This paper describes the design and fabrication of a novel artificial hand based on a “biomechatronic” and cybernetic approach. The approach is aimed at providing “natural” sensory-motor co-ordination, biomimetic mechanisms, force and position sensors, actuators and control, and by interfacing the hand with the peripheral nervous system.
Different types of electric terminal devices used for transradial and transhumeral, shoulder disarticutaion prosthesis used for external powered prosthesis.
At the end of this presentation, you will be able to understand what is physiotherapy and what kind of robotic devices we use. Those robotic devices have been very helpful but it can be a little challenging for us to utilize all the types of devices. The physiotherapist should know about the devices that he/she uses and have experience with it and that can be a disadvantage of the robotic devices. We have a lot of types of robotic devices for all kinds of disabilities. The patients can have more confidence and be more focused during the sessions. The devices have been an advantage for physiotherapists as well. It helps physiotherapists not to burnout during the sessions. Especially patients with disabilities like difficulty walking or even standing up. The future of physiotherapy and robotic devices is still in progress and let's see what it can bring us.
This paper describes the design and fabrication of a novel artificial hand based on a “biomechatronic” and cybernetic approach. The approach is aimed at providing “natural” sensory-motor co-ordination, biomimetic mechanisms, force and position sensors, actuators and control, and by interfacing the hand with the peripheral nervous system.
Different types of electric terminal devices used for transradial and transhumeral, shoulder disarticutaion prosthesis used for external powered prosthesis.
At the end of this presentation, you will be able to understand what is physiotherapy and what kind of robotic devices we use. Those robotic devices have been very helpful but it can be a little challenging for us to utilize all the types of devices. The physiotherapist should know about the devices that he/she uses and have experience with it and that can be a disadvantage of the robotic devices. We have a lot of types of robotic devices for all kinds of disabilities. The patients can have more confidence and be more focused during the sessions. The devices have been an advantage for physiotherapists as well. It helps physiotherapists not to burnout during the sessions. Especially patients with disabilities like difficulty walking or even standing up. The future of physiotherapy and robotic devices is still in progress and let's see what it can bring us.
Presented by Brad Aiken
Doctor and science-fiction writer Brad Aiken presents on new and upcoming technologies in neurological rehabilitation. Topics include breakthrough advances that can help people recover from stroke, brain injury, and spinal cord injury. Current, cutting-edge technologies will be discussed, as well as likely upcoming advances in this field.
Neurorobotics and Advances in rehabilitation engineeringBhaskarBorgohain4
Advances in robotics,mechatronics,cyborgs and disruptive technologies for heptics, brain machine interfaces and neurorobotics are bringing a sea change to the field of rehabilitation engineering. Carbon fibre cheetah blades, Bionic arms, c legs are helping the amputees to the extent that amputees can now run in competitive sports at the level of summer Olympics.
Shoulder subluxation and Wilmer carrying OrthosisSmita Nayak
The patients having the problem of shoulder subluxation due to brachial plexus injury, hemiplegia or muscle weakness need a biomechanically efficient orthosis to treat the problem as well as maintain the functional position of the limb, in that case, the Wilmer carrying orthosis plays the major role by shifting the center of gravity nearer to the elbow joint that able to place the femoral head inside the acetabulum without displacing the head laterally. This orthosis is better in comparison to the conventional orthosis used for the subluxation like bobathcuff, shoulder cuff, slings, and hemislings.the design of the elbow Wilmer orthosis also varies as per the age of the patients. The design for the child case also available without a locking elbow joint but with a spring that helps the child to do different activities of daily living which enhances the growth of the child. The major problem in Erb's palsy in addition to shoulder subluxation is the associated fail elbow and wrist drop, these problems can be solved by this orthosis by modifying the design on the standard version. The lightweight feature for children which starts from 35 grams to 80 gram makes this design more comfortable and cosmetically appealing.
