The document discusses the physiology of vision. It describes the main mechanisms of vision including light incidence, transduction, transmission of visual sensations, and visual perceptions. It then discusses the anatomy of the eye, including the cornea, lens, retina, and aberrations like spherical aberration. It also covers topics like accommodation, visual processing in the retina, visual pathway to the brain, and analysis in the primary and secondary visual cortices.
The visual pathway/visual system is the part of central nervous system which gives organisms the ability to process visual detail , as well as enabling the formation of several non-image photo response functions.
It detects interprets information from visible light to build a representation of the surrounding environment .
The visual system carries out a number of complex tasks , including the reception of light and the formation of monocular representations; the buildup of a nuclear binocular perception from a pair of two dimensional projections ; the identification and categorization of visual objects ; assessing distances to and between objects and guiding body movements in relation to the objects seen.
The visual pathway/visual system is the part of central nervous system which gives organisms the ability to process visual detail , as well as enabling the formation of several non-image photo response functions.
It detects interprets information from visible light to build a representation of the surrounding environment .
The visual system carries out a number of complex tasks , including the reception of light and the formation of monocular representations; the buildup of a nuclear binocular perception from a pair of two dimensional projections ; the identification and categorization of visual objects ; assessing distances to and between objects and guiding body movements in relation to the objects seen.
This ppt file belongs to Mr. Yonas Akalu one of my best instructors ...
Vision is by far the most used of the five senses and is one of the primary means that we use to gather information from our surroundings. More than 75% of the information we receive about the world around us consists of visual information.
The eye is often compared to a camera. Each gathers light and then transforms that light into a "picture." Both also have lenses to focus the incoming light. Just as a camera focuses light onto the film to create a picture, the eye focuses light onto a specialized layer of cells, called the retina.
The human eye is an organ which reacts to light and pressure. As a sense organ, the mammalian eye allows vision. Human eyes help to provide a three dimensional, moving image, normally coloured in daylight. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth. The human eye can differentiate between about 10 million colors[1] and is possibly capable of detecting a single photon.
The lacrimal apparatus is the physiological system containing the orbital structures for tear production and drainage. It consists of: The lacrimal gland, which secretes the tears, and its excretory ducts, which convey the fluid to the surface of the human eye;it is a serous gland located in lacrimal fossa.
ocular anatomy fluid system glaucoma lens cataract phototransduction field visual acuity ocular movement errors of refraction light reflex accommodation corneal reflex visual pathway and its lesions
structure of eye ball,eyeball is a specialized sense organ that helps us to understand our environment. It is a sensory unit composed of three parts: receptor, sensory pathway, and a brain center
The main parts of the human eye are The Conjunctiva,
Sclera,Choroid,
Cornea, Iris, Pupil,
Anterior Chamber,
Posterior Chamber, Aqueous humor, Lens, Vitreous humor, Retina,Macula and Optic nerve.
The retina is the sensory membrane that lines the inner surface of the back of the eyeball. It's composed of several layers, including one that contains specialized cells called photoreceptors.
Photoreceptor cells take light focused by the cornea and lens and convert it into chemical and nervous signals which are transported to visual centers in the brain by way of the optic nerve.
In the visual cortex of the brain (which, ironically, is located in the back of the brain), these signals are converted into images and visual perceptions.
This ppt file belongs to Mr. Yonas Akalu one of my best instructors ...
Vision is by far the most used of the five senses and is one of the primary means that we use to gather information from our surroundings. More than 75% of the information we receive about the world around us consists of visual information.
The eye is often compared to a camera. Each gathers light and then transforms that light into a "picture." Both also have lenses to focus the incoming light. Just as a camera focuses light onto the film to create a picture, the eye focuses light onto a specialized layer of cells, called the retina.
The human eye is an organ which reacts to light and pressure. As a sense organ, the mammalian eye allows vision. Human eyes help to provide a three dimensional, moving image, normally coloured in daylight. Rod and cone cells in the retina allow conscious light perception and vision including color differentiation and the perception of depth. The human eye can differentiate between about 10 million colors[1] and is possibly capable of detecting a single photon.
