syncope in children , vasovagal syncope , fainting in children , causes of syncope in children , how to manage syncope in children , cardiac syncope , differnetial diagnosis of syncope , approach to syncope
Approach to Syncope in Children (Pediatric Syncope).pptxJwan AlSofi
Approach to Syncope in Children (Pediatric Syncope), includes:-
Introduction
Differential diagnosis of syncope
Syncope vs vertigo vs Presyncope vs light-headedness.
Comparison of Clinical Features of Syncope and Seizures
Neurocardiogenic (Vasovagal) syncope
MECHANISMS and Causes of Syncope
Cardiac causes of syncope
Life-threatening causes of syncope
Red Flags in Evaluation of Patients With Syncope
Non-cardiac causes of loss of consciousness.
Noncardiac Causes of Syncope
Differentiating Features for Causes of Syncope
EVALUATION of syncope:- History, Examination,Treatment.
Summary
this lecture explains Syncope which is a transient loss of consciousness from many points: the definition, causes, next step, history and physical examination from evidence based resources as the UpToDate and the European society of cardiology guidelines 2018.
social cognition domains and impairment.pptxDoha Rasheedy
Social cognition refers to a set of neurocognitive processes underlying the individuals’ ability to “make sense of others’ behavior” as a “crucial prerequisite of social interaction” The different psychological processes by which we perceive, interpret, and process social information about ourselves and others. These processes allow people to understand social behavior and respond in ways that are appropriate and beneficial Social cognitive impairments are a prominent concern, or even a core facet, of several neurodegenerative (e.g., behavioral variant of frontotemporal dementia), neuropsychiatric (e.g., schizophrenia, major depressive disorder, and bipolar disorder), and neurodevelopmental (e.g., autism spectrum disorder and attention deficit hyperactivity disorder) conditions, and often occur after acute brain damage (e.g., traumatic brain injury and stroke). Moreover, such deficits are critical predictors of functional outcomes because they affect the ability to create and maintain interpersonal relationships, thereby removing their benefits in everyday life Social cognitive disturbances might be relatively subtle and harder to detect informally. Structured social cognitive assessment is, therefore , mandated.
Basic of geriatrics and internal medicine for physiotherapistDoha Rasheedy
collection of lectures for physiotherapy undergraduate students including notes of common health issues (frailty, sarcopenia, osteoporosis, neuropsychiatric issues, constipation, metabolic syndrome and its components, orthostatic hypotension, CLD, CKD, anemia, immobilization, dizziness, falls, fatigue) and how to handle in practice.
summary of age related changes and geriatric pharmacology, safe analgesic prescription in elderly
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
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Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
1. 1
SYNCOPE
• Syncope is a sudden loss of consciousness and postural tone resulting from a
decrease in cerebral blood flow. The loss of consciousness is brief, and
recovery is rapid and spontaneous.
• Syncope itself is not a diagnosis but rather a symptom of an underlying
disorder.
EPIDEMIOLOGY:
• The incidence of syncope increases dramatically with advancing age.
• The incidence of syncope per 1000 person-years increases from 6 in the
sixth decade of life to 11 in the seventh decade. The incidence is 17 and 20
for men and women, respectively, in the eighth decade.
• Almost 50% of emergency room visits for syncope are made by persons 65
years of age or older.
• Subjects with cardiac, neurologic, or unknown causes of syncope have a
worse prognosis than subjects without syncope. Interestingly, subjects with
vasovagal, orthostatic, or medications as a cause of their syncope did not
have a decreased survival compared with subjects without syncope.
PATHOPHYSIOLOGY:
• The underlying pathophysiology leading to syncope is inadequate
oxygenation of the cerebral cortex and reticular activating system, resulting
in loss of consciousness.
Risk factors for increased syncope in elderly:
• Having more underlying chronic conditions and being on more medications
than younger adults.
• age-related physiological changes that increase their syncope risk:
1. Atherosclerosis (impairing dilation of cerebral blood vessels in the
face of reduced blood flow)
2. Increased endothelin production (increasing vasoconstriction of
cerebral arterioles)
3. Left ventricular dysfunction, due to long standing hypertension and/or
heart disease (causing decreased cardiac output)
4. Cardiac valvular disease (increasing the likelihood of arrhythmias
and heart block)
2. 2
5. Blunting of autonomic responses, baroreceptor reflex (predisposing
the person to orthostatic hypotension)
CAUSES:
• They fall into these general categories: neurally mediated (reflex) causes,
orthostatic hypotension, cardiac causes, central nervous system diseases, and
psychiatric disorders.
EVALUATION:
A) HISTORY:
3. 3
• History from the patient and an eyewitness, if present, is needed to
distinguish syncope from other entities such as dizziness, vertigo, drop
attacks, coma, and seizure.
• Historical features are often sufficient to distinguish syncope from seizures.
Seizures are associated with blue face (or not pale), frothing at the mouth,
tongue biting, disorientation, aching muscles, sleepiness after the event, and
duration of unconsciousness of more than 5 minutes. On the other hand,
symptoms associated with syncope are sweating or nausea before the event
and being oriented after the event. The best discriminatory symptom is
disorientation after the episode, which often signifies a seizure.
