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![Haim R. Branisteanu
12 Gotlieb Street Tel Aviv 03-523-2744 e-mail haimbranisteanu@gmail.com
Vitamin K and D and their interactions January 19 2016 Page 2 of 8
To implement the above, problems will arise, and I anticipate the main issue, would be
transfer of funds from the Ministry of Health to the Ministry of Agriculture in an orderly and
strictly supervised fashion to improve substantially of the public health.
Vitamin K may improve bone health, according to a 2001 research review published in
Nutrition. Sizing up the available data on vitamin K and bone health, the review's authors
found that vitamin K can increase bone mineral density and reduce fracture rates in people
with osteoporosis. The authors note that vitamin K may be particularly effective when
combined with vitamin D, a nutrient known to play a critical role in bone metabolism.
Preliminary findings from animal-based studies indicate that vitamin K may protect against
atherosclerosis (hardening of the arteries). However, in a 2008 report from Current
Opinion in Lipidology, scientists caution that human-based research on vitamin
K1 and heart disease has yielded mixed results.
Chickens’ legs are the generators of D in chickens and synthesis by modified duckweed that
emphasis absorption of vitamin K between other in chicken manure lagoon or cow manure
lagoon and added to the animal diets or administered with my other BWW (threated bark
and woody waste) product can be a winning solution. (I discussed this in my proposed
project at the time but with cow manure)
2. Vitamin K2 Protects your heart; lowers cardiovascular disease and mortality
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946231/
Vitamin K2 helps to prevent hardening of the arteries, which is a common factor in coronary
artery disease and heart failure. Research suggests vitamin K2 may help to keep calcium out
of your artery linings and other body tissues, where it can cause damage. The latest studies
show it is vitamin K2, rather than K1, in concert with vitamin D, that prevents calcification in
your coronary arteries, thereby preventing cardiovascular disease.
3. Vitamin K2 Helps Prevent Osteoporosis
The absolute best way to achieve healthy bones is a diet rich in fresh, raw whole foods that
maximizes natural minerals so your body has the raw materials it needs to do what it was
designed to do. Vitamin K2 is one of the most important nutritional interventions for
improving your bone density. It serves as the biological "glue" that helps plug calcium and
other important minerals into your bone matrix. There have been some remarkable research
studies about the protective effects of vitamin K2 against osteoporosis [1]
https://www.ncbi.nlm.nih.gov/pubmed/23525894 :
A number of Japanese trials have shown that vitamin K2 completely reverses bone loss and,
in some cases, even increases bone mass in people with osteoporosis. The pooled evidence of
seven Japanese trials shows, that vitamin K2 supplementation produces a 60% reduction in
vertebral fractures and an 80 percent reduction in hip and other non-vertebral fractures.
Researchers in the Netherlands showed vitamin K2 is three times more effective than vitamin
K1 in raising osteocalcin, which controls the building of bone in vertebrates.
1
Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy
postmenopausal women.](https://image.slidesharecdn.com/vitaminkworksinconjunctionwithd002-260209192940-a6ce542c/85/Vitamin-K-works-in-conjunction-with-D-to-the-Knesset-pdf-2-320.jpg)
![Haim R. Branisteanu
12 Gotlieb Street Tel Aviv 03-523-2744 e-mail haimbranisteanu@gmail.com
Vitamin K and D and their interactions January 19 2016 Page 3 of 8
Your bone strength depends on more than just calcium. Your bones are actually composed of
more than a dozen minerals. If you focus just on calcium, you will likely weaken your bones
and increase your risk of osteoporosis, as Dr. Robert Thompson explains in his book “The
Calcium Lie”. It's more likely your body can use calcium correctly if it's plant-derived
calcium. Good sources include raw milk from pasture-raised cows (who eat the calcium-rich
plants), leafy green vegetables, the pith of citrus fruits, carob, and wheatgrass, to name a few.
4. Vitamin K Helps Prevent Cancer
A number of studies have shown that vitamins K1 and K2 are effective against cancer.
Consider the following:
One study published in September 2003 in the International Journal of Oncology, found that
treating lung cancer patients with vitamin K2 slowed the growth of cancer cells, and previous
studies have shown benefit in treating leukemia. In an August 2003 study published in the
Alternative Medicine Review2 involving 30 patients with a type of liver cancer called
hepatocellular carcinoma, who took oral vitamin K1, the disease stabilized in six patients;
seven patients had a partial response; and seven others had improved liver function. In 15
patients, abnormal prothrombin normalized.
In 2008, a German research group discovered vitamin K2 provides substantial protection
against prostate cancer, one of the most common types of cancer among men in the United
States. According to Dr. Vermeer, [2] men taking the highest amounts of K2 had
about 50 percent less prostate cancer.
Vitamin K has also been found beneficial in the fight against non-Hodgkin lymphoma, colon,
stomach, nasopharynx, and oral cancers.
