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BY :-ANAS HARUNA INDABAWA
DEPARTMENT OF PHARMACY
SHIATS.
INTRODUCTION
About 2000 years ago, Hippocrates correctly
emphasized “Let food be your medicine and medicine
be your food". Currently there is an increased global
interest due to the recognition that “nutraceuticals” play
a major role in health enhancement. The term
"Nutraceutical" was coined by combining the terms
"Nutrition" and "Pharmaceutical" in 1989 by Dr
Stephen Defelice, Chairman of the Foundation for
Innovation in Medicine.
“Nutraceutical” is any substance that may be
considered as a food or part of food and provides
medical or health benefits, encompassing,
prevention and treatment of diseases.
Such products may range from isolated
nutrients, dietary supplements and diets to
genetically engineered "designer" foods, herbal
products and processed foods such as cereals,
soups and beverages.
NUTRACEUTICALS AND DISEASES
Nutraceuticals have been claimed to have a
physiological benefit or provide protection against the
following diseases(and/or found to act as)
 Cardiovascular agents
 Anti-obese agents
 Anti-diabetics
 Anticancer agents
 Immune boosters
 Chronic inflammatory disorders
 Degenerative diseases
1.Cardiovascular diseases
Cardiovascular diseases (CVD) is the
name for the group of disorders of the heart
and blood vessels and include hypertension
(high blood pressure), coronary heart disease
(heart attack), cerebrovascular disease (stroke),
heart failure, peripheral vascular disease, etc.
Flavonoids are widely distributed in onion,
cruciferous vegetables, black grapes,
grapefruits, apples, cherries and berries. All
these plays an important role in curing
cardiovascular diseases.
Milk and eggs are the important animal
sources of nutraceuticals, like proteins and
polyunsaturated fats or essential fatty acids
(EFAs). EFAs are required for production and
rebuilding of cells, to reduce blood pressure,
lower cholesterol and triglycerides,
Apple
Grapes Cherry
Onion
Milk
Egg
2- Obesity
Obesity, defined as an unhealthy amount of
body fat. It is a well-established risk factor for
many disorders like angina pectoris, congestive
heart failure, myocardial infarction ,
hypertension, hyperlipidaemia, respiratory
disorders, renal vein thrombosis, osteoarthritis,
cancer, reduced fertility etc.
One of the primary causes of rapid rise in obesity
rates is the increased availability of high-fat,
energy-dense foods.
A healthy diet can help in the following cases:
– Low fat diet may reduce the risk of heart
disease, diabetes and high blood pressure.
– A diet rich in fruits and vegetables provides
antioxidants (vitamins C, E and beta-carotene)
that protect the body against damage from free
radicals and reduces the risk of heart disease.
– Omega-3 and Omega-6, which are contained
in polyunsaturated fats (flax seeds, soybeans,
nuts and fish), may have a protective effect
against heart disease caused by obesity
Flax seed Soybeans
3- Diabetes
Diabetes mellitus is characterized by
abnormally high levels of blood glucose, either
due to insufficient insulin production, or due to
its ineffectiveness.
In other words, we can say that diabetes is
a continual metabolic disorder that prevents the
body from utilizing glucose totally or partially.
 Causes of Diabetes
-Insulin-dependent diabetes mellitus is mostly
outcome of a virus-initiated autoimmune destruction
of beta cells in the pancreas.
-Non-insulin-dependent diabetes mellitus can be
inherited and surface up with age or factors like
obesity, diet, lifestyle, inactivity, etc.
following are some dietary remedies to keep
control for diabetes like: beans, fish, citrus paradisi,
indian goose berry, string bean pod tea, red grape
fruit, blue berry, etc.
Citrus paradasi Beans
Indian gooseberry
4- Cancer
In the year 2000, malignant tumours were
responsible for 12 percent of the nearly 56 million
deaths worldwide from all causes. According to the
World Cancer report, cancer rates would be 15 million
new cases in the year 2020 i.e. a rise in 50%. Cancer
has emerged as a major public health problem in
developing countries.
Cancer is a group of diseases involving
abnormal cell growth with the potential to invade or
spread to other parts of the body.
Dietary recommendations for cancer
prevention typically include an emphasis on
vegetables, fruit, whole grains and fish, and an
avoidance of processed red meat (beef, pork,
lamb), animal fats, and refined carbohydrates.
People who consume large amount of
lutein-rich foods such as chicken eggs, spinach,
tomatoes, oranges and leafy greens experienced
the lowest incidence of colon cancer.
Spinach
Tomatoes
Cabbage
Fish
CONCLUSION
Nutraceuticals are currently receiving
recognition as being beneficial in coronary heart
disease, obesity, diabetes, cancer, osteoporosis and other
chronic and degenerative diseases such as Parkinson's
and Alzheimer's diseases. Evidences indicate that the
mechanistic actions of natural compounds involve a
wide array of biological processes, including activation
of antioxidant defences , signal transduction pathways,
cell proliferation and differentiation and preservation of
mitochondrial integrity.
REFERENCES:
 Brower V. Nutraceuticals: poised for a healthy slice of the
healthcare market? Nat Biotechnol. 199; 16: 728-731.
Eskin N A M and Tamir S Dictionary of Nutraceuticals
and Functional Foods, CRC Press, Boca Raton, USA.
2006.
Rajesekaran A, Sivagnanam G, Xanvier R; Nutraceuticals
as therapeutic agents;2008.