4. 4
• Vasovagal or neurocardiogenic syncope is the most common type of neurally
mediated syncope; it includes the common faint. Typically, a situation
involving prolonged standing, emotional distress, or exertion in a warm
environment causes peripheral venous pooling and a drop in blood return to
the heart. As the heart recognizes a sudden decrease in preload, it tries to
compensate by contracting harder. The quick increase in contraction
activates mechanoreceptors in the ventricles that start a reflex mechanism
causing the central nervous system to stimulate vasodilation and
bradycardia. As the drop in cardiac output becomes more profound, syncope
may occur.When suspecting a neurally mediated syncope, look for
associated symptoms of nausea and/or vomiting, prolonged standing, hot
environments, and unpleasant situations. You should be cautious to not
assume this diagnosis in patients with known heart disease or repetitive
episodes of syncope.
• Carotid sinus syndrome: when manual stimulation of the carotid sinus can,
in susceptible individuals, stimulate neurally mediated syncope.
• Orthostatic hypotension: is a drop in arterial pressure that occurs when an
individual moves to an upright position. Typically, the autonomic nervous
system rapidly compensates for this by increasing the venous tone in the
legs; when this system fails, syncope may occur. When the circulating blood
volume is depleted, as in dehydration, orthostatic hypotension, and syncope
may occur even with appropriate autonomic compensation. This diagnosis
should be considered in individuals who are on medications that can
predispose to hypotension, who have reason due to illness or blood loss to be
dehydrated, or have autonomic insufficiency from a neurological disorder
such as Parkinsonism. A typical case occurs soon after standing up
• Cardiac syncope occurs when reduction in cardiac functioning by
arrhythmia, death of myocardium, or outflow obstruction leads to decreased
blood flow to the brain. Several studies have shown an increase in overall
mortality and sudden death among patients with cardiac syncope compared
to patients with syncope from other causes. A cardiac cause should be
considered when syncope is preceded by palpitations or chest pain, or when
it occurs during exertion. Patients with known severe structural heart disease
should be considered to have cardiac syncope until proven otherwise.
5. 5
• Cerebrovascular disease is a rare but plausible cause of syncope. Most
transient ischemic attacks or strokes do not cause loss of consciousness, but
occasionally this can occur. There is a low yield to use of neurological
testing in the evaluation of individuals with syncope unless it is directed at
those with neurological findings on initial evaluation.
• Psychiatric causes should be considered in patients with repetitive syncope
of unknown origin after cardiac causes have been effectively ruled out. They
are more common in younger patients. Prodromal symptoms, such as
dizziness, are common. Several hypotheses exist regarding the connection
between psychiatric disorders and syncope. Hyperventilation can increase
susceptibility to neurally mediated syncope. There is also a term called
pseudo- syncope, which has been used to describe patients with syncope of
unknown but presumed psychiatric origin, who have no pathological
findings on exam and documented syncope without any change in blood
pressure or pulse.
The history can identify symptoms and situations surrounding
syncope that can help diagnose three common etiologies, neurally
mediated (vasovagal), orthostasis, and drug related syncope.
B) PHYSICAL EXAMINATION:
• .In detection of orthostatic hypotension, supine blood pressure and heart rate
should be measured after the patient has been lying down for at least 5
minutes. Standing measurements should be obtained immediately and for at
least 3 minutes. Sitting blood pressures are not reliable for detection of
orthostatic hypotension.
• Several cardiovascular findings are crucial diagnostically. Differences in the
pulse intensity and blood pressure (generally >20 mmHg) in the two arms
are suggestive of aortic dissection or subclavian steal syndrome.
• Special focus on cardiovascular examination for aortic stenosis,
• Carotid Bruits, carotid massage.
• Neurological examination.
The evaluation of the patient with syncope involves the parallel process of
seeking a specific diagnosis and ruling out cardiac causes. The initial history,
6. 6
examination, and electrocardiogram are sufficient in most cases to rule in or out
cardiac disease
C) Further evaluation: Should focus on the following issues:
(1) arrhythmia detection, (2) tilt testing, and (3) multiple abnormalities
causing symptoms.
Arrhythmia Detection
Electrocardiogram or a rhythm strip
Ambulatory holter monitoring
Electrophysiologic studies
External loop recorders
Implantable loop recorders.
Cardiac stress testing is rarely diagnostic in the evaluation of syncope. It should be
considered in patients who have syncope during exertion or experience chest pain
associated with syncope.
Tilt table testing:
Can be useful as confirmatory tests for neurally mediated syncope.
The procedure involves baseline measurement of blood pressure and heart rate
while supine, then quickly bringing the patient to an upright position by tilting to
approximately 60 degrees. A foot board is in place for support. The patient is then
kept in the tilted position for 45 minutes to observe for syncope or presyncopal
symptoms while continuing to monitor heart rate and blood pressure. Some protocols
include giving isoproterenol or nitroglycerin after the patient has been asymptomatic
in the tilted position for 10 to 15 minutes followed by further monitoring. If syncope
symptoms occur during testing and correlate with a quick drop in blood pressure or
pulse rate, it is considered a positive test. Likewise, if syncope occurs without a
change in vital signs, a neurally mediated syncope is less likely and other etiologies
should be reconsidered
Carotid massage:
CSM is performed as follows:
1. Confirm that no carotid bruits are present and that there is no known significant cerebral
vascular disease. If bruits are present, or the patient is at high risk for atherosclerotic
disease, consider carotid Doppler ultrasound to evaluate for significant plaque.
