The document summarizes the anatomy and physiology of the special senses, focusing on vision and hearing. It describes:
1) The accessory structures of the eye that facilitate vision like the eyelids, conjunctiva, and lacrimal glands.
2) The three layers that make up the walls of the eyeball - fibrous tunic, vascular tunic, and sensory tunic containing photoreceptors.
3) How sound waves are collected by the outer ear, amplified by the middle ear bones, and transduced into nerve impulses in the inner ear for hearing.
This ppt file belongs to Mr. Yonas Akalu one of my best instructors ...
Vision is by far the most used of the five senses and is one of the primary means that we use to gather information from our surroundings. More than 75% of the information we receive about the world around us consists of visual information.
The eye is often compared to a camera. Each gathers light and then transforms that light into a "picture." Both also have lenses to focus the incoming light. Just as a camera focuses light onto the film to create a picture, the eye focuses light onto a specialized layer of cells, called the retina.
The human eye is an organ which reacts to light and pressure. As a sense organ, the mammalian eye allows vision. Human eyes help to provide a three dimensional, moving image, normally coloured in daylight. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth. The human eye can differentiate between about 10 million colors[1] and is possibly capable of detecting a single photon.
he sense organs — eyes, ears, tongue, skin, and nose — help to protect the body. The human sense organs contain receptors that relay information through sensory neurons to the appropriate places within the nervous system.
Each sense organ contains different receptors.
General receptors are found throughout the body because they are present in skin, visceral organs (visceral meaning in the abdominal cavity), muscles, and joints.
Special receptors include chemoreceptors (chemical receptors) found in the mouth and nose, photoreceptors (light receptors) found in the eyes, and mechanoreceptors found in the ears.
This ppt file belongs to Mr. Yonas Akalu one of my best instructors ...
Vision is by far the most used of the five senses and is one of the primary means that we use to gather information from our surroundings. More than 75% of the information we receive about the world around us consists of visual information.
The eye is often compared to a camera. Each gathers light and then transforms that light into a "picture." Both also have lenses to focus the incoming light. Just as a camera focuses light onto the film to create a picture, the eye focuses light onto a specialized layer of cells, called the retina.
The human eye is an organ which reacts to light and pressure. As a sense organ, the mammalian eye allows vision. Human eyes help to provide a three dimensional, moving image, normally coloured in daylight. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth. The human eye can differentiate between about 10 million colors[1] and is possibly capable of detecting a single photon.
he sense organs — eyes, ears, tongue, skin, and nose — help to protect the body. The human sense organs contain receptors that relay information through sensory neurons to the appropriate places within the nervous system.
Each sense organ contains different receptors.
General receptors are found throughout the body because they are present in skin, visceral organs (visceral meaning in the abdominal cavity), muscles, and joints.
Special receptors include chemoreceptors (chemical receptors) found in the mouth and nose, photoreceptors (light receptors) found in the eyes, and mechanoreceptors found in the ears.
The eye is composed of a series of lenses and spaces that give focus to images, just as a camera does. It is composed of the vitreous humor, aqueous humor, the crystalline lens, and the cornea, and each of these has its own refraction index (the average being 1.34, because of the content of these tissues).Functions
Pupil. Opens and closes in order to regulate and control the amount of light.
Iris. Controls light level similar to the aperture of a camera.
Sclera. Protects the outer coat.
Cornea. A thin membrane which provides 67% of the eye's focusing power.
Crystalline lens. ...
Conjunctive. ...
Aqueous humour.
Vitreous humour.
The eye is composed of a series of lenses and spaces that give focus to images, just as a camera does. It is composed of the vitreous humor, aqueous humor, the crystalline lens, and the cornea, and each of these has its own refraction index (the average being 1.34, because of the content of these tissues)
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R3 Stem Cells and Kidney Repair A New Horizon in Nephrology.pptxR3 Stem Cell
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Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
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There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
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Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
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Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
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Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
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Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
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According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
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2. Sense of Vision
a) accessory structures of the eye are those that are not directly related the sense of vision,
but facilitate the physiology of the eyeballs.
- eyebrows – to shade the eyes from sunlight and to prevent perspiration from reaching
the eyes.
- eyelids- to protect the eyes from foreign objects (e.g. dust particles) and to prevent
desiccation (drying) of the eyes by lubricating fluid.
- conjunctiva- a mucous membrane on the inner lining of eyelids, which produces
lubricating and cleansing fluid for the surface of eye.
3. Lacrimal gland- exocrine gland that secretes a dilute saline solution called tears for
moistening the eyes. [ Tears contain mucus, antibodies and antibacterial enzymes that
protect the eye from infections. Emotional tears also contain enzymes that seem to help
reduce stress levels].
