Carbohydrates are one of the major classes of biological molecules and are the most abundant. They have many important functions including energy storage, structural components, and cell signaling. Carbohydrates exist as monomers, dimers, oligomers, and polymers. Monosaccharides like glucose and fructose are the simplest units and exist as open chains or rings. Isomers have the same molecular formula but different structures. Cyclization of monosaccharides forms rings called pyranoses and furanoses. The document defines important carbohydrate terms and classifications.
bio chemistry
كيمياء حيوية جامعة الملك سعود
chemistry
كيمياء جامعية
0503964728
محمد منير كيمياء
ابو يوسف
all branched of chemistry bio chemistry - organic chemistry - inorganic chemistry - analytically - spectra - d-block
bio chemistry
كيمياء حيوية جامعة الملك سعود
chemistry
كيمياء جامعية
0503964728
محمد منير كيمياء
ابو يوسف
all branched of chemistry bio chemistry - organic chemistry - inorganic chemistry - analytically - spectra - d-block
Basic biochemistry of Carbohydrates suitable for undergraduate students.
This presentation has been started from the basics to enable easy understanding.
This presentation is made for F.Y.Bsc. Students.
The presentation includes the General Properties of Carbohydrate and the classification of carbohydrates.
Introduction to Carbohydrates and its ChemistryDHANANJAY PATIL
A Comprehensive Introduction to Carbohydrates its chemistry, classification, qualitative tests an disorders related to its metabolism. This will give readers a overall insight to this topic. All types of queries and suggestions are most welcome
WHAT IS CARBOHYDRATE? CLASSIFICATION OF CARBOHYDRATE? WHAT IS MONOSACCHARIDE? CLASSIFICATION OF MONOSACCHARIDE. PHYSICAL PROPERTY. CHEMICAL PROPERTY. ATRUCTURAL FORMULA. METABOLISM . IMPORTANCE OF MONOSACCHARIDE. IMPORTANT FACT RELATED TO MONOSACCHARIDE. DISORDER OF MONOSACCHARIDE CONCLUSION. REFRANCES
History
Introduction
Functions
Classification – Monosaccharides
Disaccharides
Oligosaccharides
Polysaccharides
Digestion of carbohydrates
Absorption of carbohydrates
Dietary guidelines
Carbohydrates and oral health
Nutritional health programs in India
Public health significance
Carbohydrates: Monosaccharides- structure and functionDr. GURPREET SINGH
this presentation describes about the structure of carbohydrates in detail with specific reference to monosaccharides, their classification, structural component and functions
Monosaccharides are simple sugar molecules. These molecules have different configurations due to which various isomeric forms are formed. The structure of monosaccharides help to understand the positions of H and OH in the structure and the aldehyde and keto groups.
Basic biochemistry of Carbohydrates suitable for undergraduate students.
This presentation has been started from the basics to enable easy understanding.
This presentation is made for F.Y.Bsc. Students.
The presentation includes the General Properties of Carbohydrate and the classification of carbohydrates.
Introduction to Carbohydrates and its ChemistryDHANANJAY PATIL
A Comprehensive Introduction to Carbohydrates its chemistry, classification, qualitative tests an disorders related to its metabolism. This will give readers a overall insight to this topic. All types of queries and suggestions are most welcome
WHAT IS CARBOHYDRATE? CLASSIFICATION OF CARBOHYDRATE? WHAT IS MONOSACCHARIDE? CLASSIFICATION OF MONOSACCHARIDE. PHYSICAL PROPERTY. CHEMICAL PROPERTY. ATRUCTURAL FORMULA. METABOLISM . IMPORTANCE OF MONOSACCHARIDE. IMPORTANT FACT RELATED TO MONOSACCHARIDE. DISORDER OF MONOSACCHARIDE CONCLUSION. REFRANCES
History
Introduction
Functions
Classification – Monosaccharides
Disaccharides
Oligosaccharides
Polysaccharides
Digestion of carbohydrates
Absorption of carbohydrates
Dietary guidelines
Carbohydrates and oral health
Nutritional health programs in India
Public health significance
Carbohydrates: Monosaccharides- structure and functionDr. GURPREET SINGH
this presentation describes about the structure of carbohydrates in detail with specific reference to monosaccharides, their classification, structural component and functions
Monosaccharides are simple sugar molecules. These molecules have different configurations due to which various isomeric forms are formed. The structure of monosaccharides help to understand the positions of H and OH in the structure and the aldehyde and keto groups.
Glycogen is the storage from of glucose. The metabolism of glycogen both as glycogenolysis, breakdown of glycogen, and glycogenesis, formation of glycogen along with their regulation is briefed in the slides.
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Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. Biochemistry is the application of chemistry to the study of biological processes at the cellular and molecular level. It emerged as a distinct discipline around the beginning of the 20th century when scientists combined chemistry, physiology, and biology to investigate the chemistry of living systems.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2. INTRODUCTION
Carbohydrates are one of the three major
classes of biological molecules.
Carbohydrates are also the most
abundant biological molecules.
Carbohydrates derive their name from the
general formula Cn (H2O).
