Periphlebitis Retinae, also known as Eale's Disease, is an idiopathic inflammatory condition of the peripheral retinal veins that presents with recurrent vitreous and retinal hemorrhages in young adult males, typically between ages 20-30. It is caused by inflammation of the retinal vein walls that is commonly associated with tuberculosis. Symptoms include sudden vision impairment due to vitreous hemorrhage. Signs include thickened, tortuous, and congested peripheral retinal veins and large vitreous hemorrhages. Treatment focuses on treating any underlying infections like tuberculosis, photocoagulation of leaking retinal areas, and vitrectomy for advanced cases with retinitis proliferans.

1. Periphlebitis Retinae
[Eale’s Disease]
By - Raju Rathore
B.opto 3 Sam
ITM UNIVERSITY RAIPUR

2. INTRODUCTION
• idiopathic
• inflammatory peripheral retinal
vasculopathy which presents
withrecurrent vitreous and retinal
haemorrhages in young males

3. Etiology
• There is periphlebitis, i.e.inflammation of
the wall of the retinal veins commonly
associated with tuberculosis
(tuberculoprotein hypersensitivity)

5. Incidence
• Age—Young adults (20-30 years) are affected
commonly
• Sex—It occurs in males usually. It is a bilateral
condition
Symptom
• Usually none but there may be sudden impairment of
vision due to vitreous haemorrhage

6. Signs
• A large vitreous haemorrhage may occur all of a
sudden
• Peripheral retinal veins appear thickened,
tortuousand congested
Complications
• Loss of vision
• Retinitis proliferans
• Rubeosis iridis, glaucoma and cataract may
develop in late stages

7. Treatment
• Photocoagulation of leaking areas prevents retinal
hypoxia
• Treat the underlying cause of inflammation, e.g.
tuberculosis or septic foci
• Vitrectomy with division of fibrous bands is
recommended in cases of retinitis proliferans

8. Reference
Basic ophthalmology /4rth edition /Renu Jogi/page
305/306

9. Thank You
Raju Rathore
B.opto 3sem