Glycogenolysis is the breakdown of glycogen into glucose. It occurs primarily in the liver and muscles, where the key enzyme glycogen phosphorylase catalyzes the shortening and removal of chains and branches from glycogen to produce glucose-1-phosphate and then glucose-6-phosphate. Glycogenolysis is regulated through the activation of phosphorylase and its inhibitor, as well as the role of calcium in stimulating glycogen breakdown in muscles.

1. Carbohydrate metabolism
GLYCOENOLYSIS

2. GLYCOENOLYSIS
• Break down of glycogen into glucose
• It takes place in liver ad muscles
• Key enzyme is glycogen phosphorylase

3. Reactions
• Shortening of chains
• Removal of branches
• Glucose-1-phosphate to G-6-Phosphate

5. Other pathway
• Lysosomal degradation(alpha amylosis)
• Gemma-amylosis

6. Regulation
• Activation of Phosphorylase
• Activation of inhibitor-1
• Role of calcium in glycogenolysis in muscles