Rib fractures are commonly caused by blunt chest trauma and are often seen following motor vehicle crashes and falls. While usually not life-threatening on their own, they can indicate more severe underlying injuries to the chest or abdomen. Treatment focuses on pain management to prevent respiratory complications and complications are more common in elderly patients and those with multiple rib fractures.
Presentation of common upper limb fractures and dislocations. Covering all the injuries from many sides (Definition - Classification - Mechanisms of injury - Clinical features - Radiological studies - Management - Complications)
This is short presentation of most common fracture in hip joint. Femoral neck fractures are the most common type of fractures around the hip joint- more common in elderly in weak osteoporotic bone. This presentation gives a brief idea about these fractures, investigations, methods of management in different age groups.
Seminar presentation by 4th year medical student of Lincoln University College, supervised by HRPZ Orthopedic's specialist.
Reference were from reliable medical websites and also from texttbook; Apley and Solomon's Concise System of Orthopaedics and Trauma, 4th Ed.
The presentation is for the use of Physiotherapy students. It covers a brief introduction, classification, clinical features and general principles of management.
Presentation of common upper limb fractures and dislocations. Covering all the injuries from many sides (Definition - Classification - Mechanisms of injury - Clinical features - Radiological studies - Management - Complications)
This is short presentation of most common fracture in hip joint. Femoral neck fractures are the most common type of fractures around the hip joint- more common in elderly in weak osteoporotic bone. This presentation gives a brief idea about these fractures, investigations, methods of management in different age groups.
Seminar presentation by 4th year medical student of Lincoln University College, supervised by HRPZ Orthopedic's specialist.
Reference were from reliable medical websites and also from texttbook; Apley and Solomon's Concise System of Orthopaedics and Trauma, 4th Ed.
The presentation is for the use of Physiotherapy students. It covers a brief introduction, classification, clinical features and general principles of management.
PowerPoint presentation on Intercostal drainage (ICD) or Chest tube drainage. In this this presentation I have included different methods by which a chest tube can be inserted to drain fluid, pus, air from the Pleural cavity. please do mail me your feedback on this presentation at tinkujoseph2010@gmail.com.
Acute management and decision making in spinal cord injury by dr ss sharmadrshyamsundersharma
These slides made by references of spinal cord medicine books for information,education and communication of physicians,paramedics and peoples by which early appropriate, accessible measures can be taken for mandatory spine cord injury care and management.
BIRTH INJURIES IN NEWBORN: Definition of birth injuries , statistics, etiology, classification of birth injuries , head injuries: cephalhematoma and Caput succedaneum, skull fractures
, nerve injuries: erb's palsy and klumpke's palsy, bone injuries: clavicular and long bone fracture , intra-abdominal and soft tissue injuries, management and prevention of birth injuries
Cervical spine trauma and spinal cord injuries by Dr Shamavu Gabriel.pptxGabriel Shamavu
PAEDIATRICS TRAUMA ADVANCED LIFE SUPPORT PRESENTATION
Cervical spine trauma and spinal cord injuries
Prepared by Dr GABRIEL KAKURU SHAMAVU, Resident in Paediatrics and child health at Kampala International University Teaching Hospital. With Mentorship of Professor Yamile Arias Ortiz. Tutor of the course of "Paediatrics Emergencies and life support". Mars 2022
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
2. Background
• Simple rib #s are the most common injury
sustained following blunt chest trauma.
• Approximately 10% of all patients admitted after
blunt chest trauma have one or more rib #s.
• These #s are rarely life-threatening in themselves
but can be an external marker of more severe
visceral injury inside the abdomen and the chest.
3. • The most common mechanism of injury for rib #s
in elderly persons is a fall from height or from
standing.
• In adults, MVA is the most common mechanism.
• Youths sustain rib #s most often secondary to
recreational and athletic activities, as well as by
non-accidental trauma.
4. • Rib #s may also be pathologic. Cancers that
metastasize to bone (eg, prostate, breast,
renal) frequently become apparent in a rib.
• Ribs are relatively thin compared with major
long bones and are more likely to # when
invaded by a metastatic lesion.
5. • The chest wall protects underlying sensitive
structures by surrounding internal organs with
hard osseous structures including the ribs,
clavicles, sternum, and scapulae.
• An intact chest wall is necessary for normal
respiration.
6. • Rib #s may compromise ventilation by a variety of
mechanisms. Pain from rib #s can cause respiratory
splinting, resulting in atelectasis and pneumonia.
• Multiple contiguous rib #s (i.e., flail chest) interfere
with normal costovertebral and diaphragmatic
muscle excursion, potentially causing ventilatory
insufficiency.
7. • Fragments of #ed ribs can also act as
penetrating objects leading to the formation
of a hemothorax or a pneumothorax.
• Ribs commonly # at the point of impact or at
the posterior angle (structurally their weakest
area). Ribs four through nine (4-9) are the
most commonly injured.
8. • The thinnest and weakest portion of the first
rib is at the groove for the subclavian artery.
• The mechanism of first-rib injury in MVAs
seems to be a violent contraction of the
scalene muscles brought on by the sudden
forward movement of the head and neck.
9. • A single blow may cause rib #s in multiple
places.
• Traumatic #s most often occur at the site of
impact or the posterolateral bend, where the
rib is weakest.
• Due to the greater pliability of children's ribs,
greater force is required to produce a #.
10. Mortality/Morbidity
• Rib #s are not usually
dangerous in and of
themselves.
