This document discusses Parkinson's disease, including its definition, signs and symptoms, causes, pathophysiology, diagnosis, treatment, and nursing management. Parkinson's is a progressive nervous system disorder that causes movement issues like tremors and rigidity. It results from the loss of dopamine-producing neurons in the brain. While the exact cause is unknown, risk factors include age, genetics, and environmental toxins. Treatment focuses on increasing dopamine levels through medications or surgery. Nurses help manage symptoms, monitor for complications, and promote independence and safety.
Parkinson's Disease, SYMPTOMS OF PARKINSONISM, STAGES OF PARKINSONISM, ETIOLOGY OF PARKINSONISM, PATHOPHYSIOLOGY OF PARKINSONISM, TREATMENT OF PARKINSONISM.
During my 1st &2nd year of residency period , i used to teach Anatomy and Orthopaedics for foreign undergraduate medical students. At last year i taught Neurology for one batch. so i posted some of my collections for competely educational purpose coz i believe in knowledge ...inseted of deleting these ppts , they may me useful for others so i shared it ....
Parkinson's Disease, SYMPTOMS OF PARKINSONISM, STAGES OF PARKINSONISM, ETIOLOGY OF PARKINSONISM, PATHOPHYSIOLOGY OF PARKINSONISM, TREATMENT OF PARKINSONISM.
During my 1st &2nd year of residency period , i used to teach Anatomy and Orthopaedics for foreign undergraduate medical students. At last year i taught Neurology for one batch. so i posted some of my collections for competely educational purpose coz i believe in knowledge ...inseted of deleting these ppts , they may me useful for others so i shared it ....
parkinson's disease by me ..........prakash mahala p.g. medical surgical nursing at himalayan college of nursing dehradun.......prakashjpmmahala@gmail.com
Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.
Module: Pharmacotherapy III
Module Coordinator: Dr. Arwa M. Amin Mostafa
Academic Level: Postgraduate, Master of Pharmacy in Clinical Pharmacy
School: Dubai Pharmacy College
Year of first presented in Class: 2018
This presentation is for Educational purpose. It has no commercial value associated with it.
This presentation deals with pathophysiology of Parkinson's Disease.
Important headings, including normal physiology, etiological factors and clinical manifestations have been elucidated.
parkinson's disease by me ..........prakash mahala p.g. medical surgical nursing at himalayan college of nursing dehradun.......prakashjpmmahala@gmail.com
Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.
Module: Pharmacotherapy III
Module Coordinator: Dr. Arwa M. Amin Mostafa
Academic Level: Postgraduate, Master of Pharmacy in Clinical Pharmacy
School: Dubai Pharmacy College
Year of first presented in Class: 2018
This presentation is for Educational purpose. It has no commercial value associated with it.
This presentation deals with pathophysiology of Parkinson's Disease.
Important headings, including normal physiology, etiological factors and clinical manifestations have been elucidated.
Parkinson’s disease is a neurodegenerative brain disorder. It is a kind of progressive disorder of the nervous system and hence no symptoms in most of the cases become obvious for many years.
Levodopa (also called L-dopa) is the most commonly prescribed medicine for Parkinson’s. It’s also the best at controlling the symptoms of the condition, particularly slow movements and stiff, rigid body parts.
Levodopa works when your brain cells change it into dopamine. That’s a chemical the brain uses to send signals that help you move your body. People with Parkinson’s don’t have enough dopamine in their brains to control their movements.
Sinemet is a mix of levodopa and another drug called carbidopa. Carbidopa makes the levodopa work better, so you can take less of it. That prevents many common side effects of levodopa, such as nausea, vomiting, and irregular heart rhythms.
Sinemet has the fewest short-term side effects, compared with other Parkinson’s medications. But it does raise your odds for some long-term problems, such as involuntary movements. An inhalable powder form of levopoda and the tablet istradefylline (Nourianz) have been approved for those experiencing OFF periods, OFF periods are when Parkinson’s symptoms return during periods between scheduled doses of levodopa/carbidopa.
People who take levodopa for 3-5 years may eventually have restlessness, confusion, or unusual movements within a few hours of taking the medicine. Changes in the amount or timing of your dose will usually prevent these side effects.
Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement
Parkinson's disease is a neurodegenerative disorder affecting movement, with symptoms such as tremors, stiffness, and difficulty with balance and coordination.
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June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
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The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
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Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
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2. Objectives
At the end of this presentation the students
will be able to learn about:
Definition of Parkinson's disease.
