1. The document discusses the host defense mechanisms in the gingiva and periodontium. It describes the roles of saliva, gingival epithelium, gingival crevicular fluid, complement system, and inflammatory cells like neutrophils, macrophages, and lymphocytes in the defense against bacteria. 2. The key inflammatory cells - neutrophils, macrophages, and lymphocytes - work together to detect bacteria via chemotaxis, phagocytose and kill them using various mechanisms, and induce adaptive immune responses through cytokine signaling. 3. The complement system aids in this process through opsonization, chemotaxis, and cytolysis of bacteria. Together these host defenses maintain homeostasis against the bacterial challenge in the