea and Wondmeneh Esatu at the 27 Annual Conference of the Ethiopian Society of Animal Production (ESAP), EIAR, Addis Ababa, 29–31 August 2019
Genetic basis and improvement of reproductive traitsILRI
Presented by Aynalem Haile and Mourad Rekik (ICARDA) at the EIAR-DBARC-ICARDA-ILRI (LIVES)-FAO Training Workshop on Reproduction in Sheep and Goat, Debre Berhan, Ethiopia, 13-15 October 2014
Presentation delivered by Dr. Jesse Poland (Kansas State University, USA) at Borlaug Summit on Wheat for Food Security. March 25 - 28, 2014, Ciudad Obregon, Mexico.
http://www.borlaug100.org
Genomics and its application in crop improvementKhemlata20
meaning ,definition of genome ,genomics ,tools of genomics ,what is genome sequencing ,methods of genome sequencingand genome mapping ,advantage of genomics over traditional breeding program, examples of some crops whose genome has been sequenced, important points about genomics, work in the field of genomics ,applications of genomics .classification of genomics .different Omics in genomics like Proteomics ,Transcriptomics ,Metabolomics ,Need of genome sequencing
An Overview of Genomic Selection and FertilityDAIReXNET
In this webinar, released July 18, 2016, Dr. Hansen joined us to discuss genomic selection as it relates to fertility traits. Learn about single nucleotide polymorphisms (SNPs), the challenges in selecting for reproductive traits, and some of the current work in overcoming those challenges.
Dr. Alison Van Eenennaam - Were Those the Days? Animal Ag Then & NowJohn Blue
Were Those the Days? Animal Ag Then & Now - Dr. Alison Van Eenennaam, Cooperative Extension Specialist, Animal Genomics and Biotechnology, University of California, Davis, From the 2018 Animal Agriculture Alliance Stakeholders Summit, Protect Your Roots, May 3 - 4, 2018, Arlington, VA, USA.
More presentations at https://www.youtube.com/channel/UC9xWTLbiBMQQi8L_WHIWcjA
Were those the days? Agriculture Then and NowJohn Blue
Were those the days? Agriculture Then and Now - Dr. Alison Van Eenennaam, University of California, Davis, from the 2019 Iowa Pork Congress, January 23 - 24, 2019, Des Moines, IA, USA.
More presentations at https://www.youtube.com/channel/UCEFNbfee_Rq3AfAFTRpuCrQ
Characterization and Validation of Point Mutation in Breast Cancer 1 (BRCA1) ...paperpublications3
Abstract: Bovine mastitis is a very common and multietiological disease of dairy cattle which leads to huge economic losses to the dairy industry globally. In this study, the bovine breast cancer 1, early onset gene (BRCA1) was taken as a candidate gene for mastitis resistance. Breast cancer 1 (BRCA1) is one of the genes which predispose organism to early-onset breast cancer, and is involved in DNA damage repair, cell cycle regulation, transcriptional regulation, and other important pathways to suppress tumor and maintain genome stability. A total of 120 Sahiwal cattle were selected to characterize the targeted region of intron 6 of BRCA1 gene for polymorphism screening and their association with mastitis. A 321bp PCR fragment of BRCA1 gene encompassing the targeted region of intron 6 was amplified and digested with Hha I to screen for the reported SNPs having significant association with SCS. Genotype analysis using PCR-RFLP revealed a monomorphic banding pattern. Sequencing was also carried out to explore the in silico screened SNPs which are deposited in dbSNP. The result indicates highly conserved sequence in Sahiwal cattle. Therefore, reported as well as in silico SNPs cannot be considered as a universal marker for mastitis in all the breeds. Since, present study has formulated the results based on a relatively small sample; further studies are required to screen these SNPs in large samples.
Meat and milk from farmed animals including livestock (cattle, goat and buffalo) and poultry are sources of high quality protein and essential amino acids, minerals, fats and fatty acids, readily available vitamins, small quantities of carbohydrates and other bioactive components.1 The Food and Agriculture Organization (FAO) 2008 estimate shows that meat consumption has grown with increase in population. The average global per capita meat consumption is 42.1 kg/year with 82.9 kg/year in developed and 31.1 kg/year in developing countries in a recommended daily animal-sourced protein per capita of 50 kg per year2. Milk on the other hand is consumed in various forms: liquid, cheese, powder, and cream at a global per capita consumption of 108 kg per person per year which is way below the FAO recommended daily consumption of 200 kg.