4. Anatomy of the Eye
The wall of the eyeball consists of 3 layers of tissue:
I) Fibrous Tunic:
outermost layer, made of fibrous connective tissue with minimal blood vessels.
- contains 2 regions: sclera (a white area that extends from the back of the eye toward
the front) and cornea ( a transparent tissue in the front for allowing light to enter the
eyeball).
II) Vascular Tunic (also called uvea):
- middle layer, made of thin fibrous connective tissue that contains numerous blood
vessels (capillaries).
6. Also contains choroids ( a pigmented membrane in the back to provide nutrition and to
absorb light) and iris (to regulate the amount of light entering the eye by constriction or
dilation)
Also includes specialized structures such as ciliary body (which regulates the shape of
lens), suspensory ligaments (which attach the ciliary body to the lens).
Also includes the Lens ( another transparent tissue that bends the light entering the
eye), and pupil (an opening created by the actions of the iris where a large pupil is
caused by a dilated iris, while a small pupil is created by a constricted iris).
7.
8. III) Sensory Tunic( also called retina ):
- innermost layer, made of specialized nerve tissue.
-contains 2 layers of tissue: an outer pigmented layer ( which absorbs light and
stores vitamin A) and an inner neural layer (that detects light using photoreceptors
and sends nerve impulses to the occipital lobe of cerebrum through the optic nerves.
- 2 types of photoreceptors are found on the neural layer:
Rods ( detect tones of visual images) and cones ( detect colors). These sensory
cells, after being stimulated by visual sensations, send nerve impulses through the
optic nerve ( Nerve II ) to the occipital lobs of cerebrum.
11. The eyes and vision :
The eye is like a camera . the eyes diaphragm is the iris , which changes pupil aperture ,
regulating the amount of light entering.
The curved cornea and the biconvex lens are like a cameras compound lens , refracting
and converging light rays to form inverted images on the light – sensitive retina (film).
The ciliary muscles change lens curvature for sharp focusing ; in a camera , the lens
moves back and forth .
Dynamics of vision :
light which bears the visual image crosses a series of transparent media (refractive)
media where it is focused upon the retinal surface .
12. Refraction
Light rays passing through the
transparent media of different
densities are bent (refraction). The
denseness and curvature of the
medium determines the degree of
refraction .
Refraction is necessary to form a
small – sized inverted image on the
retina (refractory media is the
cornea and lens) .
The lens must thicken to focus on
close objects .
13. Accommodation, Close & Distant vision
Accommodation : As the distant object moves closer , the image moves behind the retina
to keep the image sharply on the retina , the lens accommodates.
Close vision : ciliary muscles contract, lens ligaments (suspensory) relax, and lens
becomes rounder (more convex).
Distant vision : ciliary muscles relax, lens ligaments (suspensory) contract, lens
becomes less convex (concave).
Note : with age, the lens hardens and is less able to accommodate . After age 55 ,
accommodation is no longer possible (presbyopia) , requiring corrective lenses for reading .
14. Pupil constriction : During accommodation , the Iris also constricts to narrow the pupil ,
permitting increased depth of focus. For very close objects external eye muscles move
the eyeball in word (converge) to keep sharp focus.
Convergence : The movement of each eye – ball is controlled by six eye muscles that
allow the eyes to follow a moving object.
16. Eye Muscles
Muscle Innervation Funtion
Superior rectus Oculomotor rotates eye up & in
Inferior rectus Oculomotor rotates eye down & in
Medial rectus Oculomotor rotates eye inwards
Lateral rectus Abducens rotates eye out
Superior oblique Trochlear rotates eye down & out
Inferior oblique Oculomotor rotates eye up & out
17. Near vision
1. Light rays from an object form a blurred image behind the retina .
2. The blurred image signals are sensed by the brain visual center , which activate midbrain
motor center .
3. Corrective motor signals are send to accommodate lens .
4. Parasympathetic fibers release acetylcholine to contract the ciliary muscles, which relax
the lens for sharp focusing , these nerves stimulate the iris to constrict the pupil .
5. Sympathetic fibers release nor epinephrine to stimulate the iris to dilate the pupil .
18. Photoreceptors of the Retina
The retina contains rods and cones – photoreceptor neurons that synapse with bipolar
cells .
Rods are responsible for colorless vision in relatively dim light .
Cones provide color vision and function in day light .
A light sensitive pigment in rods (Rhodopsin) decomposes in the presence of light and
triggers a complex series of reactions that initiate nerve impulses on the optic nerve .
