The integumentary system is the organ system that protects the body from various kinds of damage, such as loss of water or abrasion from outside. The system comprises the skin and its appendages (including hair, scales, feathers, hooves, and nails). The integumentary system has a variety of functions; it may serve to waterproof, cushion, and protect the deeper tissues, excrete wastes, and regulate temperature, and is the attachment site for sensory receptors to detect pain, sensation, pressure, and temperature. In most terrestrial vertebrates with significant exposure to sunlight, the integumentary system also provides for vitamin D synthesis.
The integumentary system is the organ system that protects the body from various kinds of damage, such as loss of water or abrasion from outside. The system comprises the skin and its appendages (including hair, scales, feathers, hooves, and nails). The integumentary system has a variety of functions; it may serve to waterproof, cushion, and protect the deeper tissues, excrete wastes, and regulate temperature, and is the attachment site for sensory receptors to detect pain, sensation, pressure, and temperature. In most terrestrial vertebrates with significant exposure to sunlight, the integumentary system also provides for vitamin D synthesis.
The tongue is a muscular organ in the mouth of most vertebrates that manipulates food for mastication and is used in the act of swallowing. It has importance in the digestive system and is the primary organ of taste in the gustatory system.
1.picture of tongue
2. Cadaveric picture of tongue
3. Introduction of tongue
4. function of tongue
5. presenting parts
6. parts of tongue
7. diagram of tongue
8. Base of tongue
9. Dorsal surface of tongue
10. Papillae
11. Histology of papillae
12. Ventral surface of tongue
13 ventral surface
14. lateral margin of tongue
15. root of tongue
16. Muscles of tongue
17.Muscles diagram
18. Genioglossus
19.Hyoglossus
20. Superficial relation of hyoglossus
21. Deep relation of hyoglossus
22.Styloglossus
23.Palatoglossus
24.Intrinsic muscles of tongue
25.Muscles altering the shape of the tongue
26.Nerve supply of tongue
27.Sensory nerve supply of tongue
28.motor supply- diagram
29. sensory supply- diagram
30. Taste sensation part
31. Lymphatic Drainage
32.Pecularities of lymphatic drainage
33. Applied Anatomy
34. Tongue Tie
35.Bifid tongue
36. Lingual thyroid & Thyroglossal cyst
37.glossitis
38.Carcinoma of the tongue
39. Identify the structures
40. Thank you
Introduction
Development of tongue.
Anatomy of tongue
Arterial supply & nerve supply of tongue.
functions of the tongue.
Pathologic consideration of tongue.
Conclusion.
References
INTRODUCTION
Tongue is a muscular organ
Situated in the floor of the mouth
FUNCTION
Taste
Speech
Mastication
Deglutition
EXTERNAL FEATURES
Tongue has
A Root
A tip
A body
ROOT
Is attached to the mandible and soft palate above and hyoid bone below.
These attachments prevent the swallowing of the tongue.
In between the 2 bones it is related to the geniohyoid and mylohyoid muscles.
TIP
Of the tongue forms the anterior free end which lies behind the upper incisor teeth.
BODY
Has
A curved upper surface or dorsum
An inferior or ventral surface MUSCLES OF THE TONGUE
Middle fibrous septum divides the tongue into right and left halves.
Intrinsic muscles
Superior longitudinal
Inferior longitudinal
Transverse
Vertical
Extrinsic muscles
Genioglossus
Hyoglossus
Styloglossus
Palatoglossus
The tongue is a muscular organ in the mouth of most vertebrates that manipulates food for mastication and is used in the act of swallowing. It has importance in the digestive system and is the primary organ of taste in the gustatory system.
