This course offers Medical Lab Technology students a comprehensive insight into Clinical Pathology and Histopathology through a series of visits to these laboratories. Through structured units, students will gain foundational knowledge, observe advanced techniques, and explore emerging trends in these fields. They will also apply their knowledge through a series of relevant case studies. Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com

1. B.Sc. MLT Syllabus
Attuluri Vamsi Kumar I Assistant professor I Dept of MLT I Ph No: 7416660584 I Website: mltmaster.com
Website: www.mltmaster.com I YouTube: https://www.youtube.com/@vamsiMLT
Program Name: B.Sc. Medical Lab Technology
Syllabus of Clinical Laboratory Visit - III
Course Name: Clinical Laboratory Visit - III Course Type
Course Coordinator: Attuluri Vamsi Kumar – B.Sc. MLT, M.Sc. MLT, PhD (Perusing)
Designation: Assistant Professor
Department: Department of Medical Lab Technology (MLT)
Skill
Enhancement
PRE-REQUISITE Clinical Laboratory Visit - II Sem: 4 S. No: 32
About Vamsi: I am academician in Medical Laboratory Sciences with a strong desire to improve Outcome
based education (OBE) structured MLT education. I am constantly focusing on building an academic
atmosphere that is set high standards with strong multi blended teaching pedagogy models.
YouTube: https://www.youtube.com/@vamsiMLT
SlideShare: https://www.slideshare.net/VamsiIntellectual
Website: www.mltmaster.com / https://sites.google.com/view/vamsi-intellectual-protfolio/home
LinkedIn: https://www.linkedin.com/in/vamsi-kumar-attuluri-ab8987128/?originalSubdomain=in
Research Gate: https://www.researchgate.net/profile/Attuluri-Kumar
Orcid ID: https://orcid.org/0000-0001-9278-6714
Contact No: +91 7416660584
Mail ID: vamsifmlt@gmail.com
A. COURSE DESCRIPTION
This course offers Medical Lab Technology students a comprehensive insight into Clinical
Pathology and Histopathology through a series of visits to these laboratories. Through
structured units, students will gain foundational knowledge, observe advanced techniques, and
explore emerging trends in these fields. They will also apply their knowledge through a series
of relevant case studies.
B. COURSE OBJECTIVES:
1. List and describe the basic and advanced techniques used in Clinical Pathology and
Histopathology.
2. Explain the processes involved in tissue collection, processing, staining, and microscopic
examination in Histopathology.
3. Apply the principles of Clinical Pathology to interpret results of common laboratory tests as
demonstrated through the case studies.
4. Analyze the role of emerging technologies such as AI and Next-Generation Sequencing in the
advancement of Clinical Pathology and Histopathology.
5. Combine theoretical knowledge and case study findings to understand the future prospects of
Clinical Pathology and Histopathology.
C. COURSE OUTCOMES
CO
No
Statement Performance
Indicator
Level of
Learning
(Highest BT
Level)
Target
Attainment
CO1 Recognize and recall the fundamental concepts,
techniques, and procedures in Clinical Pathology
and Histopathology.
PI 2, PI 2.1, PI
2.2, PI 2.3, PI
2.4, PI 2.5, PI
6
Knowledge (K1) 70%
CO2 Understand the methodologies in tissue processing,
staining, and microscopic examination, and interpret
the results of common laboratory tests.
PI 2.5, PI 2.6,
PI 2.7, PI 2.8,
PI 3
Comprehension
(K2)
70%

2. B.Sc. MLT Syllabus
Attuluri Vamsi Kumar I Assistant professor I Dept of MLT I Ph No: 7416660584 I Website: mltmaster.com
Website: www.mltmaster.com I YouTube: https://www.youtube.com/@vamsiMLT
CO3 Utilize the knowledge gained in the field of Clinical
Pathology and Histopathology to solve relevant case
studies and real-world problems.
PI 2, PI 3, PI
4, PI 6
Application
(K3)
70%
CO4 Examine and analyze the role of emerging
technologies and trends in Clinical Pathology and
Histopathology.
PI 6, PI 7, PI 8 Analysis (K4) 70%
CO5 Integrate theoretical knowledge and practical skills
to understand the future prospects and challenges in
Clinical Pathology and Histopathology.
PI 2, PI 2.5, PI
2.9, PI 6, PI 7
Synthesis (K5) 70%
CO6 Evaluate the impact and implications of Clinical
Pathology and Histopathology in the context of
public health, pandemic preparedness, and
personalized medicine.
PI 1, PI 2, PI
2.5, PI 2.8, PI
9, PI 10
Evaluation (K6) 70%
D. SYLLABUS
Unit-1 Introduction to Clinical Pathology and Histopathology Contact Hours:15
Chapter 1.1 Fundamentals of Clinical Pathology- Introduction to Clinical Pathology
Laboratory Safety and Standard Practices
Pre-analytical, Analytical, and Post-analytical Processes
Types of Pathology Tests
Chapter 1.2 Introduction to Histopathology- Basics of Histopathology
Tissue Collection, Processing, and Staining
Microscopic Examination
Experiment 1 /
Case study
Case study: Interpretation of a Full Blood Count
Experiment 2 /
Case study
Case study: Navigating an Unexpected Result in Clinical Pathology
Experiment 3 /
Case study
Case study: Handling Biopsy Samples in Histopathology
Unit-2 Advanced Techniques in Clinical Pathology and
Histopathology
Contact Hours:15
Chapter 2.1 Advanced Techniques in Clinical Pathology - 32
Chapter 2.2 Advanced Techniques in Histopathology- Immunohistochemistry and In Situ Hybridization
Digital Pathology and Telepathology
Automation in Histopathology
Experiment 4 /
Case study
Case study: The Role of Molecular Diagnostics in Infectious Disease, Case of Complex
Transfusion Reaction
Experiment 5 /
Case study
Case study: Analyzing a Case of Prostate Cancer with Immunohistochemistry,Implementing
Digital Pathology in a Clinical Laboratory
Experiment 6 /
Case study
Casestudy:Application of Telepathology for Remote Diagnoses
Experiment 7 /
Case study
Case study:Automation in Histopathology: Pros and Cons
Unit-3 Special Topics in Clinical Pathology and Histopathology Contact Hours:15
Chapter 3.1 Emerging Trends in Clinical Pathology- Personalized Medicine and Clinical Pathology
Clinical Pathology in Pandemic Preparedness
The Role of Clinical Pathology in Public Health
Chapter 3.2 Emerging Trends in Histopathology- Next-Generation Sequencing and its Impact on
Histopathology
The Future of Digital Pathology
AI and Machine Learning in Histopathology

