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Nm disorder

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This document discusses several neuromuscular disorders including poliomyelitis, amyotrophic lateral sclerosis, neuropathies, myopathies, myasthenia gravis, diseases of the neuromuscular junction, botulism, tick paralysis, thyrotoxic periodic paralysis, and familial periodic paralysis. It provides details on clinical presentation, pathogenesis, diagnostic testing, and management for each condition.

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Neuromuscular Disorders Saad Al Juma R3
In MNL : ,[object Object],[object Object],[object Object],[object Object]
In MNL : ,[object Object],[object Object],[object Object],[object Object]
In Amyotrophic lateral sclerosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
In Amyotrophic lateral sclerosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
In MNL all are true except : ,[object Object],[object Object],[object Object],[object Object]
In MNL : ,[object Object],[object Object],[object Object],[object Object]
In Neuropathies , all are true EXCEPT : ,[object Object],[object Object],[object Object],[object Object]
In Neuropathies : ,[object Object],[object Object],[object Object],[object Object]
In Myopathies , all are true EXCEPT : ,[object Object],[object Object],[object Object],[object Object]
In Myopathies ,[object Object],[object Object],[object Object],[object Object]
DISEASE HISTORY STRENGTH DEEP TENDON REFLEX SENSATION WASTING Myelopathy Trauma, infection, cancer Normal to decreased Increased Normal to decreased No Motor neuron disease (ALS) Progressive difficulty swallowing, speaking, walking Decreased Increased Normal Yes Neuropathy   Recent infection Ascending weakness Normal or decreased Distal > proximal Decreased   Decreased   Yes   Neuromuscular junction disease Food (canned goods) Tick exposure Easy fatigability Normal to fatigue     Normal     Normal     No     Myopathy   Thyroid disease Previous similar episodes Decreased Proximal > distal Normal   Normal   Yes  
In MG all the following are true except : ,[object Object],[object Object],[object Object],[object Object]
In MG : ,[object Object],[object Object],[object Object],[object Object]
In Diseases of the Neuromuscular Junction Repeated stimulation leads to diminishing motor strength, which is caused by : ,[object Object],[object Object],[object Object],[object Object]
In Diseases of the Neuromuscular Junction Repeated stimulation leads to diminishing motor strength, which is caused by : ,[object Object],[object Object],[object Object],[object Object]
decrease in the release of ACh may produce except ,[object Object],[object Object],[object Object],[object Object],[object Object]
decrease in the release of ACh may produce: ,[object Object],[object Object],[object Object],[object Object],[object Object]
All are true about Myopathies , except : ,[object Object],[object Object],[object Object],[object Object],[object Object]
All are true about Myopathies : ,[object Object],[object Object],[object Object],[object Object],[object Object]
Lambert-Eaton myasthenic syndrome all are false except : ,[object Object],[object Object],[object Object],[object Object]
Lambert-Eaton myasthenic syndrome : ,[object Object],[object Object],[object Object],[object Object]
Regarding MG , all are true except : ,[object Object],[object Object],[object Object],[object Object]
Regarding MG : ,[object Object],[object Object],[object Object],[object Object]
 
What is Edrophonium test ?
What is Edrophonium test ? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],reports of FP with botulism
What is Ice pack test ?
What is Ice pack test ? ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],In Myasthenic Crisis all are true Except :
In Myasthenic Crisis : ,[object Object],[object Object],[object Object],[object Object]
 
Medications precipitate MG crisis
Medications precipitate MG crisis CVS ABX Others Beta-blockers Aminoglycosides Phenytoin Calcium channel blockers Tetracyclines Neuromuscular blockers Quinidine Clindamycin Corticosteroids Lidocaine Lincomycin Thyroid replacement Procainamide Polymyxin B Colistin
Regarding MG Management all are true EXCEPT : ,[object Object],[object Object],[object Object],[object Object]
Regarding MG Management: ,[object Object],[object Object],[object Object],[object Object]
Regarding P.E in M.G : ,[object Object],[object Object],[object Object],[object Object]
Regarding P.E in M.G : ,[object Object],[object Object],[object Object],[object Object]
Regarding Botulism , all are true except : ,[object Object],[object Object],[object Object],[object Object]
Regarding Botulism : ,[object Object],[object Object],[object Object],[object Object]
In Botulism , all are true except : ,[object Object],[object Object],[object Object],[object Object],[object Object]
In Botulism : ,[object Object],[object Object],[object Object],[object Object],[object Object]
Regarding Botulisim antitoxin ,[object Object],[object Object],[object Object],[object Object],[object Object]
Regarding Botulisim antitoxin ,[object Object],[object Object],[object Object],[object Object]
In Tick Paralysis , all are true except ,[object Object],[object Object],[object Object],[object Object]
In Tick Paralysis ,[object Object],[object Object],[object Object],[object Object]
In Thyrotoxic Periodic Paralysis , all are true EXCEPT : ,[object Object],[object Object],[object Object],[object Object]
In Thyrotoxic Periodic Paralysis ,[object Object],[object Object],[object Object],[object Object]
In Familial Periodic Paralysis all are true EXCEPT : ,[object Object],[object Object],[object Object],[object Object],[object Object]
In Familial Periodic Paralysis : ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
 
 
 
Which of the following statements is true? ,[object Object],[object Object],[object Object],[object Object],[object Object]
The answer is c. ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The answer is b ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The answer is d ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The answer is c ,[object Object]
Curare ( Chondodendron tomentosum ), ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The answer is a ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lambert-Eaton Myasthenic Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Myasthenia Gravis ,[object Object]

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Nm disorder

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  • 12. DISEASE HISTORY STRENGTH DEEP TENDON REFLEX SENSATION WASTING Myelopathy Trauma, infection, cancer Normal to decreased Increased Normal to decreased No Motor neuron disease (ALS) Progressive difficulty swallowing, speaking, walking Decreased Increased Normal Yes Neuropathy   Recent infection Ascending weakness Normal or decreased Distal > proximal Decreased   Decreased   Yes   Neuromuscular junction disease Food (canned goods) Tick exposure Easy fatigability Normal to fatigue     Normal     Normal     No     Myopathy   Thyroid disease Previous similar episodes Decreased Proximal > distal Normal   Normal   Yes  
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  • 26. What is Edrophonium test ?
  • 27.
  • 28. What is Ice pack test ?
  • 29.
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  • 32.  
  • 34. Medications precipitate MG crisis CVS ABX Others Beta-blockers Aminoglycosides Phenytoin Calcium channel blockers Tetracyclines Neuromuscular blockers Quinidine Clindamycin Corticosteroids Lidocaine Lincomycin Thyroid replacement Procainamide Polymyxin B Colistin
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