This document defines a high risk newborn as one with a greater chance of morbidity within the first 28 days of life, regardless of birth weight or gestational age. It identifies high risk factors such as low birth weight, multiple births, high birth order, artificial feeding, and infection. The goals of care for high risk newborns are outlined as perinatal prevention, resuscitation, evaluation and management, monitoring, and family centered care. Assessment methods including initial assessment, APGAR scoring, clinical assessment, transitional assessment, behavioral assessment, physical assessment, and reflex assessment are discussed.