UAIPD 10-0028
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The document describes a technology for using shape-controlled magnetic nanoparticles as T1 contrast agents for magnetic resonance imaging (MRI) to address current problems with existing contrast agents. By tuning the shape of iron oxide nanoparticles into whiskers, plates or wires, it increases their effectiveness as contrast agents by providing brighter, clearer images and enabling targeted imaging with an enhanced residence time. The technology was developed by Dr. Yuping Bao at the University of Alabama and has the potential advantages of being safer, more effective and increasing contrast agent retention time compared to existing agents.
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3) This decreases delamination of the coating by reducing the amount of stress, extending drill life and increasing the number of holes drilled before failure.
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The nitrogen-vacancy (NV) center in diamond is a promising candidate for applications in quantum technologies due to its favorable properties. As a microscopic single-photon source, the NV center has stable fluorescence even at room temperature, a long spin coherence time, and broadband emission spectrum. Potential applications of the NV center include quantum computing, cryptography, and information processing by generating entanglement and teleporting quantum information. The NV center could also be used for high-resolution fluorescent imaging and magnetic sensing/imaging at the nanoscale due to its photostability and ability to initialize and readout spin states optically.
Mri final ppt
Magnetic resonance imaging (MRI) uses strong magnets and radio waves to produce detailed images of the inside of the body without using ionizing radiation. An MRI machine contains a powerful magnet to align hydrogen atoms in the body. Radio waves are then used to excite the atoms, which emit signals as they relax. These signals are detected by antennas and used by a computer to generate 2D or 3D images of tissues and organs. MRI provides excellent soft tissue contrast and is useful for imaging the brain, muscles, joints, and other internal organs. While it has advantages over CT in avoiding radiation, MRI scans can be costly and some patients may find the enclosed scanner space claustrophobic.
PROTON BEAM THERAPY.pptx
Proton beam therapy is an advanced form of radiation therapy that uses proton particles instead of X-rays to treat cancerous tumors. It was first proposed in 1946 and developed further in the late 1970s with improved imaging and computer technology. Protons deposit most of their energy at the tumor site, allowing for higher doses to be applied while minimizing damage to surrounding healthy tissues compared to traditional photon radiation therapy. Proton beam therapy involves accelerating protons to high speeds using devices like cyclotrons or synchrotrons, precisely aiming the proton beam at the tumor, and delivering the proton radiation in a narrow area using techniques like pencil beam scanning or double scattering. Rigorous quality assurance procedures ensure the safe and accurate delivery of the proton treatment
MRI
Magnetic resonance imaging (MRI) uses strong magnets and radio waves to generate detailed images of the inside of the body. MRI machines contain superconducting magnets that create a strong magnetic field, gradient coils that alter the field to create slices for imaging, and an RF coil that emits radio waves. During an MRI scan, hydrogen atoms in the body are aligned by the magnetic field and excited with radio waves, emitting signals used to construct 2D and 3D images of tissues and organs. MRI provides excellent soft tissue contrast and is commonly used to image the brain, heart, joints, and other areas to evaluate injuries, diseases, and functional abnormalities.
sensors & actuators.
This document provides an overview of sensors and actuators. It defines sensors as devices that can detect and sense signals from various sources, like optical, biomedical, electrical, physical or mechanical signals. Nanosensors are defined as tiny sensors only a few nanometers in size. The document outlines different types of sensors like optical, bio, chemical and physical sensors and provides examples. It also discusses applications of sensors like Pebble sensors, twin-action nanosensors and multimodal nanosensors. Actuators are defined as devices that convert a control signal into motion. The document outlines actuator design goals and types like hydraulic, pneumatic, piezoelectric, electromagnetic and mechanical actuators. It provides examples of applications for
MRI
Magnetic resonance imaging (MRI) uses strong magnetic fields and radio waves to produce detailed images of the inside of the body without using ionizing radiation. Dr. Damadian first proposed using MRI to externally scan the human body for signs of malignancy in 1969. An MRI machine contains a magnet to align hydrogen atoms, gradient coils to spatially encode signals, and radio frequency coils to transmit and receive signals used to form images. A computer system controls the imaging process and reconstructs images from the MRI signals. Contrast agents containing gadolinium may be used to improve visibility of structures.
Nano - Robotics - The future world
Nanorobotics involves the design and use of robots at the nanoscale level. Key points include:
- Nanorobots are designed to perform tasks at the nanometer scale and are made of components like carbon nanotubes.
- They have a variety of potential medical applications like cancer treatment, breaking up kidney stones, and restoring artery health.