3 sets of cones (Red , blue , green) , provide color vision . each set contains a different
light – sensitive pigment , and each set is sensitive to a different wave length of light. The
color perceived depends on which set or sets of cones are stimulated .
21. Physiology of vision
1. When light strikes the rods it causes photodissociation of Rhodopsin into retinene and
opsin .
This bleaching reaction occurs maximally with a light wave length of 5oo nm .
Photo dissociation is caused by the conversion of the ll-cis form of retinene to the all –
trans form that can not bind to opsin .
2. In the dark , more rhodopsin can be produced , and increased rhodopsin in the rods
makes the eye more sensitive to light.
The rods provide black – and – white vision under conditions of low light intensity . At
higher light intensity , the rods are bleached out and the cones provide color vision.
23. 3. In the dark , a constant movement of Na+ into the rods produces whatis know
as a "dark current" .
In the dark , rhodopsin (R) molecules are stable , signaling Na+ channelsto
stay open. Inflow of Na+ depolarizes the rods and their synapses. This
activates the inhibitory bipolar cells , which exert inhibition over the G-cells
(Ganglion cells) , thus G- cells are quiet in the dark .
25. 4. In the light , decomposition of R molecules signal the Na+ channels to
close. This hyperpolarizes the rods and their synapses , leading to
inhibition of BP- cells . Inhibited BP- cells allow increased activity in the G-
cells and their axons informing the brain cells of the presence of light.
26. Visual Acuity: Retinal fovea centralis
The fovea centralis contains only cones; more
peripheral parts of the retina contain both
cones and rods .
Each cones in the fovea synapses with one
bipolar cell , which in turn synapse with one
ganglion cell .
As a result of this 1:1 ratio of cones to bipolar
cells, visual acuity is high in the fovea but
sensitivity to low light levels is lower than in
other regions of the retina .
27. Neural processing of visual information
Photoreceptor neural (Rods & cones) , transmit impulses to bipolar cells , which in turn
send signals to Ganglion cells (some bipolar cells are inhibitory and have no axons).
Visual fields: The right half of the visual field is projected to the left half of the retina of each
eye .
a. The left half of the left retina sends fibers to the left lateral Geniculate body of the
thalamus .
b. The left half of the Right retina also sends fibers to the left lateral geniculate body . This is
because these fibers decussate in the optic chiasma .
28.
29.
30. Visual fields
The left lateral geniculate body thus
receives input from the left half of
the retina of both eyes,
corresponding to the right half of the
visual field, the right lateral
geniculate receives information
about the left half of the visual field .
31. Ganglion cells (axon) form the optic verve fibers which converge in the optic disc where
they exit the eye forming the optic nerve .
The inner fibers of each eye (medial fibers) decussate at the optic chiasma , the
temporal fibers travel on the same side (ipsilateral) .
The direct crossed fibers then synapse in the geniculate body and are called optic tracts
.
A small number of fibers synapse in the superior quadrigeminal bodies and control
pupillary reflexes .
From the lateral genticulate body a diverging bundle of fibers (optic radiation) terminate
in the occipital lobe where vision reaches consciousness , (primary visual cortex) .
Other impulses o to the brain stem for various visual reflex.
32.
33. From the primary visual cortex (pvc) , visual signals follow along serial and parallel
pathways to higher visual areas , in the occipital , parietal and temporal cortex. Temporal
pathway involves color and form perception , while parietal pathway analyze motion .
Neurons in the pvc do not respond to illuminated spots but to features of stimuli , such as
lines , edges and bars .
Cells responding to stationary stimuli are called simple cells .
Cells responding to more complex stimuli such as moving bars are called complex cells .
Complex cells receive input from simple cells while sending output to other cortical or sub-
cortical centers.
34. Simple and complex cells responding to a particular orientation are arranged in
orientation columns running perpendicular to the cortical surface . The orientation columns
are placed side by side across the cortex in such a way that those receiving input from one
eye alternate with those connected to the other eye (ocular dominance columns) .
35. Sterescopic Vision
• Stereoscopic vision provides perception of distance
and depth .
• Stereoscopic vision occurs because of the
formation of two slightly different retinal images
that the brain superimposes and intercepts as one
image in three dimensions .
• Note : A one – eyed person uses relative sizes and
positions of familiar objects to judge distance and
depth.
