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Basic Physics for
Anaesthetists
2/15/2019 1WUBIE B
Outline
 Objectives
 Introduction
 The physics of flow
 The gas laws
2/15/2019 2WUBIE B
Objectives
• After completion of this course students will be able to
describe:-
– Basic concept on physics of fluid
– Basic concepts on gas laws and its implications
2/15/2019 3WUBIE B
INTRODUCTION
 For the safe & efficient use of anaesthetic apparatus, the
anaesthetist must have a clear concept of the physical aspects of
the equipment in use.
 Understanding of basic concepts may avert unnecessary
accidents & near misses.
 Measurable terms and the physical laws apply to all states of
matter (i.e. solids, liquids and gases).
2/15/2019 4WUBIE B
I. The Physics of Flow
2/15/2019 5WUBIE B
 Flow is defined as the quantity of liquid(gas, vapour or
sublimate) that passes a point per unit time
 A simple equation to represent this is:
• Flow is sometimes written as ∆Q (rate of change of a
quantity)
• Due to the number of different fluids that are given to
our patients during a routine anesthetic, flow is
obviously an important area of physics to understand.
2/15/2019 WUBIE B 6
Biophysics flow
 Flow is determined by 2 factors
1. Pressure difference (P) -
 Flow(Q) from high pressure to low pressure.
 Q depends on P1-P2 (P) (pressure gradient)
2. Resistance (R)
R= measure of friction between
 tube/blood vessel and moving fluid
 Fluid molecules within themselves
72/15/2019 WUBIE B
 As fluid flows through tubes there is resistance, between
the fluid and vessel wall that opposes the flow.
 For any given system, this resistance is constant and can be
expressed as:
 Q = P (Ohm’a law)
R
R Depends on type of fluid and dimension of tube and on:
 Viscosity of fluid ( ) – directly proportional
 Tube length (L)- directly proportional
 Tube radius (r) - indirectly proportional (R as radius
)
2/15/2019 8WUBIE B
92/15/2019 WUBIE B
Hagen– Poiseuille equation
 where p is pressure drop along the
tube (p1 − p2).
 r is radius of tube
 l is length of tube and
 η is viscosity of fluid.
2/15/2019 10WUBIE B
• Determinants of laminar flow
A. Pressure across tube
B. Diameter of tube
C. length of tube
D. Viscosity of tube
2/15/2019 11WUBIE B
A. Gradient pressure (ΔP)
 For flow to occur, there must be a pressure difference (ΔP)
between the ends of a tube.
 ΔQ is directly proportional to ΔP.
• The greater the pressure difference, the greater the flow.
2/15/2019 12WUBIE B
B. Tube diameter /Radius
• flow is proportional to the 4th power of the radius.
• If the diameter of the tube is halved the flow through it reduces
to one sixteenth.
• If the radius doubles, the flow through the tube will increase by
16 times
2/15/2019 13WUBIE B
2/15/2019 14WUBIE B
C. Length
 Flow is inversely proportional to the length of the tube.
 If the length is doubled the flow is halved
 A central line is much longer than a cannula, and for the same
diameter fluid flows more slowly.
2/15/2019 15WUBIE B
D. Viscosity
 Viscosity of fluid also affects the flow of fluid
 viscosity increase in following condition
- Polycythemia , Increased fibrinogen level
- Hypothermia , cigarette smoking
- Age
 Increased viscosity leads to increase risk of vascular
occlusion .
2/15/2019 16WUBIE B
 Anaesthetic implication
• During fluid resuscitation, a short wide bore cannula
e.g.14G is superior to a 20G cannula or a central line.
• Intubating patients with very small tube increases
resistance to flow and thus pressure increases to deliver
the same amount of flow through the tube.
2/15/2019 17WUBIE B
 The physics of flow
o Flow can be divided into Three different types
1. Laminar flow
2. Transitional flow
3. Turbulent flow
o A number of different physical characteristics determine
whether a fluid obeys the principles of one or the other.
2/15/2019 18WUBIE B
1.Laminar flow
• Normal and noiseless.
 All elements of the fluid move in a stream line, that are parallel
to the axis of the tube.
 No fluid move in radial or circumferential direction.
 Layer of fluid in contact with the wall is motionless (thin layer,
adherent to wall, hence motionless)
 Fluid that move along the axis of the tube has maximum Velocity.