Meat and milk from farmed animals including livestock (cattle, goat and buffalo) and poultry are sources of high quality protein and essential amino acids, minerals, fats and fatty acids, readily available vitamins, small quantities of carbohydrates and other bioactive components.1 The Food and Agriculture Organization (FAO) 2008 estimate shows that meat consumption has grown with increase in population. The average global per capita meat consumption is 42.1 kg/year with 82.9 kg/year in developed and 31.1 kg/year in developing countries in a recommended daily animal-sourced protein per capita of 50 kg per year2. Milk on the other hand is consumed in various forms: liquid, cheese, powder, and cream at a global per capita consumption of 108 kg per person per year which is way below the FAO recommended daily consumption of 200 kg.
Dr. Alison Van Eenennaam - The GMO Debate: Twenty Years of Animal Health and ...John Blue
The GMO Debate: Twenty Years of Animal Health and Livestock Feeding Studies - Dr. Alison Van Eenennaam, Cooperative Extension Specialist, Animal Biotechnology and Genomics, Department of Animal Science, University of California, Davis, USA, from the 2016 Allen D. Leman Swine Conference, September 17-20, 2016, St. Paul, Minnesota, USA.
More presentations at http://www.swinecast.com/2016-leman-swine-conference-material
Dr. Alison Van Eenennaam - Can Biotechnology Bring Home the Bacon? - Without ...John Blue
Can Biotechnology Bring Home the Bacon? - Without Netflix Clip - Dr. Alison Van Eenennaam, University of California, Davis, from the 2017 North American PRRS/National Swine Improvement Federation Joint Meeting, December 1‐3, 2017, Chicago, Illinois, USA.
More presentations at http://www.swinecast.com/2017-north-american-prrs-nsif-joint-meeting
This is about methods of creating transgenic animals,applications of transgenic animals in biotechnology and application of transgenic animals in pharmaceuticals.
Livestock sector is an important sector in indian economy. To boost the productive performance of existing livestock population in india, biotechnolgy plays a key role to fullfill this.
Current Research in Genomic Selection- Dr. Joe DaltonDAIReXNET
Dr. Dalton presented this material for a DAIReXNET webinar. You can view the recorded webinar on YouTube at https://www.youtube.com/watch?v=BL1jb8WY8lk
Dr. Alison Van Eenennaam - What Role Will Animal Biotechnology Play in Feedin...John Blue
What Role Will Animal Biotechnology Play in Feeding the World? - Dr. Alison Van Eenennaam, Cooperative Extension Specialist, Animal Genomics & Biotechnology, Department of Animal Science, University of California - Davis, from the 2013 NIAA Merging Values and Technology conference, April 15-17, 2013, Louisville, KY, USA.
More presentations at http://www.trufflemedia.com/agmedia/conference/2013-niaa-merging-values-and-technology
OECD Green Talks LIVE | Diving deeper: the evolving landscape for assessing w...OECD Environment
Water is critical for meeting commitments of the Paris Agreement and achieving the Sustainable Development Goals. Our economies rely on water, with recent estimates putting the economic value of water and freshwater ecosystems at USD 58 trillion - equivalent to 60% of global GDP. At the same time, water related risks are increasing in frequency and scale in the context of climate change.
How are investments shaping our economies and societies exposure to water risk? What role can the financial system play in supporting water security? And how can increased understanding of how finance both impacts and depends on water resources spur action towards greater water security?
This OECD Green Talks LIVE on Tuesday 14 May 2024 from 15:00 to 16:00 CEST discussed the evolving landscape for assessing water risks to the financial system.
OECD Policy Analyst Lylah Davies presented key findings and recommendations from recent OECD work on assessing the financial materiality of water-related risks, including the recently published paper “Watered down? Investigating the financial materiality of water-related risks” and was joined by experts to discuss relevant initiatives underway.