Design and Analysis of Prosthetic Foot using Additive Manufacturing TechniqueYogeshIJTSRD
Prosthetic feet are designed for an individuals foot at a particular activity level. Prosthetic foot is a style for people that cannot walk, the performance is basically cosmetic. For people who square measure most actively, a prosthetic foot should mimic a traditional foot throughout the act of walking. The fabric for prosthetic feet varies by varied use of foot and by varied application. Wood, plastic and foam are sometimes found in feet designed for people who have low activity levels and need stability. Carbon fiber feet meet the purposeful wants for shock absorption and energy potency, and square measure light weight further. a variety of metals square measure used for prosthetic limbs Al, Titanium, Magnesium, Copper, Steel, and lots of additional. titanium was discovered within the late eighteenth century. Its a typical metal used for medical and engineering applications due to its several favorable properties. its sensible strength to weight quantitative relation, guck strength to density quantitative relation, glorious corrosion resistance, density and its light weight. So, perform static and model analysis on existing prosthetic foot to seek out stresses, total deformation. Then replace the fabric with the 3D printing additive producing technique. And find out the analysis result and compare the prevailing. Then experimental testing may be carried out to validate the result. Mr. Akshay Dashrath Mule | Prof. Dr. P. M. Bagade "Design and Analysis of Prosthetic Foot using Additive Manufacturing Technique" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45044.pdf Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/45044/design-and-analysis-of-prosthetic-foot-using-additive-manufacturing-technique/mr-akshay-dashrath-mule
Prosthetic hand using Artificial Neural NetworkSreenath S
Real Time Moving Prosthetic.
It's an innovative technology,improvising the prosthetic field with the application of Artificial Neural Network technology.Unlike anyother prosthetic hand, this has a Real Time data accquisition system which varies the data set according to the input signal.This is customisable to any amputee. The hardware was developed by simple and easily available materials.We have come up with a new technology in the prosthetic field.
Bionics is an aid to technology that is bridging the gap between human limitation and potential. This presentation deals with the details of bionics and different milestones implemented.
Bionic arm is a revolutionary idea for amputees across the globe. This is as close as we can get to our natural limb. The fundamental point is to make the arm move with our brain unlike previous prosthetic upper limbs
Presented by Brad Aiken
Doctor and science-fiction writer Brad Aiken presents on new and upcoming technologies in neurological rehabilitation. Topics include breakthrough advances that can help people recover from stroke, brain injury, and spinal cord injury. Current, cutting-edge technologies will be discussed, as well as likely upcoming advances in this field.
Neurorobotics and Advances in rehabilitation engineeringBhaskarBorgohain4
Advances in robotics,mechatronics,cyborgs and disruptive technologies for heptics, brain machine interfaces and neurorobotics are bringing a sea change to the field of rehabilitation engineering. Carbon fibre cheetah blades, Bionic arms, c legs are helping the amputees to the extent that amputees can now run in competitive sports at the level of summer Olympics.
Shoulder subluxation and Wilmer carrying OrthosisSmita Nayak
The patients having the problem of shoulder subluxation due to brachial plexus injury, hemiplegia or muscle weakness need a biomechanically efficient orthosis to treat the problem as well as maintain the functional position of the limb, in that case, the Wilmer carrying orthosis plays the major role by shifting the center of gravity nearer to the elbow joint that able to place the femoral head inside the acetabulum without displacing the head laterally. This orthosis is better in comparison to the conventional orthosis used for the subluxation like bobathcuff, shoulder cuff, slings, and hemislings.the design of the elbow Wilmer orthosis also varies as per the age of the patients. The design for the child case also available without a locking elbow joint but with a spring that helps the child to do different activities of daily living which enhances the growth of the child. The major problem in Erb's palsy in addition to shoulder subluxation is the associated fail elbow and wrist drop, these problems can be solved by this orthosis by modifying the design on the standard version. The lightweight feature for children which starts from 35 grams to 80 gram makes this design more comfortable and cosmetically appealing.
