This document discusses future innovations in biotechnology that could improve crop yields and discusses regulatory hurdles that slow their development. It outlines technologies like modifying cell walls for biofuels, introducing traits like nitrogen fixation, and developing biosensors in plants. However, the current regulatory system in the US takes 10+ years and $20M to approve each technology. This excludes public researchers and limits realizing benefits. The document calls for new strategies to sustainably increase production through approaches like adapting crops to harsh environments, engineering nutrition, and exploiting natural sensing mechanisms.