Detlef Van Vuuren- Integrated modelling for interrelated crises.pdfOECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Thomas Hertel- Integrated Policies for the Triple Planetary Crisis.pdfOECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Jon Sampedro - Assessing synergies and trade offs for health and sustainable ...OECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Astrid Bos - Identifying trade offs & searching for synergies.pdfOECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Ruth Delzeit - Modelling environmental and socio-economic impacts of cropland...OECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Wilfried Winiwarter - Implementing nitrogen pollution control pathways in the...OECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Laurent Drouet - Physical and Economic Risks of Climate Change.pdfOECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
HyeJin Kim and Simon Smart - The biodiversity nexus across multiple drivers: ...OECD Environment
This OECD technical workshop will bring together leading experts on economic, biophysical, and integrated assessment modelling of the interactions between climate change, biodiversity loss, and pollution. The workshop will take stock of ongoing modelling efforts to develop quantitative pathways to study the drivers and impacts of the triple planetary crisis, and the policies to address it. The aim is to identify robust modelling approaches to inform the work for the upcoming OECD Environmental Outlook.
Case Study: Peptides-based Plant Protection Product (harpin proteins*) by Ros...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
CLE Contribution on the Assessment of Innovative Biochemicals in the EU Statu...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
Additional Considerations for Pesticide Formulations Containing Microbial Pes...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
Role of genome sequencing (WGS) in microbial biopesticides safety assessment ...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
Considerations for Problem Formulation for Human Health Safety Assessments of...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
How to Identify and Quantify Mixtures What is Essential to Know for Risk Asse...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
APVMA outcome-focussed approach to data requirements to support registration ...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
The U.S. Perspective on Problem Formulation for Biopesticides: Shannon BORGESOECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
Problem formulation for environmental risk assessment – Finnish case study: ...OECD Environment
The seminar on Problem Formulation for the Risk Assessment of Biopesticides stemmed from a previous CRP-sponsored event on Innovating Microbial Pesticide Testing that identified the need for an overarching guidance document to determine when in vivo tests are necessary. Problem Formulation, a common practice in pesticide risk assessment, was highlighted as a useful approach for addressing uncertainties in data requirements for biopesticides.
The seminar featured presentations from various perspectives, including industry, regulatory bodies, and academia. Topics included the history and principles of Problem Formulation, industry perspectives on Problem Formulation and how it is applied internally for microbial pesticides, regulatory approaches, and specific case studies. The seminar provided an overview of the challenges, considerations, and potential solutions in harmonising Problem Formulation for biopesticide risk assessment. It emphasised the need for collaboration and discussion to develop Problem Formulation guidance for biopesticides.
UNDERSTANDING WHAT GREEN WASHING IS!.pdfJulietMogola
Many companies today use green washing to lure the public into thinking they are conserving the environment but in real sense they are doing more harm. There have been such several cases from very big companies here in Kenya and also globally. This ranges from various sectors from manufacturing and goes to consumer products. Educating people on greenwashing will enable people to make better choices based on their analysis and not on what they see on marketing sites.
"Understanding the Carbon Cycle: Processes, Human Impacts, and Strategies for...MMariSelvam4
The carbon cycle is a critical component of Earth's environmental system, governing the movement and transformation of carbon through various reservoirs, including the atmosphere, oceans, soil, and living organisms. This complex cycle involves several key processes such as photosynthesis, respiration, decomposition, and carbon sequestration, each contributing to the regulation of carbon levels on the planet.
Human activities, particularly fossil fuel combustion and deforestation, have significantly altered the natural carbon cycle, leading to increased atmospheric carbon dioxide concentrations and driving climate change. Understanding the intricacies of the carbon cycle is essential for assessing the impacts of these changes and developing effective mitigation strategies.
By studying the carbon cycle, scientists can identify carbon sources and sinks, measure carbon fluxes, and predict future trends. This knowledge is crucial for crafting policies aimed at reducing carbon emissions, enhancing carbon storage, and promoting sustainable practices. The carbon cycle's interplay with climate systems, ecosystems, and human activities underscores its importance in maintaining a stable and healthy planet.
In-depth exploration of the carbon cycle reveals the delicate balance required to sustain life and the urgent need to address anthropogenic influences. Through research, education, and policy, we can work towards restoring equilibrium in the carbon cycle and ensuring a sustainable future for generations to come.