Design and Analysis of Prosthetic Foot using Additive Manufacturing TechniqueYogeshIJTSRD
Prosthetic feet are designed for an individuals foot at a particular activity level. Prosthetic foot is a style for people that cannot walk, the performance is basically cosmetic. For people who square measure most actively, a prosthetic foot should mimic a traditional foot throughout the act of walking. The fabric for prosthetic feet varies by varied use of foot and by varied application. Wood, plastic and foam are sometimes found in feet designed for people who have low activity levels and need stability. Carbon fiber feet meet the purposeful wants for shock absorption and energy potency, and square measure light weight further. a variety of metals square measure used for prosthetic limbs Al, Titanium, Magnesium, Copper, Steel, and lots of additional. titanium was discovered within the late eighteenth century. Its a typical metal used for medical and engineering applications due to its several favorable properties. its sensible strength to weight quantitative relation, guck strength to density quantitative relation, glorious corrosion resistance, density and its light weight. So, perform static and model analysis on existing prosthetic foot to seek out stresses, total deformation. Then replace the fabric with the 3D printing additive producing technique. And find out the analysis result and compare the prevailing. Then experimental testing may be carried out to validate the result. Mr. Akshay Dashrath Mule | Prof. Dr. P. M. Bagade "Design and Analysis of Prosthetic Foot using Additive Manufacturing Technique" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd45044.pdf Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/45044/design-and-analysis-of-prosthetic-foot-using-additive-manufacturing-technique/mr-akshay-dashrath-mule
Prosthetic hand using Artificial Neural NetworkSreenath S
Real Time Moving Prosthetic.
It's an innovative technology,improvising the prosthetic field with the application of Artificial Neural Network technology.Unlike anyother prosthetic hand, this has a Real Time data accquisition system which varies the data set according to the input signal.This is customisable to any amputee. The hardware was developed by simple and easily available materials.We have come up with a new technology in the prosthetic field.
Bionics is an aid to technology that is bridging the gap between human limitation and potential. This presentation deals with the details of bionics and different milestones implemented.
Bionic arm is a revolutionary idea for amputees across the globe. This is as close as we can get to our natural limb. The fundamental point is to make the arm move with our brain unlike previous prosthetic upper limbs
Right from stating the basic research problem, collecting vital data and analyzing it everything can be done easily with aid of experts offering help here. Now! You are not even required to choose research technique as experts will decide the most apt and latest technique for your work.
A seasoned F&A professional with 32 years experience having multi-faceted knowledge in F&A domain.Worked in PAN india companies in respectable positions.
Cybernetics is an interdisciplinary study of regulatory systems, their structures, constraints and possibilities. Cybernetics was defined by Norbert Wiener in 1948 as “the scientific study of control and communication in living organism and the machine”. Cybernetics study includes but not limited to artificial learning, adaptation, cognition, convergence, Social Control, efficacy, efficiency, connectivity and communication [1]. It is known from science fiction; technically modified organism with exceptional skills called as cyborgs -it was originated from the term “cybernetic organism”. As a matter of fact, cyborgs that incorporates technical systems with living organism are already reality. For instance, smart machines that spontaneously operate to changing dynamic conditions, computer supported designs and fabrication based on magnetic tomography datasets or surface modifications for enhanced tissue integration that allowed major development in cybernetics technology [2,3].
Artificial eye and its applications in daily lifep23anurag
According to a survey made by World Health Organization
(WHO) in 2023, over 2.2 billion of people are affected by visual
disabilities, it was with a challenge that this project came into
being. It aims at restoring vision to the blind. High-tech advancements in microelectronics, Optoelectronic,
computer science and biomedical engineering are working
together to realize a device for the electrical stimulation of
An artificial eye, also known as a prosthetic eye or bionic eye, is
a custom-made device designed to replace a natural eye that
has been lost or removed due to injury or disease.
[1]
Advancements in technology have led to the development of
functional prosthetic eyes embedded with microelectronics and
sensors, aiming to restore partial vision to individuals with
severe visual impairments or blindness.
Microelectronics and Sensors: Capture visual from the
surrounding. Image Processing: Convert visual data into electrical signals and
enhance quality. Stimulation of Remaining Healthy Cells: Electrodes transmit
electrical signals to the retina or optic nerve. Creation of Visual Perceptions: Stimulated cells generate neural
activity interpreted as visual perceptions by the brain. Feedback Mechanisms: Adjust stimulation levels based on
environmental changes or user preferences.
