Introduction about Adsorbent,types,selection of Adsorbent and adsorbent used in chromatography

1. ADSORBENT&APPLICATION
ADSORBENT&APPLICATION
ADSORBENTIN
ADSORBENTIN
CHROMATOGRAPHY
CHROMATOGRAPHY
PHARM D PHARMACEUTICAL ANALYSIS UNIT:III
Dr.M.Sumithra M.Pharm,Ph.D
Associate Professor
Department of Pharmaceutical Chemistry and Analysis
School of Pharmaceutical Sciences
VISTAS,Chennai.

2. Introduction
Principle involved in Adsorbent
Types of Adsorbent
Factors Affecting adsorption
Application
Content

3. Introduction - Adsorption
Adsorption is a mass transfer process that is sorption of
gases or solutes by solid or liquid surfaces.
The adsorption on the solid surface is that the molecules or
atoms on the solid surface have residual surface energy due
to unbalanced forces.
Adsorption also defined as adhesion of atoms, ions or
molecules from a gas, liquid or dissolved solid to a surface.
ADSORBATE :
A Substance in which is adsorbed on the surface.

5. Difference Between Adsorption Vs Absorption

6. Material Doing Adsorption ,example:Activated
alumina,Charcoal
Adsorbent

7. The particle should have uniform size. The range 60-200 u.
It should have high mechanical stability.
Not react with solute
Insoluble in solvents or mobile phase
It should be colorless.
It allow free flow of mobile phase.
It useful for wide variety of compounds.
Requirement of Adsorbent

8. Selection of Adsorbent

9. Application
1) Air pollution masks:
These consist of silica gel or activated charcoal powder, when dust or smoke are paused through them, those
particles get adsorbed on the surface of these materials.
2) Separation of noble gases by Dewar’s flask process:
A mixture of noble gases of Ne, Ar, Kr is passed through Dewar’s flask in presence of heated coconut charcoal.
Argon and Krypton gels adsorbed leaving Neon.
3) Purification of water:
By the addition of alum stone to the water, impurities get adsorbed on the alum and water gets purified.
4) Removal of moisture and humidity:
Moisture in the air is removed by placing silica gel on which water molecular gets adsorbed.
5) Adsorption chromatography:
It is used to separate pigments and hormones.
6) Ion exchange method:
In this method of removing the hardness of water, calcium and magnesium ions get adsorbed on the surface of ion
exchange resin

10. References
References
References
i)Gurdeep.R Chatwal.K, and Anand., Instrumental method of Chemical
i)Gurdeep.R Chatwal.K, and Anand., Instrumental method of Chemical
i)Gurdeep.R Chatwal.K, and Anand., Instrumental method of Chemical
Analysis, Himalaya Publishing house, 5 th edition ,New Delhi.2000.
Analysis, Himalaya Publishing house, 5 th edition ,New Delhi.2000.
Analysis, Himalaya Publishing house, 5 th edition ,New Delhi.2000.
ii)Beckett A.H,Stenlake,J.B,Practical Pharmaceutical Chemistry,4
ii)Beckett A.H,Stenlake,J.B,Practical Pharmaceutical Chemistry,4
ii)Beckett A.H,Stenlake,J.B,Practical Pharmaceutical Chemistry,4
th edn.CBS Publishers and Distributors,NewDelhi.2000
th edn.CBS Publishers and Distributors,NewDelhi.2000
th edn.CBS Publishers and Distributors,NewDelhi.2000

11. THANK YOU