Willie Nelson Net Worth: A Journey Through Music, Movies, and Business Venturesgreendigital
Willie Nelson is a name that resonates within the world of music and entertainment. Known for his unique voice, and masterful guitar skills. and an extraordinary career spanning several decades. Nelson has become a legend in the country music scene. But, his influence extends far beyond the realm of music. with ventures in acting, writing, activism, and business. This comprehensive article delves into Willie Nelson net worth. exploring the various facets of his career that have contributed to his large fortune.
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Introduction
Willie Nelson net worth is a testament to his enduring influence and success in many fields. Born on April 29, 1933, in Abbott, Texas. Nelson's journey from a humble beginning to becoming one of the most iconic figures in American music is nothing short of inspirational. His net worth, which estimated to be around $25 million as of 2024. reflects a career that is as diverse as it is prolific.
Early Life and Musical Beginnings
Humble Origins
Willie Hugh Nelson was born during the Great Depression. a time of significant economic hardship in the United States. Raised by his grandparents. Nelson found solace and inspiration in music from an early age. His grandmother taught him to play the guitar. setting the stage for what would become an illustrious career.
First Steps in Music
Nelson's initial foray into the music industry was fraught with challenges. He moved to Nashville, Tennessee, to pursue his dreams, but success did not come . Working as a songwriter, Nelson penned hits for other artists. which helped him gain a foothold in the competitive music scene. His songwriting skills contributed to his early earnings. laying the foundation for his net worth.
Rise to Stardom
Breakthrough Albums
The 1970s marked a turning point in Willie Nelson's career. His albums "Shotgun Willie" (1973), "Red Headed Stranger" (1975). and "Stardust" (1978) received critical acclaim and commercial success. These albums not only solidified his position in the country music genre. but also introduced his music to a broader audience. The success of these albums played a crucial role in boosting Willie Nelson net worth.
Iconic Songs
Willie Nelson net worth is also attributed to his extensive catalog of hit songs. Tracks like "Blue Eyes Crying in the Rain," "On the Road Again," and "Always on My Mind" have become timeless classics. These songs have not only earned Nelson large royalties but have also ensured his continued relevance in the music industry.
Acting and Film Career
Hollywood Ventures
In addition to his music career, Willie Nelson has also made a mark in Hollywood. His distinctive personality and on-screen presence have landed him roles in several films and television shows. Notable appearances include roles in "The Electric Horseman" (1979), "Honeysuckle Rose" (1980), and "Barbarosa" (1982). These acting gigs have added a significant amount to Willie Nelson net worth.
Television Appearances
Nelson's char
Natural farming @ Dr. Siddhartha S. Jena.pptxsidjena70
A brief about organic farming/ Natural farming/ Zero budget natural farming/ Subash Palekar Natural farming which keeps us and environment safe and healthy. Next gen Agricultural practices of chemical free farming.
WRI’s brand new “Food Service Playbook for Promoting Sustainable Food Choices” gives food service operators the very latest strategies for creating dining environments that empower consumers to choose sustainable, plant-rich dishes. This research builds off our first guide for food service, now with industry experience and insights from nearly 350 academic trials.
Characterization and the Kinetics of drying at the drying oven and with micro...Open Access Research Paper
The objective of this work is to contribute to valorization de Nephelium lappaceum by the characterization of kinetics of drying of seeds of Nephelium lappaceum. The seeds were dehydrated until a constant mass respectively in a drying oven and a microwawe oven. The temperatures and the powers of drying are respectively: 50, 60 and 70°C and 140, 280 and 420 W. The results show that the curves of drying of seeds of Nephelium lappaceum do not present a phase of constant kinetics. The coefficients of diffusion vary between 2.09.10-8 to 2.98. 10-8m-2/s in the interval of 50°C at 70°C and between 4.83×10-07 at 9.04×10-07 m-8/s for the powers going of 140 W with 420 W the relation between Arrhenius and a value of energy of activation of 16.49 kJ. mol-1 expressed the effect of the temperature on effective diffusivity.
Artificial Reefs by Kuddle Life Foundation - May 2024punit537210
Situated in Pondicherry, India, Kuddle Life Foundation is a charitable, non-profit and non-governmental organization (NGO) dedicated to improving the living standards of coastal communities and simultaneously placing a strong emphasis on the protection of marine ecosystems.