192/15/2019 WUBIE B
• Laminar flow
• Reynold’s number < 2000
• 'low' velocity
• Fluid particles move in
straight lines.
2/15/2019 20WUBIE B
fig. Diagrammatic representation of laminar flow
• If the mean velocity of the
flow is v, then the molecules
at the centre of the tube are
moving at approximately 2v
(twice the mean),
• the molecules at the side of
the tube are almost
stationary.
2/15/2019 21WUBIE B
2. Turbulent blood flow
 Various elements of fluid move irregularly in axial,
radial and circumferential direction.
• More pressure required to drive blood than laminar
• Energy wasted in propelling blood radially and axially
• Often accompanied by noise(murmurs).
• Occur at valves and aorta (normal), at site of blood
clot(pathological).
222/15/2019 WUBIE B
2/15/2019 23WUBIE B
2/15/2019 24WUBIE B
Turbulent Flow
• The fluid particles do not move in orderly manner and
they occupy different relative positions in successive
cross-sections.
• The flow is unpredictable
• High velocity
• Average motion is in the direction of the flow
• Changes / fluctuations are very difficult to detect.
• Most common type of flow.
• Particle paths completely irregular
2/15/2019 25WUBIE B
• Laminar flow change to turbulent flow if constriction is
reached
– Velocity of fluid increases
– Fluid is no longer in a smooth fashion
– Resistance is higher than for the same laminar flow .
– Flow is no longer directly proportional to pressure
2/15/2019 26WUBIE B
Occurrence of turbulent flow depends on:
• Velocity of blood flow (v)- directly proportional
 Diameter of the tube (d) – directly proportional
 Density of the tube (p)-directly proportional
 Viscosity of the fluid ()- indirectly proportional.
Turbulence in normal circulation:
 Heart chambers -- - - -v & d large
 Big arteries near heart ----v & d large
272/15/2019 WUBIE B
 Reynold’s number (Re).
• There is a number that can be calculated in order to
identify whether fluid flow is likely to be laminar or
turbulent and this is called Reynold’s number (Re).
2/15/2019 28WUBIE B
Re : Reynold’s number,
ρ: Density of fluid
v: Velocity of fluid
d: Diameter of tube and
η : viscosity of fluid.
• Reynold’s number is dimensionless (it
has no units).
• Re < 2000 flow is likely to be
laminar
• Re > 2000 flow is likely to be
turbulent.
• Reynold’s number of 2000 delineates
laminar from turbulent flow.
2/15/2019 29WUBIE B
302/15/2019 WUBIE B
3. Transitional flow
• Transitional flow
• Reynolds's number-2000-4000
• 'medium' velocity
2/15/2019 31WUBIE B
Clinical Aspects Of Flow
• Laminar flow is present in bronchioles, smaller air passage as they are
narrower than trachea.
• Turbulent flow is present in corrugated rubber tubing .
• Sharp bend or angles increase turbulence
• In quiet breathing , the flow in resp tract is laminar, while speaking ,
coughing or taking deep breath turbulent flow tends to occur .
• A lining layer of mucus may affect the flow .
• In circulatory system, bruit and murmur can be heard due to
turbulence of flow.
2/15/2019 32WUBIE B
Bernoulli’s Principle
• Describes the relationship between the velocity and pressure
exerted by a moving liquid.
• Applied to both liquids as well as gases.
• Venturi effect is based on the Bernoulli’s principle.
• Venturi effect is entrainment of fluid (gas or liquid ) due to the
drop in pressure
2/15/2019 33WUBIE B
Applications of Venturi effect
• Venturi masks used for oxygen therapy.
• Sander’s jet injector.
• Nebulisation chambers.
• Atomizers that disperse perfumes or spray paints.
• Water aspirators.
• Foam fire fighting nozzles and extinguishers.
• Modern vaporizers.
• Sand blasters to mix air and sand.
• Vehicle carburetors.
2/15/2019 34WUBIE B
Fig. Venturi effect
venturi face mask
venturi face mask
2/15/2019 35WUBIE B
 Coanda effect
 is the tendency of the fluid jet to be attached to a nearby
surface.
 When a narrow tube encounters a Y junction of the wide bore,
because the flow tends to cling to one side, the flow will not
evenly divide between the two outlets, but flows through only one
limb of the Y piece. This behavior is called Coanda Effect.