The lacrimal apparatus is the physiological system containing the orbital structures for tear production and drainage. It consists of: The lacrimal gland, which secretes the tears, and its excretory ducts, which convey the fluid to the surface of the human eye;it is a serous gland located in lacrimal fossa.
ocular anatomy fluid system glaucoma lens cataract phototransduction field visual acuity ocular movement errors of refraction light reflex accommodation corneal reflex visual pathway and its lesions
structure of eye ball,eyeball is a specialized sense organ that helps us to understand our environment. It is a sensory unit composed of three parts: receptor, sensory pathway, and a brain center
The main parts of the human eye are The Conjunctiva,
Sclera,Choroid,
Cornea, Iris, Pupil,
Anterior Chamber,
Posterior Chamber, Aqueous humor, Lens, Vitreous humor, Retina,Macula and Optic nerve.
The retina is the sensory membrane that lines the inner surface of the back of the eyeball. It's composed of several layers, including one that contains specialized cells called photoreceptors.
Photoreceptor cells take light focused by the cornea and lens and convert it into chemical and nervous signals which are transported to visual centers in the brain by way of the optic nerve.
In the visual cortex of the brain (which, ironically, is located in the back of the brain), these signals are converted into images and visual perceptions.
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4. Optic system of eyeball
Cornea -allows light to enter the eyeball.
Aqueous humor -fills anterior and
posterior chambers.
Crystalline lens –transparent, elastic
biconvex lens.
Vitreous body -a transparent gel
enclosed by vitreous membrane, fills
eyeball behind lens.
Retina
5.
6. Aberrations and
astigmatism
Spherical aberration light rays pass through peripheral parts of the
eye lens and are not focused sharply. -because of more refractive
power in central part of lens. Due to this effect object loose clear
contour.
Chromatic aberration Unequal deviation of light rays of different
wavelengths. - focusing of different colours at different distances
behind lens. -object get rainbow contour.
Diffractive aberration occur in case of small object interfere to light
rays in clear mediums of eyeball (for instance foreign body). - point
object looks like rounded by gray and white circles.
Astigmatism is an errors of refraction in which light rays do not all
come to a common focal point. Oblong shape of cornea or lens
causes it. So, cylindrical lenses may correct this defect of
refraction.
7. Accommodation and its
regulation
Accommodation is adjustment of eye lens
for various distances. Relaxation of ciliary
muscle cause decrease of refractive power
of eye lens and provides clear vision for long
distance.
Parasympathetic influence to ciliary muscle
controls it. In case of parasympathetic
stimulation of ciliary muscle, it
contracts, lens ligament relax, lens get more
spherical, refractive power increases and
eye can see clear near objects.
8.
9. Age peculiarities
In newborn anatomical axis of eyeball is shorter, comparing to
adults. – complex neural pathways not developed.
In infant- Structure and visual development go side by side by
delicate balance between visual stimulation in right amount at
right time and development of brain. –eye protects the immature
brain from level of stimulation that it cannot cope with initially by-
short size, hypermetropia, immature fovea, absence of binocular
stereoscopic vision, limited peripheral field of view. Also excess
sleeping most of the time, slow communication due to absence of
fatty myelin sheath contributes.
In old age lens of eye loose elasticity. So this condition, when lens
become non-accommodating, called presbiopia. Corrected by
bifocal glasses with upper segment focused for far-seeing and
lower segment focusing for near-seeing.
10. Initiation of vision
Inadequate stimuli Adequate stimuli
• Produce glowing • Formed by the
sensation called- visible part of
PHOSPHENES electromagnetic
• Pressure phosphenes radiation spectrum
• Movement
phosphenes
• Electrical
phosphenes
• Radiation
phosphenes
11. Physiological peculiarities of pigmented
layer and photoreceptors.
Light falls on retina on inner side i.e. on inner limiting
membrane.
Central portion of macula called fovea centralis.
This is composed entirely of cones. It is a minute
area of 1 mm in center of retina. It provides acute
and detailed vision.
Pigmented layer of retina contains black
pigment, i.e. melanin. It prevents light reflection
through the globe of eyeball and stores vitamin A.