- Challenges include powering nanobots, controlling them, and ensuring they function safely inside the human body.
- Future developments could include using nanobots to repair equipment in space or detect hazardous microbes in the environment.
Nanotechnology in Engineering
Nanotechnology involves manipulating matter at the nanoscale, between 1 to 100 nanometers. It can be used to create new materials and devices with unique properties. Some common nanomaterials include carbon nanotubes, nanoparticles, nanowires, and quantum dots. Nanotechnology has applications in engineering like improving the strength of materials, electronics by enabling smaller devices, medicine for targeted drug delivery, and more. However, there are also concerns about the health and environmental impacts of nanoparticles that need further research. The future prospects of nanotechnology include overcoming challenges like cost to enable widespread applications across many industries.
Medical imaging
This document provides an overview of various medical imaging and treatment techniques, including endoscopes and diagnostic X-ray machines. It discusses endoscopes, noting they can have rigid or flexible tubes, lenses to transmit images, and channels to allow entry of instruments. Diagnostic X-ray machines are described as using a cathode ray tube to produce X-rays via bremsstrahlung and characteristic radiation when electrons hit a tungsten target. The energy of the resulting X-ray photons is discussed. Safety aspects of X-ray machines are also mentioned.
NDE by magnetic resonance.docx
This document provides an overview of magnetic resonance techniques for non-destructive testing, specifically nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI). It discusses the basic principles of how NMR and MRI work, including using magnetic fields and radio waves to detect atomic nuclei like hydrogen protons. Applications mentioned include material characterization, medical imaging, and purity analysis. The instrumentation for both techniques is also described.
Similar to UAIPD 10-0028 (20)
International Journal of Image Processing (IJIP) Volume (1) Issue (1)
International Journal of Image Processing (IJIP) Volume (1) Issue (1)
ECE 695 group Quantum photonics_ nitrogen-vacancy centers in diamond
ECE 695 group Quantum photonics_ nitrogen-vacancy centers in diamond
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UAIPD 16-0022
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This document describes a new multi-piezoelectric microcantilever technology that improves scanning probe microscopy. It uses multiple piezoelectric materials attached to a microcantilever to sense its deflection without a laser, and a consensus algorithm to provide the most accurate estimation. This novel combination increases scanning probe microscope accuracy and enables operation even if some piezoelectric sensors fail. The technology was invented by Dr. Nima Mahmoodi from the University of Alabama Mechanical Engineering department.
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This document describes an educational research kit that uses CRISPR-Cas10 gene editing technology. The kit allows students to explore gene transfer between phages, which is currently not well understood. It leverages the accessibility of CRISPR to enable high school, college, and graduate students to learn about gene editing and DNA analysis of bacteria. The technology was successfully piloted and demonstrates that CRISPR research can be made accessible through an educational kit. The kit was invented by Dr. Asma Hatoum, an assistant professor of biological sciences.
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UAIPD 15-0011
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Authoring a personal GPT for your research and practice: How we created the Q...
Thematic analysis in qualitative research is a time-consuming and systematic task, typically done using teams. Team members must ground their activities on common understandings of the major concepts underlying the thematic analysis, and define criteria for its development. However, conceptual misunderstandings, equivocations, and lack of adherence to criteria are challenges to the quality and speed of this process. Given the distributed and uncertain nature of this process, we wondered if the tasks in thematic analysis could be supported by readily available artificial intelligence chatbots. Our early efforts point to potential benefits: not just saving time in the coding process but better adherence to criteria and grounding, by increasing triangulation between humans and artificial intelligence. This tutorial will provide a description and demonstration of the process we followed, as two academic researchers, to develop a custom ChatGPT to assist with qualitative coding in the thematic data analysis process of immersive learning accounts in a survey of the academic literature: QUAL-E Immersive Learning Thematic Analysis Helper. In the hands-on time, participants will try out QUAL-E and develop their ideas for their own qualitative coding ChatGPT. Participants that have the paid ChatGPT Plus subscription can create a draft of their assistants. The organizers will provide course materials and slide deck that participants will be able to utilize to continue development of their custom GPT. The paid subscription to ChatGPT Plus is not required to participate in this workshop, just for trying out personal GPTs during it.
Candidate young stellar objects in the S-cluster: Kinematic analysis of a sub...
