Introduction,Goals,Muscles of ventilation,Inspiration,Expiration ,Mechanics of ventilation,Lungs and pleurae,Lobes of lungs,Lung volumes and capacities,Total lung capacity,Analysis of chest shape,Barrel chest ,Pectus excavatum (funnel chest),Chest mobility,Palpation,Mediastinal shift,Auscultation of breath sounds,Normal Breath sound,Adventitious Breath sound.
Chest auscultation & lung sounds assessment for nursesMURUGESHHJ
its an brief explanation regarding respiratory system & most common sites to assess lung sounds &lobe associated lung infections...visuals explains briefly & clearly about abnormal lung conditions
Etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
Respiration, types of respiration, examination of mucous membrane, changes of color , examination of lymph-nodes, examination of skin and associated structures
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
2. Auscultation
It is the technical term for listening to the
internal sounds of the body, usually using
a stethoscope.
Auscultation is normally performed for
the purposes of examining the:
cardiovascular system and
respiratory systems (heart and lung
sounds), as well as the gastrointestinal
system (bowel sounds).
3. Auscultation of the lungs and air passages
is the most critical of the physical
examinations made of the respiratory
system.
The examination should be performed in
as quiet an environment as possible.
-though it is often difficult to achieve a
silent listening environment in large
animal practice
4. Auscultation can be done by two ways:
1. Direct by placing the ear to the body
surface over the organ.
2. Indirect auscultation by a stethoscope is
the perfect technique.
Both the upper and lower parts of the
respiratory tract must be examined in every
case to assess the rate of air flow and the
volume of air sound to be heard over the
lungs.
5. The position of examination lungs on the
animal:
1. Anterior line:
Posterior angle of scapula end in to
olecranon process of ulna.
2. Dorsal line:
Begin in posterior angle of scapula to last
space interibs (external angle of the ilium).
3. Ventral line: (mid. 9&11 or 12)
6.
7.
8.
9. Lung sounds:
Will not be heard if they are:
1-not generated (as a result of lack of
airflow in bronchi) or
2- Muffled by extensive accumulations of
fluid or fat between the lung and the
chest wall.
10. Lung sounds are reduced in:
1. animals with airflow of low velocity in
large airways.
2. When the bronchial lumen filled with
fluid or tissue.(pneumonia).
Low sound occur in case of:
Animals at rest or animals have rapid but
shallow breathing.
11. BREATH SOUNDS
Terminology used to describe normal and
abnormal lung sounds. It is a useful
diagnostic aid.
The variables that must be noticed include:
1. The nature of the sounds (increased or
decreased, crackles or wheezes)
2. The timing of the sounds in the respiratory
cycle
3. Their anatomical location
12. Breath sounds are produced by air
movement through the tracheobronchial
tree.
Normal breath sounds vary in quality
depending on where the stethoscope is
placed over the respiratory tract. They are
loudest over the trachea and base of the
lung and quietest over the diaphragmatic
lobes of the lung.
13. Normal breath sounds are louder on
inspiration than on expiration because
inspiration is active with more rapid
airflow, whereas expiration is passive in
normal animals and associated with lower
rates of airflow. Breath sounds may be
barely audible in obese animals or in the
noisy surroundings common in field
conditions.
14. 1. Vesicular sound
2. Bronchial sound
Increased loudness of breath sounds is
heard in normal animals with increased:
1.respiratory rate
2.depth of respiration.
15. This can occur for physiological reasons
such as:
1.Exercise
2. excitement
3. a high environmental temperature.
They can also occur in abnormal states such
as:
1. Fever
2. Acidosis
3. Pulmonary congestion in early pneumonia
4. Myocardial disease.
16. Decreased loudness or complete absence
of breath sounds occurs:
- in pleural effusion or
- pneumothorax
- fluids.
- Space-occupying masses between the
lung and the thoracic
17. Normal breath sounds:
1. Vesicular respiratory sound
-exaggerated
-attenuated
-muffled
2. Bronchial respiratory sound
Abnormal lung sounds:
1. Rales (Crakels, Wheeze):
-Coarse crackles are caused by air bubbling through,
and causing vibrations and secretions in large airways.
- Fine crackles are caused by sudden explosive
popping on closed airways during expiration. May be
detected in early or late inspiration.
18. Rales noticed in the following:
- exudative bronchopneumonia.
- tracheobronchitis.
- aspiration pneumonia.
- obstructive pulmonary disease.
Loud crackles:
may be audible in animals with interstitial
pulmonary emphysema
19. 2. Pleuritic friction sound:
This sound is not common .It is a combination of
continuous and discontinuous sounds produced
by the rubbing together of inflamed parietal and
visceral of pleura during the respiratory cycle.
- It is occur in cattle with severe diffuse
pulmonary emphysema
3.Miscellaneous
- unexpected sounds that are occasionally audible
over the thorax include:
-Peristaltic sounds:
20. Skin and hair sounds caused by
the stethoscope.
- Crepitating sounds due to subcutaneous
emphysema and muscular tremor.
contractions.
Crepitations in Loud superficial crackling
sounds induced by subcutaneous tissues
movement of stethoscope over the skin
Peristaltic sounds Gurgling, grating,
rumbling, squishing sounds audible over the
lungs
23. Auscultation of the heart
HEART SOUNDS
In the horse it is not common to hear for
heart sounds on auscultation,
whereas two to three heart sounds are
heard in ruminants and camelids . With
cattle, sheep, goats and swine the sound is
located at a similar level but at the fourth
intercostal space. the left fifth intercostal
space in horse:
24.
25.
26. Heart sounds are detectable by
auscultation on the left side in animals of
all condition score
27. Percussion (tapping)
The resonance of an organ can be
determined by the vibrations produced
within it by using a sharp force.
The sound produced depend on the shape,
size and density of the organ.
The sounds vary with the density of the
parts and may be classified as follows:
-Resonant:
This sound emitted by organs containing
air, e.g. normal lung
28. - Tympanic:
a drum-like note emitted by an organ
containing gas under pressure such as a
tympanic rumen or cecum.
-Dull:
This sound emitted by solid organs such
as heart and liver.
- Hyperresonant:
- In case of emphysema
29. Percussion can be performed with the
fingers using one hand as a plexor and
other as a pleximeter.
In large animals pleximeter hammer on a
pleximeter disc recommended for
consistency.
30.
31.
32.
33.
34.
35. Be aware for the thickness and consistency
of overlying tissues.
Percussion is a valuable aid in the diagnosis
of diseases of:
- The lungs
- Abdominal viscera of all large animals.
The increased of dullness over the thorax
indicates:
-Consolidation of the lung,
-A pleural effusion,
-Space-occupying lesion such as tumor or
abscess.
36. Increased resonance sound over the thorax
suggests:
- Emphysema or
- Pneumothorax.
The normal sounds in the different organs
per percussion are:
1. Percussion of the heart-
- Absolute dullness
2. Of the lung:
- Resonant in equine, cattle, goat and sheep
- Tympanic in dog and cat