A prosthetic eye, or ocular prosthesis, is an artificial eye implant that mimics the appearance of a natural human eye. Ocular prosthetics enhance the comfort and appearance of people who have lost an eye to severe injury or disease.
Common reasons why people might need a prosthetic eye include:
Eye injury
Glaucoma
Eye infection
Ocular cancer
People have been using prosthetic eyes throughout history. Long ago, prosthetic eyes were made of glass. Today, they’re made of medical-grade plastic acrylic, which is more durable.
A prosthetic eye isn’t a sphere like an eyeball. It’s a thin, removable disc that covers an ocular implant placed during eye removal surgery (enucleation). The disc is custom-made to match the existing eye.
What is an Ocularist?
An ocularist is a highly skilled professional who makes and fits ocular prostheses. They customize prosthetic eyes to resemble natural eyes. This includes an iris, pupil, sclera (white of the eye), and even blood vessels.
How Does a Prosthetic Eye Work?
After eye removal surgery, a round, porous implant gets placed in the empty socket. It may be made of coral or synthetic material. The implant gets wrapped in eye tissue and attached to muscles that enable normal eye movement.
The ocular prosthesis attaches to the implant, which is attached to the eye muscles. This allows the prosthesis to move in sync with the natural eye. You can cry, swim, and shower while wearing an ocular prosthesis.
However, an eye prosthesis won’t provide vision, and the pupil will not respond to light.
How Much Does a Prosthetic Eye Cost?
The cost of a new prosthetic eye can range from $2,000 to more than $8,000 without health i
In this day and age there is an expanding need to make artificial arms for various cruel circumstances where human communication is troublesome or incomprehensible. They may include taking readings from a dynamic spring of gushing lava to diffusing a bomb. This paper presents a study on dynamic analysis of multi degree freedom of a bionic arm that is designed in CATIA V5. The prototype is converted into standard for the exchange of product .stp file and is imported in the ANSYS software for the calculation of parameters such as maximum and minimum of deformations, stresses, strains, velocities, and acceleration. The analysis is done with giving different materials for the better optimization of the parameters such as reduced weight, less friction, and more strength. The fingers are revolute pairs that are free to rotate about certain degrees this motion is given by actuators. The arm can be improvised by using sensors, actuators and mechatronic chips so that it mimics the artificial hand. Mr. M. Sreedhar | Mrs. P. Varalakshmi | R. Naveen | S. Bharath Kumar | T. Akhil Reddy ""Dynamic Analysis of Bionic ARM"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23237.pdf
Paper URL: https://www.ijtsrd.com/engineering/mechanical-engineering/23237/dynamic-analysis-of-bionic-arm/mr-m-sreedhar
A short paper on Bionics and its implications.
For the people without disability, technology makes things easier and for the people with disability, technology makes things possible.
Low-cost and open-source anthropomorphic prosthetics hand using linear actuatorsTELKOMNIKA JOURNAL
A robust, low cost, open-source, and low power consumption in the research of prosthetics hand is essential. The purpose of this study is to develop a low-cost, open-source anthropomorphic prosthetics hand using linear actuator based on electromyography (EMG) signal control. The main advantages of this proposed method are the low-cost, lightweight and simplicity of controlling the prosthetic hand using only single channel. This is achieved by evaluating the DC motor and exploring number of locations of the EMG signal. The development of prosthetics hand consists of 3D anthropomorphic hand design, active electrodes, microcontroller, and linear actuator. The active electrodes recorded the EMG signal from extensor carpi radialis longus. The built-in EMG amplifier on the electrode amplified the EMG signal. Further, the A/D converter in the Arduino microcontroller converted the analog signal into digital. A filtering process consisted of bandpass and notch filter was performed before it used as a control signal. The linear actuator controlled each finger for flexion and extension motion. In the assessment of the design, the prosthetic hand capable of grasping ten objects. In this study, the cost and weight of the prosthetics hand are 471.99 US$ and 0.531 kg, respectively. This study has demonstrated the design of low cost and opensource of prosthetics hand with reasonable cost and lightweight. Furthermore, this development could be applied to amputee subjects.