3. FUNCTIONS
Variety of important functions in living
systems:
nutritional (energy storage, fuels,
metabolic intermediates)
structural (components of nucleotides,
plant and bacterial cell walls, arthropod
exoskeletons, animal connective tissue)
informational (cell surface of eukaryotes --
molecular recognition, cell-cell communication)
4. Carbohydrates also can combine with
lipids to form glycolipids
OR
With proteins to form glycoproteins.
9. ASYMMETRIC CARBON
A carbon linked to four different atoms or
groups farthest from the carbonyl carbon
Also called Chiral carbon
10.
11. ISOMERS
Isomers are molecules that have the same
molecular formula, but have a different
arrangement of the atoms in space.
(different structures).
14. Examples of isomers:
1. Glucose
2. Fructose
3. Galactose
4. Mannose
Same chemical formula C6 H12 O6
15. EPIMERS
EPIMERS are sugars that differ in
configuration at ONLY 1 POSITION.
Examples of epimers :
D-glucose & D-galactose (epimeric at
C4)
D-glucose & D-mannose (epimeric at
C2)
D-idose & L-glucose (epimeric at C5)
20. The two members of the pair are
designated as D and L forms.
In D form the OH group on the
asymmetric carbon is on the right.
In L form the OH group is on the left
side.
D-glucose and L-glucose are
enantiomers:
21.
22.
23.
24. CYCLIZATION
Less then 1%of CHO exist in an open
chain form.
Predominantly found in ring form.
involving reaction of C-5 OH group with
the C-1 aldehyde group or C-2 of keto
group.
25. Six membered ring structures are called
Pyranoses .
five membered ring structures are called
Furanoses .
29. ANOMERIC CARBON
The carbonyl carbon after cyclization becomes
the anomeric carbon.
This creates α and β configuration.
In α configuration the OH is on the same of the
ring in fischer projection. In Haworths it is on
the trans side of CH2OH.
30. Such α and β configuration are called
diastereomers and they are not mirror images.
Enzymes can distinguished between these two
forms:
Glycogen is synthesized from α-D
glucopyranose
Cellulose is synthesized from β -D
glucopyranose
31. MUTAROTATION
Unlike the other stereoisomeric forms, α
and β anomers spontaneously
interconvert in solution.
This is called mutarotation.
32.
33. OPTICAL ACTIVITY
When a plane polarized light is passed through a
solution containing monosaccharides the light
will either be rotated towards right or left.
This rotation is because of the presence of
asymmetric carbon atom.
If it is rotated towards left- levorotatory (-)
If it is rotated towards right-
dextrorotatory(+)
34. REDUCING SUGAR
Sugars in which the oxygen of the
anomeric carbon is free and not attached
to any other structure, such sugars can
act as reducing agents and are called
reducing sugars.
36. Monosaccharides- one unit of
carbohydrate
Disaccharides- Two units of
carbohydrates.
Anywhere from two to ten monosaccharide
units, make up an oligosaccharide.
Polysaccharides are much larger,
containing hundreds of monosaccharide
units.
37. 1.Monosaccharides
The monosaccharide commonly found in humans are classified
according to the number of carbons they contain in their backbone
structures.
Classifications
Trioses (C3
H6
O3
) Glycerose
(glyceraldehyde)
Dihydroxyacetone
Tetroses (C4
H8
O4
) Erythrose Erythrulose
Pentoses (C5
H10
O5
) Ribose Ribulose
Hexoses (C6
H12
O6
) Glucose Fructose
Heptoses (C7
H14
O7
) — Sedoheptulose
ALDOSES KETOSES
38. Pentoses of Physiologic Importance.
Sugar Source Biochemical and Clinical Importance
D-Ribose Nucleic acids and
metabolic intermediate
Structural component of nucleic acids
and coenzymes, including ATP,
NAD(P), and flavin coenzymes
D-Ribulose Metabolic intermediate Intermediate in the pentose phosphate
pathway
D-Arabinose Plant gums Constituent of glycoproteins
D-Xylose Plant gums,
proteoglycans,
glycosaminoglycans
Constituent of glycoproteins
L-Xylulose Metabolic intermediate Excreted in the urine in essential
pentosuria
39. Hexoses of Physiologic Importance.
Sugar Source Biochemical Importance Clinical Significance
D-Glucose Fruit juices, hydrolysis of
starch, cane or beet sugar,
maltose and lactose
The main metabolic fuel for
tissues; "blood sugar"
Excreted in the urine
(glucosuria) in poorly
controlled diabetes
mellitus as a result of
hyperglycemia
D-Fructose Fruit juices, honey,
hydrolysis of cane or beet
sugar and inulin, enzymic
isomerization
of glucosesyrups for food
manufacture
Readily metabolized either
via glucoseor directly
Hereditary fructose
intolerance leads to
fructose accumulation
and hypoglycemia
D-Galactose Hydrolysis of lactose Readily metabolized to glucose;
synthesized in the mammary
gland for synthesis of lactose in
milk. A constituent of
glycolipids and glycoproteins
Hereditary galactosemia
as a result of failure to
metabolize galactose
leads to cataracts
D-Mannose Hydrolysis of plant
mannan gums
Constituent of glycoproteins