One of the key areas we work in is Artificial Reefs. This presentation captures our journey so far and our learnings. We hope you get as excited about marine conservation and artificial reefs as we are.
Please visit our website: https://kuddlelife.org
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and write to us if you have any questions:
info@kuddlelife.org
DRAFT NRW Recreation Strategy - People and Nature thriving together
Application of genome editing in farm animals: Cattle - Alison Van Eenennaam
1. Animal Genomics and Biotechnology Education
Application of genome editing
in farm animals: Cattle
Alison Van Eenennaam, Ph.D.
Cooperative Extension Specialist
Animal Biotechnology and Genomics
Department of Animal Science
University of California, Davis, USA
Email: alvaneenennaam@ucdavis.edu
Twitter: @BioBeef BLOG: http://biobeef.faculty.ucdavis.edu
http://animalscience.ucdavis.edu/animalbiotech
Van Eenennaam 6/28/2018
2. Egg, beef, pork, chicken, fish and milk
production since 1980 and projected to 2050
(FAO 2018; Alexandratos and Bruinsma, 2012).
Van Eenennaam 6/28/2018 Animal Genomics and Biotechnology Education
3. Animal Biotechnology and Genomics Education
Demand for animal-derived food in 2050 could
be 70% higher than 2005 levels , & the demand
for beef could grow by as much as 66%
(Alexandratos and Bruinsma, 2012).
• Milk and meat from cattle & buffaloes contribute 45% of the global
animal protein supply [followed by chickens (31%), and pigs (20%)].
• In 2016, the global cattle population of 1.5 billion head produced
6.5 billion tons of cows’ milk, and 66 million tons of beef.
• In the past century, cattle breeding programs have greatly increased
the yield per animal with a resultant decrease in the emissions
intensity per unit of milk or beef, but not been true in all regions
We need to accelerate the rate of genetic
gain in global cattle breeding programs
Van Eenennaam 6/28/2018
4. Animal Biotechnology and Genomics Education
Negative correlation between milk yield
(production) and carbon footprint/kg milk.
(Capper and Bowman, 2013 )
Van Eenennaam 6/28/2018
5. Animal Biotechnology and Genomics Education
1988 Grand Champion Bull, National
Polled Hereford Show (frame 10).
1986. "Coblepond New Yorker"
weighed 2529 lbs and measured 65
inches tall at 35 mos. (Frame 10)
when he was Denver Champion.
1953. Grand Champion Angus
Female, International, 1953
1950. Grand Champion Steer,
International, weighing 1025 lbs
Images from Harlan Ritchie’s historical review of type
https://www.msu.edu/~ritchieh/historical/cattletype.html
Van Eenennaam 6/28/2018
6. Van Eenennaam 6/28/2018
US Cattle Inventory 1961 – 2015
Stocks Down (Million head; blue, left) vs.
Production Up (Million Tonnes; red, right)
Animal Genomics and Biotechnology Education
USDA FAS Beef and Veal Production - Selected Countries Summary -
https://apps.fas.usda.gov/psdonline/app/index.html#/app/downloads
7. Van Eenennaam 6/28/2018
2016 Global Beef Production Numbers
Cattle numbers (Million Head; blue, left)
vs. Beef production (Million Tonnes; red, right)
Animal Genomics and Biotechnology Education
FAOSTAT 2/28/2018
8. Animal Biotechnology and Genomics Education
Genetic change per year =
(√Reliability x Intensity x Genetic Variation)
Generation Interval
reliability = how certain we are about our estimate
of an animal’s genetic merit
selection intensity = function of fraction selected
genetic variance = [can change using editing!]
generation interval = time between generations
Van Eenennaam 6/28/2018
The rate of genetic gain depends
upon the four components of the
breeders’ equation
9. Animal Biotechnology and Genomics Education
Kasinathan, P. et al. 2015. Acceleration of genetic gain in cattle by
reduction of generation interval. Sci. Rep. 5, 8674; DOI:10.1038/srep08674
Van Eenennaam 6/28/2018
10. Animal Biotechnology and Genomics Education
Approaches for genome editing cattle
Van Eenennaam 6/28/2018
Yum SY, Youn KY, Choi WJ, Jang G. 2018. Development of genome engineering
technologies in cattle: from random to specific. J Anim Sci Biotechnol. 9:16.
