The human digestive system breaks down food mechanically and chemically so that nutrients can be absorbed and used by the body. Food passes through a series of organs, being broken down by enzymes and acid. The mouth, esophagus, stomach, small intestine, large intestine, rectum and anus all play a role in digestion. In the stomach, food is broken down by acid and enzymes. In the small intestine, the pancreas, liver and intestinal glands further break down food into molecules that can be absorbed. Undigested material then passes to the large intestine, where water and minerals are absorbed before waste is passed through the rectum and anus.