2/15/2019 36WUBIE B
 Coanda Effect
 If a constriction occurs at bifurcation because of increase in
velocity and reduction in the pressure, fluid (air, blood) tends to
stick to one side of the branch causing maldistribution.
2/15/2019 37WUBIE B
Coanda Effect
Application:
1. Mucus plug at the branching of tracheo-bronchial tree may
cause maldistribution of respiratory gases.
2. Unequal flow may result because of atherosclerotic plaques in
the vascular tree
3. Fluid logic used in ventilators employs this principle to
replace valves or mobile parts.
2/15/2019 38WUBIE B
2/15/2019 39WUBIE B
II. The Gas Laws
2/15/2019 40WUBIE B
 Introduction
• As anesthetists we deal with liquids & gases under pressure at
varying temperatures and volumes.
• These inter-relationships are simple, measurable and their
understanding ensures a safe outcome for the patient.
2/15/2019 41WUBIE B
• Definitions
• What is a gas?
 Gas : is a substance that is in its gaseous phase, but is above its
critical temperature.
 Vapour: a substance in the gaseous phase but is below its critical
temperature.
 Critical temperature : the temperature above which a gas cannot be
liquefied no matter how high the pressure.
2/15/2019 42WUBIE B
• What is pressure?
• Defined as "the force per unit area acting at
right angles to the surface under consideration”
• Pressure = Force/Area
• The unit of pressure is the Pascal.
 Units ,1 Barr = 1 Atm = 100Kpa
=760mmHg=760torr = 14.7Psi = 1000cmH20 .
2/15/2019 43WUBIE B
 What is temperature?
 Measures heat, a form of energy, kinetic energy which comes
from movement of the molecules.
 Temperature is measured in the Celsius or Fahrenheit scales.
 In Physics it is the Kelvin.
 The divisions of the Kelvin and Celsius scale are the same but
the start points differ.
 0oC is 273K, so body temperature is 310K on this scale.
2/15/2019 44WUBIE B
Basic Concepts of Gas Laws
 The relationship between the three variables,
1. Volume
2. Pressure
3. Temperature is explained by the gas laws
2/15/2019 45WUBIE B
Definitions of the gas laws
1. Boyle’s Law
o At constant temperature (T) , the volume(V) of a fixed amount of
a gas is inversely proportional to its pressure(P).
o V α 1 / p
o PV = Constant ( if T is kept constant).
2/15/2019 46WUBIE B
2. Charle’s Law
• At constant pressure, volume of a gas is directly proportional to
the temperature. V α T or V / T = K (constant)
• APPLICATION:
• Respiratory gas measurements of tidal volume & vital capacity
etc are done at ambient temperature while these exchanges
actually take place in the body at 37 OC.
2/15/2019 47WUBIE B
3. Gay Lussac’s law/ the third gas Law
• At constant volume pressure is directly proportional to the
temperature. P α T or P/T = K (constant)
 Application
• Medical gases are stored in cylinders having a constant volume and
high pressures (138 Barr in a full oxygen / air cylinder).
• If these are stored at high temperatures, pressures will rise causing
explosions
2/15/2019 48WUBIE B
The gas laws
2/15/2019 49WUBIE B
 Perfect gas
• A gas that completely obeys all three gas laws.
• Or A gas that contains molecules of infinitely small size,
which, therefore, occupy no volume themselves, and
which have no force of attraction between them.
• No such gas actually exists still.
2/15/2019 50WUBIE B
The end!!!
