The document outlines the steps of a secondary survey performed on trauma patients after initial stabilization. The secondary survey is a thorough head-to-toe examination to identify all potential injuries and obtain relevant history. It involves examining the head and face, neck, chest, abdomen, genitals, extremities, skin, and performing a neurological exam. Key areas of focus include identifying signs of skull, cervical spine, rib, abdominal, urethral or rectal injuries. Sonography may also be used to identify internal injuries. The goal is to avoid missing injuries that could lead to morbidity if not identified.
Successful management of Polytrauma must achieve the following goals, 1- Keep someone alive that would be dead without you 2- Prioritize treatment to prevent killing someone 3- Treat extremity injuries to return the patient to a functional life. The Priorities are 1- Life threatening, 2- Limb threatening, 3- Function threatening. The question about the best strategy in the management Polytrauma and the choice between an Early Total Care (ETC) vs. Damage Control Orthopedics (DCO) will be answered in this presentation.
Successful management of Polytrauma must achieve the following goals, 1- Keep someone alive that would be dead without you 2- Prioritize treatment to prevent killing someone 3- Treat extremity injuries to return the patient to a functional life. The Priorities are 1- Life threatening, 2- Limb threatening, 3- Function threatening. The question about the best strategy in the management Polytrauma and the choice between an Early Total Care (ETC) vs. Damage Control Orthopedics (DCO) will be answered in this presentation.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists
Secondary Survey
1. SECONDARY
SURVEY
A D I B M U R S Y I D I I S K A N D A R M I R Z A
E T D, I I U M M E D I C A L C E N T R E
2. INTRODUCTION
• Not all injuries will be immediately apparent e.g occult injuries (delayed and missed)
• Secondary survey is a rapid but thorough head-to-toe examination assessment to identify
all potential injuries
• Performed after the primary survey, and initial stabilization is complete.
• The purpose - to obtain pertinent historical data about the patient and his or her injuries
• Indicated in all trauma patients
• Secondary survey should not be performed until:
– The primary survey has been completed
– Resuscitation has been initiated
– Normalization of vital signs has begun
3. AMPLE HISTORY
• This mnemonic device can be used for obtaining a quick, focused history:
– Allergy
– Medications
– Previous medical history or illness/pregnancy
– Last Meal
– Events/environment related to injury
• Standard precaution must be applied !
4.
5.
6. HEAD AND FACE EXAMINATION
• Examine the head for scalp hematoma, skull depression, or laceration.
• No nasogastric tube (NG) should be inserted if there is facial trauma or evidence of
basilar skull fracture.
• Ears - hemotympanum or retro-auricular ecchymosis (Battle's sign) -basilar skull
fracture with cerebrospinal (CSF) leak.
• The pupillary size and response, as well as eye movements - to look for ocular
mobility/entrapment, or periorbital ecchymosis (Raccoon eyes).
7. NECK EXAMINATION
• The neck should be carefully inspected and palpated.
• Assumed patient with blunt trauma may have sustained an injury to the cervical spine,
until proven otherwise!
• C-spine can be cleared either clinically by applying decision rules, or by obtaining
imaging studies, such as plain radiographs or a CT scan.
8. EXAMINATION OF THE CHEST
• Palpate the entire chest wall for crepitus (subcutaneous emphysema) and tenderness.
• The area over the sternum and clavicles - suggest significant force and need further
evaluation for other intrathoracic injuries.
• Assess any respiratory effort and work at breathing.
• Evaluate whether breath sounds are symmetrical and heart sounds are normal and not
muffled
• Palpate and pressure given bilateral rib cage to see any rib spring condition.
9. EXAMINATION OF THE ABDOMEN
• The abdomen should be examined for distension, bowel sounds, bruising or
tenderness.
• Presence of a seatbelt sign or other marks
• Keep in mind that the absence of abdominal tenderness does not eliminate the
possibility of abdominal injury.
• In addition, the abdominal examination may not be reliable in the following cases:
– Elderly population
– Presence of distracting injuries
– Altered mental state
– Pregnant patient, especially late pregnancy
10. EXAMINATION OF THE RECTUM AND
THE GENITALIA
• The perineum should be inspected for any evidence of injury.
• A digital rectal examination should be performed when there is a suspicion of urethral
injury or penetrating rectal injury.
• Look for the following:
– Gross blood in the rectal vault, which may indicate bowel injury
– Displaced or high-riding prostate, which may suggest urethral injury
– Abnormal sphincter tone, which may be due to a spinal cord injury.
– If blood is present at the meatus, the urethral injury should be suspected. In this situation,
retrograde urethrography should be performed before a Foley catheter is inserted.
• Consider vaginal injury in patients with lower abdominal pain, pelvic fracture or perineal
laceration
12. EXAMINATION OF THE EXTREMITIES
• The extremities should be assessed for fractures by carefully palpating each extremity
over its entire length - for tenderness and decreased the range of motion.
• Assess the integrity of uninjured joints by both active and passive movements.
– Pain/Swelling/Deformity/Crepitus
– Long bone fracture/Open fracture
– Pulses/Vascular Injuries
– Muscles – compartment
– Tendon/Joint stability
13. NEUROLOGIC EXAMINATION
• In this evaluation, the sensory and motor functions should be assessed, and the
Glasgow Coma Scale score should be repeated.
• This is important, since a patient's condition may change rapidly over time.
• The neurological assessment should also include an examination of the pupils,
including pupils' responses to light
14. SKIN EXAMINATION
• This examination should include the locations of lacerations, abrasions, ecchymosis,
hematoma, marks or bruises. Pay attention to the following areas:
– Scalp
– Axillary abdominal and gluteal folds
– Perineum
• Back should be evaluated by log-rolling the patient, and the spine should be palpated
for step-offs or focal tenderness.
15. CONCLUSION
• The primary and secondary survey is a systematic head-to-toe evaluation of trauma
patients to identify injuries – to avoid missed injuries
• This risk may be higher for the following injuries:
– Abdominal Trauma
– Blunt Trauma: Bowel injury, pancreatic and duodenal injuries, diaphragmatic rupture
– Penetrating Trauma: Rectal injuries
– Thoracic Trauma: Aortic injuries, pericardial tamponade, esophageal perforation
– Extremity Trauma: distal extremity fractures, compartment syndrome
• Missed or delayed morbidity!
An attempt should be made to obtain the patient's history regarding the mechanism of injury, since certain mechanisms can raise the suspicion for certain injuries such as the following:
Blunt trauma (seat belt use, airbag deployment, extent of damage to the automobile, ejection, and distance ejected)
Penetrating trauma (which firearm and how many gunshots heard).
What happened (example mechanisms such as blunt, penetrating, burns or any hazardous environment, such as exposure to chemicals, toxins or radiation. These considerations are important for the following reasons due to exposure to chemical agents can cause pulmonary, cardiac and other internal organ dysfunction, or hazardous environment can pose a threat to the health
The scalp should be palpated, since scalp lacerations or bony step-offs may be identified only by careful palpation.
Beware that injuries under the hard collar may not be obvious.
Uninjured joints should be immobilized, and radiographs should be obtained. Injured joints should also be immobilized, and radiographs should be obtained.
Note that to avoid the risk of any missed injuries a tertiary survey should be required in patients with multisystem trauma. So more safety precaution must be done to those patient. The more trauma of the patient, the more high risk although the more safety precaution must take place. Systemic and well planned of procedure must be done to decrease the mobility of patient.