1.picture of tongue
2. Cadaveric picture of tongue
3. Introduction of tongue
4. function of tongue
5. presenting parts
6. parts of tongue
7. diagram of tongue
8. Base of tongue
9. Dorsal surface of tongue
10. Papillae
11. Histology of papillae
12. Ventral surface of tongue
13 ventral surface
14. lateral margin of tongue
15. root of tongue
16. Muscles of tongue
17.Muscles diagram
18. Genioglossus
19.Hyoglossus
20. Superficial relation of hyoglossus
21. Deep relation of hyoglossus
22.Styloglossus
23.Palatoglossus
24.Intrinsic muscles of tongue
25.Muscles altering the shape of the tongue
26.Nerve supply of tongue
27.Sensory nerve supply of tongue
28.motor supply- diagram
29. sensory supply- diagram
30. Taste sensation part
31. Lymphatic Drainage
32.Pecularities of lymphatic drainage
33. Applied Anatomy
34. Tongue Tie
35.Bifid tongue
36. Lingual thyroid & Thyroglossal cyst
37.glossitis
38.Carcinoma of the tongue
39. Identify the structures
40. Thank you
Introduction
Development of tongue.
Anatomy of tongue
Arterial supply & nerve supply of tongue.
functions of the tongue.
Pathologic consideration of tongue.
Conclusion.
References
INTRODUCTION
Tongue is a muscular organ
Situated in the floor of the mouth
FUNCTION
Taste
Speech
Mastication
Deglutition
EXTERNAL FEATURES
Tongue has
A Root
A tip
A body
ROOT
Is attached to the mandible and soft palate above and hyoid bone below.
These attachments prevent the swallowing of the tongue.
In between the 2 bones it is related to the geniohyoid and mylohyoid muscles.
TIP
Of the tongue forms the anterior free end which lies behind the upper incisor teeth.
BODY
Has
A curved upper surface or dorsum
An inferior or ventral surface MUSCLES OF THE TONGUE
Middle fibrous septum divides the tongue into right and left halves.
Intrinsic muscles
Superior longitudinal
Inferior longitudinal
Transverse
Vertical
Extrinsic muscles
Genioglossus
Hyoglossus
Styloglossus
Palatoglossus
Nose is the part of respiratory system. External nose and nasal cavity. The visible portion that project from the face. It's skeleton is mainly cartilaginous ( small bony contributions are present). The superior bony part of the nose, including it's root, is covered by thin skin. Nasal septum has bony part vomer bone . Sometimes the deviation is so severe that the nasal septum is in contact with the lateral wall of the nasal cavity and often obstruct breathing or except snoring........................
Boundaries of the nasal cavity and often do I get to know about you guys are present for the nasal cavity and often do I need some of you thank god I was in my heart and soul mate is the nasal cavity and I can is wider than the roof. Inferior concha is the longest and border and is formed by an independent bone covered by
Dentist in pune.(BDS. MDS) - Dr. Amit T. Suryawanshi. Nose & Paranasal sinuses.All Good Things
Dentist in pune. (BDS. MDS) - Dr. Amit T. Suryawanshi. Seminar- Nose & Paranasal sinuses.
Email ID- amitsuryawanshi999@gmail.com
Contact -Ph no.-9405622455
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The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
2. TREYresearch
TheNose
• Consists of the external nose and the nasal cavity both of which are divided by a septum into
right and left halves.
• External Nose; has two elliptical orifices called the nostrils, which are separated from each
other by the nasal septum.
• The lateral margin, the ala nasi, is rounded and mobile.
• The framework of the external nose is made up above by the nasal bones, the frontal
processes of the maxillae, and the nasal part of the frontal bone.
• Below, the framework is formed of plates of hyaline cartilage
• Blood Supply of the External Nose; The skin of the external nose is supplied by branches of
the ophthalmic and the maxillary arteries.
• The skin of the ala and the lower part of the septum are supplied by branches from the facial
artery.
• Nerve Supply of the External Nose; The infratrochlear and external nasal branches of the
ophthalmic nerve (CN V) and the infraorbital branch of the maxillary nerve (CN V).
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3. TREYresearch
NasalCavity
• The nasal cavity extends from the nostrils in front to the posterior nasal apertures or
choanae behind, where the nose opens into the nasopharynx.
• The nasal vestibule is the area of the nasal cavity lying just inside the nostril.
• The nasal cavity is divided into right and left halves by the nasal septum.
• The septum is made up of the septal cartilage, the vertical plate of the ethmoid, and
the vomer.
