Toxic shock syndrome is a rare, life-threatening complication caused by certain bacterial infections, often from toxins produced by Staphylococcus aureus or group A streptococcus bacteria. It has historically been associated with superabsorbent tampon use but can affect anyone, especially if they have wounds, surgery, or viral infections. Symptoms progress rapidly and can include shock, renal failure, and even death. Diagnosis involves testing blood and samples from swabs of bodily areas for the infections. Treatment requires hospitalization, antibiotics, fluids, and possibly surgery or dialysis. Prevention involves using the lowest absorbency tampons or pads and changing them frequently.