The document discusses various diagnostic measures used to evaluate the central nervous system including lumbar puncture and CSF analysis, CT scan, MRI, EEG, myelography, evoked potentials, and more. Lumbar puncture involves inserting a needle into the spinal canal to withdraw CSF for examination. CT scans provide cross-sectional brain images while MRI uses magnetic fields to identify abnormalities. EEG records brain electrical activity and evoked potentials assess nerve conduction velocities.

1. DIAGNOSTIC MEASURES IN
NERVOUS SYSTEM

2. • The major diagnostic measures related to Central Nervous System are:-
– Lumbar puncture
– CSF analysis
– Cerebral angiography
– CT
– MRI
– Magnetic resonance angiography
– PET scan
– SPECT scan
– Cerebral ultrasound
– EEG
– EMG
– Myelography
– Evoked potential

3. LUMBAR PUNCTURE AND CSF
ANALYSIS
• Carried out by inserting a needle
into the lumbar SA space to
withdraw CSF.
• Done to obtain CSF for
examination, measure & reduce CSF
pressure, determine the presence
or absence, detect spinal SAB &
administer medications
intrathecally.
• Needle is inserted into the SA space
between 3rd & 4th or 4th & 5th
lumbar vertebrae.

4. • Specimens are obtained for cell count, culture &
glucose & protein testing.
• Specimen should be sent to lab immediately
because changes will take place & alter result if
allowed to stand.

5. • Lumbar puncture and CSF analysis.
• Result:. 70-200 mmh20- normal CSF pressure with the
pt in lateral recumbent .
• Should be clear & color less.
• Pink, blood-tinged or grossly bloody CSF may indicate
a cerebral contusion, laceration or hemorrhage.

6. COMPLICATIONS:
• Herniation of intracranial contentsb.
• Spinal epidural abscess/hematoma.
• Meningitis.
• Temporary voiding problems.
• Slight increase of temperature.
• Backache or spasms.
• Stiffness of neck.
• Post lumbar puncture headache

7. POST LUMBAR PUNCTURE
HEADACHE
• Caused by CSF leakage at the puncture site. The fluid
continues to escape into the tissues by way of the
needle track, from the spinal canal. It is then absorbed
promptly by the lymphatics.
• As a result, the supply of CSF in the cranium is
depleted at point at which it is insufficient to maintain
proper mechanical stabilization of the brain.

8. • This leakage of CSF allows settling of the brain
when the patient assumes an upright position,
producing tension & stretching the venous sinuses
and pain-sensitive structures.
• Both traction and pain are lessened & the leakage
is reduced when the pt lies down.

9. NURSING INTERVENTIONS
• Signed consent and void before the procedure. Use
small gauged needles.
• Instruct to relax to avoid traumatic or bloody tap, fetal
position. A local anesthetic will be used.
• Patient remains on prone position 2 – 3 hours post
procedure
• Headache is managed by rest, analgesics & hydration

10. CT SCAN
• It is a non-invasive and painless
procedure & has a high degree
of sensitivity for detecting
lesions.- makes use of a narrow
x-ray beam to scan the head in
successive layers. The images
provide cross sectional views of
the brain or other organs.-
performed first without
contrast then with IV contrast
enhancement.-

11. NURSING INTERVENTIONS
• patient lies in adjustable table with the head in
fixed position while the scan system rotates
around the head & produces cross-sectional
images.
• The patient must stay still because motion will
distort the image

12. • Teaching the patient about the need to lie quietly and still
throughout the procedure.
• Sedation can be used if agitation, restlessness or confusion
will interfere with a successful study.
• Instruct patient to be on nothing per oral for at least 4
hours.
• Monitoring pt for allergic reaction of contrast agent and
other side effects
• Increase hydration to flush out contrast

13. • It is useful in showing metabolic changes in
the brain (Alzheimer’s), locating lesion
(tumor, epileptogenic lesion), identifying
blood flow and O2 metabolism in patients
with strokes, evaluating new therapies for
brain tumors and revealing biochemical
abnormalities associated with mental
illness.

14. ELECTROENCEPHALOGRAPHY
• Represents a record of the
electrical activity generated
in the brain. Obtained
through electrodes applied in
the scalp or through
electrodes applied within the
brain tissue.
• Provides a physiologic
assessment of cerebral
activity.

15. • Electrical activity of brain is recorded using scalp
electrodes. Evaluates seizure disorders, cerebral disease,
CNS effects of systemic diseases, brain injury, brain death.
Specific tests may be done to evaluate brains electrical
response to lights and loud noises
• Nurses Responsibility
– Before: Tell patient procedure is noninvasive and without danger of
electric shock.
– Determine if any medications (e-8, tranquilizers, anti – seizure
drugs) should be withheld.
– After: Resume medications and have patient wash electrode paste
out of hair.

16. • Useful test for diagnosing and evaluating seizure
disorders, coma, or organic brain syndromes.
Tumors brain abscesses, blood clots, and infection
may cause abnormal patterns in electrical activity.

17. NURSING INTERVENTIONS
• Patient is deprived of sleep.
• Anti-seizures, tranquilizers, stimulants, depressants are
withheld 24-48 hours (can alter/mask abnormal wave patterns
of seizure disorders.
• No coffee, tea, chocolate & cola (all stimulants)
• Meal should NOT be omitted - altered blood glucose change
brain wave.
• Patient is informed that it would take 45-60 minutes for awake
& 12 hours for sleep EEG.

19. MYELOGRAPHY
• An x-ray of the spinal subarachnoid space taken
after the injection of contrast agent into the spinal
subarachnoid space through a lumbar puncture.
• Shows any distortion of the spinal cord or spinal
dural sac caused by tumors, cysts, herniated
vertebral disks or other lesions

20. NURSING INTERVENTIONS
• Information of the procedure; meal prior to
procedure is omitted;
• Sedative may be given
• After procedure, patient may lie in bed with HOB
at 30-45 degrees for 3 hours.