36. Sense Of Hearing
a) The gross anatomy of the human ear includes the outer ear (consists of auricle and external
auditory meatus), middle ear (consists of tympanic membrane and auditory ossicles [malleus ,
incus, and stapes] and inner ear ( consists of cochlea, 3 semicircular canals and the
vestibulocochlear nerve).
b) The outer ear is responsible for transferring sound waves from the environment to the middle
ear.
c) The middle ear is responsible for amplifying sound waves into strong signals for the hearing
receptors to detect.
d) The inner ear is responsible for using mechanoreceptors to detect stimuli for hearing (in
cochlea) and equilibrium (in semicircular canals), and send the nerve impulses through the
vestibulocochlear nerve (Nerve VIII) to the brain.
e) the middle ear also contains the Eustachian tube (auditory tube) that connects with the
pharynx for equalizing air pressure in the skull.
38. External ear:
Auricle (pinna) : collects and directs sound waves to move the tympanic membrane
External auditory canal (meatus) : leads sound waves from Auricle to tympanic membrane
.
Function : collecting and channeling sound waves into the ear canal .
Middle ear:
Tympanic membrane: Elastic structure which vibrates with sound waves connected with
Auditory ossicles; 3 small bones – malleus , Incus, and stapes which conduct vibrations to
oval window of inner ear.
Tympanic cavity : Air spaces within temporal bone containing middle ear structures .
Eustachian tube : communicates middle ear with pharynx .
Muscle: tensor tympani stapedius protect inner ear from loud sounds .
Function: conduct and amplifies vibrations through the action of 3 bones
39.
40. Internal ear:
Osseous labyrinth: cavity within temporal bone shaped like themembranous labyrinth .
Membranous labyrinth: series of delicate channels containing endolymph/ receptors .
Perilymph : fluid between osseous and membraneous labyrinth. Leads sound to cochlea .
Endolymph : fluid within membraneous labyrinth. Its movement stimulates hair cells (stereocilia) .
Vestibule : portion of labyrinth containing cristae and maculae (head position , movement) .
Cochlea : snail – like region containing sound receptors (cochlear organ).
Function : sound wave transduction
42. Sound waves are characterized by frequency (cycles / sec or Hertz) and
amplitude.
Sound frequency = Pitch
Amplitude = Loudness or intensity .
43. The ears outer , middle , and inner parts perform the functions of collecting , amplifying
and transducing sound energy , respectively .
The outer ears pinna and ear canal funnel sound waves onto the eardrum, causing it to
vibrate .
The ear – drum vibration is amplified 20- fold through the lever action of the middle ears
ossicles (malleus, Incus, stapes) , and differential vibrating surfaces of the eardrum and
the inner ears oval window .
Stapes movement displaces the oval window and subsequently the basilar membrane of
the inner ears cochlea , generating frequency-dependent traveling waves in the cochlea .
The hair cells of the cochlea transduce sound waves into nerve impulse.
45. Sound transmission in the cochlea
The basilar membrane supporting the
organ of corti runs along the cochlea’s
length , dividing it into 2 chambers : an
upper scala vestibule and a lower scala
tympani. A thin membrane running
above the organ of corti creates a
middle chamber, the scala media .
The vestibule and tympanic chambers
are filled with perilymph fluid , and
communicate at the apex .
46. The media chamber contains endolymph
, which bathes the organ of corti and its
hair cells . The oval and round windows
at the 2 ends of the perilymph
respectively absorb and release the
sound waves and maintain perilymph in
a compressed state .
47. Cochlear hair cells are innervated by
auditory fibers .
Oval window vibration sets up
traveling waves in the perilymph and
endolymph , which causes the basilar
membrane to vibrate .
The vibration deforms the stereocilia
on hair cells , resulting in receptor
potentials that are synaptically
transmitted to the auditory nerve fibers
, triggering nerve impulses.
48. The organ of corti consists of the pillar of corti and Hair cells that are located on the
supporting cells of the basilar membrane.
The middle – ear ossicles vibrate the cochlea's oval window .
This sets up traveling waves in the perilymph of the cochlea vibrating the basilar
membrane .
High Hz sounds occurs at the cochlea's base , vibrating the narrow stiff basilar membrane
of the basal cochlea .
Low HZ sounds shift toward the apical cochlea , vibrating its wide, loose membrane .
The basilar membrane vibration induce receptor potentials in the Hair cells of the
corresponding cochlear region .
49. The Hair cells act as true auditory receptors , and make synaptic contact with auditory
nerve terminals .
Auditory fibers from different cochlear regions converge to form the auditory nerve , along
with the vestibular nerve (cranial nerve VII)
Auditory fibers of the cranial nerve VII ascend to medulla oblongata , midbrain, and
thalamus and are interpreted in the temporal lobes of the cerebrum .
