The document provides an overview of mechanical ventilation using the Medumat Standard 2 ventilator. It discusses the ventilator's modes of ventilation including IPPV, CPAP, BiPAP, PCV, SIMV, and PRVC. It also covers initial setup based on patient height and weight, ventilator strategies, adjusting settings to optimize oxygenation and ventilation, ventilator curves and alarms, troubleshooting, and the use of non-invasive ventilation with CPAP and BiPAP modes. The primary mode discussed for most patients is IPPV, and adjustments to settings like respiratory rate and PEEP/FiO2 are recommended to maintain normocarbia and optimal oxygenation.
Created by:
Rob Chatburn, RRT RRT-NPS, FAARC
Research Manager – Respiratory Therapy
Cleveland Clinic
Associate Professor
Case Western Reserve University
This is a presentation covers the basics aspects of dual mode of mechanical ventilations. these modes that use the pressure control and volume control ventilation at the same time.
Created by:
Rob Chatburn, RRT RRT-NPS, FAARC
Research Manager – Respiratory Therapy
Cleveland Clinic
Associate Professor
Case Western Reserve University
This is a presentation covers the basics aspects of dual mode of mechanical ventilations. these modes that use the pressure control and volume control ventilation at the same time.
Presented by Dr.Andres Esteban at Pulmonary Medicine Update Course 2009 at Cairo, Egypt.
Pulmonary Medicine Update Course is organized by Scribe . www.scribeofegypt.org
Presentation of Dr.Lluis Blanch at Pulmonary Critical Care Egypt 2014 , January2014, the leading critical care conference and medical exhibition in Egypt.www.pccmegypt.com
Presentation of Dr. Dean Hess at 10th Pulmonary Medicine Update Course, Cairo, Egypt. Pulmonary Medicine Update Course is organized by Scribe : www.scribeofegypt.com
Presented by Dr.Andres Esteban at Pulmonary Medicine Update Course 2009 at Cairo, Egypt.
Pulmonary Medicine Update Course is organized by Scribe . www.scribeofegypt.org
Presentation of Dr.Lluis Blanch at Pulmonary Critical Care Egypt 2014 , January2014, the leading critical care conference and medical exhibition in Egypt.www.pccmegypt.com
Presentation of Dr. Dean Hess at 10th Pulmonary Medicine Update Course, Cairo, Egypt. Pulmonary Medicine Update Course is organized by Scribe : www.scribeofegypt.com
Learning Objectives Covered1. Explain Respiratory Failure and th.docxsmile790243
Learning Objectives Covered
1. Explain Respiratory Failure and the two types of respiratory failure: hypoxemic and hypercapnic respiratory failure
2. List and describe the indications and objectives for ventilator support
3. Explain the advantages and disadvantages of volume and pressure ventilation>
Background
Mechanical Ventilation is indicated to assist the patient who cannot maintain adequate oxygenation, alveolar ventilation or lacks the ability to protect his or her own airway.The inability of a patient to maintain either the normal delivery of oxygen to the tissues or the normal removal of carbon dioxide from the tissues is referred to as acute respiratory failure. Though the three common indications for mechanical ventilation includes inability to maintain adequate oxygenation, inability to maintain adequate alveolar ventilation and/or inability to protect one’s own airway. There are more specific indications for mechanical ventilation and can be found in the table below.
Indications
Definition
Example
Apnea
Absence of breathing
Cardiac Arrest
Acute
Respiratory Failure (ARF)
Inability of a patient to maintain adequate: PaO2, PaCO2, and, potentially, pH.
Hypoxemic RF
Hypercapnic RF
Impending
Respiratory Failure
Respiratory failure is immi-nent in spite of therapies.
Commonly defined as: Pt is barely maintaining (or gradually deteriorating) normal blood gases but with significant WOB.
Neuromuscular
Disease (N-M)
Status Asthmaticus
Chronic
Respiratory Failure
Repeated failures after attempts to liberate from the ventilator (extubations, Trach Collar trials, etc.)
SEVERE:
Obesity Hypoventilation Syndrome
COPD
Pulmonary Fibrosis
Prophylactic
Ventilatory Support
Clinical indication = high risk of respiratory failure.