3. B.Sc. MLT Syllabus
Attuluri Vamsi Kumar I Assistant professor I Dept of MLT I Ph No: 7416660584 I Website: mltmaster.com
Website: www.mltmaster.com I YouTube: https://www.youtube.com/@vamsiMLT
Experiment 8 /
Case study
Case study: The Role of Clinical Pathology in a Recent Pandemic, Personalized Medicine:
Case Study of a Patient with Rare Genetic Disorder, AI Assisted Diagnosis in Histopathology:
A Promising Future
Experiment 9 /
Case study
Case study: The Impact of Next-Generation Sequencing on a Complex Case,
Handling Public Health Crisis with Clinical Pathology,
AI and Machine Learning in Histopathology: A Case Study
Experiment 10 /
Case study
Case study: Transformative Power of Digital Pathology: A Case Review, The Potential of
Clinical Pathology in Disease Outbreak Management, Genomic Medicine and its Impact on
Histopathology: A Case Study, The Role of Clinical Pathology in Epidemic Surveilla
Self-study topics for Advance learners: -
E. TEXT BOOKS/REFERENCE BOOKS
TEXT BOOKS
T1 "Clinical Laboratory Science" by Mary Louise Turgeon
T2 "Robbins Basic Pathology" by Vinay Kumar, Abul K. Abbas, Jon C. Aster
T3 "Molecular Diagnostics: Fundamentals, Methods, and Clinical Applications" by Lela
Buckingham and Maribeth L. Flaws
REFERENCE BOOKS
R1 "Immunohistochemistry: Basics and Methods" by Peter G. Isaacson and David G.
Bostwick
R2 "Personalized Medicine: Principles and Practices" by Michael Snyder and Leroy Hood
R3 "Next-Generation Sequencing: Translational Medicine and Personalized Health Care" by
Jian Han and Hesham Ali

4. B.Sc. MLT Syllabus
Attuluri Vamsi Kumar I Assistant professor I Dept of MLT I Ph No: 7416660584 I Website: mltmaster.com
Website: www.mltmaster.com I YouTube: https://www.youtube.com/@vamsiMLT
Code Performance Indicators
PI 1 Demonstrate professional interpersonal, oral, and written communications skills sufficient to
serve the needs of patients and the public including an awareness of how diversity may affect
the communication process.
PI 2 Perform pre-analytical, analytical, and post-analytical processes:
PI 2.1 Demonstrate ability to understand investigation/test requisition.
PI 2.2 Collecting the relevant clinical samples along with complete and accurate documentation with
proper safety measures in relation to sample accountability.
PI 2.3 To transport the samples with precautionary measures to the relevant lab section.
PI 2.4 Demonstrate the ability to prepare clinical sample for processing
PI 2.5 To demonstrate the knowledge of accurate sample processing for the required lab
investigation. Perform routine clinical laboratory tests in clinical chemistry,
haematology/haemostasis, immunology, immunohematology, microbiology, Histopathology,
Cytopathology, body fluid analysis, and laboratory operations.
PI 2.6 Perform mathematical calculations related to all areas of the clinical laboratory
PI 2.7 Ability to record the test results/data.
PI 2.8 To demonstrate the ability to interpret the test reports and its documentation in lab records.
PI 2.9 Demonstrate ability to release the report to the right person in minimum turn-around time
(TAT).
PI 3 Perform problem solving and troubleshooting techniques for laboratory methodologies
Correlate laboratory test results with patient diagnosis and treatment.
PI 4 To follow basic quality assessment protocol of clinical laboratory.
PI 5 Demonstrate routine laboratory techniques sufficient to orient new employees within the
clinical laboratory.
PI 6 Apply basic scientific principles in learning new techniques/procedures; demonstrate
application of principles and methodologies.
PI 7 Utilize computer technology applications to interact with computerized instruments and
laboratory information systems.
PI 8 Demonstrate adequate knowledge of computer software as it applies to document production,
spreadsheets, and presentations.
PI 9 Demonstrate professional behaviour with co-team mates.
PI 10 Demonstrate sensitivity and compassion towards patients.