2/15/2019 WUBIE B 51

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Physics and anesthesia (0) (0)

  • 2. Outline  Objectives  Introduction  The physics of flow  The gas laws 2/15/2019 2WUBIE B
  • 3. Objectives • After completion of this course students will be able to describe:- – Basic concept on physics of fluid – Basic concepts on gas laws and its implications 2/15/2019 3WUBIE B
  • 4. INTRODUCTION  For the safe & efficient use of anaesthetic apparatus, the anaesthetist must have a clear concept of the physical aspects of the equipment in use.  Understanding of basic concepts may avert unnecessary accidents & near misses.  Measurable terms and the physical laws apply to all states of matter (i.e. solids, liquids and gases). 2/15/2019 4WUBIE B
  • 5. I. The Physics of Flow 2/15/2019 5WUBIE B
  • 6.  Flow is defined as the quantity of liquid(gas, vapour or sublimate) that passes a point per unit time  A simple equation to represent this is: • Flow is sometimes written as ∆Q (rate of change of a quantity) • Due to the number of different fluids that are given to our patients during a routine anesthetic, flow is obviously an important area of physics to understand. 2/15/2019 WUBIE B 6
  • 7. Biophysics flow  Flow is determined by 2 factors 1. Pressure difference (P) -  Flow(Q) from high pressure to low pressure.  Q depends on P1-P2 (P) (pressure gradient) 2. Resistance (R) R= measure of friction between  tube/blood vessel and moving fluid  Fluid molecules within themselves 72/15/2019 WUBIE B
  • 8.  As fluid flows through tubes there is resistance, between the fluid and vessel wall that opposes the flow.  For any given system, this resistance is constant and can be expressed as:  Q = P (Ohm’a law) R R Depends on type of fluid and dimension of tube and on:  Viscosity of fluid ( ) – directly proportional  Tube length (L)- directly proportional  Tube radius (r) - indirectly proportional (R as radius ) 2/15/2019 8WUBIE B
  • 10. Hagen– Poiseuille equation  where p is pressure drop along the tube (p1 − p2).  r is radius of tube  l is length of tube and  η is viscosity of fluid. 2/15/2019 10WUBIE B
  • 11. • Determinants of laminar flow A. Pressure across tube B. Diameter of tube C. length of tube D. Viscosity of tube 2/15/2019 11WUBIE B
  • 12. A. Gradient pressure (ΔP)  For flow to occur, there must be a pressure difference (ΔP) between the ends of a tube.  ΔQ is directly proportional to ΔP. • The greater the pressure difference, the greater the flow. 2/15/2019 12WUBIE B
  • 13. B. Tube diameter /Radius • flow is proportional to the 4th power of the radius. • If the diameter of the tube is halved the flow through it reduces to one sixteenth. • If the radius doubles, the flow through the tube will increase by 16 times 2/15/2019 13WUBIE B
  • 15. C. Length  Flow is inversely proportional to the length of the tube.  If the length is doubled the flow is halved  A central line is much longer than a cannula, and for the same diameter fluid flows more slowly. 2/15/2019 15WUBIE B
  • 16. D. Viscosity  Viscosity of fluid also affects the flow of fluid  viscosity increase in following condition - Polycythemia , Increased fibrinogen level - Hypothermia , cigarette smoking - Age  Increased viscosity leads to increase risk of vascular occlusion . 2/15/2019 16WUBIE B
  • 17.  Anaesthetic implication • During fluid resuscitation, a short wide bore cannula e.g.14G is superior to a 20G cannula or a central line. • Intubating patients with very small tube increases resistance to flow and thus pressure increases to deliver the same amount of flow through the tube. 2/15/2019 17WUBIE B
  • 18.  The physics of flow o Flow can be divided into Three different types 1. Laminar flow 2. Transitional flow 3. Turbulent flow o A number of different physical characteristics determine whether a fluid obeys the principles of one or the other. 2/15/2019 18WUBIE B
  • 19. 1.Laminar flow • Normal and noiseless.  All elements of the fluid move in a stream line, that are parallel to the axis of the tube.  No fluid move in radial or circumferential direction.  Layer of fluid in contact with the wall is motionless (thin layer, adherent to wall, hence motionless)  Fluid that move along the axis of the tube has maximum Velocity. 192/15/2019 WUBIE B
  • 20. • Laminar flow • Reynold’s number < 2000 • 'low' velocity • Fluid particles move in straight lines. 2/15/2019 20WUBIE B
  • 21. fig. Diagrammatic representation of laminar flow • If the mean velocity of the flow is v, then the molecules at the centre of the tube are moving at approximately 2v (twice the mean), • the molecules at the side of the tube are almost stationary. 2/15/2019 21WUBIE B