Development of a Home-based Wrist Rehabilitation System IJECEIAES
There are several factors that may result to wrist injuries such as athlete injuries and stroke. Most of the patients are unable to undergo rehabilitation at healthcare providers due to cost and logistic constraint. To solve this problem, this project proposes a home-based wrist rehabilitation system. The goal is to create a wrist rehabilitation device that incorporates an interactive computer game so that patients can use it at home without assistance. The main structure of the device is developed using 3D printer. The device is connected to a computer, where the device provides exercises for the wrist, as the user completes a computer game which requires moving a ball to four target positions. Data from an InvenSense MPU-6050 accelerometer is used to measure wrist movements. The accelerometer values are read and used to control a mouse cursor for the computer game. The pattern of wrist movements can be recorded periodically and displayed back as sample run for analysis purposes. In this paper, the usefulness of the proposed system is demonstrated through preliminary experiment of a subject using the device to complete a wrist exercise task based on the developed computer game. The result shows the usefulness of the proposed system.
Application of Big Data Analysis and Internet of Things to the Intelligent Ac...gerogepatton
With the advent and rising usage of Internet of Things (IoT) eco-systems, there is a consequent, parallel
rise in opportunities where technology can find its place to improve a number of human conditions.
However, this is nothing new - we have been perfecting the usage of tools to aid our daily living
throughout history. The true evolution lies in the interaction between us and the tools we create. Tools
are now smart devices, yielding an opportunity where human-device interaction is giving us the very
knowledge on how to improve that particular synthesis. From improving our fitness to detecting
bradycardia and response of traumatic brain injury patient, we have come to a point where we are able
to gain actionable insight into a lot of aspects of our health and condition. This creates a certain
autonomy in understanding the unique make-up of every single person, in addition to yielding
information that can be used by health practitioners to help in diagnosis, determination of medical
approach and right recovery and follow-up methods. All of this supported by two major factors: IoT
platforms and Big Data Analysis (BDA).
This paper takes a deep dive into exemplary set-up of IoT platform and BDA framework necessary to
support the improvement of human condition. Our SmartLeg prosthetic device integrates advanced
prosthetic and robotic technology with the state-of-the-art machine learning algorithms capable of
adapting the working of the prosthesis to the optimal gait and power consumption patterns, which
provide means to customize the device to a particular user.
APPLICATION OF BIG DATA ANALYSIS AND INTERNET OF THINGS TO THE INTELLIGENT AC...ijaia
With the advent and rising usage of Internet of Things (IoT) eco-systems, there is a consequent, parallel rise in opportunities where technology can find its place to improve a number of human conditions. However, this is nothing new - we have been perfecting the usage of tools to aid our daily living throughout history. The true evolution lies in the interaction between us and the tools we create. Tools are now smart devices, yielding an opportunity where human-device interaction is giving us the very knowledge on how to improve that particular synthesis. From improving our fitness to detecting bradycardia and response of traumatic brain injury patient, we have come to a point where we are able to gain actionable insight into a lot of aspects of our health and condition. This creates a certain autonomy in understanding the unique make-up of every single person, in addition to yielding information that can be used by health practitioners to help in diagnosis, determination of medical approach and right recovery and follow-up methods. All of this supported by two major factors: IoT platforms and Big Data Analysis (BDA).
This paper takes a deep dive into exemplary set-up of IoT platform and BDA framework necessary to support the improvement of human condition. Our SmartLeg prosthetic device integrates advanced prosthetic and robotic technology with the state-of-the-art machine learning algorithms capable of adapting the working of the prosthesis to the optimal gait and power consumption patterns, which provide means to customize the device to a particular user.
