In anatomy, special senses are the senses that have organs specifically devoted to them such as vision, gustation, olfaction, audition, and equilibrioception. These senses have specialized organs that detect and process stimuli and send signals to the brain which lead to the perception of that stimulus.
The document describes the anatomy and physiology of the human eye. It details the structures of the eye including the fibrous layer (sclera and cornea), vascular layer (choroid, ciliary body, and iris), and sensory layer (retina containing rods and cones). It explains how light enters the eye and is refracted by the cornea, aqueous humor, lens, and vitreous humor, forming an inverted image on the retina. The ability of the lens to change shape and focus light on near and far objects through accommodation is also described. Common eye conditions like cataracts, glaucoma, and refractive errors are summarized.
Senses : any of the physical processes by which stimuli are received, transduced, and conducted as impulses to be interpreted in the brain.
The special senses consist of the eyes, ears, nose, throat and skin.
Each of these organs have specialized functions that make if possible for us to experience our environment and to make that experience more pleasant
This document provides an overview of the human senses and visual system. It discusses the general senses of touch, temperature, pressure and pain. The special senses of smell, taste, sight, hearing and balance are also covered. Most of the document focuses on the structures and functions of the eye, including the accessory structures, layers of the eye, neurons in the retina, lens accommodation, common vision conditions, and the visual pathway in the brain. Key eye structures like the cornea, iris, pupil, lens, vitreous humor and optic nerve are described.
special sense organs (anatomy and physiology) - a brief discussion Pallab Nath
brief discussion on special senses, Basic level class for technicians. topics discussed include eyes and vision, nose and sense of smell, tongue and sense of taste and ears and hearing
The document summarizes key structures and physiology of the eye. It describes the accessory structures like eyelids, lacrimal apparatus and extraocular muscles. It then details the three tunics that make up the eyeball: the fibrous tunic (sclera and cornea), vascular tunic (choroid, ciliary body and iris) and nervous tunic (retina). It explains the layers of the retina and how photoreceptors convert light to electrical signals via the ON-OFF bipolar cell mechanism. The summary provides an overview of the essential anatomy and physiology discussed in the document.
The eye is composed of three layers: the outer fibrous layer, middle vascular layer, and inner nervous tissue layer. It contains structures like the lens, aqueous fluid, and vitreous body. Light enters through the cornea and is refracted by the lens to focus on the retina. The iris and pupil regulate the amount of light entering, and accommodation and refraction allow for vision at varying distances. Dark and light adaptation involve changes in the retina and visual pigments in response to light levels. Accessory structures include extraocular muscles, eyebrows, eyelids, and the lacrimal apparatus.
The document discusses the human sensory systems. It describes the different sensory systems including vision, hearing, taste, smell, and somatic senses. It provides classifications of sensory receptors by function, location, and structure. It also provides details on specific sensory systems such as the eye, ear, and skin receptors. The eye is described in terms of its layers, internal structures, visual pathway, and role in vision. The ear is described as having three main regions for hearing and balance.
The lymphatic system consists of lymph vessels, lymph nodes, and lymphoid tissues that work together to drain excess fluid from tissues, absorb and transport fatty acids from the gut, and help fight infection. Lymph is formed when interstitial fluid drains into initial lymphatic vessels and circulates through a network of vessels, nodes, ducts, and eventually returns to the bloodstream. Lymph nodes filter lymph as it circulates and contain immune cells that help fight pathogens. The major lymphatic ducts are the thoracic duct and right lymphatic duct which drain lymph into the bloodstream in the neck.
The document describes the anatomy and physiology of the human eye. It details the structures of the eye including the fibrous layer (sclera and cornea), vascular layer (choroid, ciliary body, and iris), and sensory layer (retina containing rods and cones). It explains how light enters the eye and is refracted by the cornea, aqueous humor, lens, and vitreous humor, forming an inverted image on the retina. The ability of the lens to change shape and focus light on near and far objects through accommodation is also described. Common eye conditions like cataracts, glaucoma, and refractive errors are summarized.
Senses : any of the physical processes by which stimuli are received, transduced, and conducted as impulses to be interpreted in the brain.
The special senses consist of the eyes, ears, nose, throat and skin.
Each of these organs have specialized functions that make if possible for us to experience our environment and to make that experience more pleasant
This document provides an overview of the human senses and visual system. It discusses the general senses of touch, temperature, pressure and pain. The special senses of smell, taste, sight, hearing and balance are also covered. Most of the document focuses on the structures and functions of the eye, including the accessory structures, layers of the eye, neurons in the retina, lens accommodation, common vision conditions, and the visual pathway in the brain. Key eye structures like the cornea, iris, pupil, lens, vitreous humor and optic nerve are described.
special sense organs (anatomy and physiology) - a brief discussion Pallab Nath
brief discussion on special senses, Basic level class for technicians. topics discussed include eyes and vision, nose and sense of smell, tongue and sense of taste and ears and hearing
The document summarizes key structures and physiology of the eye. It describes the accessory structures like eyelids, lacrimal apparatus and extraocular muscles. It then details the three tunics that make up the eyeball: the fibrous tunic (sclera and cornea), vascular tunic (choroid, ciliary body and iris) and nervous tunic (retina). It explains the layers of the retina and how photoreceptors convert light to electrical signals via the ON-OFF bipolar cell mechanism. The summary provides an overview of the essential anatomy and physiology discussed in the document.
The eye is composed of three layers: the outer fibrous layer, middle vascular layer, and inner nervous tissue layer. It contains structures like the lens, aqueous fluid, and vitreous body. Light enters through the cornea and is refracted by the lens to focus on the retina. The iris and pupil regulate the amount of light entering, and accommodation and refraction allow for vision at varying distances. Dark and light adaptation involve changes in the retina and visual pigments in response to light levels. Accessory structures include extraocular muscles, eyebrows, eyelids, and the lacrimal apparatus.
The document discusses the human sensory systems. It describes the different sensory systems including vision, hearing, taste, smell, and somatic senses. It provides classifications of sensory receptors by function, location, and structure. It also provides details on specific sensory systems such as the eye, ear, and skin receptors. The eye is described in terms of its layers, internal structures, visual pathway, and role in vision. The ear is described as having three main regions for hearing and balance.
The lymphatic system consists of lymph vessels, lymph nodes, and lymphoid tissues that work together to drain excess fluid from tissues, absorb and transport fatty acids from the gut, and help fight infection. Lymph is formed when interstitial fluid drains into initial lymphatic vessels and circulates through a network of vessels, nodes, ducts, and eventually returns to the bloodstream. Lymph nodes filter lymph as it circulates and contain immune cells that help fight pathogens. The major lymphatic ducts are the thoracic duct and right lymphatic duct which drain lymph into the bloodstream in the neck.
This is about the general physiology of sense organs for medical and paramedical professional beginners who choose pharmacy, nursing and physiotherapy to study.
Anatomy and physiology of nervous systemShweta Sharma
The nervous system is made up of the central nervous system (brain and spinal cord) and the peripheral nervous system. The central nervous system contains approximately 10 million sensory neurons that send information to the brain and 500,000 motor neurons that control muscles and glands. The brain is protected by three layers of tissue called meninges and cerebrospinal fluid. The brain controls functions like sensation, memory, movement, vision, respiration, temperature regulation and more. The spinal cord transmits signals between the brain and body and contains sensory and motor neurons.
Cell is the basic unit of the body and is composed primarily of water, proteins, lipids, and carbohydrates. The cell contains membrane-bound organelles that carry out specific functions. Mitochondria produce energy through ATP production. The endoplasmic reticulum and Golgi apparatus synthesize proteins and lipids. Lysosomes digest materials through hydrolytic enzymes. Cellular waste and debris are removed through autophagy and phagocytosis. Movement of the cell is achieved through ameboid movement and cilia/flagella.
The endocrine system is made up of glands that produce and secrete hormones, chemical substances produced in the body that regulate the activity of cells or organs. These hormones regulate the body's growth, metabolism (the physical and chemical processes of the body), and sexual development and function.
The document summarizes the anatomy of the eye. It describes the layers of the eyeball including the fibrous coat with the cornea and sclera, the vascular coat with the iris, ciliary body and choroid, and the nervous coat of the retina. It also discusses the lens and segments of the eyeball. Additionally, it outlines the ocular adnexa including the bony orbit, eyelids, conjunctiva, lacrimal apparatus, extraocular muscles and accessory organs of the eye.
The lymphatic system consists of lymphatic tissues and vessels that work with the cardiovascular system to remove interstitial fluid from tissues, transport fats and lymphocytes, and provide immune defenses. Lymphatic tissues include the thymus, lymph nodes, spleen, and lymphatic nodules. Lymphatic vessels drain lymph from tissues into lymph nodes and eventually into the thoracic duct or right lymphatic duct, which empty into subclavian veins. The lymph nodes filter lymph before it returns to the bloodstream. Major groups of lymph nodes are located around joints, in the neck, chest, abdomen, and groin.
The physiology of the human eye involves several key structures working together. The eye receives light stimuli which is transformed into nerve impulses along the optic nerve to the visual cortex where it creates visual sensation. The external structures include the eyelids, conjunctiva, extraocular muscles, and bony orbit. Internally, the eye contains the iris, pupil, lens, vitreous humour, retina, aqueous humour, optic nerve and blood vessels which work to focus light, transmit signals to the brain and provide nourishment to the eye. The retina in particular contains light-sensitive rod and cone cells that convert light energy into electrical signals.
he sense organs — eyes, ears, tongue, skin, and nose — help to protect the body. The human sense organs contain receptors that relay information through sensory neurons to the appropriate places within the nervous system.
Each sense organ contains different receptors.
General receptors are found throughout the body because they are present in skin, visceral organs (visceral meaning in the abdominal cavity), muscles, and joints.
Special receptors include chemoreceptors (chemical receptors) found in the mouth and nose, photoreceptors (light receptors) found in the eyes, and mechanoreceptors found in the ears.
in this ppt we describe about anatomy of eyeball( cornea, sclera, choroid, iris, retina, ciliary body, vitreous etc..), dimension of the eyeball, coats of the eyeball.
Nervous system- SYMPATHETIC and PARASYMPATHETICKemberly Lee
The document discusses the autonomic nervous system (ANS), which regulates involuntary body functions. The ANS has two divisions - the sympathetic and parasympathetic nervous systems. The sympathetic system activates the body's fight or flight response and increases functions like heart rate. The parasympathetic system calms the body and increases functions like digestion when the body is at rest.
