Powepoint presentation on the Nervous System, its function and composition. Nerves and neurons - Nerve impulses- Synapse- Reflex action- Reflex arc. - Notes on the eye. links to further study
Powepoint presentation on the Nervous System, its function and composition. Nerves and neurons - Nerve impulses- Synapse- Reflex action- Reflex arc. - Notes on the eye. links to further study
Mr Exham IGCSE - Cell Differentiation and Organisationmrexham
This is a presentation designed to help explain the section of the Edexcel IGCSE Biology course about cell differentiation and organisation. For more help with IGCSE Biology please visit mrexham.com
IGCSE Biology 0610 - Introduction to Biology - Characteristics of living orga...Vasiliki Makrygianni
IGCSE Biology 0610/ Syllabus 2020-2022/
Coursebook: Cambridge IGCSE Biology Coursebook (third edition), Mary Jones and Geoff Jones, Cambridge University Press.
note: free to share and use ...is designed for level B1-B2. cheers,...
Mr Exham IGCSE - Cell Differentiation and Organisationmrexham
This is a presentation designed to help explain the section of the Edexcel IGCSE Biology course about cell differentiation and organisation. For more help with IGCSE Biology please visit mrexham.com
IGCSE Biology 0610 - Introduction to Biology - Characteristics of living orga...Vasiliki Makrygianni
IGCSE Biology 0610/ Syllabus 2020-2022/
Coursebook: Cambridge IGCSE Biology Coursebook (third edition), Mary Jones and Geoff Jones, Cambridge University Press.
note: free to share and use ...is designed for level B1-B2. cheers,...
IGCSE Biology - Chemical Coordination in Plantsmrexham
This PowerPoint answers the following questions:
Do you understand that plants respond to stimuli?
Can you give an example of positive phototropism?
How do plant roots and stems respond to gravity?
It covers section 3.3 of the IGCSE Edexcel Biology Course.
This is the first PowerPoint in the mrexham IGCSE Biology series. It is also available on iBooks.
It covers the Cells section from life processes of the Edexcel IGCSE Biology course
The nervous system helps in controlling and coordinating various activities of the human body. The three types of nerves, cranial nerves, spinal nerves and visceral nerves run through the body and help in sending and receiving messages in the form of electrical impulses.
Here's a brief introduction to control and coordination class 10 science:
"Control and coordination are fundamental processes in living organisms that ensure proper functioning and response to stimuli. In simpler terms, control refers to the regulation of various activities within an organism, while coordination involves the harmonious integration of these activities. In humans and many other animals, control and coordination are primarily carried out by the nervous system and the endocrine system. The nervous system allows for rapid responses to stimuli through nerve impulses, while the endocrine system regulates physiological processes using chemical messengers called hormones. Together, these systems ensure that organisms can adapt to changes in their environment, maintain internal balance (homeostasis), and carry out essential functions for survival and well-being."
For more information, visit- www.vavaclasses.com
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
1. B Y :
A D E L I N E L A U R E N
C L A R I S S A
G E R A L V I N M N O R A L I M
J A S O N J A Y A L I E
O W E N J O N G
R U I Z O R L A N D O
Biology
Chapter 13 : The Nervous System
2. Sensitivity
A living organism is able to react to
changes in the surrounding.
The change in the environment that
cause an organism to react is called a
stimulus.
An organism’s reaction to a stimulus is
called a response.
The ability to respond to a stimulus is
known as sensitivity or irritability.
3. An organism usually responds to a stimulus by moving in a way
that benefits itself. For example:
Plant needs light for photosynthesis, so they
grow towards the light. This response occurs
over time.
Euglena, a single-celled organism, makes food
by photosynthesis. Euglena swims towards the
light.
Cockroaches, move away from the light. They
hide in dark areas during the day.
4. What is the role of the nervous system in
humans?
The nervous system in humans controls the activities of the body and
how it reacts to the surroundings.
The nervous system consist of a brain, spinal cord, spinal nerves and
highly specialized sense organs.
Sense organs:
• help the body to adjust to any
changes in the environment
• Enable the various parts of the
body to coordinate with one
another
5. In humans, many activities such as the heartbeat, peristalsis
and breathing movements are automatic and are not
controlled consciously. They are called involuntary actions.
Activities that are controlled consciously are called voluntary
actions.
Voluntary and involuntary actions
6. Thoughtless action
Sea anemone are some of the simplest animals under the sea, they do
not even have brains.
When a prey such as small fish brush against a sea anemone’s
tentacles, stinging cells in the tentacles are stimulated. The sea anemone
responds by stinging the prey. This is called as involuntary action.
7. Human nervous system
Component of the human nervous system:
-The central nervous system (CNS) consisting of the brain and
the spinal cord
-The peripheral nervous system (PNS) consisting of the cranial
nerves (nerves from the brain) and spinal nerves (nerves from
the spinal cord) and the sense organs.
8. -Sense organs are used to detect stimuli, they are also called receptors.
They inform the central nervous system about changes in the
surroundings, by producing electrical messages called nerve impulses.
These nerve impulses are transmitted through the peripheral nervous
system to the central nervous system.
10. Motor end plate
Dendron
Cell body contains a
nucleus, cytoplasm, cell
surface membrane and
organelles.
The nerve fibers
that transmit
nerve impulses
towards the cell
body are called
dendrons.
The dendrites of
a dendron of a
motor neuron
receives nerve
impulses from
other neurons
The nerve fibers
that transmit
nerve impulses
away from the
cell body are
called axons
The layer of
fatty
substances
enclosing
many nerve
fibers is the
myelin
sheath.