• Walls of the Nasal Cavity
• Each half of the nasal cavity has a floor, a roof, a lateral wall, and a medial or septal
wall.
• Floor; The palatine process of the maxilla and the horizontal plate of the palatine
bone.
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NasalCavity
• Roof; narrow and is formed anteriorly beneath the bridge of the nose by the nasal
and frontal bones, in the middle by the cribriform plate of the ethmoid, located
beneath the anterior cranial fossa, and posteriorly by the downward sloping body of
the sphenoid
• Lateral Wall; has three projections of bone called the superior, middle, and inferior
nasal conchae.
• The space below each concha is called a meatus.
• Sphenoethmoidal Recess is a small area above the superior concha; It receives the
opening of the sphenoid air sinus.
• Superior Meatus; lies below the superior concha; It receives the openings of the
posterior ethmoid sinuses.
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NasalCavity
• Middle Meatus; lies below the middle concha.
• It has a rounded swelling called the bulla ethmoidalis that is formed by the middle
ethmoidal air sinuses, which open on its upper border.
• A curved opening, the hiatus semilunaris, lies just below the bulla.
• The anterior end of the hiatus leads into a funnel-shaped channel called the
infundibulum, which is continuous with the frontal sinus.
• The maxillary sinus opens into the middle meatus through the hiatus semilunaris.
• Inferior Meatus; lies below the inferior concha and receives the opening of the lower
end of the nasolacrimal duct, which is guarded by a fold of mucous membrane
• Medial Wall; formed by the nasal septum.
• The upper part is formed by the vertical plate of the ethmoid and the vomer.
• The anterior part is formed by the septal cartilage. The septum rarely lies in the midline,
thus increasing the size of one half of the nasal cavity
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MucousMembraneoftheNasalCavity
• The vestibule is lined with modified skin and has coarse hairs.
• The area above the superior concha is lined with olfactory mucous membrane and contains
nerve endings sensitive to the reception of smell.
• The lower part of the nasal cavity is lined with respiratory mucous membrane.
• A large plexus of veins in the submucous connective tissue is present in the respiratory region.
• Function of Warm Blood and Mucus of Mucous Membrane
• The presence of warm blood in the venous plexuses serves to heat up the inspired air as it
enters the respiratory system.
• The presence of mucus on the surfaces of the conchae traps foreign particles and organisms in
the inspired air, which are then swallowed and destroyed by gastric acid.
• Nerve Supply of the Nasal Cavity
• The olfactory nerves from the olfactory mucous membrane ascend through the cribriform plate
of the ethmoid bone to the olfactory bulbs.
• The nerves of ordinary sensation are branches of the ophthalmic division (V1) and the maxillary
division (V2) of the trigeminal nerve
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MucousMembraneoftheNasalCavity
• Blood Supply to the Nasal Cavity
• The arterial supply to the nasal cavity is from branches of the maxillary artery.
• The most important branch is the sphenopalatine artery.
• The sphenopalatine artery anastomoses with the septal branch of the superior labial
branch of the facial artery in the region of the vestibule.
• The submucous venous plexus is drained by veins that accompany the arteries.
• Lymph Drainage of the Nasal Cavity
• The lymph vessels draining the vestibule end in the submandibular nodes.
• The remainder of the nasal cavity is drained by vessels that pass to the upper deep
cervical nodes.
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ParanasalSinuses
• Cavities found in the interior of the maxilla, frontal, sphenoid, and ethmoid bones.
• They are lined with mucoperiosteum and filled with air; they communicate with the nasal
cavity through relatively small apertures.
• The maxillary and sphenoidal sinuses are present in a rudimentary form at birth; they enlarge
appreciably after the eighth year and become fully formed in adolescence.
• Drainage of Mucus and Function of Paranasal Sinuses
• The mucus produced by the mucous membrane is moved into the nose by ciliary action of the
columnar cells.
• Drainage of the mucus is also achieved by the siphon action created during the blowing of the
nose.
• The function of the sinuses is to act as resonators to the voice; they also reduce the weight of
the skull.