The document summarizes the anatomy and physiology of the human eye. It describes the layers of the eyeball (outer layer, middle layer, inner layer), structures within each layer like the iris, choroid, retina, as well as the vitreous humor and aqueous humor. It explains visual receptors (rods and cones), the process of vision including photochemistry, accommodation, errors of refraction like myopia and presbyopia. In addition, it covers topics like visual field, dark adaptation, color vision and color blindness.
structure of eye ball,eyeball is a specialized sense organ that helps us to understand our environment. It is a sensory unit composed of three parts: receptor, sensory pathway, and a brain center
The main parts of the human eye are The Conjunctiva,
Sclera,Choroid,
Cornea, Iris, Pupil,
Anterior Chamber,
Posterior Chamber, Aqueous humor, Lens, Vitreous humor, Retina,Macula and Optic nerve.
The lymphatic system works with the cardiovascular system to return fluid to the bloodstream that has escaped into tissues. Lymph is tissue fluid that is picked up by lymph capillaries from interstitial fluid and contains oxygen, proteins, glucose and white blood cells. Lymph vessels carry lymph through lymph nodes which filter the lymph before returning it to the bloodstream via the thoracic duct or right lymphatic duct. Key components of the lymphatic system include lymph nodes, tonsils, spleen and thymus which help fight infection and return fluid to circulation.
The eye is the organ of sight that contains photoreceptors called rods and cones in the retina. It has three layers - an outer fibrous layer containing the sclera and cornea, a middle vascular layer containing the iris, choroid and ciliary body, and an inner nervous layer containing the retina. The eyelids and tears protect the eyeball. The components of the eye include the sclera, cornea, iris, pupil, lens, retina, macula, optic nerve, vitreous, choroid and ciliary body.
The cardiovascular system consists of the heart, blood vessels, and blood. The heart is a hollow muscular organ located in the chest that pumps blood through two circuits: systemic circulation and pulmonary circulation. It has four chambers - right and left atria and ventricles separated by valves. Blood vessels include arteries, which carry blood away from the heart, and veins, which carry blood back to the heart. The cardiovascular system also contains a conduction system that initiates and regulates the heartbeat, starting with the sinoatrial node. Blood vessels have three layers - tunica intima, media, and externa - that vary in thickness and composition between arteries and veins.
The document discusses the anatomy and physiology of the eye and ear. It describes the structures of the eye such as the coats, lacrimal apparatus, extraocular muscles, and refractive media. Common eye disorders like styes, conjunctivitis, glaucoma and strabismus are mentioned. The parts of the ear like the pinna, external auditory meatus, tympanic membrane, middle ear ossicles, inner ear bony and membranous labyrinths are outlined. Some ear diseases including otitis externa, media, Meniere's disease, and presbycusis are briefly discussed.
The eye has three layers - an outer fibrous layer, middle vascular layer, and inner nervous tissue layer. It contains structures like the lens, aqueous and vitreous fluids, iris, pupil, retina with rods and cones, optic nerve, and extraocular muscles. The retina contains light-sensitive photoreceptors that convert light into nerve impulses which travel via the optic nerve to the brain where vision is perceived. Accessory structures like the eyelids, eyelashes, lacrimal glands, and conjunctiva help protect and lubricate the eye.
1) The document discusses the three types of muscular tissue - skeletal, cardiac, and smooth muscle.
2) Skeletal muscle is striated, voluntary muscle attached to bones. It contains bundles of fibers surrounded by connective tissue. Microscopically, it contains myofibrils with repeating dark A and light I bands.
3) Cardiac muscle is striated and involuntary. Microscopically, its branching fibers are joined end to end at intercalated discs.
4) Smooth muscle is non-striated and present in organs like blood vessels. Microscopically, its spindle-shaped cells are arranged in bundles and layers connected by gap junctions.
The document provides an overview of the nervous system, including its main functions and classifications. It describes the central nervous system (brain and spinal cord) and peripheral nervous system. It also discusses the structure and function of neurons, how impulses are transmitted, and the main regions and components of the brain and spinal cord.
The document provides an overview of the anatomy and structures of the eye and sight. It discusses the three layers that make up the walls of the eye - the outer fibrous layer, middle vascular layer, and inner nervous tissue layer. It describes key internal structures like the iris, lens, retina, as well as surrounding structures like the optic nerve, chiasma and tracts. The eye functions through a complex coordinated system to take in light, focus images, and transmit visual signals through neural pathways to the brain.
Anatomy and physilogy of eye,nose and throatDeeps Gupta
The document describes the anatomy and physiology of the eye, nose, and throat. It details the structures of the eye including the outer fibrous layer, middle vascular layer, and inner nervous tissue layer. The physiology of vision is explained including refraction of light, focusing through accommodation of the lens, convergence of the eyes, photochemical activity in the retina, and processing in the brain. Accessory structures like the lacrimal apparatus, eyelids, conjunctiva, and taste buds are also outlined.
This is about the general physiology of sense organs for medical and paramedical professional beginners who choose pharmacy, nursing and physiotherapy to study.
Anatomy and physiology of nervous systemShweta Sharma
The nervous system is made up of the central nervous system (brain and spinal cord) and the peripheral nervous system. The central nervous system contains approximately 10 million sensory neurons that send information to the brain and 500,000 motor neurons that control muscles and glands. The brain is protected by three layers of tissue called meninges and cerebrospinal fluid. The brain controls functions like sensation, memory, movement, vision, respiration, temperature regulation and more. The spinal cord transmits signals between the brain and body and contains sensory and motor neurons.
Cell is the basic unit of the body and is composed primarily of water, proteins, lipids, and carbohydrates. The cell contains membrane-bound organelles that carry out specific functions. Mitochondria produce energy through ATP production. The endoplasmic reticulum and Golgi apparatus synthesize proteins and lipids. Lysosomes digest materials through hydrolytic enzymes. Cellular waste and debris are removed through autophagy and phagocytosis. Movement of the cell is achieved through ameboid movement and cilia/flagella.
The endocrine system is made up of glands that produce and secrete hormones, chemical substances produced in the body that regulate the activity of cells or organs. These hormones regulate the body's growth, metabolism (the physical and chemical processes of the body), and sexual development and function.
The document summarizes the anatomy of the eye. It describes the layers of the eyeball including the fibrous coat with the cornea and sclera, the vascular coat with the iris, ciliary body and choroid, and the nervous coat of the retina. It also discusses the lens and segments of the eyeball. Additionally, it outlines the ocular adnexa including the bony orbit, eyelids, conjunctiva, lacrimal apparatus, extraocular muscles and accessory organs of the eye.
The lymphatic system consists of lymphatic tissues and vessels that work with the cardiovascular system to remove interstitial fluid from tissues, transport fats and lymphocytes, and provide immune defenses. Lymphatic tissues include the thymus, lymph nodes, spleen, and lymphatic nodules. Lymphatic vessels drain lymph from tissues into lymph nodes and eventually into the thoracic duct or right lymphatic duct, which empty into subclavian veins. The lymph nodes filter lymph before it returns to the bloodstream. Major groups of lymph nodes are located around joints, in the neck, chest, abdomen, and groin.
The physiology of the human eye involves several key structures working together. The eye receives light stimuli which is transformed into nerve impulses along the optic nerve to the visual cortex where it creates visual sensation. The external structures include the eyelids, conjunctiva, extraocular muscles, and bony orbit. Internally, the eye contains the iris, pupil, lens, vitreous humour, retina, aqueous humour, optic nerve and blood vessels which work to focus light, transmit signals to the brain and provide nourishment to the eye. The retina in particular contains light-sensitive rod and cone cells that convert light energy into electrical signals.
he sense organs — eyes, ears, tongue, skin, and nose — help to protect the body. The human sense organs contain receptors that relay information through sensory neurons to the appropriate places within the nervous system.
Each sense organ contains different receptors.
General receptors are found throughout the body because they are present in skin, visceral organs (visceral meaning in the abdominal cavity), muscles, and joints.
Special receptors include chemoreceptors (chemical receptors) found in the mouth and nose, photoreceptors (light receptors) found in the eyes, and mechanoreceptors found in the ears.
in this ppt we describe about anatomy of eyeball( cornea, sclera, choroid, iris, retina, ciliary body, vitreous etc..), dimension of the eyeball, coats of the eyeball.
Nervous system- SYMPATHETIC and PARASYMPATHETICKemberly Lee
The document discusses the autonomic nervous system (ANS), which regulates involuntary body functions. The ANS has two divisions - the sympathetic and parasympathetic nervous systems. The sympathetic system activates the body's fight or flight response and increases functions like heart rate. The parasympathetic system calms the body and increases functions like digestion when the body is at rest.
The document summarizes the anatomy and physiology of the human eye. It describes the layers of the eyeball (outer layer, middle layer, inner layer), structures within each layer like the iris, choroid, retina, as well as the vitreous humor and aqueous humor. It explains visual receptors (rods and cones), the process of vision including photochemistry, accommodation, errors of refraction like myopia and presbyopia. In addition, it covers topics like visual field, dark adaptation, color vision and color blindness.
structure of eye ball,eyeball is a specialized sense organ that helps us to understand our environment. It is a sensory unit composed of three parts: receptor, sensory pathway, and a brain center
The main parts of the human eye are The Conjunctiva,
Sclera,Choroid,
Cornea, Iris, Pupil,
Anterior Chamber,
Posterior Chamber, Aqueous humor, Lens, Vitreous humor, Retina,Macula and Optic nerve.
The lymphatic system works with the cardiovascular system to return fluid to the bloodstream that has escaped into tissues. Lymph is tissue fluid that is picked up by lymph capillaries from interstitial fluid and contains oxygen, proteins, glucose and white blood cells. Lymph vessels carry lymph through lymph nodes which filter the lymph before returning it to the bloodstream via the thoracic duct or right lymphatic duct. Key components of the lymphatic system include lymph nodes, tonsils, spleen and thymus which help fight infection and return fluid to circulation.
The eye is the organ of sight that contains photoreceptors called rods and cones in the retina. It has three layers - an outer fibrous layer containing the sclera and cornea, a middle vascular layer containing the iris, choroid and ciliary body, and an inner nervous layer containing the retina. The eyelids and tears protect the eyeball. The components of the eye include the sclera, cornea, iris, pupil, lens, retina, macula, optic nerve, vitreous, choroid and ciliary body.
The cardiovascular system consists of the heart, blood vessels, and blood. The heart is a hollow muscular organ located in the chest that pumps blood through two circuits: systemic circulation and pulmonary circulation. It has four chambers - right and left atria and ventricles separated by valves. Blood vessels include arteries, which carry blood away from the heart, and veins, which carry blood back to the heart. The cardiovascular system also contains a conduction system that initiates and regulates the heartbeat, starting with the sinoatrial node. Blood vessels have three layers - tunica intima, media, and externa - that vary in thickness and composition between arteries and veins.