  • 22. 2. Turbulent blood flow  Various elements of fluid move irregularly in axial, radial and circumferential direction. • More pressure required to drive blood than laminar • Energy wasted in propelling blood radially and axially • Often accompanied by noise(murmurs). • Occur at valves and aorta (normal), at site of blood clot(pathological). 222/15/2019 WUBIE B
  • 25. Turbulent Flow • The fluid particles do not move in orderly manner and they occupy different relative positions in successive cross-sections. • The flow is unpredictable • High velocity • Average motion is in the direction of the flow • Changes / fluctuations are very difficult to detect. • Most common type of flow. • Particle paths completely irregular 2/15/2019 25WUBIE B
  • 26. • Laminar flow change to turbulent flow if constriction is reached – Velocity of fluid increases – Fluid is no longer in a smooth fashion – Resistance is higher than for the same laminar flow . – Flow is no longer directly proportional to pressure 2/15/2019 26WUBIE B
  • 27. Occurrence of turbulent flow depends on: • Velocity of blood flow (v)- directly proportional  Diameter of the tube (d) – directly proportional  Density of the tube (p)-directly proportional  Viscosity of the fluid ()- indirectly proportional. Turbulence in normal circulation:  Heart chambers -- - - -v & d large  Big arteries near heart ----v & d large 272/15/2019 WUBIE B
  • 28.  Reynold’s number (Re). • There is a number that can be calculated in order to identify whether fluid flow is likely to be laminar or turbulent and this is called Reynold’s number (Re). 2/15/2019 28WUBIE B
  • 29. Re : Reynold’s number, ρ: Density of fluid v: Velocity of fluid d: Diameter of tube and η : viscosity of fluid. • Reynold’s number is dimensionless (it has no units). • Re < 2000 flow is likely to be laminar • Re > 2000 flow is likely to be turbulent. • Reynold’s number of 2000 delineates laminar from turbulent flow. 2/15/2019 29WUBIE B
  • 31. 3. Transitional flow • Transitional flow • Reynolds's number-2000-4000 • 'medium' velocity 2/15/2019 31WUBIE B
  • 32. Clinical Aspects Of Flow • Laminar flow is present in bronchioles, smaller air passage as they are narrower than trachea. • Turbulent flow is present in corrugated rubber tubing . • Sharp bend or angles increase turbulence • In quiet breathing , the flow in resp tract is laminar, while speaking , coughing or taking deep breath turbulent flow tends to occur . • A lining layer of mucus may affect the flow . • In circulatory system, bruit and murmur can be heard due to turbulence of flow. 2/15/2019 32WUBIE B
  • 33. Bernoulli’s Principle • Describes the relationship between the velocity and pressure exerted by a moving liquid. • Applied to both liquids as well as gases. • Venturi effect is based on the Bernoulli’s principle. • Venturi effect is entrainment of fluid (gas or liquid ) due to the drop in pressure 2/15/2019 33WUBIE B
  • 34. Applications of Venturi effect • Venturi masks used for oxygen therapy. • Sander’s jet injector. • Nebulisation chambers. • Atomizers that disperse perfumes or spray paints. • Water aspirators. • Foam fire fighting nozzles and extinguishers. • Modern vaporizers. • Sand blasters to mix air and sand. • Vehicle carburetors. 2/15/2019 34WUBIE B
  • 35. Fig. Venturi effect venturi face mask venturi face mask 2/15/2019 35WUBIE B
  • 36.  Coanda effect  is the tendency of the fluid jet to be attached to a nearby surface.  When a narrow tube encounters a Y junction of the wide bore, because the flow tends to cling to one side, the flow will not evenly divide between the two outlets, but flows through only one limb of the Y piece. This behavior is called Coanda Effect. 2/15/2019 36WUBIE B
  • 37.  Coanda Effect  If a constriction occurs at bifurcation because of increase in velocity and reduction in the pressure, fluid (air, blood) tends to stick to one side of the branch causing maldistribution. 2/15/2019 37WUBIE B
  • 38. Coanda Effect Application: 1. Mucus plug at the branching of tracheo-bronchial tree may cause maldistribution of respiratory gases. 2. Unequal flow may result because of atherosclerotic plaques in the vascular tree 3. Fluid logic used in ventilators employs this principle to replace valves or mobile parts. 2/15/2019 38WUBIE B
  • 40. II. The Gas Laws 2/15/2019 40WUBIE B
  • 41.  Introduction • As anesthetists we deal with liquids & gases under pressure at varying temperatures and volumes. • These inter-relationships are simple, measurable and their understanding ensures a safe outcome for the patient. 2/15/2019 41WUBIE B
  • 42. • Definitions • What is a gas?  Gas : is a substance that is in its gaseous phase, but is above its critical temperature.  Vapour: a substance in the gaseous phase but is below its critical temperature.  Critical temperature : the temperature above which a gas cannot be liquefied no matter how high the pressure. 2/15/2019 42WUBIE B