12. Photochemical reactions in
retina
Outer segment of
photoreceptors contain
photochemicals. Inner segment
contains nucleus, synaptic body
and other organelles.
Photochemicals are light-
sensitive chemicals that
decompose on exposure to light
and excite nerve fibers leading
from eye to central nervous
system.
Rhodopsin is present in rods.
Scotopsin and 11-cis-retinal
compose it. Iodopsin is
photochemical pigment of
cones. Photopsin and 11-cis-
retinal compose it.
13. Rhodopsin cycle: rhodopsin under the influence of light
converts to prelumirhodopsin – lumirhodopsin –
metaphodopsin I - metaphodopsin II – opsin –
rhodopsin. Metarhodopsin II converts also to all-
transretinal (vitamin A) – (isomerase’s action) – II cis-
retinal – rhodopsin.
(Activate transducin)
14. Rhodopsin
Metarhodopsin II
Activation of transducin
Activation of phoshpdiasterase
Decreased intracellular cGMP
Hyperpolarization
15. Neurophysiology of vision
Genesis of visual impulse in photoreceptors
Processing and transmission in retina
Processing and transmission in visual pathway
Analysis in visual cortex
3-part system hypothesis of visual perception
16. Physiological activities in the retinal cells
Neurotransmitters
Glutamine – by rods and cones.
Amacrine cells produce 5 different inhibitory
transmitters, GABA, glycine, dopamine, Ach,
Indolamine.
Cholinesterase by muller , Horizontal, Amacrine
and Ganglion cells.
Carbonic anhydrase from cones and RPE.
17. Cellular activities
Horizontal cells: Enhance visual contrast
by lateral inhibition, hence processing
of spatial information.
-when a minute stroke of light strikes
the retina, the central most area is
excited while the area around is
inhibited.
Bipolar cells: stimulated by
hyperpolarization of photoreceptors.
• Two different types, provide opposing
excitatory (depolarizing bipolar cells)
and inhibitory signals in response to
stimulation by light.
• Second mechanism of lateral inhibition
by centre-surround antagonism. (on-cell
and off cells)
18. Amacrine cells:
• Negative feedback arrangement to subsequent
response to be projected onto ganglion cells.
• Receive information at the synapse of bipolar cell
axon and ganglion cell dendrites.
• Temporal processing of this information at other
end of bipolar cells.
• TYPES of function
1. Direct pathway for rod vision
2. Onset-activated cells
3. Offset-activated cells
4. Illumination change sensitive cells
5. Direction sensitive cells
19. Ganglion cells: transmit signal as action potential
to the brain.
• Three groups-
• W-ganglion- small, 40% of total, broad fields in
retina, excitation from rods, detect direction
movement anywhere in the field.
• X-ganglion- medium diameter, 55% of total, small
field, colour vision. Sustained response.
• Y- ganglion cells- largest, 5%, very broad dendritic
field, respond to rapid eye movement or rapid
change in light intensity. Transient response.
20. Transmission of vision
Impulses from retina pass to optic nerve – optic chiasma (fibers from
nasal halves of retina cross to opposite side) – optic tracts – synapse
in lateral genicular body – geniculocalcarine fibers – pass through
optic radiation or geniculocalcarine tract – primary visual cortex in
calcarine fissure or medial aspect of occipital lobe.
21. Lateral geniculate body
Functions: relay station, to gate the
transmission of signals.
Layer 1,2:
• large cells, called magnocellular
pathways
• Input from
Y-ganglion cells
• Very rapid conduction
• Colour blind system
Layer 3-6:
• Parvocellular
• Input from
X- ganglion cells
• Colour vision
• Moderate velocity.
22. Other connections of
optic tract
In addition to lateral genicular body, fibers
from optic tract also pass to:
- suprachiasmatic nucleus of hypothalamus
for controlling circadian rhythms;
- pretectal nuclei – for control of fixation of
eyes on objects of importance and for
pupillary light reflex;
- superior colliculus – for control of bilateral
simultaneous movements of two eyes;
- pulvinar – forms secondary visual pathway.
Corpus callosum causes exchange of visual
information between right and left
hemispheres.