The region where the
myelin sheath is
absent are called
nodes of ranvier.
The axon
terminals of a
motor neuron
transmit nerve
impulses to the
effector.
The junction between the axon
terminal and the muscle fiber
is the motor end plate.
12. What is a
synapse?
Definition of synapse:
A synapse is a junction between 2 neurones, or a
junction between a neurone and an effector such
as a muscle or a gland
At a synapse, impulses are
transmitted from the
axon of one neurone to
the dendron of another
neuron ( or the cells of
the effector) across the
tiny space
Nerve impulse are
transmitted across the
synapse by certain
chemicals released by
the neurone. These
chemicals are called
neurotransmitters
13. What are nerves?
A nerve is a bundle of
nerve fibres enclosed in a
sheath of connective
tissue.
Nerve may emerge from the brain (cranial
nerve) or spinal cord (spinal nerve). They may
contain:
• Sensory nerve only – conduct nerve
impulses from sense organs.
• Motor nerve fibres only – conduct nerve
impulses from effectors.
• Mixed fibres (both sensory and motor nerve
fibres) – located in spinal nerves.
14. Brain
Forebrain:
• Concerned with
intelligence,
memory, learning
sensations and
overall control of
all voluntary
actions in human
• Concerned with the
regulation of body
temperature and
water potential of
blood, appetite,
sleep and emotions
• Produces and
relase many
important
The human brain can be divided into 3 parts: the
forebrain, the midbrain, and the hindbrain
Midbrain:
•Concerne
d with
sight and
visual
reflexes,
e.g.
movement
of the
eyeballs
Forebrain:
• Controls
muscular
coordination,
especially
maintaining
balance
• Controls
involuntary
actions, e.g.
the heartbeat,
peristalsis, the
rate of
respiratory
15. Distribution of the grey matter and white matter
in the central nervous system
Grey matter
The grey matter consist of mainly of the
cell bodies of the neurones .
It forms the outer layers of the brain and
the central parts of spinal cord
White matter
The white matter consist of mainly of
nerve fibres .
It forms the central parts of the brain,
and the outer layers of the spinal
cord.
Central canal
The central canal contains
a fluid called cerebrospinal
fluid that brings nutrients
to spinal cord
16. As the spinal nerves leave the spinal cord, it
branches itself into nerve fibres which is supplied
to different parts of our body
• Before the spinal nerve joins the spinal cord, it
is divided into two roots :
a) Dorsal root ( towards the back )
b) Ventral root ( towards the front )
17. 1. Sensory neuron in the spinal cord
transmit impulses to the relay neuron in
the brain
2. Relay neuron in the brain transmit
impulses back to the motor neuron in
the spinal cord
Remember !
The relay neurons
synapse with the
sensory and motor
neurons to enable the
transmission of nerve
impulses from the
sensory to motor
neurons
18. Dorsal root ganglion
• A small swelling in the
dorsal root containing cell
bodies of sensory neurons
Dorsal root
• Joints the back part
of the spinal cord
• It contains nerve
fibres of sensory
neurons that
transmit impulses to
the spinal cord
Ventral root
• Joins the front part of
the spinal cord
• It contains only nerve
fibres of motor
neurons that transmit
impulses from the
spinal cord
Spinal nerve
(mixed nerve)
• Form by the joining
of dorsal and ventral
root
• Contains both
sensory and motor
neurons
19. Sensation
When you touch a piece of ice, you can feel its coldness. This is because the
temperature receptor in in your skin is stimulated. Impulses are produced.
Impulses are transmitted to the forebrain. The brain interprets the impulses,
and you have a sensation of coldness.
The pathway of impulses is as follows:
Receptor in skin sensory neurone relay neurone in spinal cord
forebrain
20. voluntary actions
Voluntary action is a deliberate action, for example, you decide to raise
your hand to answer a question in class.
The pathway of impulses is as follow:
Forebrain relay neurone in spinal cord motor neurone effector
21. Reflex Action
Reflex action is an immediate response to a specific
stimulus without conscious control
It is an involuntary action
Classified into :
- Cranial reflexes
- Spinal reflexes
The spinal cord and the brain are reflex centres
26. The nervous system
Central nervous system
(CNS)
Peripheral nervous system
(PNS)
Brain Spinal cord Receptors Nerves
- Controls
voluntary
actions by
generating
nerve
- Controls
cranial
reflexes
e.g.
salivation
- transmit
nerve
impulses
to and
from brain
- controls
spinal
reflexes .e.g.
knee-jerk
reflex
Receive
stimuli from
the
environment
Cranial nerves
-sensory nerves
transmit impulses
from receptors to the
brain.
-Motor nerves
transmit impulses
from brain to
effectors
Spinal nerves
-sensory nerves
transmit impulses
from receptors to
spinal cords .
- Motor nerves
transmit impulses
from spinal cord to
effectors
27. Nervous Tissues
Neurons
Sensory (receptor)
neuron
-Transmits nerve
impulses from
receptors to CNS
Relay (intermediate)
neurons
-found within CNS
-Transmits nerve
impulses from sensory
neurons to motor
neurons
Motor (effectors)
neuron
-transmits nerve
impulses from CNS to
effectors
Components of reflex arc
A sense
organ
(receptor)
A sensory
neuron
A relay
neuron in a
reflex center
(brain or
spinal cord)
A motor
neuron
An
effector