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Noise2Score: Tweedie’s Approach to Self-Supervised Imag
e Denoising without Clean Images
Kwanyoung Kim, Jong Chul Ye
Bio Imaging, Signal Processing & Learning Lab
@KAIST
Supervised Learning Approaches
• CNN as a direct inverse operation
• Most simplest and fastest method
• Supervised learning with lots of data
: feed-forward network
Self-Supervised
Feed-forward CNN?
Noise2Noise
Input Target
Output
L2 loss
Self-Supervised Learning: Noise2X
Lehtinen et al, ICML 2018
Input Target
L2 loss
Output
Noise2Self
Self-Supervised Learning: Noise2X
Batson et al, ICML 2019
Self-Supervised Learning: SURE
Soltanayev et al, NeurIPS, 2018
Self-supervised denoising using Stein Unsupervised Risk Estimator (SURE)
Divergence-based
penalty
Autoencoder loss
Supervised learning, Noise2X, SURE
Supervised learning
Noise2X : Noise2Noise, Noise2Self, Noise2Void, etc.
:samples of the noisy-clean image pair for training data
: target z is related to in unique ways depending on algorithms.
 most of the algorithmic choices are heuristic
SURE
: divergence penalty is added to compensate for use of y
Any unified mathematical
framework?
Yes! Noise2Score
Score function
Noise2X, SURE Noise2Score
Kim and Ye, NeurIPS, 2021
Tweedie’s formula for general exponential family
• Using the Bayes’ rule, the posterior density:
• Probability distribution of exponential family:
B Efron, Journal of the American Statistical Association, 2011
Tweedie’s formula for general exponential family
• The closed form solution for the posterior mean:
• Bayes optimal solution  posterior mean
Case1. Gaussian noise
• Tweedie’s formula calculates the posterior mean of x given y.
• Gaussian noise removal
Score function
Proof:
Case2. Poisson noise
Case3. Gamma noise
Tweedie’s formula of exponential family distribution for
image denoising
As long as we can compute the score function,
optimal denoising can be achieved by using Tweedie’s formula.
How to estimate the
score function?
Score function
Training data
≃
Score function
Score model
Figure courtesy from https://yang-song.github.io/blog/2021/score/
Score matching
Figure courtesy from https://yang-song.github.io/blog/2021/score/
Hyvärinen et al, JMLR, 2005
Score matching
Figure courtesy from https://yang-song.github.io/blog/2021/score/
Denoising Score matching
Figure courtesy from https://yang-song.github.io/blog/2021/score/
Denoising Autoencoder (DAE)
• DAE is to learn to recover data from the perturbed data
• DAE can be used to estimate the score function of data
Alain et al, JMLR, 2014
Equal to Tweedie’s formula for Gaussian noises
Amortized – Residual DAE (AR-DAE)
• The residual from of the DAE:
• Addresses instability and reduce approximation error
• Directly estimate the score function:
Lim et al, ICML, 2020
Relation to SURE
By using AR-DAE transform
Score matching cost by Hyvärinen et al, JMLR, 2005
Noise2Score
Score function
Kim and Ye, NeurIPS, 2021
Conclusion
• Noise2Score: a novel unified framework for self-supervised image
denoising.
• Our Noise2Score can be applied to any image denoising problem from
exponential family noises.
• Identical neural network training can be used regardless of noise model.
Thank you!
Jong Chul Ye
E-mail:
jong.ye@kaist.ac.kr
Kwanyoung Kim
E-mail:
cubeyoung@kaist.ac.kr

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Noise2Score: Tweedie’s Approach to Self-Supervised Image Denoising without Clean Images

Editor's Notes

  1. 그런데 지금까지의 연구는 대부분의 경우 과화질의 레이블의 영상이 존재화고 저화질의 측정 데이타가 있을떄 이를 지도학습의 기반으로 복원하는것이었는데, 만약에 고화질의 영상이 존재하지 않을경우는 어떤게 딥네트워크를 훈련하여 사용할수 있을까요?
  2. 그런데 지금까지의 연구는 대부분의 경우 과화질의 레이블의 영상이 존재화고 저화질의 측정 데이타가 있을떄 이를 지도학습의 기반으로 복원하는것이었는데, 만약에 고화질의 영상이 존재하지 않을경우는 어떤게 딥네트워크를 훈련하여 사용할수 있을까요?
  3. 지금까지 본 발표에서는 GAN이 의료영상 복원에서 비지도 학습기법으로 점점도 중요한 주제가 되고 있다는것을 보였고, 특히 collaGAN은 MR contrast 의 연구에 사용이 가능하다는것을 보였습니다. 경청해주셔서 감사합닏.