2. What are biosensors?
Devices that analyze biological samples to better understand
structure and function and for diagnostics
Uses for biosensors
Molecule analysis (DNA and proteins)
Food safety
Diagnostics
Medical monitoring
Detection of biological weapons
3. Dr. Leland Clark Jr
“Father of the biosensor”
History of Biosensors
First described in 1962 by Dr. Leland Clark
1969, a sensor was invented to detect urea
4. COMPONENTS OF BIOSENSOR; 4
A biosensor consists of two components:
Bioreceptor and
Transducer.
The bioreceptor is a biomolecule that recognizes
the target analyte
The transducer converts the recognition event into a
measurable signal.
7. Biosensors
Advantages
Rapid detection
Small volumes of samples needed
Can be used by the patient (blood glucose monitor)
Disadvantages
Cost
May require expertise to use
Sample collection can be painful
9. PIEZO-ELECTRIC BIOSENSORS
• Also called acoustic wave biosensor.
. Their surface is coated with antibodies which
binds to complimentary antigen present in
sample solution .
10. OPTICAL BIOSENSORS
•Colorimetric for color
Measure change in light adsorption
•Photometric for light intensity
Photon output for a luminescent or
fluorescent process can be detected
with photomultiplier tubes or
photodiode systems.
11. AMPERIOMETRIC BIOSENSORS
These electrodes functions by the
production of a current when potential is
applied between two electrodes ,the
magnitude of current is being
propotional to substrate concenteration