21. Electromyography
• Electromyography (EMG) is the recording of electrical activity
associated with innervation of skeletal muscle. Needle
electrodes are inserted into the muscle to record specific motor
units. Normal muscle at rest shows no electrical activity.
Electrical activity occurs only when the muscle contracts.
• Activity may be altered in diseases of muscle (eg, myopathic
conditions) or in disorders of muscle innervation (eg, segmental
or LMN lesions, peripheral neuropathic conditions).
• Nurses Responsibility
– Before: Explain procedure. Tell patient that pain and discomfort are
associated with insertion of needles. HCPs may caffeine) restrict
simulants (e.g. caffeine) 2-3 hrs prior.
– After Assess needle sites for hematoma or inflammation. Give as-
needed analgesics.

22. MAGNETIC RESONANCE IMAGING
• Helps identify cerebral abnormality more early
and clearly than other test by using a highly
magnetic field.
• The test may be done with or without a contrast.
• The magnet causes hydrogen ions in the body
(protons) to align like small magnets and emit
signals which are converted into images.

23. NURSING REPONSIBILITIES
• Remove all metal objects from the patient and inside the
examination room.
• Instruct patient that it is painless but he may hear loud
thumping
• Inform that he or she may communicate to the staff via a
microphone inside the scanner.
• For claustrophobic patients, sedation may be used.
• Ask about history of pacemaker or cochlear implants.

25. CEREBRAL ANGIOGRAPHY
• X – ray study of cerebral
circulation after injection of a
dye to a selected artery (usually
femoral artery) under local
anesthesia and heparinized
saline.
• Valuable for detection of
aneurysm, AV malformations
and other vascular diseases.
• Series of X-rays are taken.

26. NURSING RESPONSIBILITIES
• Ensure well hydration and clear
liquids before the test.
• Instruct to void before the test.
• Location of peripheral pulses are
marked with a felt – tip pen.
• Shave the area (groin).
• Instruct to remain immobile during
the test, brief feeling of warmth
behind the eyes, face, jaw, teeth,
tongue and lips and a metallic taste
after dye injection..
• After the test, monitor for signs
and symptoms of occlusion,
apply cold compress to relive
hematoma.
• Closely observe for bleeding.
• Instruct the patient to expect a
warm feeling over the face and
metallic taste when the dye is
injected.

27. CEREBRAL ULTRASOUND
• Ultrasound imaging of the head
uses sound waves to produce
pictures of the brain and
cerebrospinal fluid. It is most
commonly performed on infants,
whose skulls have not completely
formed.
• A transcranial Doppler ultrasound
evaluates blood flow in the brain's
major arteries. Ultrasound is safe,
noninvasive, and does not use
ionizing radiation.

28. Positron Emission Tomography (PET)
• Computerized nuclear imaging technique that
produces images of actual organ functioning.
Patient either inhales radioactive gas or injected,
that emits positively charged particles
• It produces a 3-D image of functional processes in
the body by detecting the radiation emitted by
photons .

29. • The system detects pairs of gamma rays emitted indirectly by
positron emitting radionuclide (tracer), which was previously
injected in body on a biologically active molecule.
• 3-D images of tracer concentration within the body are then
constructed by computer analysis
• Modification of PET is called SPECT.
– SPECT uses less precise but more stable and
commercially available isotopes to measure cerebral
blood flow.

30. NURSING INTERVENTIONS
• Patient preparation
• Explanation of the test
• Teaching patient of inhalation techniques
• Sensation

31. EVOKED POTENTIAL
• Evoked potentials (EPs) are a
useful diagnostic test to help
identify abnormalities of the
peripheral and central nervous
system that may help explain
why the patient is having pain
or functional disability.
• It used to assess the trasmit
time of afferent pathway of the
cerebral hemisphere and the
brain stem.
• Stimulus used are .
• Visual, entering the body
through the eyes
• Auditory, entering through the
ears
• Somatosensory stimulation or
touch, when sensations enter
via the skin

32. • Evoked potentials :- electrical activity associated
with nerve conduction along sensory pathways is
recorded by electrodes placed on skin and scalp. A
Stimulus generates the impulse. Increases in the
normal time from stimulus onset to a given peak
(latency) indicate slowed nerve conduction or nerve
damage. Used to diagnose disease (e.g, MS), locate
nerve damage, and monitor function during surgery.
Can diagnose disorders of the visual or auditory
systems because it shows if a sensory impulse is
reaching the right part of brain.
• Nurses Responsibility
– Before: Explain procedure to patient. Have patient
shampoo hair before test.

33. Elecroneurograpy
• Elecroneurograpy conduction (nerve studies) Measures
nerve conduction velocity of peripheral nerves. involves
applying a brief electrical stimulus to a distal portion of
a sensory nerve and recording the resulting wave of
depolarization at a point proximal to the stimulation.
The time between the stimulus onset and the first wave
of depolarization at the recording electrode is measured.
Damaged nerves have slower conduction velocities.
• Nurses Responsibility
– Before: Explain procedure to patient For example, a stimulus
can be applied to the forefinger and a recording electrode
placed over the median nerve at the wrist will detect the
speed of the conduction.

34. Magnetoencephalography
• Magnetoencephalography :- Uses a
biomagnetometer to detect magnetic fields
generated by neural activity, Can accurately
pinpoint the part of the brain involved in a
stroke, seizure or other disorder or injury.
Measures , extracranial magnetic fields and
scalp electric field (EEG).
• Nurses Responsibility
– Before: Explain procedure to patient. MEG, a
passive sensor, does not make a physical contact
with patient.