The document discusses the anatomy and physiology of the eye and ear. It describes the structures of the eye such as the coats, lacrimal apparatus, extraocular muscles, and refractive media. Common eye disorders like styes, conjunctivitis, glaucoma and strabismus are mentioned. The parts of the ear like the pinna, external auditory meatus, tympanic membrane, middle ear ossicles, inner ear bony and membranous labyrinths are outlined. Some ear diseases including otitis externa, media, Meniere's disease, and presbycusis are briefly discussed.
The eye has three layers - an outer fibrous layer, middle vascular layer, and inner nervous tissue layer. It contains structures like the lens, aqueous and vitreous fluids, iris, pupil, retina with rods and cones, optic nerve, and extraocular muscles. The retina contains light-sensitive photoreceptors that convert light into nerve impulses which travel via the optic nerve to the brain where vision is perceived. Accessory structures like the eyelids, eyelashes, lacrimal glands, and conjunctiva help protect and lubricate the eye.
1) The document discusses the three types of muscular tissue - skeletal, cardiac, and smooth muscle.
2) Skeletal muscle is striated, voluntary muscle attached to bones. It contains bundles of fibers surrounded by connective tissue. Microscopically, it contains myofibrils with repeating dark A and light I bands.
3) Cardiac muscle is striated and involuntary. Microscopically, its branching fibers are joined end to end at intercalated discs.
4) Smooth muscle is non-striated and present in organs like blood vessels. Microscopically, its spindle-shaped cells are arranged in bundles and layers connected by gap junctions.
The document provides an overview of the nervous system, including its main functions and classifications. It describes the central nervous system (brain and spinal cord) and peripheral nervous system. It also discusses the structure and function of neurons, how impulses are transmitted, and the main regions and components of the brain and spinal cord.
The document provides an overview of the anatomy and structures of the eye and sight. It discusses the three layers that make up the walls of the eye - the outer fibrous layer, middle vascular layer, and inner nervous tissue layer. It describes key internal structures like the iris, lens, retina, as well as surrounding structures like the optic nerve, chiasma and tracts. The eye functions through a complex coordinated system to take in light, focus images, and transmit visual signals through neural pathways to the brain.
Anatomy and physilogy of eye,nose and throatDeeps Gupta
The document describes the anatomy and physiology of the eye, nose, and throat. It details the structures of the eye including the outer fibrous layer, middle vascular layer, and inner nervous tissue layer. The physiology of vision is explained including refraction of light, focusing through accommodation of the lens, convergence of the eyes, photochemical activity in the retina, and processing in the brain. Accessory structures like the lacrimal apparatus, eyelids, conjunctiva, and taste buds are also outlined.
The human eye is roughly spherical and resembles a camera. It has three layers: the outer fibrous layer containing the sclera and cornea, the middle vascular layer containing the choroid, ciliary body and iris, and the inner nervous layer containing the retina. The eye contains two chambers - the anterior chamber between the cornea and lens containing aqueous humor, and the posterior chamber between the lens and retina containing vitreous humor. Key parts include the iris, pupil, choroid, ciliary body, lens, retina and optic nerve. The eye receives nourishment from the choroid and ciliary body and sends signals to the brain via the optic nerve to provide vision.
THIS POWER POINT PRESENTATION IS TO GIVE READERS AN OVERVIEW ON THE ANATOMY AND PHYSIOLOGY OF THE EYE: STRUCTURES, FUNCTIONS OF EACH PART OF THE EYE, AS WELL AS THE PHYSIOLOGY ON HOW THE IMAGE IS CAPTURED IN THE EYE AND TRANSLATED BY THE BRAIN IN ORDER TO HAVE THE MEANINGFUL VIEW OF THE IMAGE.
The document provides information on the anatomy of the eye and drug absorption through the eye. It describes the three layers that make up the wall of the eyeball - fibrous tunic, vascular tunic, and retina. It details the external structures like eyelids, cornea, iris, and pupil. Internally, it outlines the choroid, ciliary body, lens, vitreous chamber, and retina. It explains how drugs can be absorbed through the cornea or non-corneally across the conjunctiva and sclera. Factors like precorneal constraints, corneal barrier properties, and ion transport systems influence trans corneal penetration and absorption in the eye.
The document provides information about the anatomy of the eye and drug absorption. It discusses the three layers that make up the eyeball - fibrous tunic, vascular tunic, and retina. The external structures of the eye like eyelashes, eyelids, cornea, sclera, conjunctiva, and iris are described. The internal structures such as choroid, ciliary body, lens, vitreous chamber, and retina are also summarized. Key parts of the eye involved in vision like photoreceptors, blind spot, and fovea are highlighted in less than 3 sentences.
The eye is a spherical organ that allows for vision. It has three layers - an outer fibrous coat, middle vascular coat, and inner nervous coat containing photoreceptor cells. Light enters through the cornea and is focused by the lens onto the retina. Photoreceptor cells in the retina convert light into neural signals via the optic nerve. Accessory structures like the eyelids and lacrimal system help protect and lubricate the eye. Common refractive errors that impact vision like myopia, hyperopia, and astigmatism can often be corrected using lenses.
This document provides an overview of the anatomy and structure of the sensory systems, including the eye, ear, nose, and tongue. It describes in detail:
- The three parts of the ear: outer, middle, and inner ear. The outer ear collects sounds and directs them to the middle ear, which transfers sounds to the inner ear for conversion into nerve impulses.
- The structures of the eye, including the sclera, choroid, iris, lens, retina, and extraocular muscles. The eye focuses light through the cornea and lens onto the light-sensitive retina to initiate vision.
- The nose contains olfactory receptors that detect smells and transmit signals to the brain.
Eye Anatomy and Physiology in b.pharm 1 semester and 2 semester of pharmacy education.
This slide help to more to make notes and easily read out this subject.
The human eye is like a camera that takes in light and forms an image on the retina. It has several main parts including the cornea, iris, pupil, lens, retina, and optic nerve. The cornea and lens work together to refract light and focus it onto the light-sensitive retina. The retina then converts the light into neural signals that are sent to the brain via the optic nerve. Common defects of the eye that affect vision include near-sightedness, far-sightedness, cataracts, and presbyopia. These defects can typically be corrected using lenses in glasses or contact lenses.
The eye consists of three coats - the fibrous outer coat containing the sclera and cornea, the vascular pigmented middle coat containing the choroid, ciliary body and iris, and the inner nervous coat containing the retina. The eyeball also contains refractive media - the aqueous humor in the anterior and posterior chambers, the vitreous body filling the vitreous chamber behind the lens, and the transparent biconvex lens situated between the iris and vitreous body. These structures work together to allow light to enter the eye and be focused on the retina to produce vision.
The document summarizes the key structures and functions of the human visual system. It describes the eyeball's layers including the sclera, choroid, iris, ciliary body, retina and its structures like the macula and optic disk. It explains how light enters the eye and is refracted by the cornea and lens to form an image on the retina. The roles of the retina's layers and cell types in visual transduction are outlined. Accommodation and errors of refraction are also summarized.
The eyeball has three concentric layers - an outer fibrous layer, middle vascular layer, and inner neural layer. It is surrounded by protective layers like the conjunctiva and sclera. The sclera provides the eye's shape and strength while the cornea forms its clear outer surface. Inside are the iris, ciliary body, choroid, lens, vitreous cavity, and retina. Various muscles and nerves help control functions like accommodation and visual pathway transmission to the brain. The ciliary ganglion relays parasympathetic fibers to regulate processes like pupil constriction and accommodation.
The document summarizes the anatomy and physiology of the human eye and visual system. It describes the five main parts of the eye: the outer fibrous layer containing the sclera and cornea, the middle vascular layer containing the choroid, ciliary body and iris, the inner nervous layer containing the retina, and interior structures like the lens. It also discusses the accessory structures that support vision like the extraocular muscles, eyebrows, eyelids, conjunctiva and lacrimal apparatus. The visual system converts light stimuli to nerve impulses via specialized photoreceptor cells in the retina that are transmitted to the brain via the optic nerve.
The document summarizes the anatomy of the uveal tract, including the choroid, ciliary body, and iris. It describes the layers, blood supply, innervation, and functions of each structure in detail. The choroid lines the back of the eye and contains capillaries that nourish the outer retina. The ciliary body produces aqueous humor and helps with accommodation by suspending the lens. The iris divides the eye into anterior and posterior chambers and controls the pupil size to regulate light entry.
This document summarizes the key sensory organs - eye and ear. It describes the main structures of the eye such as the eyelids, lacrimal apparatus, extraocular muscles, coats of the eyeball, light transmitting structures and the mechanism of vision. It also discusses accommodation and common eye diseases. Regarding the ear, it outlines the external, middle and internal parts, and describes structures like the tympanic membrane, ossicles and cochlea which are important for hearing. The vestibule and semicircular canals are also mentioned as parts of the inner ear involved in equilibrium.
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1 GNM anatomy Unit - 12 - sense organs.pptxthiru murugan
By:M. Thiru murugan
Unit – 12:
Skin, eye, ear, nose and tongue
Physiology of vision, hearing, smell, touch, taste and equilibrium.
Sensory organs or Special senses:
The nervous system must receive and process information about the world outside in order to react, communicate, and keep the body healthy and safe.
Skin, eye, ear, nose & tongue (taste buds) are called sensory organ or special senses.
Sensory organs have special receptors that allow us to smell, taste, see, hear, touch and maintain equilibrium or balance.
Information conveyed from these receptors to the central nervous system is used to help maintain homeostasis(self-regulating process by which biological systems help to maintain stability while adjusting to conditions that are optimal for survival).
Skin:
Skin is the largest organ of our body.
It is related to the sense of touch. The sense of touch is also referred to as tactioception.
The skin contains general receptors which can detect touch, pain, pressure & temperature.
They are present throughout the skin.
Skin receptors generate an impulse, and when activated, is carried to the spinal cord and then to the brain.
Structure of the skin:
The skin is composed of 3 major layers of tissue:
Epidermis layer
Dermis layer
Subcutaneous layer.
The epidermis, the outermost layer of skin, provides a waterproof barrier and creates our skin tone.
The dermis - the middle layer, under the epidermis, contains tough connective tissue, hair follicles, and sweat glands.
The subcutaneous tissue (hypodermis) - deeper/ innermost layer, it is made of fat and connective tissue.