Temple WJ and Gladwin KK. Fruits, vegetables, and the.
Prevention of cancer: Research challenges. Nutrition.
2003; 19: 467-470.
THANK YOU

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Nutraceuticals in dietary therapy copy

  • 1. BY :-ANAS HARUNA INDABAWA DEPARTMENT OF PHARMACY SHIATS.
  • 2. INTRODUCTION About 2000 years ago, Hippocrates correctly emphasized “Let food be your medicine and medicine be your food". Currently there is an increased global interest due to the recognition that “nutraceuticals” play a major role in health enhancement. The term "Nutraceutical" was coined by combining the terms "Nutrition" and "Pharmaceutical" in 1989 by Dr Stephen Defelice, Chairman of the Foundation for Innovation in Medicine.
  • 3. “Nutraceutical” is any substance that may be considered as a food or part of food and provides medical or health benefits, encompassing, prevention and treatment of diseases. Such products may range from isolated nutrients, dietary supplements and diets to genetically engineered "designer" foods, herbal products and processed foods such as cereals, soups and beverages.
  • 4. NUTRACEUTICALS AND DISEASES Nutraceuticals have been claimed to have a physiological benefit or provide protection against the following diseases(and/or found to act as)  Cardiovascular agents  Anti-obese agents  Anti-diabetics  Anticancer agents  Immune boosters  Chronic inflammatory disorders  Degenerative diseases
  • 5. 1.Cardiovascular diseases Cardiovascular diseases (CVD) is the name for the group of disorders of the heart and blood vessels and include hypertension (high blood pressure), coronary heart disease (heart attack), cerebrovascular disease (stroke), heart failure, peripheral vascular disease, etc.
  • 6. Flavonoids are widely distributed in onion, cruciferous vegetables, black grapes, grapefruits, apples, cherries and berries. All these plays an important role in curing cardiovascular diseases. Milk and eggs are the important animal sources of nutraceuticals, like proteins and polyunsaturated fats or essential fatty acids (EFAs). EFAs are required for production and rebuilding of cells, to reduce blood pressure, lower cholesterol and triglycerides,
  • 9. 2- Obesity Obesity, defined as an unhealthy amount of body fat. It is a well-established risk factor for many disorders like angina pectoris, congestive heart failure, myocardial infarction , hypertension, hyperlipidaemia, respiratory disorders, renal vein thrombosis, osteoarthritis, cancer, reduced fertility etc.
  • 10. One of the primary causes of rapid rise in obesity rates is the increased availability of high-fat, energy-dense foods. A healthy diet can help in the following cases: – Low fat diet may reduce the risk of heart disease, diabetes and high blood pressure. – A diet rich in fruits and vegetables provides antioxidants (vitamins C, E and beta-carotene) that protect the body against damage from free radicals and reduces the risk of heart disease.
  • 11. – Omega-3 and Omega-6, which are contained in polyunsaturated fats (flax seeds, soybeans, nuts and fish), may have a protective effect against heart disease caused by obesity Flax seed Soybeans
  • 12. 3- Diabetes Diabetes mellitus is characterized by abnormally high levels of blood glucose, either due to insufficient insulin production, or due to its ineffectiveness. In other words, we can say that diabetes is a continual metabolic disorder that prevents the body from utilizing glucose totally or partially.
  • 13.  Causes of Diabetes -Insulin-dependent diabetes mellitus is mostly outcome of a virus-initiated autoimmune destruction of beta cells in the pancreas. -Non-insulin-dependent diabetes mellitus can be inherited and surface up with age or factors like obesity, diet, lifestyle, inactivity, etc. following are some dietary remedies to keep control for diabetes like: beans, fish, citrus paradisi, indian goose berry, string bean pod tea, red grape fruit, blue berry, etc.
  • 15. 4- Cancer In the year 2000, malignant tumours were responsible for 12 percent of the nearly 56 million deaths worldwide from all causes. According to the World Cancer report, cancer rates would be 15 million new cases in the year 2020 i.e. a rise in 50%. Cancer has emerged as a major public health problem in developing countries. Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
  • 16. Dietary recommendations for cancer prevention typically include an emphasis on vegetables, fruit, whole grains and fish, and an avoidance of processed red meat (beef, pork, lamb), animal fats, and refined carbohydrates. People who consume large amount of lutein-rich foods such as chicken eggs, spinach, tomatoes, oranges and leafy greens experienced the lowest incidence of colon cancer.
  • 18. CONCLUSION Nutraceuticals are currently receiving recognition as being beneficial in coronary heart disease, obesity, diabetes, cancer, osteoporosis and other chronic and degenerative diseases such as Parkinson's and Alzheimer's diseases. Evidences indicate that the mechanistic actions of natural compounds involve a wide array of biological processes, including activation of antioxidant defences , signal transduction pathways, cell proliferation and differentiation and preservation of mitochondrial integrity.
  • 19. REFERENCES:  Brower V. Nutraceuticals: poised for a healthy slice of the healthcare market? Nat Biotechnol. 199; 16: 728-731. Eskin N A M and Tamir S Dictionary of Nutraceuticals and Functional Foods, CRC Press, Boca Raton, USA. 2006. Rajesekaran A, Sivagnanam G, Xanvier R; Nutraceuticals as therapeutic agents;2008. Temple WJ and Gladwin KK. Fruits, vegetables, and the. Prevention of cancer: Research challenges. Nutrition. 2003; 19: 467-470.