2. WATER-SOLUBLE VITAMINS, THEIR SOURCES,
DAILY REQUIREMENTS AND DEFICIENCY
DISEASES
B1 Thiamine
Absorbed in
proximal
small
intestne
Beri-Beri
1.2–1.8
mg/day
Cereals,
grains
and yeast
B2
Riboflavin or
lactoflavin
Proximal small
intestine
Cracked
lips, red lips,
inflammation
of the lining
of mouth and
tongue, mouth
ulcers, cracks
at the corner
of
mouth
(angular
cheilosis and
sore throat
1–2 mg/
day
(0.5–0.6
mg/1000
Kcal
Milk, liver and
kidney
Niacin Niacin Stomach Pellagra
12–20 mg
(5.5-6.5
mg/1000
Kcal
Rice polish,
yeast, liver,
poultry
and green
vegetables
B1 Thiamine
Absorbed in
proximal small Beri-Beri
1.2–1.8
mg/day
Cereals,
grains
3. Contd…
B6
Pyridoxine,
Pyridoxal,
Pyridoxami
ne
Jejunum
and
ileum
Cheilosis,
glossits,
hypodermic
anemia
1–2 mg
Egg, fish,
green leaf,
vegetables,
and cereals
Pantothen
ic acid
Pantothenic
acid
Jejunum
Headache,
fatigue,
impaired
motor
activity,
muscle
cramps and
gastrointesti
nal
disturbances
5–10 mg
Yeast liver,
egg, potato,
whole
cereals
legumes.
Biotn
Proximal
small
intestne
Mild
dermatts,
nausea, loss
of appette,
muscular
pain
and anemia
15–30 µg
Rice polish,
whole
cereals,
milk, Yeast,
and organ
meat such
as liver and
kidney
4. Contd…
Folic acid
Pteroylgluta
mic
acid
Mainly in
jejunum
Macrocytc
(megaloblas
tc)
anemia,
accompanie
d by
leukopenia [
In
pregnancy
may
lead to
neural
tube
defects
150–300
µg
Green leafy
vegetables
such as
spinach and
cabbage,
yeast, liver
and
kidney
B12
Extrinsic
factors
of castle,
Cyano
cobalamin
Stomach
Methylmalon
ic
aciduria
1–3 µg
Liver, kidney,
egg, fsh, and
milk
Vitamin C
Ascorbic
acid
Cells Scurvy
40–60 mg
day
Amla, citrus
fruit, green
chillies,
guava