Epidermis:
The epidermis is the thin, outer layer of the skin that is visible to the eye.
Contains different types of cells: keratinocytes, melanocytes, Merkel cells and Langerhans cells.
The skin’s color is created by special cells called melanocytes, which produce the pigment melanin. Melanocytes are located in the epidermis. These form a pigment shield against UV radiation.
It does not contain blood vessels
The epidermis consists of 4 layers: Stratum germinativum, Stratum spinosum, Stratum granulosum, Stratum corneum
Main functions: protection, absorption of nutrients and homeostasis.
Dermis:
The dermis is the middle layer of the skin that offers elasticity.
It is composed of connective tissues and collagen fibers.
is much thicker than the epidermis
The dermis provides a site for the hair follicles, sweat glands, sebaceous glands, blood vessels, lymph vessels, sensory receptors, nerve fibers, muscle fibers & specialized cells (mast cells and fibroblasts).
The main functions of the dermis are:
Protection
Cushioning the deeper structures from mechanical injury;
Providing nourishment to the epidermis;
Playing an important role in wound healing
Subcutaneous:
The subcutaneous is the layer of tissue directly underneath the dermis.
It is also called hypodermis.
This layer of tissue is composed of fat cells and connective tissue.
It is the thickest l
Similar to Anatomy and Physiology of Special senses (20)
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ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
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Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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BÀI TẬP BỔ TRỢ TIẾNG ANH 8 CẢ NĂM - GLOBAL SUCCESS - NĂM HỌC 2023-2024 (CÓ FI...
Anatomy and Physiology of Special senses
1. SHIMLA NURSING COLLEGE
PRESENTATION
ON
THE SPECIAL SENSES
SUBJECT: NURSING EDUCATION
SUBMITTED TO: SUBMITTED BY:
DR. PALLAVI PATHANIA MS. SHAILJA GUPT
ASSOCIATE PROFESSOR M.Sc. (N) 1ST YEAR
SHIMLA NURSING COLLEGE SHIMlA NURSING COLLEGE
2. We will discuss about……
• Sight and the eye
• Hearing and the ear
• The skin(structure ,functions)
• Sense of taste
• Sense of smell
• Balance and the ear
• Sensory receptors
• Types of sensory receptors &impulses
videos –
• inner ear balancing
• optic tracts functioning
• heamostasis and the wound healing
3. introduction
• Sensation is the physical process during which
sensory systems respond to stimuli and provide data
for perception.
4. Contd…..
• The special senses of hearing, sight, smell, taste and
touch all have specialized sensory receptors .
• They collect and transmit information to specific
areas of the brain.
6. Control centre for special senses
• The CNS including brain and the spinal cord is the
control center for special senses.
• The CNS has various centers located within it that
carry out the sensory, motor and integration of data.
•
7. Synonyms for special senses
• Also called as somatosensory system and sense
modality.
8. s.no. Special senses Anatomy of the structure Physiology of the
structure
1). Sense of sight Structure of eye Physiology of eye
2). Sense of hearing Structure of ear Physiology of hearing
3). Sense of touch Structure of skin Physiology of skin
4). Sense of taste Structure of taste buds Physiology of taste
5). Sense of smell Structure of olfactory nerves Physiology of smell
6). Sense of Balance The semicircular canals and
vestibule
Physiology of balance
Special senses includes-
11. introduction
• The eye is the organ of
sight. It is situated in the
orbital cavity and supplied
by the optic nerve (2nd
cranial nerve).
• It is almost spherical in
shape and about 2.5 cm in
diameter.
• The bony walls of the orbit
and the fat protect the eye
from injury.
13. Structure of eye
There are three layers of
tissue in the walls of the
eye:
• The outer fibrous layer:
Sclera and Cornea
• The middle vascular layer
or uveal tract: consisting
of the choroid, ciliary body
and iris
• The inner nervous tissue
layer: the retina.
15. SCLERA AND CORNEA
• The sclera, or white of the eye, forms the outermost
layer of the posterior and lateral aspects of the
eyeball and is continuous anteriorly with the cornea.
• It consists of a firm fibrous membrane that
maintains the shape of the eye and gives attachment
to the extrinsic muscles of the eye.
16. [
• Anteriorly the sclera continues as a clear transparent
epithelial membrane, the cornea.
• Light rays pass through the cornea to reach the
retina. The cornea is convex anteriorly and is involved
in refracting (bending) light rays to focus them on the
retina.
17. Choroid
• The choroid lines the
posterior five-sixths of the
inner surface of the sclera.
• It is very rich in blood
vessels and is deep
chocolate brown in colour.
• Light enters the eye
through the pupil,
stimulates the sensory
receptors in the retina and
is then absorbed by the
choroid.
18. Ciliary body
• The ciliary body is the anterior continuation of the
choroid consisting of ciliary muscle (smooth muscle
fibres) and secretory epithelial cells.
• The ciliary muscle acts like a sphincter.
19. contd…
• The lens is attached to the ciliary body by radiating
suspensory ligaments, like the spokes of a wheel.
• Contraction and relaxation of the ciliary muscle
fibres, which are attached to these ligaments, control
the size and thickness of the lens.
20. Contd….
• The epithelial cells secrete aqueous
fluid into the anterior segment of the
eye, i.e. the space between the lens
and the cornea (anterior and
posterior chambers) .
• The posterior chamber is a narrow
space behind the peripheral part of
the iris, and in front of the suspensory
ligament of the lens and the ciliary
processes.
• The posterior chamber consists of
small space directly posterior to the
iris but anterior to the lens
• The ciliary body is supplied by
parasympathetic branches of the
occulomotor nerve (3rd cranial nerve).
• Stimulation causes contraction of the
ciliary muscle and accommodation of
the eye
21. iris
• The iris is the visible coloured
ring at the front of the eye and
extends anteriorly from the
ciliary body, lying behind the
cornea and in front of the lens.
• It divides the anterior-segment
of the eye into anterior and
posterior chambers which
contain aqueous fluid secreted
by the ciliary body.
• It is a circular body composed
of pigment cells and two layers
of smooth muscle fibres, one
circular and the other radiating
In the center is an aperture
called the pupil
22. Contd….
• The iris is supplied by
parasympathetic and
sympathetic nerves.
• Parasympathetic stimulation
constricts the pupil and
sympathetic stimulation
dilates it
• The colour of the iris is
genetically determined and
depends on the number of
pigment cells present.
Albinos have no pigment
cells and people with blue
eyes have fewer than those
with brown eyes
23. Lens
• The lens is a highly elastic circular biconvex body,
lying immediately behind the pupil.
• It consists of fibres enclosed within a capsule and is
suspended from the ciliary body by the suspensory
ligament. Its thickness is controlled by the ciliary
muscle through the suspensory ligament.
24. Contd….
• The lens bends (refracts)
light rays reflected by
objects in front of the eye.
• It is the only structure in the
eye that can vary its
refractory power, which is
achieved by changing its
thickness.
• When the ciliary muscle
contracts, it moves forward,
releasing its pull on the lens,
increasing its thickness. The
nearer is the object being
viewed, the thicker the lens
becomes to allow focusing
25. Retina
• The retina is the innermost
lining of the eye .
• It is an extremely delicate
structure and well adapted
for stimulation by light rays.
• It is composed of several
layers of nerve cell bodies
and their axons, lying on a
pigmented layer of epithelial
cells.
• The light-sensitive layer
consists of sensory receptor
cells, rods and cones, which
contain photosensitive
pigments that convert light
rays into nerve impulses.
26. Contd….
• The retina lines about
three-quarters of the
eyeball and is thickest at
the back.
• It thins out anteriorly to
end just behind the ciliary
body.
• Near the center of the
posterior part is the
macula lutea, or yellow
spot .
27. Contd….
• In the centre of the yellow spot is a little depression called
the fovea centralis, consisting of only cones. Towards the
anterior part of the retina there are fewer cones than rods.
• About 0.5 cm to the nasal side of the macula lutea all the
nerve fibres of the retina converge to form the optic nerve.
28. Interior of the eye
• Both chambers contain a clear aqueous
fluid secreted into the posterior chamber
by the ciliary glands.
• It circulates in front of the lens, through
the pupil into the anterior chamber and
returns to the venous circulation through
the scleral venous sinus (canal of Schlemm)
in the angle between the iris and cornea
• The intraocular pressure remains fairly
constant between 1.3 and 2.6 kPa (10 to
20 mmHg) as production and drainage
rates of aqueous fluid are equal. An
increase in this pressure causes glaucoma .
29. Contd…
• Aqueous fluid supplies
nutrients and removes wastes
from the transparent structures
in the front of the eye that have
no blood supply, i.e. the cornea,
lens and lens capsule.
• Behind the lens and filling the
posterior segment (cavity) of
the eyeball is the vitreous body.
• This is a soft, colourless,
transparent, jelly-like substance
composed of 99% water, some
salts and mucoprotein. It
maintains sufficient intraocular
pressure to support the retina
against the choroid and prevent
the eyeball from collapsing.
30. Contd….
• The eye keeps its shape because of the intraocular
pressure exerted by the vitreous body and the
aqueous fluid.
• It remains fairly constant throughout life.
31. Optic nerves (second cranial nerves)
• The fibres of the optic nerve
originate in the retina and
they converge to form the
optic nerve about 0.5 cm to
the nasal side of the macula
lutea at the optic disc.
• The nerve pierces the
choroid and sclera to pass
backwards and medially
through the orbital cavity.
• It then passes through the
optic foramen of the
sphenoid bone, backwards
and medially to meet the
nerve from the other eye at
the optic chiasma.
32. Optic chiasma
• This is situated immediately in
front of and above the pituitary
gland, which is in the
hypophyseal fossa of the
sphenoid bone.
• In the optic chiasma the nerve
fibers of the optic nerve from
the nasal side of each retina
cross over to the opposite side.
The fibers from the temporal
side do not cross but continue
backwards on the same side.
• This crossing over provides
both cerebral hemispheres with
sensory input from each eye
33. Optic tracts
• These are the pathways of the
optic nerves, posterior to the optic
chiasma.
• Each tract consists of the nasal
fibres from the retina of one eye
and the temporal fibres from the
retina of the other.
• The optic tracts pass backwards to
synapse with nerve cells of the
lateral geniculate bodies of the
thalamus.
• From there the nerve fibers
proceed backwards and medially
as the optic radiations to
terminate in the visual area of the
cerebral cortex in the occipital
lobes of the cerebrum.
