Etiopathogenesis and Clinical features

2. ETIOPATHOGENESIS
CLINICAL FEATURES

4. Trauma to Corneal epithelium
Underlying Corneal diseases
Indiscriminate use of Steroids
Immunocompromised subjects
Dry Eyes
Chronic Dacrocystitis or Blepharitis
Lowering of general body resistance

5. 1)Ocular trauma
2)Secondary fungal
ulcers

7. Defect in corneal epithelium
Fungi enter into corneal stroma
Multiplication of fungi
Tissue necrosis & inflammatory reaction
Purulent infiltrate
Saucer shaped ulcer,odematous edges and
surrounding grey zone of infiltration

8. Break through descement membrane,
toxins enter anterior chamber
Irritation of vessels of iris and ciliary body
keratouveitis
Leucocytosis occurs , PMNs poured out by
vessels, gravitate to bottom of anterior
chamber ----- HYPOPYON
 Vascularization develops near ulcer to
restore loss of substance & also supplies
antibodies

9. Line of demarcation forms
Leucocytes macerate & dissolve necrotic tissue
Infiltration & swelling disappear , floor and
edges become smooth and transparent
Healing process continues
Cicatrization and formation of corneal scar

11. • Mycotic keratitis is frequently seen in
field workers, rural areas, tropical
countries and in
immunocompromised individuals.
• In Mycotic keratitis
Symptoms are less prominent
Signs are more marked

12. Decreased vision,
Pain,
Redness,
Lacrimation,
Photophobia,
Foreign body sensation
Visible Whiteness of cornea

20. FUNGAL
KERATITIS
BACTERIAL
KERATITIS
Massive
Thick
Immobile
Unsterile
Small
Fluid
Mobile
Sterile