• When the apertures of the sinuses are blocked or they become filled with fluid, the quality of
the voice is markedly changed.
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MaxillarySinus
• Pyramidal in shape and located within the body of the maxilla behind the skin of the
cheek
• The roof is formed by the floor of the orbit, and the floor is related to the roots of the
premolars and molar teeth.
• The maxillary sinus opens into the middle meatus of the nose through the hiatus
semilunaris
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FrontalSinuses
• The two frontal sinuses are contained within the frontal Bone.
• They are separated from each other by a bony septum.
• Each sinus is roughly triangular, extending upward above the medial end of the
eyebrow and backward into the medial part of the roof of the orbit.
• Each frontal sinus opens into the middle meatus of the nose through the
infundibulum.
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ParanasalSinuses
• Sphenoidal Sinuses
• The two sphenoidal sinuses lie within the body of the sphenoid bone.
• Each sinus opens into the sphenoethmoidal recess above the superior concha.
• Ethmoid Sinuses;
• Anterior, middle, and posterior and they are contained within the ethmoid bone,
between the nose and the orbit.
• They are separated from the latter by a thin plate of bone so that infection can readily
spread from the sinuses into the orbit.
• The anterior sinuses open into the infundibulum; the middle sinuses open into the
middle meatus, on or above the bulla ethmoidalis; and the posterior sinuses open into
the superior meatus.
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CrossingofAirandFoodPathwaysinthePharynx
• It is in the pharynx that the air and food pathways cross.
• This is made possible by the presence of the soft palate, which serves as a flap valve.
• This flap shuts off the mouth from the oropharynx, for example, during the process of
chewing food so that breathing may continue unaffected.
• The completely raised soft palate can shut off the nasopharynx from the oropharynx,
thus preventing food entering the nasopharynx in swallowing.
• When it is desirable to direct the maximum amount of air in and out of the larynx, the
soft palate is raised to direct air through the mouth rather than the narrow cavities of
the nose.
• Such an arrangement permits the expectoration of mucus from the respiratory
system through the mouth.
• It also allows the maximum expiration of air through the mouth as in the use of wind
instruments such as the trumpet.
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TheLarynx
• An organ that provides a protective sphincter at the inlet of the air passages and is
responsible for voice production.
• It is situated below the tongue and hyoid bone and between the great blood vessels
of the neck and lies at the level of the fourth, fifth, and sixth cervical vertebrae.
• It opens above into the laryngeal part of the pharynx, and below is continuous with
the trachea.
• The larynx is covered in front by the infrahyoid strap muscles and at the sides by the
thyroid gland.
• The framework of the larynx is formed of cartilages that are held together by
ligaments and membranes, moved by muscles, and lined by mucous membrane.
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CartilagesoftheLarynx
• Thyroid cartilage: This is the largest cartilage of the larynx and consists of two
laminae of hyaline cartilage that meet in the midline in the prominent V angle (Adam’s
apple)
• The posterior border extends upward into a superior cornu and downward into an
inferior cornu.
• On the outer surface of each lamina is an oblique line for the attachment of muscles.
• Cricoid cartilage: This cartilage is formed of hyaline cartilage and shaped like a signet
ring, having a broad plate behind and a shallow arch in front.
• The cricoid cartilage lies below the thyroid cartilage, and on each side of the lateral
surface is a facet for articulation with the inferior cornu of the thyroid cartilage.
• Posteriorly, the lamina has on its upper border on each side a facet for articulation
with the arytenoid cartilage.
• All these joints are synovial.
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CartilagesoftheLarynx
• Arytenoid cartilages: There are two arytenoid cartilages, which are small and pyramid
shaped and located at the back of the larynx.
• They articulate with the upper border of the lamina of the cricoid cartilage.
• Each cartilage has an apex above that articulates with the small corniculate cartilage, a
base below that articulates with the lamina of the cricoid cartilage, and a vocal process
that projects forward and gives attachment to the vocal ligament.
• A muscular process that projects laterally gives attachment to the posterior and lateral
cricoarytenoid muscles.