34. Contd….
• Other neurones originating
in the lateral geniculate
bodies transmit impulses
from the eyes to the
cerebellum where, together
with impulses from the
semicircular canals of the
inner ears and from the
skeletal muscles and joints,
they contribute to the
maintenance of posture and
balance.
36. Blood supply to the eye
• The eye is supplied with
arterial blood by the ciliary
arteries and the central
retinal artery. These are
branches of the ophthalmic
artery, a branch of the
internal carotid artery.
• Venous drainage is by a
number of veins, including
the central retinal vein,
which eventually empty into
a deep venous sinus.
• The central retinal artery and
vein are encased in the optic
nerve, which enters the eye
at the optic disc
41. Hearing and the ear
• The ear is the organ of
hearing and is also involved
in balance.
• It is supplied by the 8th
cranial nerve, i.e. the
cochlear part of the
vestibulo-cochlear nerve,
which is stimulated by
vibrations caused by sound
waves.
• Except auricle (pinna), other
structures are encased in the
petrous portion of the
temporal bone.
42.
43. Contd…..
The ear is divided into three
distinct parts:-
The outer ear,
Middle ear (tympanic cavity)
Inner ear
• The outer ear collects the
sound waves and directs
them to the middle ear.
• Middle ear in turn transfers
them to the inner ear.
• The inner ear, where they are
converted into nerve
impulses and transmitted to
the hearing area in the
cerebral cortex.
44. Contd…
Outer ear
• Auricle (pinna)
• External acoustic meatus (auditory
canal)
The auricle (pinna)
• visible part ,projects from the side of
the head.
• It is composed of fibro-elastic cartilage
covered with skin.
• Deeply grooved and ridged; the most
prominent outer ridge is the helix.
• The lobule (earlobe) -soft pliable part at
the lower extremity, composed of
fibrous and adipose tissue richly
supplied with blood
45. External acoustic meatus (auditory -
canal)
• This is a slightly ‘S’-shaped tube
about 2.5 cm long extending
from the auricle to the
tympanic membrane (eardrum).
• The lateral third is embedded in
cartilage and the remainder lies
within the temporal bone.
• The meatus is lined with skin
continuous with that of the
auricle.
46. Contd….
• There are numerous ceruminous
glands and hair follicles, with
associated sebaceous glands, in
the skin of the lateral third.
• Ceruminous glands are modified
sweat glands that secrete
cerumen (earwax), a sticky
material containing protective
substances including the
bacteriocidal enzymelysozyme
and immunoglobulins.
47. Contd…..
• The tympanic membrane
(eardrum) completely separates
the external acoustic meatus
from the middle ear. It is oval-
shaped with the slightly
broader edge upwards and is
formed by three types of tissue:
• The outer covering of hairless
skin,
• The middle layer of fibrous
Tissue
• The inner lining of mucous
membrane continuous with
that of the middle ear
48. Middle ear (tympanic cavity)
• This is an irregular-shaped
air-filled cavity within the
petrous portion of the
temporal bone
• The cavity is lined with either
simple squamous or cuboidal
epithelium.
• The lateral wall of the middle
ear is formed by the
tympanic membrane.
• The roof and floor are
formed by the temporal
bone.
49. Contd….
• The posterior wall is formed by the temporal bone
with openings leading to the mastoid antrum
through which air passes to the air cells within the
mastoid process.
51. Contd…
• The oval window is occluded by part of a small bone
called the stapes .
• The round window, by a fine sheet of fibrous tissue.
52. Pharango-tympanic membrane
• Air reaches the cavity through the pharyngo-
tympanic (auditory or Eustachian) tube, which links
the naso-pharynx and the middle ear.
53. Contd,,,.
• It is about 4 cm long and lined with ciliated columnar
epithelium.
• The presence of air at atmospheric pressure on both
sides of the tympanic membrane is maintained by
the pharyngo-tympanic tube and enables the
membrane to vibrate when sound waves strike it.
54. Contd…..
• The pharyngo-tympanic tube is normally closed but
when there is unequal pressure across the tympanic
membrane, e.g. at high altitude, it is opened by
swallowing or yawning and the ears ‘pop’, equalising
the pressure again.
55. Auditory ossicles of middle ear
• These are three very small
bones, only a few milli-
metres in size that extends
across the middle ear from
the tympanic membrane to
the oval window
The malleus.-
• This is the lateral hammer-
shaped bone.
• The handle is in contact with
the tympanic membrane
• The head forms a movable
joint with the incus.
56. Contd…
The incus.-
• This is the middle anvil-shaped bone.
• Its body articulates with the malleus, the long
process with the stapes, and it is stabilised by the
short process, fixed by fibrous tissue to the posterior
wall of the tympanic cavity.
57. Contd….
The stapes.-
• This is the medial stirrup-shaped bone.
• Its head articulates with the incus and its footplate
fits into the oval window
58. Inner ear
The inner ear or labyrinth
(meaning ‘maze’) contains
the organs of hearing and
balance.
It is described in two
parts,
• The bony labyrinth
• The membranous labyrinth
60. Contd…..
• The bony labyrinth is lined with periosteum.
• Within the bony labyrinth, the membranous
labyrinth is suspended in a watery fluid called
perilymph.
• The membranous labyrinth is filled with endolymph.
61. Contd…..
The vestibule
• This is the expanded part
nearest the middle ear.
• The oval and round
windows are located in its
lateral wall.
It contains-
• Two membranous sacs,
the utricle and the
saccule, which are
important in balance
63. Contd….
The semicircular canals
• These are three tubes arranged so that one is
situated in each of the three planes of space. They
are continuous with the vestibule and are also
important in balance
64. Membraneous labyrinth
• It contains endolymph and lies with in the bony
labyrinth.
It contains-
• The vestibule,containing utricle and saccule.
• The cochlea.
• Three semicircular canals.
65. The cochlea
• This resembles a snail’s shell. It has a broad base
where it is continuous with the vestibule and a
narrow apex, and it spirals round a central bony
column.
A cross-section of the cochlea contains three
compartments:
• The scala vestibuli
• The scala media, or cochlear duct
• The scala tympani.
66. Contd….
The bony cochlea has two compartments containing
perilymph:
• The scala vestibuli, which originates at the oval
window
• The scala tympani, which ends at the round window.
67. CONTD……
The cochlear duct is a part of the
membranous labyrinth and is
triangular in shape. On the basilar
membrane, or base of the
triangle, are
• Supporting cells and
specialised cochlear hair cells
containing auditory receptors.
• These cells form the spiral
organ (of Corti), the sensory
organ that responds to
vibration by initiating nerve
impulses that are then
perceived as hearing within
the brain.
68. Auditory Receptors..
• The auditory receptors are dendrites of efferent
(sensory) nerves that combine forming the cochlear
(auditory) part of the vestibulo-cochlear nerve (8th
cranial nerve), which passes through a foramen in
the temporal bone to reach the hearing area in the
temporal lobe of the cerebrum
73. Introduction
• The skin completely covers the body and is continuous with
the membranes lining the body orifices.
It mainly:-
• Protects the underlying structures from injury and from
invasion by microbes
• Contains sensory nerve endings that enable discrimination of
pain, temperature and touch.
• It is involved in the regulation of body temperature
74. Structure of the skin
• The skin is the largest organ in the body and has a surface
area of about 1.5–2 m2 in adults. In certain areas,
it contains:-
• Accessory structures: glands, hair and nails.
75. CONTD….
• There are two main layers:-
• The epidermis, which covers the dermis .
• The subcutaneous layer-consist of areolar and adipose tissue
between the skin and underlying structures
76. Epidermis
• This is the most superficial layer
and is composed of stratified
keratinised squamous
epithelium.
• It varies in thickness, being
thickest on the palms of the
hands and soles of the feet.
• There are no blood vessels or
nerve endings in the epidermis,
but its deeper layers are bathed
in interstitial fluid from the
dermis, which provides oxygen
and nutrients, and drains away
as lymph.
77. CONTD……
• There are several layers
(strata) of cells in the
epidermis which extend
from the deepest
germinative layer to the
most superficial stratum
corneum (a thick horny
layer)
• Epidermal cells originate in
the germinative layer and
undergo gradual change as
they progress towards the
skin surface.
78. Contd…..
• The cells on the surface are flat, thin, non-nucleated,
dead cells, or squames, in which the cytoplasm has
been replaced by the fibrous protein keratin.
• The surface cells are constantly rubbed off and
replaced by those beneath. Complete replacement of
the epidermis takes about a month
79. CONTD….
• Healthy epidermis depends
upon three processes being
synchronised:
• Desquamation (shedding) of
the keratinised cells from the
surface
• Effective keratinisation of cells
approaching the surface
• Continual cell division in the
deeper layers with newly
formed cells being pushed
upwards to the surface.
• Hairs, secretions from
sebaceous glands and ducts of
sweat glands pass through the
epidermis to reach the surface.
80. Contd…..
• Upward projections of the dermal layer, the dermal
papillae anchor this securely to the more superficial
epidermis and allow passage and exchange of
nutrients and wastes to the lower part of the
epidermis.
81. Contd…..
• This arrangement
stabilises the two layers
preventing damage due to
shearing forces.
• Blisters develop when
trauma causes separation
of the dermis and
epidermis, and serous
fluid collects between the
two layers.
• ,
82. Contd…
• In areas where the skin is
subject to greater wear and
tear, e.g. the palms and fingers
of the hands and soles of the
feet the epidermis is thicker
and hairs are absent.
• In these areas the dermal
papillae are arranged in
parallel lines giving the skin
surface a ridged appearance.
The pattern of ridges on the
fingertips is unique to every
individual and the impression
made by them is the
‘fingerprint
83. Colour of skin
• Skin colour is affected by various factors.
• Melanin, a dark pigment derived from the amino acid
tyrosine and secreted by melanocytes in the deep germinative
layer, is absorbed by surrounding epithelial cells.
• The amount is genetically determine and varies between
different parts of the body,
84. Contd….
• Between people of the same ethnic
origin and between ethnic groups.
• The number of melanocytes is fairly
constant so the differences in colour
depend on the amount of melanin
secreted.
• It protects the skin from the harmful
effects of ultraviolet rays in sunlight.
• Exposure to sunlight promotes
synthesis of melanin.
• Normal saturation of haemoglobin
and the amount of blood circulating in
the dermis give white skin its pink
colour.
• When oxygen saturation is very low,
the skin may appear bluish (cyanosis).
• Excessive levels of bile pigments in
blood and carotenes in subcutaneous
fat give the skin a yellowish colour
85. Dermis
• The dermis is tough and elastic.
• It is formed from connective tissue and the matrix contains
collagen fibres interlaced with elastic fibres.