Ventilatory support is instituted to ↓ WOB,minimize O2consumption and hypoxemia, reduce cardiopulmonary stress, and/or control airway with sedation.
Brain injury
Heart muscle
Injury
Major surgery
Shock (prolonged)
Smoke injury
Trauma (some)
Hyperventilation Therapy
Ventilatory support is instituted to control and manipulate PaCO2 tor lower than normal level
Acute head injury
(↑ ICP)
(not immediately
after injury)
*respiratoryupdate.com
Respiratory failure can be acute or chronic and is classified as either hypoxemic or hypercapnic. During hypoxemic respiratory failure, the patient’s ventilatory demands exceed the lung's ability to provide blood oxygenation resulting in muscle fatigue. Hypoxemic respiratory failure is defined as a PaO2 below the predicted normal range for the patient’s age under ambient conditions. A normal PaO2 for a patient that is 60 years or younger on room air is 80-100mmHg. When a patient is hypoxemic their body naturally responds to the low PaO2by increasing respiratory rate and/or tidal volume (an increase in minute ventilation). An increase in minute ventilation leads to hyperventilation. During hyperventilation, a greater than normal amount of CO2 is exhaled resulting in a low PaCO2 (h ...
Ventilator Hyperinflation (VHI) is a physiotherapy intervention that enables the deliverance of larger than baseline tidal volumes (Vt) via adjustment of the ventilator in the intubated and ventilated patient.
Ventilator hyperinflation (VHI) is a technique used by physiotherapists in intensive care patients who are receiving mechanical ventilation. The aims of VHI are similar to that of manual hyperinflation (MHI) and are primarily implemented in order to improve respiratory function by mobilising secretions and restoring lung volume. Since first being described in the literature in 2002
the use of VHI techniques has increased, with recent surveys suggesting they are utilised within 20% to 40% of tertiary hospitals
Despite this interest, there has been little research into VHI to guide education and practice. Clinical studies that have investigated VHI techniques have all utilised different methods to deliver the technique and there is considerable variability among clinicians in how VHI is delivered
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
2. Introduction
• With the purchase of a modern transport ventilator we are able to
offer improved control and monitoring of ventilation to our patients.
The following presentation seeks to introduce these capabilities to
you in an operational and clinical context.
• The presentation is meant to be used in conjunction with provided
independent study materials and education program which will help
us get better at ventilation but also get better at ventilation with our
new equipment.
3. Modes of Ventilation
3
The Standard 2 is able to provide the following modes of Mechanical
Ventilation.
-IPPV
-CPAP
-BiPAP
-PCV
-SIMV
-PRVC
Currently the vast majority of our patients are sedated/paralyzed and
the most appropriate mode to use is IPPV. IPPV is a mandatory
volume controlled mode and is functionally the same as the mode
used on our previous generation of ventilators. All “emergency
modes” utilize IPPV as the default ventilation mode.
4. Initial Set-Up
4
Calculating the approximate height of the adult patient is
important as the ventilator will calculate the optimal tidal
volume based on IDEAL BODY Weight (IDW) which is a
function of height
IBW=50 + (0.9 x Ht-152.4)
A reasonable Tidal Volume is 6-8 ml/kg
For toddlers and young children under 124 cm
ideal tidal volumes are based on approximate
weight
Tidal Volume= 10ml/kg
The Standard 2 Ventilator cannot deliver accurate
tidal volumes below 85 ml
5. Ventilator Strategies
• The majority of our patients can be managed with a “lung-protective” ventilation
strategy. This strategy aims to prevent barotrauma by limiting tidal volume.