5. Additional Health Benefits of Vitamin K
As written in the March 2004 Life Extension magazine 4, researchers have found many other
beneficial effects of vitamin K including:
2
OSLO, NORWAY -- Renowned vitamin K2 researcher, Dr. Cees Vermeer, Professor of the Cardiovascular
Research Institute Maastricht, University of Maastricht, the long-time research partner of Natto-Pharma ASA,
Oslo, Norway, has been identified as being among the top 2.5% of all scientists worldwide by the independent
monitoring agency Research Gate. Recently, Dr. Vermeer has led a research team that studied vitamin K2
menaquinone-7 for three years and that has shown the most significant bone health finding in recent history:
vitamin K2, taken daily for the long-term such as a multivitamin, can prevent bone loss/porosity in women --
even after menopause.
Professor Vermeer belongs to the world’s top-2½ % of scientists, received an Honorary Doctorate (in 2001) at
the Iuliu Hatieganu University of Medicine and Pharmacy in Cluj Napoca, Romania, is a Visiting Professor at
the American University and has been a temporary advisor of the World Health Organization.
Professor Vermeer’s current research activities include molecular biology, biochemistry, animal and human
nutrition, pharmacology, and clinical trials in arteriosclerosis and osteoporosis. He has held a wide variety of
administrative positions within the Maastricht University, including Chairman of the Department of
Biochemistry and Member of Medical Faculty Board (portfolio R&D). Professor Vermeer has supervised 17
PhD students, is author of over 350 international scientific publications and inventor of 14 patents and patent
applications.](https://image.slidesharecdn.com/vitaminkworksinconjunctionwithd002-260209192940-a6ce542c/85/Vitamin-K-works-in-conjunction-with-D-to-the-Knesset-pdf-3-320.jpg)
![Haim R. Branisteanu
12 Gotlieb Street Tel Aviv 03-523-2744 e-mail haimbranisteanu@gmail.com
Vitamin K and D and their interactions January 19 2016 Page 6 of 8
through a lipid-lowering effect. The review also showed the influence Vit. K has on age-
related neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease.
Vit. K is involved in the brain’s physiology and can reduce its cognitive decline by
carboxylation of Growth arrest-specific protein 6, a Vit. K-dependent protein that could
defend against neuronal apoptosis induced by OS[3] and amyloid beta. The anticancer
potential of Vit. K was summarized by reviewing several in vitro and epidemiological studies.
There are multiple mechanisms where the potential anticancer agent of Vit. K can react,
including the modulation of various transcription factors, which induced antiproliferative,
proapoptotic, and autophagic effects, which were found to be associated with a reduced risk
of cancer. The latest evidence on Vit. K and pulmonary disease stem from the fact that Vit. K
can activate protein S, which was recently shown to prevent the generation of inflammatory
cytokines and cytokine storms detected in COVID-19 cases. Low levels of protein S, due to
pneumonia-induced Vit. K depletion, were correlated with higher thrombogenicity and
possibly fatal outcomes in COVID-19 patients. Proteins S acts as a principal cofactor to
protein C, the two proteins in the blood help regulate blood clot formation, inactivating
specific coagulation factors V & VIII when needed Protein S formation is triggered with Vit. K
Consuming a healthy diet is vital throughout the aging process to maintain and promote
wellbeing. The aging population may be at risk for many suboptimal nutrient intakes,
including Vit. K, which have been shown to be associated with adverse health outcomes
highly prevalent in this age group. Thus, the intake of Vit. K-rich diets or Vit. K supplements
could prevent age-related diseases and/or support the effectiveness of medical treatments.
However, more studies are needed to formulate the exactly recommended intakes of Vit. K,
including Vit. K1, Menaquinone-4, and Menaquinone-7, due to their distinct bioavailability
and biological activities. According to this review, higher values of Vit. K intakes are needed,
especially among the elderly and people who have co-morbidities conditions that are most
likely to be Vit. K deficient.
Addendum 1: Nutritional Value of the Duckweed Species of the Genus Wolffia
(Lemnaceae) as Human Food, & also as a feeding additive to chickens, pigs, and milking cows
within their feed. https://www.frontiersin.org/articles/10.3389/fchem.2018.00483/full
Crop yield of 25t/hectare dry duckweed were achieved under controlled conditions.
Species of the genus Wolffia are traditionally used as human food in some of the Asian
countries. Therefore, all 11 species of this genus, identified by molecular barcoding, were
investigated for ingredients relevant to human nutrition. The total protein content varied
between 20 and 30% of the freeze-dry weight, the starch content between 10 and 20%, the
fat content between 1 and 5%, and the fiber content was ~25%. The essential amino acid
content was higher or close to the requirements of preschool-aged children according to
standards of the World Health Organization. The fat content was low, but the fraction of
polyunsaturated fatty acids was above 60% of total fat and the content of n-3
polyunsaturated fatty acids were higher than that of n-6 polyunsaturated fatty acids in
most species. The content of macro- and microelements (minerals) not only depended on the
cultivation conditions but also on the genetic background of the species. This holds true also
for the content of tocopherols, several carotenoids and phytosterols in different species and
3
The length of time from either the date of diagnosis or the start of treatment for a disease, that patients is diagnosed
with the disease are still alive. In a clinical trial, measuring the OS is one way to see how well a new treatment works.](https://image.slidesharecdn.com/vitaminkworksinconjunctionwithd002-260209192940-a6ce542c/85/Vitamin-K-works-in-conjunction-with-D-to-the-Knesset-pdf-6-320.jpg)
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