• Rupture of elastic fibres occurs when the skin is
overstretched, resulting in permanent striae, or stretch marks,
that may be found in pregnancy and obesity.
86. Contd….
• Collagen fibres bind water and give the skin its tensile strength, but as this
ability declines with age, wrinkles develop. Fibroblasts macrophages and
mast cells are the main cells found in the dermis.
87. Contd….
• Underlying its deepest layer
is the subcutaneous layer
containing areolar tissue
and varying amounts of :-
• adipose (fat) tissue
• blood and lymph vessels
• sensory nerve endings
• sweat glands and their
ducts
• hairs, arrector pili muscles
and sebaceous glands.
88. Blood and lymph vessels of skin.
• Arterioles form a fine network with capillary branches
supplying sweat glands, sebaceous glands, hair follicles and
the dermis.
• Lymph vessels form a network throughout the dermis.
89. Sensory nerve endings
• Sensory receptors (specialised nerve endings) sensitive to
touch, temperature, pressure and pain are widely distributed
in the dermis.
• Incoming stimuli activate different types of sensory receptors
for example, the Pacinian corpuscle is sensitive to deep
pressure .
90. Contd…..
• The skin is an important sensory organ through which
individuals receive information about their environment.
Nerve impulses, generated in the sensory receptors in the
dermis, are transmitted to the spinal cord by sensory nerves .
• From there impulses are conducted to the sensory area of the
cerebrum where the sensations are perceived.
91. Sweat glands
• These are widely distributed throughout the skin and are most
numerous in the palms of the hands, soles of the feet, axillae
and groins.
• They are formed from epithelial cells.
• The bodies of the glands lie coiled in the subcutaneous tissue.
93. Contd….
• Eccrine glands are the more common type and open onto the
skin surface through tiny pores, and the sweat produced here
is a clear, watery fluid important in regulating body
temperature.
94. Contd….
• Apocrine glands open into hair follicles and become active at
puberty. They may play a role in sexual arousal. These glands
are found, for example, in the axilla. Bacterial decomposition
of their secretions causes an unpleasant odour. A specialised
example of this type of gland is the ceruminous gland of the
outer ear.
• which secretes earwax
95. Functions of sweat gland
• The most important function of sweat is in the regulation of
body temperature .
• Excessive sweating may lead to dehydration and serious
depletion of sodium chloride unless intake of water and salt is
appropriately increased.
• After 7–10 days’ exposure to high environmental
temperatures the amount of salt lost is substantially reduced
but water loss remains high.
96. Hairs
• These grow from hair follicles, down
growths of epidermal cells into the
dermis or subcutaneous tissue. At the
base of the follicle is a cluster of cells
called the hair papilla or bulb. The
hair is formed by multiplication of
cells of the bulb and as they are
pushed upwards, away from their
source of nutrition, the cells die and
become keratinised.
• The part of the hair above the skin is
the shaft and the remainder, the root .
• Hair colour is genetically determined
and depends on the amount and type
of melanin present.
• White hair is the result of the
replacement of melanin by tiny air
bubbles.
97. Arrector pili
• These are little bundles of
smooth muscle fibres attached
to the hair follicles.
• Contraction makes the hair
stand erect and raises the skin
around the hair, causing ‘goose
flesh’.
• The muscles are stimulated by
sympathetic nerve fibres in
response to fear and cold.
• Erect hairs trap air, which acts
as an insulating layer. This is an
efficient warming mechanism,
especially when accompanied
by shivering, i.e. involuntary
contraction of skeletal muscles.
98. Sebaceous glands
• These consist of secretory epithelial cells derived from the
same tissue as the hair follicles.
• They secrete an oily antimicrobial substance, sebum, into the
hair follicles and are present in the skin of all parts of the body
except the palms of the hands and the soles of the feet.
• They are most numerous in the scalp, face, axillae and groins.
99. Contd…
• In regions of transition from one type
of superficial epithelium to another,
such as lips, eyelids, nipple, labia
minora and glans penis, there are
sebaceous glands that are
independent of hair follicles,
secreting sebum directly onto the
surface.
• Sebum keeps the hair soft and pliable
and gives it a shiny appearance. On
the skin it provides some
waterproofing and acts as a
bactericidal and fungicidal agent,
preventing infection. It also prevents
drying and cracking of skin, especially
on exposure to heat and sunlight.
• The activity of these glands increases
at puberty and is less at the extremes
of age, rendering the skin of infants
and older adults prone to the effects
of excessive moisture
100. Nails
• Human nails are equivalent to the claws, horns and
hooves of animals.
• Derived from the same cells as epidermis and hair
these are hard, horny keratin plates that protect the
tips of the fingers and toes
101. Contd…
• The root of the nail is
embedded in the skin and
covered by the cuticle, which
forms the hemispherical pale
area called the lunula.
• The nail plate is the exposed
part that has grown out from
the nail bed, the germinative
zone of the epidermis.
• Finger nails grow more
quickly than toe nails and
growth is faster when the
environmental temperature
is high.
103. recaptulization
• What are the different layers of skin?
• Which is the largest organ of body?
• What are the functions of skin?
• What is the function of sebaceous glands?
106. Introduction ….
• The sense of taste, or gustation, is closely linked to
the sense of smell and, like smell, also involves
stimulation of chemoreceptors by dissolved
chemicals.
107. Contd…
• Taste buds contain chemoreceptors (sensory
receptors) that are found in the papillae of the
tongue and widely distributed in the epithelia of the
tongue. They consist of small sensory nerve endings
of the glossopharyngeal, facial and vagus nerves
(cranial nerves VII, IX and X).
108. Contd…..
• Some of the cells have hair-like cilia on their free
border, projecting towards tiny pores in the
epithelium
• The sensory receptors are highly sensitive and
stimulated by very small amounts of chemicals that
enter the pores dissolved in saliva.
110. introduction…
Olfactory nerves (first cranial nerves)
• These are the sensory nerves of smell.
• They originate as chemoreceptors (specialised
olfactory nerve endings) in the mucous membrane of
the roof of the nasal cavity above the superior nasal
conchae
111. Contd….
• On each side of the nasal
septum nerve fibers pass
through the cribriform plate of
the ethmoid bone to the
olfactory bulb where
interconnections and synapses
occur .
• From the bulb,bundles of
nerve fibres form the olfactory
tract, which passes backwards
to the olfactory area in the
temporal lobe of the cerebral
cortex in each hemisphere
where the impulses are
interpreted and odour
perceived.
112. SENSE OF BALANCE
The semicircular canals
and vestibule
• The semicircular canals
have no auditory
function although they
are closely associated
with the cochlea,
utricle, saccule and
ampullae.
113. CONTD….
• There are three semicircular
canals one lying in each of
the three planes of space
,situated above ,beside and
behind the vestibule of the
inner ear and opens into it.
• The semicircular canals, like
the cochlea, are composed
of an outer bony wall and
inner membranous tubes or
ducts.
• The membranous ducts
contain endolymph and are
separated from the bony
wall by perilymph.
114. Contd…..
• The utricle is a membranous sac which is part of the
vestibule and the three membranous ducts open into
it at their dilated ends, the ampullae. The saccule is a
part of the vestibule and communicates with the
utricle and the cochlea.
115. Contd….
• In the walls of the utricle, saccule and ampullae are
fine, specialised epithelial cells with minute
projections, called hair cells.
• Amongst the hair cells there are receptors on
sensory nerve endings, which combine forming the
vestibulocochlear nerve
119. Physiology of sight
• Light waves travel at a speed of 300 000 kilometres
(186 000 miles) per second.
• Light is reflected into the eyes by objects within the
field of vision.
• White light is a combination of all the colours of the
visual spectrum (rainbow), i.e. red, orange, yellow,
green, blue, indigo and violet.
120. Contd…
• This is demonstrated by passing white light through a glass
prism which bends the rays of the different colours to a
greater or lesser extent, depending on their wavelengths
• Red light has the longest wavelength and violet the shortest.
• This range of colour is the spectrum of visible light. In a
rainbow, white light from the sun is broken up by raindrops,
which act as prisms and reflectors
121. Contd….
• A specific colour is perceived when only one
wavelength is reflected by the object and all the others
are absorbed, e.g. an object appears red when it only
reflects red light.
• Objects appear white when all wavelengths are
reflected, and black when they are all absorbed.
122. Contd…..
• In order to achieve clear vision,
light reflected from objects
within the visual field is
focused on to the retina of
each eye.
• The processes involved in
producing a clear image are
refraction of the light rays,
changing the size of the pupils
and accommodation
(adjustment of the lens for
near vision
• Although these may be
considered as separate
processes, effective vision is
dependent upon their
coordination
123. Refraction of the light rays
• When light rays pass from a medium of one density to a
medium of a different density they are bent; for example, a
glass prism
• In the eye, the biconvex lens bends and focuses light rays .This
principle is used to focus light on the retina. Before reaching
the retina, light rays pass successively through the
conjunctiva, cornea, aqueous fluid, lens and vitreous body.
• They are all denser than air and, with the exception of the
lens, they have a constant refractory power, similar to that of
water.
124. Focusing of an image on the retina
• Light rays reflected from an object are bent
(refracted) by the lens when they enter the eye in the
same way, although the image on the retina is
actually upside down .The brain adapts to this early
in life so that objects are perceived ‘the right way up’.
• Abnormal refraction within the eye is corrected using
biconvex or biconcave lenses.
125. Lens
• The lens is a biconvex elastic transparent body
• It is suspended behind the iris from the ciliary body
by the suspensory ligament It is the only structure in
the eye able change its refractive power.
126. Contd….
• Light rays entering the eye need to be refracted to
focus them on the retina.
• Light from distant objects needs least refraction and,
as the object comes closer, the amount of refraction
needed increases.
127. Contd…..
• To focus light rays from near objects on the retina, the
refractory power of the lens must be increased – by
accommodation.
• To do this, the ciliary muscle (a sphincter) contracts moving
the ciliary body inwards towards the lens.
• This lessens the pull on the suspensory ligaments and allows
the lens to bulge, increasing its convexity and focusing light
rays on the retina
128. Contd…
• To focus light rays from distant objects on the retina,
the ciliary muscle relaxes, increasing its pull on the
suspensory ligaments. This makes the lens thinner
and focuses light rays from distant objects on the
retina.
129. Size of the pupils
• Pupil size contributes to clear vision by controlling
the amount of light entering the eye. In bright light
the pupils are constricted. In dim light they are
dilated.
130. Contd…..
The iris consists of one layer of
circular and one of radiating
smooth muscle fibres.
