This document outlines the syllabus for a course on Immunology & Bacterial Serology. The course has 5 units that cover basic immunology, antigen-antibody reactions, serological tests, the complement system, and autoimmunity and vaccines. Students will learn about immunity, antigens, immunoglobulins, antigen-antibody reactions like precipitation and agglutination, serological tests like Widal and VDRL, complement activation pathways, and autoimmune diseases and vaccination schedules. The course aims to explain different types of immunity and immune cells, differentiate antigen-antibody reactions, demonstrate serological test principles and interpretations, and explain autoimmunity, vaccines, and immune responses.

1. IMMUNOLOGY & BACTERIAL SEROLOGY
NOTES
SUB CODE: BMLT4002
DEPARTMENT OF MEDICAL LAB
TECHNOLOGY
SMAS
FACULTY INCHARGE: Mr. A. VAMSI KUMR (Asst Prof)

2. SYLLABUS
COURSE OUTCOMES
On completion of this course the students will able to:
1. Explain the different types of immunity, immune cells, structure & types of Antigen
and immunoglobulins
2. Differentiate general features, mechanism, applications of different types of Antigen-
Antibody reaction
3. Demonstrate the principle, procedure, interpret various serological tests
4. Generalize compliment activation pathways and types of immune response
5.
Explain autoimmunity, auto immune diseases, Vaccination schedule

3. SYLLABUS
Unit 1
Basic Immunology Number of Lecture Hours 8
Basic Immunology: History and introduction to immunology, Immunity; Innate & Acquired
immunity- mechanisms mechanism of immunity; Definition, types of antigens and determinants
of antigenicity ; Definition, types, structure and properties of immunoglobulin
Pedagogy
tools
Scaleup Lecture
Unit 2
Antigen Antibody reaction Number of Lecture Hours 10
Antigen Antibody reaction: Antigen-Antibody reactions-Definition, Classification, General
features and mechanisms , Applications of Preciptation, Agglutination, Immunodiffussion
Complement fixation test, Immuno- fluorescence, RIA , ELISA
Pedagogy
tools
Scaleup Lecture
Unit 3
Serological Tests Number of Lecture Hours 6
Serological Tests: Principle, procedure and interpretation of various serological tests: Widal
VDRL, ASO, CRP, Brucella tube agglutination, Rose-Waaler
Pedagogy
tools
Scaleup Lecture
Unit 4
Complement system Number of Lecture Hours 8
Complement system: Definition, complement activation pathways
Immune response: Introduction & Basic concepts of Humoral and Cellular immune
Pedagogy
tools
Scaleup Lecture
Unit 5 Auto Immunity and Vaccines Number of Lecture Hours 8
Auto Immunity: Basic concepts of autoimmunity and brief knowledge about autoimmune
diseases Vaccines: Definition, Types, Vaccination schedule
Reference:
1. Text book of Microbiology by Ananthanarayanan. S
2. Text book of Microbiology: CP. Baveja
3. Text book of immunology by: SK: Gupate
4. Practical Medical Microbiology by Mackie & McCartney Volume 1 and 2
5. Medical Microbiology by Paniker & Satish Gupte
6. Medical laboratory Technology Vol. I ,II, III by Mukherjee
7. Medical Laboratory manual for tropical countries Vol II Microbiology by Monica Cheesbrough
8. Practical Medical Microbiology by Mackie & McCartney Volume 1 and 2

4. Course Name/ code Immunology & Bacterial serology / BMLT4002
Unit/ Module/ CO 1
Area & Topic Introduction to Innate Immunity
Faculty In charge Mr. A. Vamsi Kumar (Asst Prof)
Department / School Medical lab technology, SMAS
Semester IV
1. INTRODUCTION TO BASIC IMMMUNNOLOGY
Introduction: