This document summarizes a 6-year case study of whitefly management in a 10-hectare greenhouse in Northern Greece. The study utilized an integrated pest management approach considering principles of environmental sustainability, food safety, and market demands. Key factors for effective whitefly management included high hygiene status, adequate scouting levels, targeted chemical applications, proper introduction of predatory mites like Macrolophus caliginosus and Euseius eremicus, and quickly addressing any issues like broken insect nets. With the total greenhouse management approach, the grower was able to balance economic results, consumer safety, and business sustainability.