Contraction of the circular
fibres constricts the pupil, and
contraction of the radiating
fibres dilates it.
The size of the pupil is
controlled by the autonomic
nervous system; sympathetic
stimulation dilates the pupils
and parasympathetic
stimulation constricts them
131. Accommodation
Near vision
• In order to focus on near objects, i.e. within about 6 metres,
accommodation is required and the eye must make the
following adjustments:
• constriction of the pupils
• convergence
• changing the refractory power of the lens.
132. • Distant vision
• Objects more than 6 metres away from the eyes are
focused on the retina without adjustment of the lens
or convergence of the eyes.
133. Functions of the Retina
• The retina is the light-sensitive (photosensitive) part
of the eye. The light-sensitive nerve cells are the rods
and cones and their distribution in the retina .
• Light rays cause chemical changes in light sensitive
pigments in these cells and they generate nerve
impulses which are conducted to the occipital lobes
of the cerebrum via the optic nerves.
134. CONTD….
• The rods are much more light
sensitive than the cones so they
are used when light levels are low.
• Stimulation of rods leads to
monochromic (black and white)
vision.
• Rods outnumber cones in the
retina by about 16 : 1 and are
more numerous towards the
periphery of the retina.
• Visual purple (rhodopsin) is a light-
sensitive pigment present only in
the rods.
• It is bleached (degraded) by bright
light and is quickly regenerated,
provided an adequate supply of
vitamin A is available.
135. Contd…
• The cones are sensitive to
light and colour; bright
light is required to
activate them and give
sharp, clear colour vision.
• The different wavelengths
of visible light
lightsensitive pigments in
the cones, resulting in the
perception of different
colours
138. assignment
• Explain about physiology of light
• What are olfactory nerves?
• Discuss about sense of taste.
139. Colour blindness
This is a common condition that affects more men than
women.
There are different forms but the most common is red–
green colour blindness which is transmitted a by sex-
linked recessive gene where greens, oranges, pale reds
and browns all appear to be the same colour and can
only be distinguished by their intensity
140. Dark adaptation…
• When exposed to bright light, the rhodopsin within the
sensitive rods is completely degraded.
• This does not affect vision in good light, when there is
enough light to activate the cones.
• However, moving into a darkened area where the light
intensity is insufficient to stimulate the cones causes
temporary visual impairment whilst the rhodopsin is
being regenerated within the rods, ‘dark adaptation’.
• When regeneration of rhodopsin has occurred, normal
sight returns.
141. Binocular vision
• Binocular or stereoscopic
vision enables three-
dimensional views although
each eye ‘sees’ a scene from
a slightly different angle .
The visual fields overlap in
the middle but the left eye
sees more on the left than
can be seen by the other
eye and vice versa.
• The images from the two
eyes are fused in the
cerebrum so that only one
image is perceived
142. contd…..
• Binocular vision provides a much more accurate
assessment of one object relative to another, e.g. its
distance, depth, height and width.
• People with monocular vision may find it difficult,
for example, to judge the speed and distance of an
approaching vehicle.
143. Extraocular muscles of the eye
• The eyeball is moved by six extrinsic muscles,
• There are four straight (rectus) muscles
• Two oblique muscles.
• Movements of the eyes resulting from the action of
these muscles.
144. Accessory organs of the eye
• The eye is a delicate organ which is protected by
several structures:
• Eyebrows
• Eyelids and eyelashes
• Lacrimal apparatus
145. Eyebrows
• These are two arched ridges of the supraorbital
margins of the frontal bone. Numerous hairs
(eyebrows) project obliquely from the surface of the
skin. They protect the eyeball from sweat, dust and
other foreign bodies.
146. Eyelids (palpebrae)
• The eyelids are two movable
folds of tissue situated
above and below the front
of each eye. On their free
edges are short curved hairs,
the eyelashes. The layers of
tissue forming the eyelids
are:
• a thin covering of skin
• a thin sheet of
subcutaneous connective
(loose areolar) tissue
• two muscles – the
orbicularis oculi and levator
palpebrae superioris
147. Conjunctiva
• This is a fine transparent
membrane that lines the eyelids
and the front of the eyeball .
• Where it lines the eyelids it
consists of highly vascular
columnar epithelium.
• Corneal conjunctiva consists of
avascular stratified epithelium,
• It protects the delicate cornea and
the front of the eye.
• The medial and lateral angles of
the eye where the upper and
lower lids come together are
called respectively the medial
canthus and the lateral canthus.
148. Tarsal glands
• Tarsal glands are modified
sebaceous glands
embedded in the tarsal
plates with ducts that open
on to the inside of the free
margins of the eyelids.
• They secrete an oily
material, spread over the
conjunctiva by blinking,
which delays evaporation
of tears.
149. Contd…..
• blinking at about 3- to 7-second intervals spreads
tears and oily secretions over the cornea, preventing
drying
• When the orbicularis oculi contract, the eyes close.
When the levator palpebrae contract, the eyelids
open
150. Lacrimal apparatus
For each eye this consists of the structures that secrete tears and
drain them from the front of the eyeball:
• • 1 lacrimal gland and its ducts
• • 2 lacrimal canaliculi
• • 1 lacrimal sac
• • 1 nasolacrimal duct.
151. Contd..
• The lacrimal glands are
exocrine glands situated in
recesses in the frontal bones
on the lateral aspect of each
eye just behind the
supraorbital margin.
• Each gland is approximately
the size and shape of an
almond, and is composed of
secretory epithelial cells.
• The glands secrete tears
composed of water, mineral
salts, antibodies (immuno-
globulins) and lysozyme, a
bactericidal enzyme.
152. Contd….
• The tears leave the lacrimal
gland by several small ducts
and pass over the front of
the eye under the lids
towards the medial canthus
where they drain into the
two lacrimal canaliculi; the
opening of each is called
the punctum
• . The two canaliculi lie one
above the other, separated
by a small red body, the
caruncle.
153. Contd….
• The tears then drain into the
lacrimal sac, which is the upper
expanded end of the naso-lacrimal
duct.
• This is a membranous canal
approximately 2 cm long,
extending from the lower part of
the lacrimal sac to the nasal cavity,
opening at the level of the inferior
concha.
• . When a foreign body or other
irritant enters the eye the
secretion of tears is greatly
increased and the conjunctival
blood vessels dilate. Secretion of
tears is also increased in emotional
states, e.g. crying, laughing.
154. Functions of lacrimal apparatus
The functions of this fluid include:
• Provision of oxygen and nutrients to the avascular corneal
conjunctiva and drainage of wastes
• Washing away irritating materials, e.g. dust, grit
• The bactericidal enzyme lysozyme prevents microbial
infection
• Its oiliness delays evaporation and prevents friction or drying
of the conjunctiva.
155. Physiology of hearing…..
• Every sound produces sound waves or vibrations in the air,
which travel at about 332 meters per second.
• The auricle, because of its shape, collects and
concentrates the waves and directs them along the
auditory canal causing the tympanic membrane to vibrate.
156. CONTD….
• Tympanic membrane vibrations are transmitted and
amplified through the middle ear by movement of the
ossicles.
• At their medial end the footplate of the stapes rocks to and
fro in the oval window, setting up fluid waves in the
perilymph of the scala vestibuli.
157. CONTD…
• The volume depends on the magnitude of the sound
waves and is measured in decibels (dB).
• The greater the amplitude of the wave created in the
endolymph, the greater is the stimulation of the
auditory receptors in the hair cells in the spiral organ,
enabling perception of volume.
• Long-term exposure to excessive noise causes
hearing loss because it damages the sensitive hair
cells of the spiral organ.
158. Functions of eyelids and eyelashes
• The eyelids and eyelashes
protect the eye from
injury:
• reflex closure of the lids
occurs when the
conjunctiva or eyelashes
are touched, when an
object comes close to the
eye or when a bright light
shines into the eye –
• this is called the corneal
reflex
• .
159. Physiology &functions of the skin
Protection
• The skin forms a relatively
waterproof layer, provided
mainly by its keratinised
epithelium, which protects
the deeper, more delicate
structures. As an important
nonspecific defence
mechanism it acts as a
barrier against:
• invasion by micro-organisms
• chemicals
• physical agents, e.g. mild
trauma, ultraviolet light
• dehydration.
160. Contd…
• The epidermis contains specialised
immune cells called dendritic
(Langerhans) cells, which are a type
of macrophage.
• They phagocytose intruding antigens
and travel to lymphoid tissue, where
they present antigen to T-
lymphocytes, thus stimulating an
immune response
• Abundant sensory nerve endings in
the dermis enable perception,
discrimination and location of
internal and external stimuli.
• This allows responses to changes in
the environment, e.g. by reflex action
(withdrawal) to unpleasant or painful
stimuli, protecting it from further
injury.
• Melanin protection.
161. Contd….
Regulation of body temperature
• Body temperature remains fairly constant around 36.8°C
across a wide range of environmental temperatures ensuring
that the optimal range for enzyme activity required for
metabolism is maintained.
162. Contd….
• In health variations are usually limited to between 0.5 and
0.75°C, although it rises slightly in the evening, during exercise
and in women just after ovulation.
• To maintain this constant temperature, a negative feedback
system regulates the balance between heat produced in the
body and heat lost to the environment.
163. Contd…
Heat production
• When metabolic rate increases, body temperature rises,and
when it decreases body temperature falls. Some of the energy
released during metabolic activity is in the form of heat; the
most active organs produce most heat.
164. Contd….
• The principal organs involved
are:
• skeletal muscles – contraction
of skeletal muscles produces a
large amount of heat and the
more strenuous the muscular
exercise, the greater the heat
produced.
• Shivering also involves skeletal
muscle contraction, which
increases heat production
when there is the risk of body
temperature falling below
normal.
165. Contd…
• the liver is very
metabolically active,
which produces heat as a
by-product.
• Metabolic rate and heat
production are increased
after eating.
• the digestive organs that
generate heat during
peristalsis and the
chemical reactions
involved in digestion
166. Heat loss
• Most heat loss from the
body occurs through the
skin.
• Small amounts are lost in
expired air, urine and faeces.
• Only heat loss through the
skin can be regulated; heat
lost by the other routes
cannot be controlled.
• Heat loss through the skin is
affected by the difference
between body and
environmental temperatures
167. Contd…
• The amount of the body
surface exposed and the type
of clothes worn.
• Air insulates against heat loss
when trapped in layers of
clothing and between the skin
and clothing.
• For this reason several layers
of lightweight clothes provide
more effective insulation
against low environmental
temperatures than one heavy
garment.