Context. The observation of several L-band emission sources in the S cluster has led to a rich discussion of their nature. However, a definitive answer to the classification of the dusty objects requires an explanation for the detection of compact Doppler-shifted Brγ emission. The ionized hydrogen in combination with the observation of mid-infrared L-band continuum emission suggests that most of these sources are embedded in a dusty envelope. These embedded sources are part of the S-cluster, and their relationship to the S-stars is still under debate. To date, the question of the origin of these two populations has been vague, although all explanations favor migration processes for the individual cluster members. Aims. This work revisits the S-cluster and its dusty members orbiting the supermassive black hole SgrA* on bound Keplerian orbits from a kinematic perspective. The aim is to explore the Keplerian parameters for patterns that might imply a nonrandom distribution of the sample. Additionally, various analytical aspects are considered to address the nature of the dusty sources. Methods. Based on the photometric analysis, we estimated the individual H−K and K−L colors for the source sample and compared the results to known cluster members. The classification revealed a noticeable contrast between the S-stars and the dusty sources. To fit the flux-density distribution, we utilized the radiative transfer code HYPERION and implemented a young stellar object Class I model. We obtained the position angle from the Keplerian fit results; additionally, we analyzed the distribution of the inclinations and the longitudes of the ascending node. Results. The colors of the dusty sources suggest a stellar nature consistent with the spectral energy distribution in the near and midinfrared domains. Furthermore, the evaporation timescales of dusty and gaseous clumps in the vicinity of SgrA* are much shorter ( 2yr) than the epochs covered by the observations (≈15yr). In addition to the strong evidence for the stellar classification of the D-sources, we also find a clear disk-like pattern following the arrangements of S-stars proposed in the literature. Furthermore, we find a global intrinsic inclination for all dusty sources of 60 ± 20◦, implying a common formation process. Conclusions. The pattern of the dusty sources manifested in the distribution of the position angles, inclinations, and longitudes of the ascending node strongly suggests two different scenarios: the main-sequence stars and the dusty stellar S-cluster sources share a common formation history or migrated with a similar formation channel in the vicinity of SgrA*. Alternatively, the gravitational influence of SgrA* in combination with a massive perturber, such as a putative intermediate mass black hole in the IRS 13 cluster, forces the dusty objects and S-stars to follow a particular orbital arrangement. Key words. stars: black holes– stars: formation– Galaxy: center– galaxies: star formation
MICROBIAL INTERACTION PPT/ MICROBIAL INTERACTION AND THEIR TYPES // PLANT MIC...
MICROBIAL INTERACTION PPT/ MICROBIAL INTERACTION AND THEIR TYPES // PLANT MIC...ABHISHEK SONI NIMT INSTITUTE OF MEDICAL AND PARAMEDCIAL SCIENCES , GOVT PG COLLEGE NOIDA
Microbial interaction
Microorganisms interacts with each other and can be physically associated with another organisms in a variety of ways.
One organism can be located on the surface of another organism as an ectobiont or located within another organism as endobiont.
Microbial interaction may be positive such as mutualism, proto-cooperation, commensalism or may be negative such as parasitism, predation or competition
Types of microbial interaction
Positive interaction: mutualism, proto-cooperation, commensalism
Negative interaction: Ammensalism (antagonism), parasitism, predation, competition
I. Mutualism:
It is defined as the relationship in which each organism in interaction gets benefits from association. It is an obligatory relationship in which mutualist and host are metabolically dependent on each other.
Mutualistic relationship is very specific where one member of association cannot be replaced by another species.
Mutualism require close physical contact between interacting organisms.
Relationship of mutualism allows organisms to exist in habitat that could not occupied by either species alone.
Mutualistic relationship between organisms allows them to act as a single organism.
Examples of mutualism:
i. Lichens:
Lichens are excellent example of mutualism.
They are the association of specific fungi and certain genus of algae. In lichen, fungal partner is called mycobiont and algal partner is called
II. Syntrophism:
It is an association in which the growth of one organism either depends on or improved by the substrate provided by another organism.
In syntrophism both organism in association gets benefits.
Compound A
Utilized by population 1
Compound B
Utilized by population 2
Compound C
utilized by both Population 1+2
Products
In this theoretical example of syntrophism, population 1 is able to utilize and metabolize compound A, forming compound B but cannot metabolize beyond compound B without co-operation of population 2. Population 2is unable to utilize compound A but it can metabolize compound B forming compound C. Then both population 1 and 2 are able to carry out metabolic reaction which leads to formation of end product that neither population could produce alone.
Examples of syntrophism:
i. Methanogenic ecosystem in sludge digester
Methane produced by methanogenic bacteria depends upon interspecies hydrogen transfer by other fermentative bacteria.