2. Have the patient supine, on continuous ECG monitoring and beat-to-beat blood pressure
monitoring. An IV line should be in place, and atropine and transcutaneous pacing available.
3. Turn the patient’s head to the left in the supine position and find the maximum impulse in
the right carotid artery at the level of the thyroid cartilage. Use two fingers, firmly press
down,and massage longitudinally for 5 to 10 seconds. Wait a few minutes and repeat on the
left carotid sinus. Repeat in the head-up tilt position if symptoms do not occur in the supine
position.
7. 7
A positive cardioinhibitory result is present if a cardiac pause (asystole) of 3 seconds or
longer occurs during or immediately after CSM; a positive vasopressor result is present if the
systolic blood pressure drops 50 mmHg or more, and is accompanied by symptoms.
Multiple abnormalities causing symptoms:
According to the published recommendations for syncope evaluation, neuroimaging and
EEG can be limited to patients with symptoms or signs of acute stroke or seizure.
Initial laboratory blood tests rarely yield diagnostically helpful information. Hypoglycemia,
hyponatremia, hypocalcemia, or renal failure is found in 2% to 3% of patients, but in most
cases appears to result in seizures rather than syncope .
8. 8
MANAGEMENT:
Management Considerations
o Management issues include hospitalization decision, treatment selection, and patient
instructions and education.
o the treatment largely depends on the cause of syncope.
o First-time syncope in patients without known or suspected heart disease usually
warrants the reduction of risk factors for further syncope. This includes reducing
polypharmacy and medication misuse, treating underlying illness, and education
regarding avoidance of triggers.
o Individuals with cardiac disease deserve a more aggressive effort in establishing an
etiology of syncope and treatment of cardiac causes. Identifying and treating
structural heart disease will help reduce the risk of recurrent syncope.
When to Hospitalize
o Consider hospitalization of older patients with multiple comorbidities when the etiology seems
multifactorial and a monitored environment is needed to sort it out.
o Hospitalize patients with known or suspected potentially fatal arrhythmias.
o Hospitalize patients with unknown etiology of syncope when cardiac disease is known or
suspected by initial evaluation.
9. 9
o Hospitalize when the cause is identified and requires admission (e.g., myocardial infarction or
pulmonary embolism
the treatment according to the cause of syncope
Neurally Mediated Syncope
o Because of potential side effects, treatment should be reserved for elderly patients with
frequent or disabling symptoms. Because psychiatric illnesses (especially depression and
anxiety) probably lead to vasovagal reactions, screening for the psychiatric illnesses
noted above should be performed. Treatment of the psychiatric illness often results in
resolution of recurrent syncope.
o The most commonly used drugs are beta-blockers (e.g., metoprolol 50–200 mg/day,
atenolol 25–200 mg/day, and propranolol 40–160 mg/day), which may inhibit the
activation of cardiac mechanoreceptors by decreasing cardiac contractility. Other drugs
include anticholinergic drugs, such as transdermal scopolamine one patch every 2 to 3
days, disopyramide (200 –600 mg/day), paroxetine (20–40 mg/day) theophylline (6–12
mg/ kg/day), and measures to expand volume (increased salt intake, custom fitted
counter pressure support garments from ankle to waist, and fludrocortisone acetate at
0.1–1 mg per day).
Orthostatic Hypotension
o The initial approach to treatment of orthostatic hypotension is to ensure adequate salt
and volume intake and to discontinue drugs that cause orthostatic hypotension. Patients
with orthostatic hypotension should be advised to raise the head of the bed at night, to
rise from bed or chair slowly, and avoid prolonged standing. Compressive stockings
applied up to thigh level may help decrease venous pooling. Frequent small feedings
may be helpful for patients with marked postprandial hypotension.
o Pharmacologic agents of potential benefit include fludrocortisone (0.1–1 mg/day), in
conjunction with increased salt intake. Various agents have been used including
midodrine, ephedrine, phenylephrine, and others.
Patient Instructions and Education
o Issues in patient education include instructions in prevention of syncope,
nonpharmacologic treatment, and restriction of activities. Many patients with vasovagal
syncope have precipitating factors or situations that should be identified, and the patient
instructed to avoid these situations. Common triggers include prolonged standing,
venipuncture, large meals, and heat (such as hot baths or sunbathing). Additionally,
fasting, lack of sleep, and alcohol intake may predispose to vasovagal syncope and
should be avoided.
o Post exercise vasovagal syncope may occasionally be related to chronic inadequate salt
and fluid replacement. Syncope may be prevented with the use of electrolyte containing
solutions and water in such instances. In other patients exercise may have to be
curtailed.
Finally, do not forget to think of safety issues such as driving, flying, operating heavy
machinery, and risk of injury from falls.