Signs and sym of Parkinson's disease.
Causes of Parkinson's disease.
Pathophysiology of Parkinson's disease.
Diadnose of Parkinson's disease.
Treatment of Parkinson's disease.
Nursing management of Parkinson's disease.
3. Definition
Parkinson's disease is a progressive disorder
of the nervous system that affects
movement. It develops gradually, sometimes
starting with a barely noticeable tremor in
just one hand. But while a tremor may be the
most well-known sign of Parkinson's disease,
the disorder also commonly causes stiffness
or slowing of movement.
4.
5. Signs and symptoms
Tremor.
Slowed movement (bradykinesia)
Rigid muscles.
Impaired posture and balance.
Loss of automatic movements.
Speech changes.
Writing changes.
6.
7. Causes
The cause of Parkinson's disease is unknown,
but several factors appear to play a role,
including:
Your genes. Researchers have identified
specific genetic mutations that can cause
Parkinson's disease, but these are uncommon
except in rare cases with many family
members affected by Parkinson's disease.
8. Causes
Environmental triggers. Exposure to certain
toxins or environmental factors may increase the
risk of later Parkinson's disease, but the risk is
relatively small.
The presence of Lewy bodies. Clumps of
specific substances within brain cells are
microscopic markers of Parkinson's disease.
These are called Lewy bodies, and researchers
believe these Lewy bodies hold an important
clue to the cause of Parkinson's disease.
9. Risk factors
Age. People usually develop the disease
around age 60 or older.
Heredity. Having a close relative with
Parkinson's disease increases the chances
that you'll develop the disease.
Sex. Men are more likely to develop
Parkinson's disease than are women
Exposure to toxins.
11. Pathophysiology
Parkinson’s disease is primarily associated with the
gradual loss of cells in the substantia nigra of the
brain.This area is responsible for the production of
dopamine. Dopamine is a chemical messenger that
transmits signals between two regions of the brain
to coordinate activity. For example, it connects the
substantia nigra and the corpus striatum to regulate
muscle activity. If there is deficiency of dopamine in
the striatum the nerve cells in this region “fire” out of
control.This leaves the individual unable to direct or
control movements.
12. Pathophysiology
.This leads to the initial symptoms of
Parkinson’s disease. As the nervous system
degenerate as well causing a more profound
movement disorder
13.
14. Diagnosis
No tests can conclusively show that you
have Parkinson's disease.Your doctor will
base a diagnosis on your symptoms,
medical history and a detailed physical
examination.
15. Diagnosis
The finding of Lewy bodies in the midbrain
on autopsy is usually considered final proof
that the person had PD.
People may be given levodopa, with any
resulting improvement in motor impairment
helping to confirm the PD diagnosis
16. Treatment
Parkinson's disease can't be cured, but
medications can help control your symptoms,
often dramatically. In some later cases,
surgery may be advised
Medications
Medications may help you manage problems
with walking, movement and tremor.These
medications increase or substitute for
dopamine, a specific signaling chemical
(neurotransmitter) in your brain.
17. Treatment
Carbidopa-levodopa.
Carbidopa-levodopa infusion.
Dopamine agonists.
MAO-B inhibitors.These medications include
selegiline (Eldepryl, Zelapar) and rasagiline
(Azilect).They help prevent the breakdown of
brain dopamine by inhibiting the brain enzyme
monoamine oxidase B (MAO-B).This enzyme
metabolizes brain dopamine.
Anticholinergics.
18. Surgical procedures
Deep brain stimulation. In deep brain
stimulation (DBS), surgeons implant
electrodes into a specific part of your brain.
The electrodes are connected to a generator
implanted in your chest near your collarbone
that sends electrical pulses to your brain and
may reduce your Parkinson's disease
symptoms.
19.
20. Nursing Interventions
Assess neurological status.
Assess ability to swallow and chew.
Provide high-calorie, high-protien, high-fiber
soft diet with small, frequent feedings.
Increase fluid intake to 2000 mL/day.
Monitor for constipation.
Promote independence along with safety
measures
21. Nursing Interventions
Administer antiparkinsonian medications to
increase the level of dopamine in the CNS.
Instruct the client to avoid foods high in
vitamin B6 because they block the effects of
antiparkinsonian medications.
22. References
Suchowersky O, et al. (2006). Practice
parameter: Neuroprotective strategies and
alternative therapies for Parkinson disease (an
evidence-based review).
http://www.neurology.org/content/66/7/968.f
ull.