Contagious bovine pleuropneumonia (CBPP) is caused by the bacterium Mycoplasma mycoides subspecies mycoides. It is highly contagious and spreads through inhalation of infected droplets. The disease is widespread in Africa and some parts of Asia and Europe. Morbidity can be up to 70% in susceptible herds with mortality around 50%. Clinical signs include fever, difficulty breathing, and fluid in the lungs. At necropsy, the lungs appear solid and adhered to the chest wall. Control methods include quarantine, testing and slaughter to eradicate the disease or vaccination with attenuated strains to limit spread where cattle movement cannot be restricted.