This document outlines transmission-based precaution techniques, including airborne, droplet, and contact precautions. Airborne precautions are for diseases transmitted through small particles that remain suspended in the air, like measles or tuberculosis, and involve respiratory protection, negative pressure rooms, and appropriate ventilation. Droplet precautions are for diseases transmitted through large respiratory droplets, like influenza, and involve masks within 3 feet and private rooms. Contact precautions are for diseases transmitted through direct or indirect contact and involve private rooms, dedicated or disposable equipment, gloves, and hand hygiene.
Risk assessment must be considered whenever patient required for isolation
Type of isolation are source or protective
Tires of precautions include stander precaution and transmission based precaution which based on 3 mode of transmission contact, airborne, or droplets.
Risk assessment must be considered whenever patient required for isolation
Type of isolation are source or protective
Tires of precautions include stander precaution and transmission based precaution which based on 3 mode of transmission contact, airborne, or droplets.
A short brief on 'Hospital Acquired Infections' (HAI) or 'Nosocomial Infection' (NI) for M Phil, MPH and Advance Course in Hospital Management/ Administration
The nursing technique by which a patient with an infectious disease is prevented from infecting other people is called barrier nursing.Hand hygiene is the simplest, most effective measure for infection control.Contact Precautions
Airborne Precautions
Droplet Precautions
Three more elements have been added to standard precautions. They are:
4.1 Respiratory hygiene/cough etiquette
4.2 Safe injection practices
4.3Use of masks for insertion of catheters or injection into spinal or epidural areas
Needle stick injury and hazards of needle stickNCRIMS, Meerut
Needlestick injuries are wounds caused by sharps that accidentally puncture the skin.
Needlestick injuries are a hazard for people who work with hypodermic syringes and other needle equipment.
These injuries can occur at any time when people use, disassemble, or dispose of needles.
Hospital acquired infections: The different common sources of infection, their routes of spread and the growing antimicrobial resistance. Also includes a discussion on hospital Infection prevention and control guidelines and the universal and standard precautions.
A short brief on 'Hospital Acquired Infections' (HAI) or 'Nosocomial Infection' (NI) for M Phil, MPH and Advance Course in Hospital Management/ Administration
The nursing technique by which a patient with an infectious disease is prevented from infecting other people is called barrier nursing.Hand hygiene is the simplest, most effective measure for infection control.Contact Precautions
Airborne Precautions
Droplet Precautions
Three more elements have been added to standard precautions. They are:
4.1 Respiratory hygiene/cough etiquette
4.2 Safe injection practices
4.3Use of masks for insertion of catheters or injection into spinal or epidural areas
Needle stick injury and hazards of needle stickNCRIMS, Meerut
Needlestick injuries are wounds caused by sharps that accidentally puncture the skin.
Needlestick injuries are a hazard for people who work with hypodermic syringes and other needle equipment.
These injuries can occur at any time when people use, disassemble, or dispose of needles.
Hospital acquired infections: The different common sources of infection, their routes of spread and the growing antimicrobial resistance. Also includes a discussion on hospital Infection prevention and control guidelines and the universal and standard precautions.
Hospital Aquired Infections with special consideration to surgical site infections...also case presentation in the begining followed by literature review
Ethopia: Pros and Cons of Health the Health System (2015)Amanda Rostic, MPH
This presentation was for my health administration course. I selected Ethiopia and I discussed the structure of their health system. I looked at several different health indicators and listed several overall pros and cons.
A. Standard Precautions-Standard precautions are to be followed for all patients, irrespective of their infection status.
These are to be used to avoid contact with blood, body fluids, secretions and excretions regardless of whether contaminated grossly with blood or not; non intact skin; and mucous membrane.
They are the basic level of infection control precautions which are to be used, as a minimum, in the care of all patients
Infection control measure to be undertaken by hospital- Use standard precaution for the care of all patients.
This general mandate is necessary because it is sometimes not known if the patient is colonized or infected with certain pathogenic microorganisms.
Barrier precautions reduce the need to handle sharps.
B. Transmission Precautions- The second tier condenses the disease-specific and categories approach to isolation into new transmission categories to be taken based on the route of transmission of organisms like contact precautions, airborne precautions, etc.
These precautions are designed for specific patients with highly transmissible pathogens
any infection developing in a patient after
two days of hospitalization can be labelled as healthcare-associated infection (HAI)or hospital Aquired infection . Among them, there are four
major types which are commonly encountered and
therefore need to be discussed in detail. These are also the
HAIs for which surveillance is recommended.
1. Catheter-associated urinary tract infection (CAUTI)
2. Catheter-related bloodstream infection (CRBSI)
3. Ventilator-associated pneumonia (VAP)
4. Surgical site infection (SSI).
Out of these, the first three (CAUTI, CRBSI, VAP) are
together called as device associated infections (DAIs).