• Patients with obstructive lung disease may require a different approach to
ventilation and are at higher risks of complications due to ongoing
bronchoconstriction. The respiratory rate and I:E ratio can be titrated to allow
time for the patient to exhale
6. Adjusting our Settings
• Effective Ventilation and Oxygenation requires regular re-assessment
of the patient AND the ventilator
• In the absence of impending complications we should consider adjusting our
vent to optimize EtC02 & Oxygenation
• In general our goal is normocarbia and assuming a fixed tidal volume adjustment of the
respiratory rate can accomplish that
• Both hyperoxia and hypoxia are undesirable. Adjustment of PEEP and Fi02 can help
maintain this balance. The Standard 2 is only able to provide “Air-Mix” or 100% Oxygen
7. Emergency Modes
• The Weinneman Standard 2 comes with 3 “Emergency Modes” these are ventilation modes which
automatically initiate IPPV for a standardized patient. The ARHT Ventilators “Emergency Modes”
will be customized to mirror recommendations in the SJA CPGS and are suitable for our “standard
patients”
Emergency
Mode
ADULT CHILD (25 KG) PEDIATRIC (12.5 KG)
VT 600 200 100
Frequency 12 20 30
I:E Ratio 1:2 1:2 1:2
PEEP 5 5 0
P Max 40 35 30
8. Display Curves
• Unlike our current modules which have an analog pressure gauge only, the Standard 2 is able to
provide a digital Pressure Gauge, a Pressure/Time Curve and Flow/Time Curve. It is possible to
select which curves are displayed however the preset will be to display both Pressure/Time and
Flow/Time.
9. Pressure Gauge
Solid Green: Indicates the
pressure applied by the ventilator
during the respiratory cycle
Dotted Red Line: Indicated the
maximum pressure under current
settings
10. Pressure/Time Curve
The Pressure/Time Curve gives us a graphic representation of the changes in pressure applied to the lung.
The morphology of this curve changes based on the ventilation mode and based on the compliance of
the patient’s lungs and airway resistance. Advanced interpretation may able to help troubleshoot
ventilator problems. The ventilator is also able to measure plateau pressures and leak which may be
helpful during ventilator emergencies.
11. Pressure/Time Curve
• An example of when the Pressure/Time Curve may help us ventilate a
patient
• The curve below is of a patient who due to extended transport time is
beginning to make respiratory efforts and is “fighting” the vent.
12. Flow/Time Curve
The Flow/Time Curve allows us the follow the flow in both the inspiratory and
expiratory phase. Positive deflections indicate inspiratory flow and negative
deflections indicate expiratory flow
13. Flow/Time Curve
• An example of when ventilator curves can help us is if we consider dynamic
hyperinflation
• In the curve below the expiratory flow curve never reaches the baseline suggesting that
the patient does not have sufficient time to exhale as may happen in patients with
bronchoconstriction
14. Troubleshooting
• Mechanical Ventilation troubleshooting can be approached if we
consider a 3 part model and that problems can occur in any of those
three parts
• Part 1: The Patient (Sensorium, Airway, Cardiopulmonary System)
• Part 2: Patient-Machine Connection (ETT tube; ventilator circuit and
connectors)
• Part 3: The Ventilator & Oxygen Source
15. Troubleshooting
• DOPE Mnemonic
• D isplacement of endotracheal tube
• O bstruction of endotracheal tube
• P neumothorax
• E quipment Failure
• ARHT Emergency Checklists
• EtCO2 Morphology and Ventilator Curves may be helpful
• When in doubt switch to BVM
16. Ventilator Alarms
Clinically Important Ventilator Alarms
- High Airway Pressure
- Low Airway Pressure
- Apnea
- Increased PEEP
- Low Oxygen Pressure
In addition some causes of abnormal
EtC02 values/trends as well Hypoxia can
be addressed or be due to mechanical
ventilation and the patient/ventilator
interface
18. Non-Invasive Ventilation (NIV)
• A new capability with the Standard 2 is NIV. The two NIV modes are CPAP
and BiPaP which can provide ventilator support and potentially avoid
intubation in a subset of our patients
• CPAP mode is a means of providing continuous pressure without the use of
a BVM and PEEP valve. This can be helpful for CHF patients and is described
in the SJA CPG’s
• BiPAP provides both continuous pressure support as well as inspiratory
pressure. This can be helpful for selected patients including those with CHF,
CORD/Asthma Patients and Neuromuscular disorders
• NIV may also be useful as means of pre-oxygenation prior to RSI in a subset
of patients
19. Successful use of NIV is highly dependent on…
1) Patient Selection
2) Consideration of Contraindications
3) Proper Mask-Fitting
4) Continuous Monitoring and Patient Re-
Assessment
5) Being Prepared to Intubate if Necessary