Pk2

Clinical Pharmacokinetics and Pharmacodynamics Janice E. Sullivan, M.D. Brian Yarberry, Pharm.D.

Why Study Pharmacokinetics (PK) and Pharmacodynamics (PD)? ,[object Object],[object Object],[object Object],[object Object]

Clinical Pharmacokinetics ,[object Object]

Absorption ,[object Object],[object Object],[object Object],[object Object],[object Object]

Absorption in the Pediatric Patient ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Distribution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pediatric Distribution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Metabolism ,[object Object],[object Object],[object Object]

Metabolism ,[object Object],[object Object],[object Object],[object Object],[object Object]

Phase I reactions ,[object Object],[object Object],[object Object],[object Object],[object Object]

Phase I reactions types ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Phase II reactions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Elimination ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pediatric Elimination ,[object Object],[object Object],[object Object]

Pharmacokinetic Principles ,[object Object],[object Object]

Steady State Pharmacokinetics ,[object Object],[object Object]

Loading Doses ,[object Object],[object Object]

Linear Pharmacokinetics ,[object Object],[object Object]

Nonlinear Pharmacokinetics ,[object Object],[object Object]

Michaelis-Menten Kinetics ,[object Object],[object Object]

Special Patient Populations ,[object Object],[object Object],[object Object]

Pharmacogenetics ,[object Object],[object Object]

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