1. RBC ABNORMALITY
Ms Ankita R Bhatiya
Assistant Professor
Shree P.M.Patel COLLEGE OF PARAMEDICAL
SCIENCE N TECHNOLOGY
2. RBC ABNORMALITY
Abnormalities in RBC Their Clinical Significance :
1.Normal red blood cells
a)Round cells & They have a small area of central
pollar
b)Only slight variation in size
6. RBC ABNORMALITY
5. Spherocytes(Hyperchromia):
a) Cells are not biconcave
b) No central area of pallor part
c) Smaller surface area for the cell size.
d) Inherited disorder or in autoimmune haemolytic
anaemia
7. RBC ABNORMALITY
6. Target Cells
a) These cells have a centrally stained area
b) Thalassaemia, iron deficiency
14. RBC ABNORMALITY
13. Acanthocytes
a) Red cells with sharp, irregular, thorn like projections
on the outer edge
b) Associated with abnormal phospholipids metabolism
15. RBC ABNORMALITY
14. Burr cells
a) Red blood cells with pointed projections on their
outer edge
b) Occur as an artefact or uraemia & some other
conditions
16. RBC ABNORMALITY
15. Basophilic stippling
a) Presence of fine or coarse purple staining granules
in the red cells
b) Thalassaemia, lead poisoning, infections & blood
disorder
17. RBC ABNORMALITY
16. Siderocytes (pappenheimer bodies)
a) Purple coloured granules of iron in led cell
b) Haemolytic anaemia after Splenectomy
18. RBC ABNORMALITY
17.Howell-Jolly body
a) Round purple staining nuclear fragments in the red
blood cell h) Seen in Post-splenectomy patients &
also appear in haemolytic & megaloblastic
anaemia
19. RBC ABNORMALITY
18. Cabot ring
a) Purple staining, thread like filaments in the shape of
a ring in red cell
b) Haemolytic & megaloblastic anaemia
22. RBC ABNORMALITY
21. Creneted cells
a) Red cells having irregular outer edges.
b) This is often due to faulty drying of blood smears
23. RBC ABNORMALITY
22. Heinz bodies
It is found in patients with glucose-6-phosphate
deficiency and the patient is prone to drug induced
anaemia or chemical poisoning