• Corniculate cartilages: Two small conical-shaped cartilages articulate with the
arytenoid cartilages; They give attachment to the aryepiglottic folds.
• Cuneiform cartilages: These two small rod-shaped cartilages are found in the
aryepiglottic folds and serve to strengthen them
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CartilagesoftheLarynx
• Epiglottis: This leaf-shaped lamina of elastic cartilage lies behind the root of the
tongue.
• Its stalk is attached to the back of the thyroid cartilage.
• The sides of the epiglottis are attached to the arytenoid cartilages by the aryepiglottic
folds of mucous membrane.
• The upper edge of the epiglottis is free.
• The covering of mucous membrane passes forward onto the posterior surface of the
tongue as the median glossoepiglottic fold; the depression on each side of the fold is
called the vallecula.
• Laterally, the mucous membrane passes onto the wall of the pharynx as the lateral
glossoepiglottic fold.
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MembranesandLigamentsoftheLarynx
• Thyrohyoid membrane: This connects the upper margin of the thyroid cartilage to the
hyoid bone.
• In the midline, it is thickened to form the median thyrohyoid ligament.
• The membrane is pierced on each side by the superior laryngeal vessels and the
internal laryngeal nerve, a branch of the superior laryngeal nerve.
• Cricotracheal ligament: This connects the cricoid cartilage to the first ring of the
trachea.
• Quadrangular membrane: This extends between the epiglottis and the arytenoid
cartilages.
• Its thickened inferior margin forms the vestibular ligament, and the vestibular
ligaments form the interior of the vestibular folds.
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• Cricothyroid ligament:
• The lower margin is attached to the upper border of the cricoid cartilage.
• The superior margin of the ligament, instead of being attached to the thyroid
cartilage, ascends on the medial surface of the thyroid cartilage.
• Its upper free margin, composed almost entirely of elastic tissue, forms the important
vocal ligament on each side.
• The vocal ligaments form the interior of the vocal folds (vocal Cords).
• The anterior end of each vocal ligament is attached to the thyroid cartilage, and the
posterior end is attached to the vocal process of the arytenoid cartilage.
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MembranesandLigamentsoftheLarynx
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InletoftheLarynx
• Looks backward and upward into the laryngeal part of the pharynx.
• The opening is wider in front than behind and is bounded in front by the epiglottis,
laterally by the aryepiglottic fold of mucous membrane, and posteriorly by the
arytenoid cartilages with the corniculate cartilages.
• The cuneiform cartilage lies within and strengthens the aryepiglottic fold and
produces a small elevation on the upper border.
• The Piriform Fossa
• A recess on either side of the fold and inlet.
• It is bounded medially by the aryepiglottic fold and laterally by the thyroid cartilage
and the thyrohyoid membrane.
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LaryngealFolds
• Vestibular Fold; A fixed fold on each side of the larynx.
• It is formed by mucous membrane covering the vestibular ligament and is vascular and pink in
color.
• Vocal Fold (Vocal Cord); A mobile fold on each side of the larynx and is concerned with voice
production.
• It is formed by mucous membrane covering the vocal ligament and is avascular and white in color.
• The vocal fold moves with respiration and its white color is easily seen when viewed with a
laryngoscope.
• The gap between the vocal folds is called the rima glottides or glottis.
• The glottis is bounded in front by the vocal folds and behind by the medial surface of the
arytenoid cartilages.
• The glottis is the narrowest part of the larynx and measures about 2.5 cm from front to back in
the male adult and less in the female.
• In children, the lower part of the larynx within the cricoid cartilage is the narrowest part.
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CavityoftheLarynx
• Extends from the inlet to the lower border of the cricoid cartilage, where it is
continuous with the cavity of the trachea. It is divided into three regions:
• The vestibule, which is situated between the inlet and the vestibular folds
• The middle region, which is situated between the vestibular folds above and the vocal
folds below
• The lower region, which is situated between the vocal folds above and the lower
border of the cricoid cartilage below
• Sinus of the Larynx; a small recess on each side of the larynx situated between the
vestibular and vocal folds.
