This document discusses biosensors and nanobiosensors. It begins by defining biosensors as sensors that integrate a biological recognition element with a physiochemical transducer. It then describes the three main components of a biosensor: the recognition element, transducer, and signal processor. The document outlines different types of biosensors including electrochemical, optical, mass-based, and colorimetric. It also discusses the principles of detection for each type. Nanobiosensors are described as having characteristics like sensitivity, specificity, portability, and versatility. Current research highlighted includes wearable nanobiosensors to monitor health and implantable versions to continuously measure analytes like glucose. Applications of nanobiosensors span fields like medical diagnostics
The revolution of nanotechnology in molecular biology gives an opportunity to detect and manipulate atoms and molecules at the molecular and cellular level.
The revolution of nanotechnology in molecular biology gives an opportunity to detect and manipulate atoms and molecules at the molecular and cellular level.
A sensor that integrates a biological element with a physiochemical transducer to produce an electronic signal proportional to a single analyte which is then conveyed to a detector.
A part of nanotechnology. Nanosensors is very hot topic for research. As nanosensor has immense applications in the fields like medical, analysis, research etc. Nanosensor recude the cost and also the time require for analysis.
This ppt is about biosensors. A brief Introduction to biosensors, history of Biosensors, working of biosensors, usage of biosensors application of biosensors in medical and other fields
A sensor that integrates a biological element with a physiochemical transducer to produce an electronic signal proportional to a single analyte which is then conveyed to a detector.
A part of nanotechnology. Nanosensors is very hot topic for research. As nanosensor has immense applications in the fields like medical, analysis, research etc. Nanosensor recude the cost and also the time require for analysis.
This ppt is about biosensors. A brief Introduction to biosensors, history of Biosensors, working of biosensors, usage of biosensors application of biosensors in medical and other fields
Biosensors, Types of Biosensors, Applications of Biosensors, Nanotechnology, Nanobiosensors, Components of Biosensor, Working of Biosensor, Principle of Biosensor, Examples of Biosensor, Advantages of Biosensor, Disadvantages of Biosensor, Limitations of Biosensor, Features of a Biosensor, Calorimetric Biosensors, Potentiometric Biosensors, Acoustic Wave Biosensors, Amperometric Biosensors, Optical Biosensors, Examples of a Nanobiosensor, Lab on a chip,
Applications of Lab on a chip, Glucose Biosensor
Biosensors: General Principles and ApplicationsBhatt Eshfaq
A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector.
Biosensors are the analytical device that are used to measure the concentration of analye , these type of biosensors are made with conjugation of enzymes as a biological eliment to quantify a (bio)chemical substance / analyte are reffered to as Enzyme-probe Biosensors .
Biosensors are of many types but focusing on Enzyme biosensors there are 4 main types which are briefly described in this power point presentation .
Biosensor and its Applications.
Biosensors are analytical devices that combine a biological component with a physicochemical detector to provide specific and sensitive detection of target analytes.
Importance: Biosensors have revolutionized the way we detect and monitor various substances, from biomarkers to environmental pollutants.
Biosensor is an leading Biological technology now. It is an application of Biotechnology. It makes laboratory tests more fast and easy to carry out. It is cost effective, more accurate precise, and have less errors.
Food safety ( Basic steps in detection of food borne pathogens )SurbhiRai8
It consists of basic structure of steps for analysis of food borne pathogens in various ways and about these ways . what do we mean by food borne pathogens and why there is a need for their detection . then it has a little brief about each and every method . then we have covered 4 basic pathogens found in food and their detection methods . we are very thankful for all the sources from which we got this data . some of them are research papers and google books but it helped us to learn more .
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
2. CONTENTS
Sensors, Biosensors& Nano Biosensors
History
Definition
Constituents
Types
Principle of detection
Characteristics
Nanobiosensor system
Nano materials
Cancer detection
Application
Current research
5. BIOSENSORS ARE EVERYWHERE
◦ Monitors the blood glucose level in the
blood
◦ device helps patients maintain their blood
glucose readings without the pain
associated with traditional injections.
Glucose monitoring
device (for
diabetic patient)
8. FATHER OF NANO BIOSENSORS
Professor Leland C
Clark Jnr( 1918–
2005)
9. Current Definition of Nano Biosensors
A sensor that integrates a biological
element with a physiochemical transducer
to produce an electronic signal proportional to
a single analyte which is then conveyed to a
detector
10. BIOSENSOR IS MADE UP OF
3COMPONENT
a recognition element/ Analyte (What do
you want to detect)
Molecule - Protein, toxin, peptide, vitamin,
sugar, metal ion
a signal transducer.(to convert biological
response to an electric signal)
a signal processor that relays and displays
the results(How do you know there was a
detection)
13. ELECTROCHEMICAL
BIOSENSORS
Many chemical reaction produce or consume
ions or electrons causing some change in the
electric properties of the solution that can be
sensed out and used as a measuring
parameter.
Uses: Detection of:
Hybridized DNA
DNA-Binding drugs
Glucose detection.
14. OPTICAL BIOSENSORS
Colorimetric for color
◦ Measure change in light adsorption
Photometric for light intensity
◦ Photon output for a luminescent or
fluorescent process can be detected
with photomultiplier tubes or
photodiode systems.
15. MASS-BASED BIOSENSORS
Piezoelectric sensors are based on
changes in the mass of quartz crystals
when potential energy is applied to
them. This change in mass generates
a frequency, which can be converted
into a signal.
16. COLORIMETRIC BIOSENSORS
Calorimetric biosensors measure
exothermic reactions.
Many enzymatic reactions generate
heat, and changes in heat can be
used to measure analyte
concentration.
Monitored by measuring enthalpy
changes
17. PRINCIPLES OF DETECTION
PIEZO- ELECTRIC Measures change in Mass
ELECTROCHEMICAL Measures change in Electric
distribution
◦
OPTICAL Measures change in Light intensity
COLORIMETRIC Measures change in Heat
22. NANO NOSE SMELLS CANCER
Cancer is defined as abnormal and
uncontrolled cell growth due to both
environmental and hereditary defects.
By measuring levels of certain proteins
secreted by tumor cells, in urine.
whether a tumor is present,
whether it benign or cancerous,
whether treatment has been effective in
reducing or eliminating cancerous cells.
23. DIAGNOSIS OF CANCER BY:
MRI(magnetic resonance imaging)
Drawback: can’t detect entities smaller
than few cm.
NANOMATRIALS( 1to100nm) in
diameter)
Liposomes
Dendrimers
Bucky balls
Carbon nanotubes
Quantum dots
24. • Food Analysis
• Study of biomolecules and their interaction
• Drug Development
• Medical diagnosis
• Environmental field monitoring
• Quality control
• Industrial Process Control
• Detection systems for biological warfare agents
• Manufacturing of pharmaceuticals and
replacement organs
APPLICATION OF NANO BIOSENSORS
25. CURRENT RESERCH ( WEARABLE)
•Activated when sufficient sweat is detected.
•Measures metabolite& Electrolyte level of
healthy person.
•Alert- Dehydration, Fatigue &Rising body temp.
26. CURRENT RESERCH ( IMPLANTABLE )
•Measures glucose
level.
•Hyperglycemia
triggers the delivery
of Metformin (type 2)
•Patch can connect
to portable analyser
(Wireless data
transmitter).
•Data can be sent to
Smartphone or
tablet.