APPLICATION OF BIG DATA ANALYSIS AND INTERNET OF THINGS TO THE INTELLIGENT AC...gerogepatton
With the advent and rising usage of Internet of Things (IoT) eco-systems, there is a consequent, parallel rise in opportunities where technology can find its place to improve a number of human conditions. However, this is nothing new - we have been perfecting the usage of tools to aid our daily living throughout history. The true evolution lies in the interaction between us and the tools we create. Tools are now smart devices, yielding an opportunity where human-device interaction is giving us the very knowledge on how to improve that particular synthesis. From improving our fitness to detecting bradycardia and response of traumatic brain injury patient, we have come to a point where we are able to gain actionable insight into a lot of aspects of our health and condition. This creates a certain autonomy in understanding the unique make-up of every single person, in addition to yielding information that can be used by health practitioners to help in diagnosis, determination of medical approach and right recovery and follow-up methods. All of this supported by two major factors: IoT platforms and Big Data Analysis (BDA).
Bionic Arm is the best revolution idea for amputees across the world. This is as close as we can get to our natural limb. This paper is about the study of the prosthetic arm used for amputees and gives an overview of upper limb evolution based on control technologies. It focused on the mechanical parameters like actuation system and prototyping techniques that are required to meet the design specifications. The drive systems which hold the key for proper functioning are described and their pros and cons are stated. A review of materials for prosthetic applications and role of 3D printing as a manufacturing method is discussed This would further enable to choose a system based on variables like dexterity, patients need, a weight of the system and feasibility. Detailed research of robotic limb generation could help us to develop a prosthetic limb that mimics the salient features of the limb. M. Sreedhar | S. Sai Mani Shekar | K. Aditya Vardhan | S. Vaibhav Krishna ""A Review on Bionic Arm"" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-3 , April 2019, URL: https://www.ijtsrd.com/papers/ijtsrd23221.pdf
Paper URL: https://www.ijtsrd.com/engineering/bio-mechanicaland-biomedical-engineering/23221/a-review-on-bionic-arm/m-sreedhar
A robotic arm is a Programmable mechanical arm which copies the functions of the human arm. They
are widely used in industries. Human robot-controlled interfaces mainly focus on providing rehabilitation to
amputees in order to overcome their amputation or disability leading them to live a normal life. The major
objective of this project is to develop a movable robotic arm controlled by EMG signals from the muscles of the
upper limb. In this system, our main aim is on providing a low 2-dimensional input derived from emg to move the
arm. This project involves creating a prosthesis system that allows signals recorded directly from the human body.
The arm is mainly divided into 2 parts, control part and moving part. Movable part contains the servo motor
which is connected to the Arduino Uno board, and it helps in developing a motion in accordance with the EMG
signals acquired from the body. The control part is the part that is controlled by the operation according to the
movement of the amputee. Mainly the initiation of the movement for the threshold fixed in the coding. The major
aim of the project is to provide an affordable and easily operable device that helps even the poor sections of the
amputated society to lead a happier and normal life by mimicking the functions of the human arm in terms of both
the physical, structural as well as functional aspects.
Electronics in medical sciences has been an emerging field of study and has evolved a lot. Bio electronics is a somewhat new branch that can provide more effective and convenient solutions by revolutionizing the scope of medicine forever. It involves electronic devices that can be consumed furthermore after going inside the body, capable of assisting in various procedures like a diagnosis, surgical assistance, etc. This paper focusses on delivering the fundamental concept of edible electronics, how is it helpful, its extent of application, and its challenges. Anshika Gupta "Bioelectronics - The Revolutionary Concept" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-5 , August 2020, URL: https://www.ijtsrd.com/papers/ijtsrd33022.pdf Paper Url :https://www.ijtsrd.com/biological-science/other/33022/bioelectronics--the-revolutionary-concept/anshika-gupta
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
2. Biomechatronics
An applied interdisciplinary science that integrates
mechanical elements, electronics and parts of biological
organisms
Includes aspects of biology, mechanics and electronics
Incorporates robotics and neuroscience
Aims to develop devices that interact with human
muscle, skeleton and nervous system
Simulated fingers
Biomechtronics
and
hands
are
a
branch
of
3. History
First recorded illustration of prosthetic replacement appears in the RigVeda, a religious text written in Sanskrit, compiled between 3,500 and
1,800 B.C. in India.[1]
In 1504, the Iron Hand of knight Götz von Berlichingen was constructed by
an armourer and with the help of gearwheels the fingers could be revolved
and fixed at a certain position.[2]
In 1909, D. W. Dorrance invented a split hook that was anchored to the
opposite shoulder and could be opened with a strap across the back and
closed by rubber bands.[3]
Fig: The Iron Hand of Götz von
Berlichingen
In
1915, Sauerbruch's hand was devised by a
German surgeon Ernst Ferdinand Sauerbruch in
collaboration with Aurel Stodola Slovak physicist,
turbine engineer and professor of mechanics which
was controlled and powered directly from surgically
prepared muscles of the residual limb.[4]
Fig: Sauerbruch‟s
hand
Image Sources: http://www.maximumpc.com/files/u134761/gotz.jpg
http://www.deutsches-museum.de/fileadmin/Content/TRASH/sauerbruchhand_weiss.jpg
4. Importance of
Simulated Fingers & Hands
Helps regain human motor control
that was lost or impaired by
trauma, disease or birth defects.