Somatic cell nuclear
transfer (SCNT)
Microinjection (MI)
into embryo
11. Van Eenennaam 6/28/2018
Van Eenennaam, A. L. 2017. Genetic Modification of Food Animals. Current Opinion in Biotechnology. 44:27-34.
How might gene editing be integrated with
genomic selection programs?
12. Editing is the Cherry on Top of Breeding Sundae
It will be able to introduce useful alleles without
linkage drag, and potentially bring in useful novel
genetic variation from other species
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018
Artificial insemination
Performance recording
Development of breeding goals
Progeny testing
Somatic cell nuclear transfer cloning
Embryo Transfer
Genomic Selection
Genome Editing
Association of like minded breeders
13. Accelerated rate of gain when promoting
1-20 genome edits in genomic selection
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018
Jenko, J. et a. 2015. Potential of promotion of alleles by genome editing to improve quantitative
traits in livestock breeding programs. Genetics Selection Evolution 47: 1-14.
14. Animal Biotechnology and Genomics Education
How might gene editing be
used in cattle breeding?
Updated and modified from Van Eenennaam, A. L. 2017. Genetic Modification of Food Animals. Current Opinion in
Biotechnology. 44:27-34.
Target Targeted Trait/Goal Reference
Intraspecies POLLED allele substitution No horns/welfare trait Carlson et al., 2016
Intraspecies SLICK allele substitution Heat tolerance Sonstegard et al., 2017
Myostatin (MSTN) gene knockout Increased lean muscle yield Proudfoot et al., 2014
Beta-lactoglobulin gene knockout Elimination of milk allergen Yu et al., 2011
Prion protein (PRNP) knockout Elimination of prion protein Bevacqua et al., 2016
Intraspecies CALPAIN & CAPASTATIN allele
substitution
Improved meat tenderness Casas et al., 2006 (not
reduced to practice)
Insertion of lysostaphin/lysozyme transgene Resistance to mastitis Liu et al., 2013 &2014
CD18 gene edit Resistance to bovine respiratory
disease
Shanthalingam et al.,
2016
Insertion of SP110, NRAMP1 Resistance to tuberculosis Wu et al., 2015; Gao et
al., 2017
Intraspecies SRY translocation onto Y
chromosome
All male offspring Owen et al., 2018
NANOS gene knockout Infertile males (for gonial cell
transfer)
Ideta et al., 2016
Van Eenennaam 6/28/2018
15. Animal Biotechnology and Genomics Education
What is the problem we are trying to solve?
Carlson DF, Lancto CA, Zang B, Kim E-S, Walton M, et al. 2016. Production of hornless dairy cattle
from genome-edited cell lines. Nat Biotech 34: 479-81
Need to manually remove horns from dairy calves
to protect human handlers and other animals
Van Eenennaam 6/28/2018
17. Celtic allele (PC) corresponding to a duplication of 212 bp
(chromosome 1 position 1705834–1706045) in place of a
10-bp sequence = horned (1706051–1706060) at POLLED
TALENs introgress
Pc Polled allele
bovine fibroblast
Cell line
Somatic Cell
Nuclear Transfer
(SCNT) cloning
Embryo transfer2 bull calves
10 bp
212 bp
Born April 2015
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018
POLLED
GENE
18. Purified DNA
= homozygous
polled
In vitro fertilization
(in the lab)
Frozen Semen
Semen from one of the bulls (Buri) was collected and
confirmed he was homozygous polled (PP), fertile in vitro,
and straws were frozen for artificial insemination in vivo
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018
19. 5 bull calves & 1 heifer calf were born in September, 2017
They are all hornless (heterozygous Pp for polled)
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018
20. Daughters of polled
Holstein sires will earn
less over their lifetimes
[Spurlock et al., 2014]
Polled allele frequency
is 0.0071 [Null, 2015]
Adding polled to
selection indices is not
effective [Cole, 2015]
If used exclusively
polled sires would
increase inbreeding &
decrease genetic gain
[Mueller et al., 2018]
Current polled dairy sires
have inferior genetic merit
Maci
Mueller
Van Eenennaam 6/28/2018 Animal Genomics and Biotechnology Education
[Maci Mueller et al., 2018, Unpublished]
21. Gene editing of myostatin to obtain
double muscle Nellore cattle
Van Eenennaam 6/28/2018 Animal Genomics and Biotechnology Education
Proudfoot C, Carlson DF, Huddart R, Long CR, Pryor JH, King TJ, Lillico SG,
Mileham AJ, McLaren DG, Whitelaw CB, Fahrenkrug SC. 2015. Genome edited sheep and cattle.