Anaerobic fermentative bacteria generate CO2 and H2 utilizing carbohydrates which is then utilized by methanogenic bacteria (Methanobacter) to produce methane.
ii. Lactobacillus arobinosus and Enterococcus faecalis:
In the minimal media, Lactobacillus arobinosus and Enterococcus faecalis are able to grow together but not alone.
The synergistic relationship between E. faecalis and L. arobinosus occurs in which E. faecalis require folic acid
Direct Seeded Rice - Climate Smart Agriculture
Direct Seeded Rice - Climate Smart AgricultureInternational Food Policy Research Institute- South Asia Office
PPT on Direct Seeded Rice presented at the three-day 'Training and Validation Workshop on Modules of Climate Smart Agriculture (CSA) Technologies in South Asia' workshop on April 22, 2024.
JAMES WEBB STUDY THE MASSIVE BLACK HOLE SEEDS
The pathway(s) to seeding the massive black holes (MBHs) that exist at the heart of galaxies in the present and distant Universe remains an unsolved problem. Here we categorise, describe and quantitatively discuss the formation pathways of both light and heavy seeds. We emphasise that the most recent computational models suggest that rather than a bimodal-like mass spectrum between light and heavy seeds with light at one end and heavy at the other that instead a continuum exists. Light seeds being more ubiquitous and the heavier seeds becoming less and less abundant due the rarer environmental conditions required for their formation. We therefore examine the different mechanisms that give rise to different seed mass spectrums. We show how and why the mechanisms that produce the heaviest seeds are also among the rarest events in the Universe and are hence extremely unlikely to be the seeds for the vast majority of the MBH population. We quantify, within the limits of the current large uncertainties in the seeding processes, the expected number densities of the seed mass spectrum. We argue that light seeds must be at least 103 to 105 times more numerous than heavy seeds to explain the MBH population as a whole. Based on our current understanding of the seed population this makes heavy seeds (Mseed > 103 M⊙) a significantly more likely pathway given that heavy seeds have an abundance pattern than is close to and likely in excess of 10−4 compared to light seeds. Finally, we examine the current state-of-the-art in numerical calculations and recent observations and plot a path forward for near-future advances in both domains.
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...Advanced-Concepts-Team
Presentation in the Science Coffee of the Advanced Concepts Team of the European Space Agency on the 07.06.2024.
Speaker: Diego Blas (IFAE/ICREA)
Title: Gravitational wave detection with orbital motion of Moon and artificial
Abstract:
In this talk I will describe some recent ideas to find gravitational waves from supermassive black holes or of primordial origin by studying their secular effect on the orbital motion of the Moon or satellites that are laser ranged.Discovery of An Apparent Red, High-Velocity Type Ia Supernova at 𝐳 = 2.9 wi...
We present the JWST discovery of SN 2023adsy, a transient object located in a host galaxy JADES-GS
+
53.13485
−
27.82088
with a host spectroscopic redshift of
2.903
±
0.007
. The transient was identified in deep James Webb Space Telescope (JWST)/NIRCam imaging from the JWST Advanced Deep Extragalactic Survey (JADES) program. Photometric and spectroscopic followup with NIRCam and NIRSpec, respectively, confirm the redshift and yield UV-NIR light-curve, NIR color, and spectroscopic information all consistent with a Type Ia classification. Despite its classification as a likely SN Ia, SN 2023adsy is both fairly red (
�
(
�
−
�
)
∼
0.9
) despite a host galaxy with low-extinction and has a high Ca II velocity (
19
,
000
±
2
,
000
km/s) compared to the general population of SNe Ia. While these characteristics are consistent with some Ca-rich SNe Ia, particularly SN 2016hnk, SN 2023adsy is intrinsically brighter than the low-
�
Ca-rich population. Although such an object is too red for any low-
�
cosmological sample, we apply a fiducial standardization approach to SN 2023adsy and find that the SN 2023adsy luminosity distance measurement is in excellent agreement (
≲
1
�
) with
Λ
CDM. Therefore unlike low-
�
Ca-rich SNe Ia, SN 2023adsy is standardizable and gives no indication that SN Ia standardized luminosities change significantly with redshift. A larger sample of distant SNe Ia is required to determine if SN Ia population characteristics at high-
�
truly diverge from their low-
�
counterparts, and to confirm that standardized luminosities nevertheless remain constant with redshift.
fermented food science of sauerkraut.pptx
This ppt contains the production of a fermented food name - sauerkraut
Alternate Wetting and Drying - Climate Smart Agriculture
Alternate Wetting and Drying - Climate Smart AgricultureInternational Food Policy Research Institute- South Asia Office
PPT on Alternate Wetting and Drying presented at the three-day 'Training and Validation Workshop on Modules of Climate Smart Agriculture (CSA) Technologies in South Asia' workshop on April 22, 2024. (June 12, 2024) Webinar: Development of PET theranostics targeting the molecu...