Minimises the
disabilities.
Allows disabled people to become
more independent.
disadvantages
of
Image Sources: http://www.wired.com/images_blogs/gadgetlab/2009/11/arms_2a.jpg
http://www.touchbionics.com/media/56932/i-limb_digits_food_prep.jpg
5. Types of
Simulated Fingers & Hands
Mind-controlled: movement of the prosthetic is driven
solely by the electrical impulses of the brain
Myoelectric: detects electrical changes in the muscles
of the stump and converts them into movements
Body-powered/Cable-controlled: controlled by cables
connecting the prosthetic limbs elsewhere on the body
Hybrid: combines two types of control in the same
prosthesis
Image Source: http://images.gizmag.com/inline/thought_controlled_permanent_prosthetic_arm-2.jpg
6. Mechanism
Simple Body-powered Prosthetic
Arm
Extending the arm or flexing the
shoulder pulls a cable attached
to a harness on the user‟s back.
As the cable tightens, it opens a
split hook at the end of the arm
and reversing the move closes
the hook.
This prosthetic arm also
provides a sensory feedbackforce which gets felt by the
Mind-controlled Prosthetic
Arm
Image and information sources: http://rehabeasy.blogspot.co.uk/2008/10/bionic-arm-mechanism.html
http://www.wired.com/wiredscience/2012/03/ff_prosthetics/all/?pid=3424&viewall=true
7.
Materials used in
Simulated Hands &
In the past iron, steel, copper and wood were the major
materials used.
Fingers
At the present, following materials used serve specific
purposes:
Titanium: lightweight, provides longer life and durability
Aluminium: lightweight and durable
Thermoplastics sockets: lightweight and give prosthesis
recipients extended comfort at the site the prosthesis is
fitted
Carbon fibre: forms lightweight pylon and gives amputees
8. Recent
iInnovations
limb
A company called „i-limb‟ has a product called the „i-digits‟ which provide
personalized electronic digits for people who have loss up to five fingers.
However, the patient must pass a selection criteria to be considered.
Each prosthetic is unique to fit the hand of the patient.
It is battery powered.
The interface material is silicone to avoid damage done to the skin and
tissue.
The „i-digit‟ is controlled using myoelectrodes or force-sensing resistors
(FSR's).[11] The electrodes can sense muscle contraction. This contraction
is filtered and processed to tell the fingers to open or close.[11]
The prosthetic can be covered with a silicon material to match the colour
and appearance of the patient's skin.
Image source: http://www.touchbionics.com/media/2197/i-limb-digits_coverings_match2.jpg
9. Recent
XInnovations
Finger
Developed by „Didrick Material‟.