168. Mechanisms of heat loss
• In radiation, the main mechanism,
exposed parts of the body radiate
heat away from the body.
• In evaporation, the body is cooled
as body heat converts the water in
sweat to water vapour.
• In conduction, clothes and other
objects in direct contact with the
skin take up heat.
• In convection, air passing over the
exposed parts of the body is
heated and rises, cool air replaces
it and convection currents are set
up.
• Convection also cools the body
when clothes are worn, except
when they are windproof.
174. Formation of vitamin D
• 7-Dehydrocholesterol is a lipid-based substance in
the skin and is converted to vitamin D by sunlight.
• This vitamin is used with calcium and phosphate in
the formation and maintenance of bone.
176. recaptulization
• What is binocular vision
• Explain the functions of skin
• How many extraocular muscles are there
• What is colour blindness
177. Assignment-5
• Define physiology of hearing
• Define mechanism of contorl of body temperature
• Explain about the structure of eye in detail
• Discuss about the structure of ear in detail
• Discuss the function of skin
179. Absorption
• This property is limited but substances that can be absorbed
include:
• some drugs, in transdermal patches, e.g. hormone
replacement therapy during the menopause, nicotine as an
aid to smoking cessation
• some toxic chemicals, e.g. mercury.
183. Primary healing (healing by first
intention)
• This type of healing follows minimal
destruction of tissue when the
damaged edges of a wound are in
close apposition, e.g. a surgical incision
• There are several overlapping stages in
the repair process.
• Inflammation. In the first few hours
the cut surfaces become inflamed and
blood clot and cell debris fill the gap
between them. Phagocytes, including
macrophages, and fibroblasts migrate
into the blood clot:
• phagocytes begin to remove the clot
and cell debris, stimulating fibroblast
activity
• fibroblasts secrete collagen fibres which
begin to bind the wound margins
together.
184. Proliferation
• Epithelial cells proliferate across
the wound, through the clot.
The epidermis meets and grows
upwards until full thickness is
restored.
• The clot above the new tissue
becomes the scab, which
separates after 3–10 days.
• Granulation tissue, consisting of
new capillary buds, phagocytes
and fibroblasts, develops,
invading the clot and restoring
blood supply to the wound.
• Fibroblasts continue to secrete
collagen fibres as the clot and
any bacteria are removed by
phagocytosis.
185. Maturation
• The granulation tissue is
replaced by fibrous scar
tissue.
• Rearrangement of collagen
fibres occurs and the
strength of the wound
increases.
• In time the scar becomes
less vascular, appearing
after a few months as a fine
line.
• The channels left when
stitches are removed heal
by the same process
187. Secondary healing (healing by second
intention)
• This type of healing follows extensive tissue
destruction or when the edges of a wound cannot be
brought into a position, e.g. varicose ulcers and
pressure (decubitus) ulcers.
• The stages of secondary healing are the same as in
primary healing .
• healing time depends on effective removal of the
cause and the size of the wound
188. Inflammation 2
• This develops on the surface of the healthy tissue
and separation of necrotic tissue (slough) begins, due
mainly to the action of phagocytes in the
inflammatory exudate.
189. Proliferation 2
• This begins as granulation tissue;
consisting of capillary buds,
phagocytes and fibroblasts; develops
at the base of the cavity. Granulation
tissue grows towards the surface,
probably stimulated by macrophages
and a range of locally released
chemicals.
• Phagocytes in the plentiful blood
supply reduce or prevent infection of
the wound by ingesting bacteria after
separation of the slough.
• Some fibroblasts in the wound develop
a limited ability to contract, reducing
the size of the wound and healing
time.
• When granulation tissue reaches the
level of the dermis, epithelial cells at
the edges proliferate and grow
towards the center.
190. Maturation 2
• This occurs by fibrosis ,in which scar tissue replaces
granulation tissue, usually over several months until
the full thickness of the skin is restored.
• Scar tissue is shiny and does not contain sweat
glands, hair follicles or sebaceous glands
191. Fibrosis (scar formation)
• Fibrous tissue is formed during healing by secondary
intention, e.g. following chronic inflammation, persistent
ischaemia, suppuration or extensive trauma. The process
begins with formation of granulation tissue, then, over time,
the inflammatory material is removed leaving only the
collagen fibres secreted by the fibroblasts. Fibrous tissue may
have long-lasting damaging effects.
192. Contd…..
• Adhesions. These consist of fibrous tissue, which causes
adjacent structures to stick together and may limit movement,
e.g. between the layers of pleura, preventing inflation of the
lungs or between loops of bowel, interfering with peristalsis.
193. Contd….
• Fibrosis of infarcts. Blockage of a vessel by a
thrombus or an embolus causes an infarction.
Fibrosis of one large infarct or of numerous small
infarcts may follow, leading to varying degrees of
organ dysfunction, e.g. in heart, brain, kidneys, liver.
194. Tissue shrinkage
• This occurs as fibrous tissue ages. The
• effects depend on the site and extent of the fibrosis, e.g.:
• small tubes, such as blood vessels, air passages, ureters.
197. Complications of wound healing
• Infection.
• enclosure of pus by fibrous tissue that may become
• calcified, harbouring live organisms which may
• become a source of future infection, e.g. tuberculosis
• formation of adhesions between adjacent
• membranes, e.g. pleura, peritoneum
• shrinkage of fibrous tissue as it ages, which may
• reduce the lumen or obstruct a tube, e.g. oesophagus,
• bowel, blood vesse
198. effects of ageing on the skin
• . As the germinative layer becomes
less active, the epidermis thins. The
dermis also thins and there are
fewer elastic and collagen fibres,
which causes wrinkling and sagging.
• These changes may be accelerated
by chronic exposure to strong
sunlight, which is also associated
with the development of malignant
melanoma.
• Sweat gland activity and
temperature regulation become less
efficient, putting older adults at
greater risk in extreme temperatures
making them increasingly prone to
heatstroke and hypothermia.
199. Contd….
• Melanocytes become less active
causing older adults to be more
sensitive to sunlight and more prone
to sunburn.
• In hair, when the pigment melanin is
replaced by air bubbles, greying
occurs. There are fewer active hair
follicles and therefore hair thins
although in some areas this is not the
case; notably the eyebrows, nose and
ears in males, and the face and upper
lip in females.
• Less sebum is secreted making the
skin dry and susceptible to continual
exposure to moisture (maceration).
• Production of vitamin D decreases
predisposing older adults to
deficiency and reduction in bone
strength, especially when exposure to
sunlight is limited
200. Physiology of taste
• Four fundamental sensations of taste have been described –
sweet, sour, bitter and salt; however, others have also been
suggested, including metallic and umami (a Japanese ‘savoury’
taste).
• However, perception varies widely and many ‘tastes’ cannot
be easily classified.
201. Physiology of smell
• The human sense of smell is less acute than in other
animals. Many animals secrete odorous chemicals
called pheromones, which play an important part in
chemical communication in, for example, territorial
behaviour, mating and the bonding of mothers and
their newborn.
202. Contd….
• The role of pheromones in human communication is
unknown.
• All odorous materials give off volatile molecules,
which are carried into the nose with inhaled air and
even very low concentrations, when dissolved in
mucus, stimulate the olfactory chemoreceptors.
203. Contd….
• The air entering the nose is warmed, and convection currents
carry eddies of inspired air to the roof of the nasal cavity.
• ‘Sniffing’ concentrates volatile molecules in there of of the
nose.
• This increases the number of olfactory receptors stimulated
and thus perception of the smell.
204. Contd….
• The sense of smell and the sense of taste are closely
related; the sense of smell may affect the appetite.
• If the odours are pleasant the appetite may improve
and vice versa.
• When accompanied by the sight of food, an
appetising smell increases salivation and stimulates
the digestive system
205. Contd…..
• Inflammation of the nasal mucosa prevents odorous
substances from reaching the olfactory area of the
nose, causing loss of the sense of smell (anosmia).
The usual cause is a cold.
• Adaptation.
• When an individual is continuously exposed to an
odour, perception of the odour decreases and ceases
within a few minutes. This loss of perception affects
only that specific odour.
206. Physiology of balance
• The semicircular canals and the vestibule (utricle and
saccule) are concerned with balance, or equilibrium.
• The arrangement of the three semicircular canals,
one in each plane, not only allows perception of the
position of the head in space but also the direction
and rate of any movement.
207. Contd…
• Any change in the position of the head causes
movement in the perilymph and endolymph, which
bends the hair cells and utricle, saccule and
ampullae.
• The resultant nerve impulses are transmitted by the
vestibular nerve, which joins the cochlear nerve to
form the vestibulo-cochlear nerve.
• The vestibular branch passes first to the vestibular
nucleus, then to the cerebellum.
208. Contd…..
• The cerebellum also receives nerve impulses from
the eyes and proprioceptors (sensory receptors) in
the skeletal muscles and joints.
• The cerebellum coordinates incoming impulses from
the vestibular nerve, the eyes and proprioceptors.
209. Contd…
• Thereafter, impulses are transmitted to the
cerebrum and skeletal muscles enabling perception
of body position and any adjustments needed to
maintain posture and balance.
• This maintains upright posture and fixing of the eyes
on the same point, independently of head
movements.
210.
211. conclusion
• The senses connect humans to the real world,
allowing them to interpret what is happening around
them and respond accordingly. The color of the sky at
dusk, the sound of laughter at a party, the scent of
eucalyptus and pine, the taste of freshly baked
bread—all would be meaningless without the senses.
They not only provide pleasure, but warn of danger.
Traditionally, sight, hearing, smell, taste, and touch
have been considered the five main senses of the
body.
212.
213. Answer the following questions
• Describe the parts of ear
• What is the function of inner ear?
• What is far sightedness and short sightedness?
• Describe the structure of eye?
• What are the functions of skin?
• What is the process of wound healing?
• What is heamostasis?
214. Assignment-7
• Draw the sturcture of ear.
• Draw the structure of eye.
• Draw the structure of skin.
• Explain the physiology of sight.
• Explain the physiology of smell.
• Explain wound healing by secondary intention.
• Discuss about homeostasis and regulation of body
temperature.
215. Referances
Book referances-
• Waugh anne ,grant allison, ‘Anatomy and physiology
in health and illness’;12th edition ublished by
churchill livingstone elsevier pp192-207.
Net references-
https://www.encyclopedia.com/medicine/news-wires-
white-papers-and-books/special-senses viewed on
30/6/2020.
https://www.google.com/search?q=pupil+size+bright+li
ght&tbm viewed on 26/6/2020.