(June 12, 2024) Webinar: Development of PET theranostics targeting the molecu...Scintica Instrumentation
Targeting Hsp90 and its pathogen Orthologs with Tethered Inhibitors as a Diagnostic and Therapeutic Strategy for cancer and infectious diseases with Dr. Timothy Haystead.Randomised Optimisation Algorithms in DAPHNE
Slides from talk:
Aleš Zamuda: Randomised Optimisation Algorithms in DAPHNE .
Austrian-Slovenian HPC Meeting 2024 – ASHPC24, Seeblickhotel Grundlsee in Austria, 10–13 June 2024
https://ashpc.eu/
The debris of the ‘last major merger’ is dynamically young
The Milky Way’s (MW) inner stellar halo contains an [Fe/H]-rich component with highly eccentric orbits, often referred to as the
‘last major merger.’ Hypotheses for the origin of this component include Gaia-Sausage/Enceladus (GSE), where the progenitor
collided with the MW proto-disc 8–11 Gyr ago, and the Virgo Radial Merger (VRM), where the progenitor collided with the
MW disc within the last 3 Gyr. These two scenarios make different predictions about observable structure in local phase space,
because the morphology of debris depends on how long it has had to phase mix. The recently identified phase-space folds in Gaia
DR3 have positive caustic velocities, making them fundamentally different than the phase-mixed chevrons found in simulations
at late times. Roughly 20 per cent of the stars in the prograde local stellar halo are associated with the observed caustics. Based
on a simple phase-mixing model, the observed number of caustics are consistent with a merger that occurred 1–2 Gyr ago.
We also compare the observed phase-space distribution to FIRE-2 Latte simulations of GSE-like mergers, using a quantitative
measurement of phase mixing (2D causticality). The observed local phase-space distribution best matches the simulated data
1–2 Gyr after collision, and certainly not later than 3 Gyr. This is further evidence that the progenitor of the ‘last major merger’
did not collide with the MW proto-disc at early times, as is thought for the GSE, but instead collided with the MW disc within
the last few Gyr, consistent with the body of work surrounding the VRM.
快速办理(UAM毕业证书)马德里自治大学毕业证学位证一模一样
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3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
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Applied Science: Thermodynamics, Laws & Methodology.pdf
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
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UAIPD 10-0028
- 1. UAIPD 10-0028 Dr. Yuping Bao Shape-controlled Magnetic Nanoparticles as T1 Contrast Agents for Magnetic Resonance Imaging
- 2. Current Problems • Magnetic Resonance Imaging (MRI) – Powerful, non-invasive diagnostic tool for living organisms – Provides real-time images with great spatial resolution • Problems – Potential toxicity of current T1 contrast agent – Lack of targeting imaging ability – Relative short residence time – Relies on omnipresent mechanisms
- 3. • Variety of nanoparticle (NP) shapes – Tune the relaxivity of magnetic NP’s as T1 contrast agents for MRI • Modification of the contrast agent structure into whiskers, plate or wire shapes – Increases the effectiveness of the contrast agent • Method for targeting image – Target imaging can be realized and further enhancement of the residence time Technology Figure 1. Shape-controlled iron oxide nanoparticles: (a) nanowhiskers, (b) uniform thin nanowires along with irregular shaped particles, (c) porous nanorices, and (d) nanoplates
- 4. • Removes toxicity of widely used T1 contrast agent • Produce brighter and clearer quality • Provide targeting imaging ability • Enhance contrast agent residence time • Easy to produce • Safer and more effective • Increase retention – Through nanowires Advantages
- 5. • Dr. Yuping Bao – Associate Professor – 2 patent applications • Departments – Center for Materials for Information Technologies – Chemical and Biological Engineering Inventor ybao@eng.ua.edu
- 6. Office for Technology Transfer 720 2nd Ct E Tuscaloosa, AL 35401 UAIPD 10-0028 OTT@UA.edu www.OTT.UA.edu
Editor's Notes
- Should read like Wikipedia entry. Try to focus on the high points.
- Closing slide. Make sure to add in UAIPD# then change font back to black.