This document discusses system suitability requirements for precision in analytical methods. It explains that replicate injections of a standard are used to calculate the relative standard deviation (RSD) and the number of injections required depends on the RSD limit. A formula is provided to calculate the maximum permitted RSD for assays based on the number of replicate injections and other parameters. Tables show the maximum RSD values corresponding to different numbers of injections and concentration limits. Instructions are given on calculating t-distribution values and degrees of freedom needed for the RSD calculation.