This document discusses rectal and perianal bleeding. It begins by outlining the objectives, history, examination, tests, and differential diagnosis. For history, it describes key questions about the color, amount and relationship to stools of the bleeding. Examination includes a PR exam and checking for signs of systemic illness or lymph node involvement. Tests include bloodwork, stool samples, imaging like CT/MRI, and endoscopy with biopsy. The differential diagnosis section lists possible causes depending on where the blood is seen, such as hemorrhoids, IBD, diverticulitis, or anal tear.