23. Pupillary reflexes
When light pass into eye, pupil contracts. In
darkness pupil dilates. This is Direct pupillary light
reflex, which helps to adaptation to light
conditions.
Reflex arc: light receptors - optic nerve- optic
tract - pretectal area - Edinger-Westphal nucleus -
parasympathetic fibers of n. oculomotorius (from
n. trigeminus) - n. ciliaris - m. sphincter pupillae -
decrease of pupillary diameter.
Consensual pupillary light reflex: reaction of eye
pupil to light irritation of opposite eye. It is possible
due to diverging of nerve fibers from one
pretectal nucleus to both Edinger-Westphal
nuclei.
24. Analysis of visual impulse
in visual cortex
Primary visual cortex
•Brodmann’s area 17/ visual area 1
•Grossly striated appearance
Secondary visual cortex
•Includes visual association areas
•Lie ant, sup, inf to 1’ visual cortex
•Brodmann area 18,19/visual area II,III
25. Primary visual cortex – 6 distinct layers
• Layers I,II,III- thin, contain pyramidal cells
• Layer IV- thickest, contains stellate cells
• -further subdivided in a, b, c alpha and c beta
• Layer V,VI relatively thin
• Connections
• Geniculate afferents- rapidly conducted
signals from Y-ganglional cells terminate
in layer IV c alpha
• From X ganglion cells to layer IVa and IVc
• Subcortical connections –
• upper part of layer VI to magnocellular
layers
• -lower part of layer VI project to
parvocellular layers.
• Corticocortical connections-
• From layers II and III
26. Receptive fields of visual cortex
Three receptive field types
1. Simple cells- mainly in layer IV
• Respond to bars of light, lines or edges only when
oriented in particular direction
• Most effective orientation of stimulus is k/a
receptive field axis orientation
• Parallel bands of On and Off areas
2. Complex cells – above and below layer IV
• Preferred orientation of linear stimulus
• No on and off regions
• Less dependent upon location of stimulus
• Plays role specially when stimulus is moving
• SO SIMPLE AND COMPLEX CELLS TOGETHER ARE
K/A FEATURE DETECTORS.
27. 3. Hypercomplex cells –
• In cortical layers II and III
• All features of complex cells but require the line
stimulus to be of specific length
• So specific role in shape and angle detection
28. colour blobs
• Primary areas for deciphering colours
• Special column like areas interspersed among the
primary visual columns.
• Respond specifically to colour signals
29. Three part system hypothesis of
visual perceptions
First system-
movement,
location and
spatial
organization
Second system-
color perception
Third system-
shapes
perception
30. Visual perceptions
Sensations from stimulation of retina by light.
Four types-
• Light sense - Faculty to perceive light in all
gradations of intensity.
-light minimum
• Form sense - to perceive the shape of object in
outer world.
-max at fovea/ cones.
• Contrast sense- ability to perceive slight changes in
luminance between regions not separated by sharp
borders.
• Colour sense -ability to distinguish between
different colours as excited by light of different
wavelengths.
31. Theories of colour
perception
According to Young-Helmholtz theory
there are three types of cones for
three fundamental colours: cones for
red colour contain erythrolab; cones
for green colour contain chlorolab;
cones for blue colour contain
cyanolab.
Do not explain why dichromats see
yellow.
Do not explain complementary colour
after images.
32. According to Hering theory there are couples of
opponent colours:
Spectrally opponents viz Green – red; yellow – blue.
Spectrally non opponent white – black.
Subcortical neurons perceive it due to on- and off-
centers mechanism.
Both theories combined explain the colour vision
system. Trichromatic operates at receptor level and
the signals are recorded into the opponent process
form by higher level neural system of colour vision
processing.
33. Disorders of colour perception
. There are three fundamental colours: Red, Green and
Blue.
Clinical presentations:
•Total colour blindness
•Partial colour blindness
•Red–green
•Dichromacy (protanopia and
deuteranopia)
•Anomalous trichromacy (protanomaly
and deuteranomaly)
•Blue–yellow
•Dichromacy (tritanopia)
•Anomalous trichromacy (tritanomaly)