Newer Modes of 
Mechanical Ventilation 
Timothy A. Morris, M.D. 
Division of Pulmonary and Critical Care Medicine 
Medical Director, Respiratory Care 
University of California, San Diego
How to Assess Ventilator Modes 
 Inhalation 
» what is controlled during the breath 
» what is targeted (how much is enough?) 
» how does it adjust to changes
How to Assess Ventilator Modes 
 Exhalation 
» what is controlled 
» when does it end 
» how does it adjust
How to Assess Ventilator Modes 
 Inhalation 
» what is controlled 
» what is targeted 
» how does it adjust
Simple Pressure System 
Pressure 20 cm H2O 
Pressure 
20 cm H2O
Time Constant 
 time it takes to get 1/2 way to 
equilibrium 
 total resistance x total compliance
Increased Compliance 
Pressure 20 cm H2O 
Pressure 
20 cm H2O
Increased Resistance 
Pressure 20 cm H2O 
Obstruction 
Pressure 
20 cm H2O
Simple Volume System 
Volume 500 ml 
Pressure 3500 cm H20 
Volume 500 ml
Simple Volume System 
Volume 2000 ml 
Pressure 3500 cm H20 
Pop!
Big Secret! 
 Ventilator modes are simulations 
» pressure control 
» volume control 
 Microprocessors control the simulation
Dadmobile
Minivan Tire
High Pressure Pump
Filling the Tire
Tire Pressure
Toy Balloon: deflated
Toy Balloon: inflated
Toy Balloon: popped
Flow Control
Control of Resistor
High Pressure System 
Pressure 3500 cm H20 
Pressure 35 cm H20 
Tidal volume 500 ml
Volume Control 
Deflated Volume Inflated Volume
Pressure Control 
Deflated Pressure Inflated Pressure
What controls the adjustments? 
Volume? 
(flow control) 
Pressure?
Microprocessor Control 
solenoid 
Pressure 3500 cm H20 
Microprocessor 
Tidal volume 500 ml 
Pressure 35 cm H20
Quality of the control 
 hardware: 
» how frequently is the flow/pressure 
measured 
» how rapidly are adjustments made 
» how are adjustments made 
 software 
» timing and patterns of control
How to Assess Ventilator Modes 
 Inhalation 
» what is controlled 
» what is targeted 
» how does it adjust
Targeting 
 How much breath is enough?
Targeting 
Control 
 Flow 
 Pressure 
Target 
 Time 
 Pressure 
 Volume 
Volume 
control
Targeting 
Control 
 Flow 
 Pressure 
Target 
 Time 
 Pressure 
 Volume 
Time-cycled 
pressure 
control
Targeting 
Control 
 Flow 
 Pressure 
Target 
 Time 
 Pressure 
 Volume 
Volume 
targeted 
pressure 
control
How to Assess Ventilator Modes 
 Inhalation 
» what is controlled 
» what is targeted 
» how does it adjust
Patients generate pressures 
 Negative pressure 
» inhalation efforts 
 Positive pressure 
» “bucking”
Negative pressure: Adjustments 
 No adjustment 
 Increase in pressure/flow to match 
demand 
 Decrease in pressure/flow to foster 
weaning
Positive pressure: Adjustments 
 No adjustment 
 End inhalation, open exhalatory 
valve 
 Adjust inspiratory and expiratory 
valves to maintain control
How to Assess Ventilator Modes 
 Exhalation 
» next year
Coming up next... 
Reality

Power point -_modes_of_ventilation