Virosoft CP4 is a codling moth granulovirus produced by BioTepp, Inc. that provides a natural alternative to chemical insecticides. It works by infecting and killing codling moth larvae when they ingest virus-coated eggs. Clinical studies show Virosoft CP4 significantly reduces codling moth populations with multiple applications at 7-14 day intervals and can be integrated into IPM and organic orchard programs. It has a stable formulation that stores well for many months under different temperatures.

1. VIROSOFT ® CP4 BioTepp, Inc.
January 2011
BioTepp, Inc

2. VIROSOFT CP4
HOW IT WORKS NATURALLY
Virus occlusion bodies (OB) infected larvae
are viral DNA encoded
proteins within a protective The virus infects the larvae,
protein coat. reproduces and destroys
Neonate the apple/pear worm.
After codling moth egg hatch
OBs are eaten by neonate Photos courtesy of
This stops feeding and
larvae. USDA ARS
worms die within 3-7 days.

3. VIROSOFT ® CP4
Unique “Quebec” CP4 virus strain for Codling Moth
larvae population management & control
A naturally effective substitute for CM insecticides
Meets all orchard sustainable & organic standards
No effect on beneficial insects or other creatures
BioTepp, Inc

4. Managing Codling Moth with Granulovirus and Spinosad
Dept. of Entomology, 2003
WSU Tree Fruit Research and Extension Center, Wenatchee, WA
Kieth R. Granger, Jay F. Brunner and Michael D. Doerr
1st
Treatment Rate AI/A Spray generation
(OBx1013) Interval (#aplc.) Moths/tree
Virosoft® 0.38 10 d (8) 0
Untreated --- --- 17.6
Virosoft is a registered trademark of BioTepp, Inc.,
BioTepp, Inc

5. Comparison of Codling Moth Virus Products 2006
Michigan State University
Trevor Nichols Research Complex
L. Gut, M. Hass, C. Hipshier, J. Wise & K. Schoenborn
1st generation
Treatment Rate oz/Ac % shallow % deep
Interval (#aplc.)
stings entries
Virosoft CP4 2 7d (5) 11.2 11.2
Untreated --- --- 8.8 33.5
BioTepp, Inc.

6. VIROSOFT ® CP4
Treated fruit meets sustainable standards
OMRI Listed®
BioTepp, Inc

7. VIROSOFT FORMULA IS STABLE
J ECON ENTOMOL. 2008 APR;101(2):288-94.
EFFECT OF TEMPERATURE ON LONG-TERM STORAGE OF CMGV FORMULATIONS.
LACEY LA, HEADRICK HL, ARTHURS SP.
Storage Stability
36° F 77° F 95° F
Test Temperature
VIROSOFT CP4 31 mo.+ 31 mo.+ 9 mo.
Months with = to or > 95% CM larvae mortality at above temperatures
+ stability test stopped before end point reached
Will store even longer if refrigerated or frozen
BioTepp, Inc

8. VIROSOFT ® CP4
Apply 2-3.2 oz/acre every 7-14 days
If Codling Moth pressure is high use 7 day interval
Begin sprays at egg hatch (2 weeks after petal fall) and continue as
needed but apply at least 2 sprays per CM generation
Apply in enough water for thorough coverage of the tree bark, foliage
and fruit
May be applied to Apple, Pear, Plum & Walnut trees
BioTepp, Inc

9. VIROSOFT ® CP4 IN PROGRAMS
Optimize control of Codling Moth and
other insects:
Apply Virosoft CP4 in IPM programs with
dormant oil, mating disruption, other
larvacides, kaolin clay and cultural controls
BioTepp, Inc

10. IP M & ORG A N IC P ROG RAM E X AMP LE S
AGAINST 1 ST G E N E RA TI ON C M & L R
S OF T S TA RT AL L OWS BENEFICIAL S TO AS S IS T
A S S UMES US E OF M A TI N G D I S RUP TION & S C OUTI N G
Timing Delayed
Petal Fall 100-200 1st Cover 1st Cover 2nd Cover
Delayed 50-100 Degree 220-250 350 450-600
Dormant Degree Days Degree Degree Degree
Days Days Days Days
Target LR larvae & CM eggs CM larvae CM larvae CM larvae
CM eggs CM eggs
IPM 1 larvacide Virosoft® + Virosoft +
OP+0il + oil larvacide lavacide
IPM 2 ovacide/ Virosoft + Virosoft +
OP+0il larvacide larvacide larvacide
Organic Virosoft Virosoft
Hort 0il Entrust + oil + kaolin
+ oil +kaolin or Entrust®
Virosoft is a registered trademark of BioTepp, Inc. Entrust is registered trademark of Dow Agrosciences LLC
BioTepp, Inc

11. VIROSOFT CP4
Recommended reading:
Lacey, Lawrence A., Thomson, Donald, Vincent,
Charles and Arthurs, Steven P.(2008)'Codling moth
granulovirus: a comprehensive review',Biocontrol
Science and Technology,18:7,639 — 663
BioTepp, Inc

12. THANK YOU
TEL. 916 719 6176
KSDAVISCA@GMAIL.COM
WWW.BIOTEPP.COM
BioTepp, Inc