Unlike the „i-digit‟ it is not electronic and does not require a power
source.[9]
Made from surgical steel and is lightweight
Are able to bend naturally with the movements from residual fingers.[9]
It is body powered meaning that the movements of the prosthetic fingers
are determined by the movements of the residual finger
This makes it user friendly and does not require any training
Each „x finger‟ is independent which allows for more articulation control,
claimed to be able to grip golf clubs and play musical instruments.[10]
A silicone cover can be applied to match the appearance of the user‟s
skin
Costs are estimated to be $1000 per digit.[10]
Image Sources: http://www.wired.com/images/article/full/2007/07/xfinger_full.jpg
http://www.asme.org/getmedia/6129d14e-06ff-4e39-84fd-031af5689cf1/everyday_prosthetic_fingers-Bioengineering-hero.jpg.aspx?width=680
10.
Aid vs. Enhancement:
Issue
“Bionic hand for 'elective amputation' patient”[5]
-Neil Bowdler, BBC News
If people with minor damages to their hands undergo amputation and replace their
hands with simulated hands for better function today, then will people with healthy
hands undergo amputation if technologically advanced simulated hands with
extraordinary features are developed in the future? Will it devalue natural hands
and life?
Cost
Transradial, below the elbow, prostheses cost between £4,000 and £5,500.[6]
Transhumeral, below the shoulder, prostheses cost between £6,500 and £10,000.[6]
Body-powered prostheses cost approximately £4,500 and Myoelectric prostheses cost approximately
£10,000.[7]
Repair costs are approximately £500 annually and the prostheses need replacing every 4 to 5 years.[8]
Image Source:
http://news.bbcimg.co.uk/media/images/52822000/jpg/_52822586_jex_10
49675_de27-1.jpg
11. References
[1]VANDERWERKER,
[2]Prosthetic
[3]Made
[4]Whonamedit?:
[5]BOWDLER,
[6]SWEENEY,
[7]BAGLEY,
[8]MARTIN,
[9]‘X
[10]‘Mechanical
[11]Touch
E.E., 2013. A Brief Review of the History of Amputations and Prostheses. ICIB 1976 Vol. 15, Num. 5, p.15-16.
Retrieved April 12, 2013, from http://www.acpoc.org/library/1976_05_015.asp
Arm through the Ages. 2013. Retrieved April 12, 2013 from http://www.medicatradefair.com/cipp/md_medica/custom/pub/content,oid,23173/lang,2/ticket,g_u_e_s_t/~/Prosthetic_Arms_through_the_Ages.html
How: Artificial Limb. 2013. Retrieved April 12, 2013, from http://www.madehow.com/Volume-1/Artificial-Limb.html
Sauerbruch’s hand. 2013. Retrieved April 12, 2013, from http://www.whonamedit.com/synd.cfm/3966.html
N., 2011. Bionic hand for „elective amputation‟ patient. BBC News Science & Environment. Retrieved April 12, 2013, from
http://www.bbc.co.uk/news/science-environment-13273348
E., 2005. Cost of prosthetics stirs debate. The Boston Globe. Retrieved April 12, 2013, from
http://www.boston.com/business/globe/articles/2005/07/05/cost_of_prosthetics_stirs_debate/
A., JAMES, M., SELF, B.P., COLEMAN R. & DENARO B., 2013. DETERMINING USAGE OF A JUVENILE MYOELECTRIC
PROSTHETIC ARM. ACPOC News 2002 Vol. 8, Num. 4, p.17-18, 20, 22, 24, 25. Retrieved April 12, 2013, from
http://www.acpoc.org/library/2002_04_017.asp
C.W., 2011. Upper Limb Prostheses. WorkSafeBC Evidence-Based Practice Group, p. 6. Retrieved April 12, 2013, from
http://www.worksafebc.com/health_care_providers/Assets/PDF/UpperLimbProstheses2011.pdf
Fingers prosthetic designed to replace lost digits’- cnet retrieved 21/04/13 at http://news.cnet.com/8301-17938_105-200716971/x-fingers-prosthetic-designed-to-replace-lost-digits/
Fingers Give Strength, Speed to Amputees’- Wired retrieved 21/04/13 at
http://www.wired.com/gadgets/miscellaneous/news/2007/07/xfinger
Bionics, retrieved 21/04/13 at http://www.touchbionics.com/products/active-prostheses/i-limb-digits/technical-information/