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BY
PARTHIPAN S
2014010015
1
What are biosensors?
 Devices that analyze biological samples to better understand
structure and function and for diagnostics
 Uses for biosensors
 Molecule analysis (DNA and proteins)
 Food safety
 Diagnostics
 Medical monitoring
 Detection of biological weapons
Dr. Leland Clark Jr
“Father of the biosensor”
History of Biosensors
 First described in 1962 by Dr. Leland Clark
 1969, a sensor was invented to detect urea
COMPONENTS OF BIOSENSOR; 4
A biosensor consists of two components:
Bioreceptor and
Transducer.
 The bioreceptor is a biomolecule that recognizes
the target analyte
 The transducer converts the recognition event into a
measurable signal.
Schematic illustration of a Biosensor
6
signal prossing monitoramplificationtransducerbioreceptor
Biosensors
 Advantages
 Rapid detection
 Small volumes of samples needed
 Can be used by the patient (blood glucose monitor)
 Disadvantages
 Cost
 May require expertise to use
 Sample collection can be painful
Types of Biosensors
1. Calorimetric Biosensor
2. Potentiometric Biosensor
3. Amperometric Biosensor
4. Optical Biosensor
5. Piezo-electric Biosensor
PIEZO-ELECTRIC BIOSENSORS
• Also called acoustic wave biosensor.
. Their surface is coated with antibodies which
binds to complimentary antigen present in
sample solution .
OPTICAL BIOSENSORS
•Colorimetric for color
Measure change in light adsorption
•Photometric for light intensity
Photon output for a luminescent or
fluorescent process can be detected
with photomultiplier tubes or
photodiode systems.
AMPERIOMETRIC BIOSENSORS
These electrodes functions by the
production of a current when potential is
applied between two electrodes ,the
magnitude of current is being
propotional to substrate concenteration
Potentiometric Biosensor
These biosensors convert biological
reactions into electric signals
Common biosensors
 Blood glucose monitors
 Heart and blood pressure monitors
 Pacemakers
 HIV and pregnancy tests
Blood glucose monitors
 Used by diabetics to measure blood glucose concentration
 Helps patients determine their insulin dose
Pregnancy test
Detects the hCG protein in urine.
Glucose monitoring device (for diabetes patients)
Monitors the glucose level in the blood.
WEARABLE BIOSENSORS
 Google smart lens
 Q sensor
 Wearable glucose sensor
 Simband wearable biosensor
 Wearable biosensor tattoos monitor sweat to track weight
Google smart lens
Q sensor
Wearable glucose sensor
Simband wearable biosensor
Wearable biosensor tattoos monitor sweat
to track weight
Application of Biosensor
THANK YOU

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components of biosensors