• Patients may develop
pneumonia from
splinting.
• Morbidity correlates
with the degree of
injury to underlying
structures.
11. Age
• Because children have more elastic ribs, they
are less likely than adults to sustain #s
following blunt chest trauma.
• Elderly individuals are more likely to have
associated injuries and complications.
12. Clinical Presentation
• Description of the prehospital scene by
paramedics can provide important clues to the
possibility of rib #s.
• After MVA, deformation of the steering wheel
and activation of seat belts and airbags have
been associated with rib injuries.
• Patients with rib # frequently complain of pain
on inspiration and dyspnea.
13. • Rib #s have been reported after coughing
spells without other significant trauma.
• Athletes with high force, recurrent
movements of the arms (e.g., discus throwers)
have had stress #s of the upper and middle
ribs.
14. • Tenderness on palpation, crepitus, and chest
wall deformity are common findings of rib #.
• Paradoxical chest wall excursion with
inspiration is seen with flail chest.
15. • A flail chest occurs when a large segment of ribs
is not attached to the spine.
• These ribs are broken in at least 2 places on each
rib.
• The paradoxical movement occurs because the
middle section of the rib between the 2 # sites
moves in response to intrathoracic pressure
changes not intercostal muscle contractions.
16. • Specific signs of ventilatory insufficiency
include cyanosis, tachypnea, retractions, and
use of accessory muscles for ventilation.
• Less specific signs include anxiety and
agitation.
17. • Bruising near # site is uncommon in pediatric
rib #s.
• If # of the lower ribs is suspected, assess the
patient for abdominal tenderness and costal
margin tenderness, which could raise
suspicion for injury to intra-abdominal organs.
18. Causes
• Blunt trauma including
motor vehicle crashes,
assault, falls, especially
down staircases.
• Coughing spells
• Non-accidental trauma in
pediatric cases
• Repetitive minor trauma
• Stress #s to the first rib in
throwing athletes
19. Chest radiographs
• AP and lateral chest films are used routinely to
assist in the diagnosis of rib #s.
• Chest radiographs are much more useful in the
diagnosis of underlying injuries, including
hemothorax, pneumothorax, lung contusion,
atelectasis, pneumonia, and vascular injuries.
• Findings of sternal # or scapular # should
increase suspicion for rib #s.
21. Emergency care
• Goal of initial ED care is stabilization of the
trauma patient and multisystem trauma
evaluation.
• Respiratory care, including use of incentive
spirometry to prevent atelectasis and its
complications, is often important.
• Holding a pillow or similar soft brace against the
# site reduces discomfort while using the
spirometer or when coughing.
22. • Pain control is fundamental to the management
of rib #s to decrease chest wall splinting and
alveolar collapse in order to clear pulmonary
secretions.
• Isolated rib #s, without associated injuries, may
be managed on an outpatient basis with oral
analgesics, starting with NSAIDs if not
contraindicated and progressing to narcotics if
not sufficient.
23. • While rib belts or binders
do control pain, they have
been linked to
hypoventilation,
atelectasis, and
pneumonia.
• As a result, their use is no
longer recommended.
24. • For patients with a
significant mechanism of
trauma, a CT of the chest
and abdomen can be
useful in scanning for
significant related injury.
• It is recommended that
hospital admission for any
patient with 3 or more rib
#s, and ICU care for
elderly patients with 6 or
more rib #s.
25. Further Outpatient Care
• Patients with minor rib injuries able to cough and
clear secretions may be discharged with
adequate analgesic medications.
• Adequate analgesics are critical to successful
outpatient management of rib #s.
• Most patients who will develop complications will
do so within 2 weeks, so a follow-up plan within 2
weeks should be made.
26. • Consider an incentive spirometer, especially
with multiple #s, as it may help avoid
complications and remind the patient to avoid
splinting and to take deep breaths.
27. Further Inpatient Care
• Patients with isolated rib #s who are unable to cough
and clear secretions adequately should be considered
for admission for 24-hour observation.
• Consider admission for patients with underlying lung
disease or decreased pulmonary reserve.
• A lower threshold for admission of older persons with
isolated rib #s is warranted because of their higher
incidence of hypoventilation, hypercapnia, atelectasis,
and pneumonia.
28. Prognosis
• Isolated rib #s in
younger patients have a
good prognosis.
• Older patients have a
higher incidence of
significant pulmonary
complications.
29. Patient Education
• Return to work or sport depends on the activity
involved and the level of pain.
• Heavy labor and intensive training for athletes with
stress #s are not recommended for the first 3 weeks.
• When pain is not present at rest, the patient can begin
to increase his or her activity level but this should be
gradually done.
• Most rib #s heal within 6 weeks.
30. • Virtually all nonpathologic rib #s heal well
with conservative management.
• Some patients are able to return to work
within a few days, depending on their
occupation.
32. Fracture of the sternum
• Fracture of the sternum can be caused either by direct
trauma, which requires extreme force and is usually
associated with other injuries, or by violent flexion of the
thoracic spine accompanied by a wedge fracture of the
thoracic spine.
• Fractures of the sternum are not serious in themselves and
usually unite soundly, but their presence should alert the
doctor to the possibility of a more serious injury. A flail
segment including the mediastinum may be difficult to
control, even by positive pressure respiration (see Fig. 11.3).
33. • Treatment
If the fractured sternum is not properly
aligned it may need reduction and wiring.