An excellent tool to treat refractory hypoxia. Target audience are ICU junior physicians and Respiratory Therapists. It will take away the fear of "What is APRV?" from your hearts and you will feel ready to give it a try.
Basic information on the Graphics displayed on the Ventilators. Prepared to educate about the graphics to train the professionals who work with Ventilators.
An excellent tool to treat refractory hypoxia. Target audience are ICU junior physicians and Respiratory Therapists. It will take away the fear of "What is APRV?" from your hearts and you will feel ready to give it a try.
Basic information on the Graphics displayed on the Ventilators. Prepared to educate about the graphics to train the professionals who work with Ventilators.
Non-invasive ventilation (NIV) is the use of breathing support administered through a face mask or nasal mask. Learn more about NIV in this presentation by Dr Somnath Longani, consultant Anaesthesiologist & Intensivist, Midland Healthcare & Research Center, lucknow
https://midlandhealthcare.org/
this is compiled & created to discuss the basic modes and initiation of NIV
the author is thankful to the previous authors,teachers who helped to conceptualize the NIV .
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
15. Pressure then raises to assure that the set tidal volume is delivered New Volume Targeted Breath Pressure Variability is Controlled
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Editor's Notes
16 Some of these settings, such as FiO 2 , respiratory rate, tidal volume, inspiratory time or I:E ratio, and mode of ventilation, are specified primarily by the physician. Sensitivity, or how easily the patient can trigger the ventilator into the inspiratory phase, and peak flow are usually not physician ordered. The goal with the FiO 2 is to keep it below 50% if possible. Tidal volume is usually at 6-12 ml/kg, depending on the ventilation management strategy. In volume-based ventilation, delivery of the set tidal volume is what terminates inspiration. Peak flow determines how fast the tidal volume is delivered. In pressure-based ventilation, reaching the set inspiratory pressure and inspiratory time is what normally terminates inspiration. Let’s look more closely at the modes of ventilation.
45 How do you know the problem is with the patient? Look at your flow curve.
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35 Let’s begin with a definition of PEEP or positive end expiratory pressure. PEEP is the application of a clinician-set, positive pressure applied at end exhalation. This prevents pressure from returning to zero, or atmospheric, at the end of the breath. When positive pressure is applied at the end of a mechanical breath, it is referred to as PEEP. When positive pressure is applied throughout the spontaneous breathing cycle, it is referred to as CPAP, or continuous positive airway pressure. Let’s look at a graphic representation of PEEP.
36 On this pressure-time graph, we know that the first breath is mechanically initiated since there is no negative deflection preceding that breath. Note the breath does not begin at the zero base line, but instead begins at 5 cm H 2 O pressure. The mechanical breath is delivered, but at end exhalation, pressure remains at 5 cm H 2 O. The next breath is spontaneous (note the inspiratory deflection). Here again, pressure throughout the breath cycle is elevated by 5 cm H 2 O. The final breath is a patient-initiated, mechanical breath, again showing that at end exhalation, pressure is maintained at 5 cm H 2 O. Why do we add PEEP? Once again, we’ll try to mimic this effect. Take a normal breath in, but do not exhale all the way, thus maintaining some positive pressure in your lungs. What could be the benefit of positive pressure at the end of exhalation? PEEP causes an increase in functional residual capacity or FRC. The FRC is the amount of air left in your lungs at the end of a normal exhalation. This increased volume can improve oxygenation; more air remains available to participate in gas exchange. In sick lungs, PEEP can also help recruit or open collapsed alveoli. Keep in mind that with many lung pathologies, alveoli have the tendency to collapse. PEEP can be applied at pressures sufficient to overcome this tendency to collapse, keeping the alveoli patent and functional. Finally, in cases of excess pulmonary fluid, PEEP can cause this unwanted lung fluid to move from the alveoli into the perivascular space.
37 Now that you understand the physiologic effects of PEEP, you can apply the same knowledge to CPAP. The only difference is that CPAP is the application of positive pressure throughout the spontaneous ventilatory cycle. Since this is a totally spontaneous mode, the patient must have an intact respiratory center.
38 This graphic depicts the CPAP mode set at 10 cm H 2 O. Similar to Pressure Support, the patient determines the respiratory rate and tidal volume. Keep in mind that CPAP and PSV are often used in conjunction. CPAP can prevent or minimize alveolar collapse, while Pressure Support helps overcome resistance and augments tidal volume. CPAP, either alone or in combination with Pressure Support, is often the final form of support prior to extubation.
21 8 Synchronized breaths may improve patient comfort and reduce competition between the patient and ventilator. Because the patient is in full control of the spontaneous breaths, patient ventilator synchrony is enhanced. Hyperventilation is less of a concern compared to A/C. Let’s take a look at some concerns with SIMV.
23 The delivered volume is constant in volume ventilation; in pressure ventilation, volume varies with changes in resistance and compliance. In volume ventilation, inspiratory pressure varies with changes in compliance and resistance; with pressure ventilation, the inspiratory pressure is set and remains constant. Inspiratory flow is constant in volume ventilation but varies in pressure ventilation. In volume ventilation, inspiratory time is determined by the set flow and tidal volume; in pressure ventilation the inspiratory time is set by the clinician. Let’s move on to our discussion of Pressure Control Ventilation.
27 17 One advantage of Pressure Control Ventilation is a decreased risk of barotrauma caused by overdistention. Also, longer inspiratory time may recruit collapsed and flooded alveoli, improving gas distribution. One disadvantage is that tidal volumes vary when patient compliance changes, such as with ARDS or pulmonary edema. Setting a low tidal volume alarm or minute volume alarm alerts the clinician to this changing status so the patient can be re-evaluated. Another issue with increased inspiratory time is the potential need for heavy sedation or chemical paralysis. Newer ventilators incorporate an active exhalation valve. An active exhalation valve can open during the setinspiratory time in Pressure Contraol Ventilation, allowing the patient to breathe spontaneously during the inspiratory phase. It remains to be seen whether a decrease in the use of paralytics will result with the active exhalation valve.
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