Note : from thalamus , nerve fibers project to the auditory cortex of the temporal lobe,
some auditory cortex neurons , respond to high tones , some to low tones .
* In human , these auditory areas communicate with higher order cortical areas serving in
language and speech functions .
50. Steps in the generation of sensory impulses from
the ear
1. Sound waves enter the external auditory meatus .
2. Waves of changing pressure causes the tympanic membrane to vibrations coming from sound
wave source .
3. Auditory ossicles amplify and transmit vibrations to the and of the stapes .
4. Movement of the stapes at the oval window transmit vibrations to the perilymph in the scala
vestibule .
5. Vibrations pass through the vestibular membrane and enter the endolymph of the cochlear duct
.
6. Different frequencies of vibration in endolymph move specific regions of the basilar membrane ,
thus stimulating specific sets of receptors cells (hair cells).
51. 7. As receptor cell becomes depolarized ; its membrane become more permeable to
Ca++ ions .
8. In the presence of Ca++ ions , vesicles at the base of receptors cell release
neurotransmitter .
9. Neurotransmitter stimulates the ends of nearby sensory neurons .
10. sensory impulses are triggered on fibers of the cochlear branch of the
vestibulocochlear nerve .
11. Auditory impulses travel into medulla oblongata , midbrain , and thalamus , and are
interpreted in the temporal lobes of the cerebrum .
52. Physiology of sound processing & reception
Sound collected by pinna transported through external auditory meatus sets tympanic
membrane in motion vibration of malleus incus stapes vibration of oval window fluid wave
formed by vibration of oval window travels scala vestibule scala tympani sets basilar layer in
motion Different portions vibrate according to pitch hair cells bend against tectorial membrane
Action potential vestibulocochlear nerve medulla oblongata midbrain thalamus temporal lobes
of cerebrum .
53. Sense of equilibrium
a) Detected by mechanoreceptors in the semicircular canals to help maintain body posture
and body stability.
b) Nerve impulses generated by the receptors in semicircular canals can ales are
transmitted by the vestibular nerve to Nerve VIII, and the signals will be processed by the
brain. The inner ears vestibular apparatus detects changes in the heads (and body) position
in space , signaling the brain motor centers to adjust posture and maintain balance .
54. Equilibrium
1) 3 semicircular canals , which respond to rotational acceleration , in head motion (
dynamic balance).
Vestibular apparatus
2) saccule and utricle (macular organs) , which Respond to head tilting and linear
acceleration (static balance).
Note : saccule and utricle are also know as the otolith organs , covered by a gelatinous
layer containing small calcite crystals (otoliths) . The otoliths are covered by a fluid .
56. Linear acceleration (static balance)
1. The maculae are the sensory organs in both the saccule and the utricle .
2. Each macula consists of Hair cells covered by a gelatinous layer containing small calcite
crystals (otoliths) . The otoliths are covered by a fluid .
3. Horizontal or vertical acceleration of the head in space exerts a stronger pull on the
otoliths , which are denser than the surrounding fluid .
4. This causes the otoliths to displace the stereocilia of the Hair cells and change their
receptor potential (bending stereocilia) .
5. This will stimulate the fibers of the vestibular nerve (which are attached to the Hair cells) to
increase their nerve impulses according to the intensity of displacement .
57.
58. Rotational acceleration (dynamic balance)
The semicircular canals are fluid – filled tubes . During any rotational movement of the
head at least one canal will be active.
Each canal has an ampulla , containing its sensory organ (crista ampullaris) The crista
ampullaris contains hair cells whose stereocilia are embedded in the gelatinous cupula .
When the head begins to rotate in a particular direction , the canal fluid initially lags behind
, which shears the cupula (which is moving with the canal wall) .
This causes the stereocilia to bend in the opposite direction .
This activates the Hair cells , causing the vestibular nerve fibers of cranial nerve VII to
increase its signals to the brain to initiate motor reflexes in the opposite direction to keep
balance.
59. Vestibulospinal reflexes
The vestibular apparatus senses positional changes , and send impulses to brain via the
vestibulocochlear nerve .
In the medulla , the vestibular unclei ; receive these signals and send them to the
cerebellum .
The cerebellum issues appropriate directions to the vestibular nuclei ; which signal the
midbrain motor centers to execute proper reflex movements of the head, and eye muscles .
These reflexes help maintain a steady image of the surrounding objects on retina . The
vestibule nuclei also signal the spinal motor nuclei to activate the appropriate postural
muscles .These reflexes help maintain balance .
Note : spinning and then stopping abruptly can cause oscillatory movements of the eye
(Nystagmus) .