• It is lined with mucous membrane.
• Saccule of the Larynx; a diverticulum of mucous membrane that ascends from the
sinus.
• The mucous secretion lubricates the vocal cords.
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MusclesoftheLarynx
• Extrinsic Muscles
• These muscles move the larynx up and down during swallowing.
• Many of these muscles are attached to the hyoid bone, which is attached to the
thyroid cartilage by the thyrohyoid membrane.
• It follows that movements of the hyoid bone are accompanied by movements of the
larynx.
• Elevation: The digastric, the stylohyoid, the mylohyoid, the geniohyoid, the
stylopharyngeus, the salpingopharyngeus, and the palatopharyngeus muscles.
• Depression: The sternothyroid, the sternohyoid, and the omohyoid muscles.
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MusclesoftheLarynx
• Intrinsic Muscles; Two muscles modify the laryngeal inlet:
• Narrowing the inlet: The oblique arytenoid muscle
• Widening the inlet: The thyroepiglottic muscle
• Five muscles move the vocal folds (cords):
• Tensing the vocal cords: The cricothyroid muscle
• Relaxing the vocal cords: The thyroarytenoid (vocalis) muscle
• Adducting the vocal cords: The lateral cricoarytenoid muscle
• Abducting the vocal cords: The posterior cricoarytenoid muscle
• Approximates the arytenoid cartilages: The transverse arytenoid muscle
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MovementsoftheVocalFolds(Cords)
• Depend on the movements of the arytenoid cartilages, which rotate and slide up and
down on the sloping shoulder of the superior border of the cricoid cartilage.
• The rima glottidis is opened by the contraction of the posterior cricoarytenoid, which
rotates the arytenoid cartilage and abducts the vocal process.
• The elastic tissue in the capsules of the cricoarytenoid joints keeps the arytenoid
cartilages apart so that the posterior part of the glottis is open.
• The rima glottidis is closed by contraction of the lateral cricoarytenoid, which rotates
the arytenoid cartilage and adducts the vocal process.
• The posterior part of the glottis is narrowed when the arytenoid cartilages are drawn
together by contraction of the transverse arytenoid muscles.
• The vocal folds are stretched by contraction of the cricothyroid
• muscle.
• The vocal folds are slackened by contraction of the vocalis, a part of the thyroarytenoid
muscle
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• Movements of the Vocal Folds with Respiration
• On quiet inspiration, the vocal folds are abducted and the rima glottidis is triangular in shape
with the apex in front.
• On expiration, the vocal folds are adducted, leaving a small gap between them.
• On deep inspiration, the vocal folds are maximally abducted and the triangular shape of the
glottis becomes a diamond shape because of the maximal lateral rotation of the arytenoid
cartilages.
• Sphincteric Function of the Larynx There are two sphincters in the larynx: one at the inlet and
another at the rima glottidis.
• The sphincter at the inlet is used only during swallowing.
• As the bolus of food is passed backward between the tongue and the hard palate, the larynx
is pulled up beneath the back of the tongue.
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MovementsoftheVocalFolds(Cords)
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• The inlet of the larynx is narrowed by the action of the oblique arytenoid and
aryepiglottic muscles.
• The epiglottis is pulled backward by the tongue and serves as a cap over the laryngeal
inlet.
• The bolus of food, or fluids, then enters the esophagus by passing over the epiglottis
or moving down the grooves on either side of the laryngeal inlet, the piriform fossae.
• In coughing or sneezing, the rima glottidis serves as a sphincter.
• After inspiration, the vocal folds are adducted, and the muscles of expiration are
made to contract strongly.
• As a result, the intrathoracic pressure rises, and the vocal folds are suddenly
abducted.
• The sudden release of the compressed air will often dislodge foreign particles or
mucus from the respiratory tract and carry the material up into the pharynx, where
the material is either swallowed or expectorated.
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MovementsoftheVocalFolds(Cords)
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MovementsoftheVocalCords(Folds)
• In the Valsalva maneuver, forced expiration takes place against a closed glottis. In
abdominal straining associated with micturition, defecation, and parturition, air is
often held temporarily in the respiratory tract by closing the rima glottidis.