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
3. • Designed to reduce the risk of
airborne transmission of infectious
agents through dissemination of
small droplet nuclei >5 microns in
size or small-particle residue of
evaporated droplets that may
remain suspended in the air for long
periods or dust particles containing
the infectious agent.
4. • Microorganisms carried in this
manner can be dispersed widely by
air currents and may become
inhaled by or deposited on a
susceptible host within the same
room or over a longer distance from
the source patient
• Therefore, special air handling,
filtration, and ventilation are required
5. • Examples:
• measles, varicella (including
disseminated zoster), TB
• Wear respiratory protection when
entering the room of a patient with
known or suspected PTB or any of
the other known or suspected
airborne-transmitted diseases
• at least an N-95 respirator or PAPR
6. • Place the patient in a private room
that has:
• Monitored negative air pressure in
relation to the surrounding areas.
• At least 6 but preferably 12 air
changes per hour.
• Appropriate discharge of air
outdoors or monitored high-
efficiency filtration of room air before
recirculation.
• Door that is closed at all times with
the patient in the room.
7. • Health care workers who are
susceptible should not enter the
rooms of patients known or
suspected to have:
• measles (rubeola) or chickenpox
(varicella)
• If susceptible individuals must enter
the room, they should wear a N-95
or PAPR mask
• Persons immune to rubeola or
varicella need not wear a mask
8. • Limit the transport of the patient
from the room to essential purposes
only.
• Minimize patient dispersal of droplet
nuclei by placing a surgical mask on the
patient.
• Notify the destination department about
the patient and the patient's status so
they can provide protection to their staff
and other patients.
• Minimize the time the patient is in the
visiting department.
10. • Designed for care of patients known
or suspected to be infected with
microorganisms transmitted by
droplets (large particles) that can be
generated by the patient when
coughing, sneezing, talking, or
during the performance of
procedures.
• Wear a mask when working within 3
feet (0.9 m) of the patient's mouth.
11. • Examples:
• Invasive Haemophilus influenzae type b
disease, including meningitis,
pneumonia, epiglottitis, sepsis
• Invasive N. meningitidis disease,
including meningitis, pneumonia, sepsis
• Diphtheria, mycoplasma pneumonia,
pertussis, pneumonic plague,
streptococcal pharyngitis, pneumonia,
or scarlet fever in infants and young
children
• Adenovirus, influenza, mumps,
parvovirus B19, rubella
12. • Place the patient in a private room.
• When a private room is not
available, place patients with the
same microorganism together
(cohorting).
• If neither of these is possible,
maintain spatial separation of at
least 3 feet between the infected
patient and other patients
13. • Special air handling and ventilation
are not necessary, the door may
remain open
• Limit the transport of the patient
from the room to essential purposes
only.
• If transport is necessary, minimize
dispersal of droplets by masking the
patient.
15. • Used for patients known or
suspected to be infected or
colonized with epidemiologically
important microorganisms that can
be transmitted by direct or indirect
contact
16. • direct contact with the patient
• skin-to-skin or patient's skin to staff's
clothing as contact occurs when
performing patient care activities
that require touching the patient's
skin
• indirect contact
• touching with environmental
surfaces or patient care items in the
patient's environment.
17. • Examples :
• Methicillin (oxacillin)-resistant
Staphylococcus aureus (MRSA
[ORSA])
• Vancomycin-resistant Enterococcus.
• Vancomycin-intermediate-resistant S.
aureus, also known as glycopeptide-
resistant S. aureus.
• Clostridium difficile (when patient has
diarrhea).
• For diapered or incontinent patients,
Escherichia coli 0157:H7, shigella,
hepatitis A, rotavirus.
18. • Respiratory syncytial virus,
parainfluenza virus, or enteroviral
infections in young children; diphtheria;
herpes simplex virus (primary cases).
• Impetigo, major (noncontained)
abscesses, cellulitis, or decubiti.
• Pediculosis, scabies, staphylococcal
furunculosis in infants and young
children.
• Herpes zoster.
19. • Place the patient in a private room
or in a room with a patient who has
the same microorganism (cohorting)
• When possible, dedicate the use of
noncritical patient care equipment to
a single patient
• Consider disposable equipment
where possible.
• Thoroughly clean and disinfect
reusable equipment before use for
another patient.
20. • In addition to wearing gloves as
outlined under Standard
Precautions, everyone (including
visitors) must wear gloves when
entering the room.
• Change gloves after contact with
infective material, such as feces and
wound drainage.
21. • Remove gloves before leaving the
patient's environment and perform
appropriate hand hygiene
immediately with an antimicrobial
soap or alcohol-based waterless
antiseptic agent.
• After glove removal and hand
hygiene, make sure that hands do
not touch potentially contaminated
environmental surfaces or items in
the patient's room.