Transgenic Res. 24:147-53.
22. Gene editing to knockout beta-
lactoglobulin milk allergen
Van Eenennaam 6/28/2018 Animal Genomics and Biotechnology Education
Wei J, Wagner S, Maclean P, Brophy B, Cole S, Smolenski G, Carlson DF, Fahrenkrug SC, Wells
DN, Laible G. 2018. Cattle with a precise, zygote-mediated deletion safely eliminate the major milk
allergen beta-lactoglobulin. Sci Rep. 8:7661.
23. Animal Biotechnology and Genomics Education
Gene editing to produce cattle that are
less susceptible to tuberculosis
Van Eenennaam 6/28/2018
Gao et al. 2017. Single Cas9 nickase induced
generation of NRAMP1 knockin cattle with reduced
off-target effects. Genome Biol. Feb 1;18(1):13.
24. Genetic improvement (permanent,
cumulative) as a solution to animal
disease rather than antibiotics/chemicals
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018
25. Animal Biotechnology and Genomics Education
January 18th, 2017 FDA draft guidance
considers all gene edited animals whose
genomes have been “altered intentionally” to
be drugs
Van Eenennaam 6/28/2018
http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/UCM113903.pdf
Image by Aleksandra Domanović and Spencer Lowell
26. 2703 Sequenced Animals, 11x
~55 Breeds: Dairy, Beef, Dual Purpose, Crosses, Composites
1000 Bull Genomes Run 6
CRV CRV
2703 x 11 x 3 billion= 90,000,000,000,000
Slide courtesy Ben Hayes, QAAFI, Australia
Van Eenennaam 6/28/2018 Animal Biotechnology and Genomics Education
27. Run 6 – Taurus only
44.7 million filtered variants
43 million SNP, 1.7 million Indel
Run 6 – Taurus Indicus
86.5 million filtered variants
84 million SNP, 2.5 million Indel
1000 Bull Genomes Run 6
Slide courtesy Ben Hayes, QAAFI, Australia
Van Eenennaam 6/28/2018 Animal Biotechnology and Genomics Education
28. Animal Biotechnology and Genomics EducationVan Eenennaam 6/28/2018
Van Eenennaam Alison L. 2018. The Importance of a Novel Product Risk-Based Trigger for Gene-
Editing Regulation in Food Animal Species. The CRISPR Journal. 1.
https://doi.org/10.1089/crispr.2017.0023
Are Gene Edited Horn-less calves a drug?
Naturally-occurring bovine allele at Polled locus
What is the “new animal drug” in this case?
I am not a
drug
29. Animal Biotechnology and Genomics Education
Does it make sense to regulate
polled dairy calves differently to
polled beef calves?
Van Eenennaam 6/28/2018
Carroll D, Van Eenennaam AL, Taylor JF, Seger J, Voytas DF. 2016. Regulate genome-
edited products, not genome editing itself. Nat Biotech 34: 477-9 rdcu.be/hUVn
30. Van Eenennaam 6/28/2018 Animal Genomics and Biotechnology Education
May 29, 2018
Recombinetics formed an
alliance with Semex, a
Canadian-based, farmer-
owned cattle genetics
organization to
implement a precision
breeding program to
introduce hornless into
elite dairy cattle genetics
using genome editing
Canada has novel product based regulations
31. Thanks for inviting me!
My laboratory receives public funding support from the
National Institute of Food and Agriculture and the
Biotechnology Risk Assessment Grant (BRAG)
program, U.S. Department of Agriculture, under award
numbers 2013-68004-20364, 2015-67015-23316,
2015-33522-24106 and 2017-33522-27097.
Animal Genomics and Biotechnology EducationVan Eenennaam 6/28/2018