• After deep inspiration, the rima glottidis is closed.
• The muscles of the anterior abdominal wall now contract, and the upward movement
of the diaphragm is prevented by the presence of compressed air within the
respiratory tract.
• After a prolonged effort, the person often releases some of the air by momentarily
opening the rima glottidis, producing a grunting sound.
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VoiceProductionintheLarynx
• The intermittent release of expired air between the adducted vocal folds results in
their vibration and in the production of sound.
• The frequency, or pitch, of the sound is determined by changes in the length and
tension of the vocal ligaments.
• The quality of the voice depends on the resonators above the larynx, the pharynx,
mouth, and paranasal sinuses.
• The quality of the voice is controlled by the muscles of the soft plate, tongue, floor of
the mouth, cheeks, lips, and jaws.
• Normal speech depends on the modification of the sound into recognizable
consonants and vowels by the use of the tongue, teeth, and lips.
• Vowel sounds are usually purely oral with the soft palate raised so that the air is
channeled through the mouth rather than the nose.
• Speech involves the intermittent release of expired air between the adducted vocal
folds.
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• Singing a note requires a more prolonged release of the expired air between the
adducted vocal folds.
• In whispering, the vocal folds are adducted, but the arytenoid cartilages are
separated; the vibrations are given to a constant stream of expired air that passes
through the posterior part of the rima glottidis.
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VoiceProductionintheLarynx
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MucousMembraneoftheLarynx
• Lines the cavity and is covered with ciliated columnar epithelium.
• On the vocal cords, where the mucous membrane is subject to repeated trauma during
phonation, the mucous membrane is covered with stratified squamous epithelium.
• Nerve Supply of the Larynx; Sensory Nerves
• Above the vocal cords: The internal laryngeal branch of the superior laryngeal branch of
the vagus
• Below the level of the vocal cords: The recurrent laryngeal nerve.
• Motor Nerves; All the intrinsic muscles of the larynx except the cricothyroid muscle are
supplied by the recurrent laryngeal nerve.
• The cricothyroid muscle is supplied by the external laryngeal branch of the superior
laryngeal branch of the vagus.
• Blood Supply of the Larynx
• Upper half of the larynx: The superior laryngeal branch of the superior thyroid artery
• Lower half of the larynx: The inferior laryngeal branch of the inferior thyroid artery
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TheTrachea
• A mobile cartilaginous and membranous tube.
• It begins as a continuation of the larynx at the lower border of the cricoid cartilage at
the level of the 6th cervical vertebra.
• It descends in the midline of the neck.
• In the thorax, the trachea ends at the carina by dividing into right and left principal
(main) bronchi at the level of the sternal angle (opposite the disc between the 4th
and 5th thoracic vertebrae).
• The fibroelastic tube is kept patent by the presence of U-shaped cartilaginous bar
(rings) of hyaline cartilage embedded in its wall.
• The posterior free ends of the cartilage are connected by smooth muscle, the
trachealis muscle.
• The mucous membrane of the trachea is lined with pseudostratified ciliated columnar
epithelium and contains many goblet cells and tubular mucous glands.
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TheTrachea
• Relations of the Trachea in the Neck
• Anteriorly: Skin, fascia, isthmus of the thyroid gland (in front of the second, third, and
fourth rings), inferior
• thyroid vein, jugular arch, thyroidea ima artery (if present), and the left brachiocephalic
vein in children, overlapped by the sternothyroid and sternohyoid muscles.
• Posteriorly: Right and left recurrent laryngeal nerves and the esophagus.
• Laterally: Lobes of the thyroid gland and the carotid sheath and contents.
• Nerve Supply of the Trachea; The sensory nerve supply is from the vagi and the
recurrent laryngeal nerves.
• Blood Supply of the Trachea; The upper two thirds is supplied by the inferior thyroid
arteries and the lower third is supplied by the bronchial arteries.
• Lymph Drainage of the Trachea; Into the pretracheal and paratracheal lymph nodes
and the deep cervical nodes
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