  • 43. • What is pressure? • Defined as "the force per unit area acting at right angles to the surface under consideration” • Pressure = Force/Area • The unit of pressure is the Pascal.  Units ,1 Barr = 1 Atm = 100Kpa =760mmHg=760torr = 14.7Psi = 1000cmH20 . 2/15/2019 43WUBIE B
  • 44.  What is temperature?  Measures heat, a form of energy, kinetic energy which comes from movement of the molecules.  Temperature is measured in the Celsius or Fahrenheit scales.  In Physics it is the Kelvin.  The divisions of the Kelvin and Celsius scale are the same but the start points differ.  0oC is 273K, so body temperature is 310K on this scale. 2/15/2019 44WUBIE B
  • 45. Basic Concepts of Gas Laws  The relationship between the three variables, 1. Volume 2. Pressure 3. Temperature is explained by the gas laws 2/15/2019 45WUBIE B
  • 46. Definitions of the gas laws 1. Boyle’s Law o At constant temperature (T) , the volume(V) of a fixed amount of a gas is inversely proportional to its pressure(P). o V α 1 / p o PV = Constant ( if T is kept constant). 2/15/2019 46WUBIE B
  • 47. 2. Charle’s Law • At constant pressure, volume of a gas is directly proportional to the temperature. V α T or V / T = K (constant) • APPLICATION: • Respiratory gas measurements of tidal volume & vital capacity etc are done at ambient temperature while these exchanges actually take place in the body at 37 OC. 2/15/2019 47WUBIE B
  • 48. 3. Gay Lussac’s law/ the third gas Law • At constant volume pressure is directly proportional to the temperature. P α T or P/T = K (constant)  Application • Medical gases are stored in cylinders having a constant volume and high pressures (138 Barr in a full oxygen / air cylinder). • If these are stored at high temperatures, pressures will rise causing explosions 2/15/2019 48WUBIE B
  • 50.  Perfect gas • A gas that completely obeys all three gas laws. • Or A gas that contains molecules of infinitely small size, which, therefore, occupy no volume themselves, and which have no force of attraction between them. • No such gas actually exists still. 2/15/2019 50WUBIE B

Editor's Notes

  1. Physics is the world in measurable terms and the physical laws apply to all states of matter (i.e. solids, liquids and gases).
  2. This is the mass of a substance (in this case a fluid), that passes a certain point in one second.” The units are Litres per second
  3. Resistance = ΔP / ΔQ , R (constant) (This can be compared with V=IR in electrical physics).
  4. The Hagen-Poiseuille equation defines the flow through a tube and how this flow is affected by the attributes of the tube; the length and radius, and the attributes of the fluid; the viscosity
  5. (We squeeze a bag of IV fluid, to increase the pressure difference between the bag and the vein, so that the fluid is given quicker!).
  6. This means that flow is directly proportional to D4 (Think about how much more rapidly fluid flows through a 22G and 16G cannula).
  7. A fluid flows in a steady manner No eddies or turbulence Present in smooth tubes Velocity is low Flow is greatest at centre ( 2x mean flow) To draw the fluid , a pressure difference must be present across the ends of tube.
  8. This is therefore the type of flow we would expect to see when a fluid floes through a cannula or a tracheal tube.
  9. Transitional flow: the flow occurs between laminar and turbulent flow .
  10. An increase in the flow velocity of an ideal fluid will be accompanied by a simultaneous reduction in its pressure. Describes the relationship between the velocity and pressure exerted by a moving liquid. Applied to both liquids as well as gases.
  11. Anaesthesiologist will be dealing with many of the gases which are needed for anaesthetizing patients every day
  12. Pressure is the consequence of molecular bombardment of the surface by the gas. Kinetic energy is transferred to the surface and a force is produced that creates the pressure. If the volume falls, the pressure goes up because the area for collisions fall and so more kinetic energy transfer per unit area, and so an increase in pressure.
  13. STP = Standard Temperature and Pressure T = O OC P = 760mmHg Absolute Temp. O OK = -273 OC
  14. ● Gas exists in the gaseous state at room temperature and pressure. Vapour is the gaseous state of a substance below its critical temperature. At room temperature and atmospheric pressure, the substance is liquid.
  15. It is important to realize that this is a theoretical concept and no such gas actually exists. Hydrogen comes the closest to being a perfect gas as it has the lowest molecular weight. In practice, most commonly used anaesthetic gases obey the gas laws reasonably well.