Parkinson's disease is a disorder of the central nervous system that causes a loss of motor control. It occurs when nerve cells in the basal ganglia region of the brain that produce dopamine die or become impaired. This leads to a lack of dopamine in the brain, causing symptoms like shaking, rigidity, slow movement, and difficulty walking. While the exact causes are unknown, it may be related to genetic or environmental factors. In advanced stages, thinking problems and dementia become more common.